The invention belongs to the technical field of
human body electroencephalogram
signal processing and brain regulation and control. The invention provides an ultrasonic-electrical stimulation collaborative
lymphatic system enhanced closed-loop regulation and
control system, which integrates noradrenaline oscillation core driving signals to realize
sleep staging and conversion detection, decides an ultrasonic-electrical stimulation collaborative mode based on a staging
coupling index, completes parameter linear transition in a conversion period, and improves
sleep quality. Stimulation parameters are dynamically optimized in combination with
reinforcement learning and a PID fusion
algorithm. According to the device, the defects of core
signal deficiency, inaccurate stimulation coordination, one-sided
coupling analysis and poor safety adaptability of an existing device are overcome, the
lymphatic system metabolic waste removal efficiency is remarkably improved, the sleep interruption risk is reduced, regulation and control are accurate, safety and noninvasive are achieved, the device is suitable for prevention and
adjuvant therapy of neurodegenerative diseases such as Alzheimer's
disease, and the device has a wide application prospect. And the method can also be expanded to be used for lymphatic-like function mechanism research and
early disease screening.