43 results about "Sleep regulation" patented technology

The invention provides a multi-mode adaptive wave simulation control system and method for a deep sleep physiotherapy cabin. Belongs to the technical field of fluid mechanics and health intervention. The method comprises the steps that multi-modal physiological parameter collection is conducted on a user on a deep sleep physiotherapy cabin, a real-time physiological data set is generated, the current sleep stage of the user is deduced through a time-frequency analysis and machine learning model on the basis of the data set, a sleep stage label is generated, a pre-trained wave mode generator is dynamically called according to the sleep stage label, and the deep sleep physiotherapy cabin is obtained. An initial set of wave parameters matching the current sleep stage is generated. By sensing the physiological state of the user in a non-contact mode, deducing the sleep stage and dynamically generating and adjusting the wave modes such as sleep guiding and deep sleep maintaining, water fluctuation accurately adapts to the physiological requirements of the user in different sleep stages, a traditional static wave mode is abandoned, highly-personalized sleep adjusting experience is provided for the user, and the sleep quality is effectively improved.

The invention relates to a personalized sleep-aiding regulation and control method and system fusing multi-band characteristics and closed-loop feedback, and relates to the technical field of sleep regulation and control. According to the method, a cross-band coupling matrix is constructed, a nerve-physiological synergy index is calculated, environment-brain state interaction potential energy is calculated based on different band powers and environment sound pressure levels, and the nerve-physiological synergy index and the environment-brain state interaction potential energy are combined into a coupling state vector; solving the coupling state vector to judge the stability of the sleep state; on the basis, personalized sleep induction dynamic attractor intensity is calculated, and different sleep regulation and control strategies are generated according to the steady state / unsteady state and the corresponding attractor intensity. According to the invention, the unique sleep dynamics of the user can be understood and self-adaptively regulated.

The invention provides a sleep regulation and control method and device based on a non-invasive brain-computer interface, and belongs to the technical field of sleep regulation and control. The method specifically comprises the steps that the coincidence condition of a reliable user and a user with the environment temperature changing is determined and recognized, and verification data of a sleep stage recognition model for recognizing the reliable user are combined; determining an update processing strategy of the sleep staging identification model, performing update processing on the sleep staging identification model according to the update processing strategy of the sleep staging identification model, and determining the sleep staging identification model according to an update processing result of the sleep staging identification model and historical regulation and control data of the sleep environment temperature in the user with the environment temperature changing. According to the regulation and control method for determining the sleep environment temperature of the user with the environment temperature changing, determination of differentiated temperature regulation strategies of the sleep environment temperature under different staging results is achieved, and then the user experience is improved.

The invention provides a sleep music generation method and device and terminal equipment, and is suitable for the technical field of data processing, and the method comprises the steps: obtaining a sleep music generation result according to user age information, user gender information, current user physiological state information, current user behavior state information, historical user physiological state information and historical user behavior state information; obtaining current user rhythm information and current user sleep state characterization information; generating current user sleep state confirmation information according to the current user rhythm information and the current user sleep state representation information; and in response to the generation of the current user sleep state confirmation information, generating sleep music information according to the current user physiological state information, the sleep music generation model and a preset sleep music set. According to the method and the device, the individual difference of the user and the sleep state of dynamic change are accurately adapted, the accuracy and adaptability of sleep music generation are improved, and personalized sleep adjustment is effectively realized.

The invention discloses a multi-mode light-supplementing sleep-aiding control circuit, device and system integrating sound, light and smell, and a control method, and relates to the technical field of electronic circuits. The circuit comprises a main control module, a light supplementing module, a sleep-aiding lamplight module, an environment sensing module, an aromatherapy module, a power amplifier loudspeaker module and the like, low-blue-light soft and brightness-adjustable illumination is output through the light supplementing module, and the problems of too strong blue light, screen stroboflash and reading fatigue when an intelligent terminal is used are solved. The sleep-aiding light module can be adjusted to warm color temperature, the mood is relaxed, and illumination secreted by melatonin is not damaged. The environment sensing module collects environment light and proximity distance information in real time, so that the equipment can intelligently adjust the light supplementing brightness and the sleep-aiding lamp mode; hot fumigation closed-loop control is adopted for the aromatherapy module, constant-temperature adjustment is achieved through temperature sampling, and volatilization of sleep-aiding fragrance is more stable and safer; the power amplifier loudspeaker module provides stable output for white noise, natural sound and rhythmic respiration guiding sound, and provides reliable acoustic assistance for sleep adjustment.

1. Name of the product in this design: Cell membrane potential modulation machine. 2. Purpose of this design: To apply the principle of biomimetic pulsed magnetic resonance to regulate cell membrane potential, thereby improving sleep and regulating sub-health conditions. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention is applied to the field of sleep management, and discloses a sleep state recognition regulation and control method and system.The method comprises the steps that piezoelectric signal data captured by piezoelectric sensing equipment and optical pulse signal data captured by wearable sensing equipment in the sleep process of a target user are obtained; body movement artifact removal processing is conducted on the piezoelectric signal data and the optical pulse signal data, and first piezoelectric signal data and first optical pulse signal data are obtained; performing fusion processing on the first piezoelectric signal data and the first optical pulse signal data to obtain a target fusion feature; determining a sleep type of the target user based on the target fusion feature, performing sleep state recognition on the target fusion feature based on the sleep type, and generating a sleep core index corresponding to a recognition result; and according to the sleep type and the sleep core index, generating and executing a sleep regulation strategy of the target user. According to the method, the sleep quality of the user is improved.

The invention belongs to the technical field of microorganisms and compound nutrients, and particularly relates to a postbiotic preparation and composition for improving activity of gamma-aminobutyric acid and promoting calcium absorption and application of the postbiotic preparation and composition in sleep improvement and bone health. Through the synergistic effect of the specific metagen preparation and the gamma-aminobutyric acid, the multi-dimensional technical breakthrough is realized, and the physiological activity and the application value are remarkably improved. In the aspect of bioavailability, the intestinal barrier function is improved and the pH value of the intestinal tract is adjusted to be weakly acidic through the postbiotics, so that the concentration of serum GABA is increased by 2-3 times compared with that of single use, and the calcium absorption rate is increased from 30% to 55-60%. And on the aspect of function synergy, the limitation of single effect in the prior art is broken through, dual-function synergy of'sleep regulation-bone health 'is realized, meanwhile, the vicious circle of'poor sleep-calcium loss' is improved, and good practical application value is achieved.

The invention relates to the technical field of electronics, in particular to a sleep regulation strategy generation method and wristband device.The sleep regulation strategy generation method comprises the steps that first physiological signal data of a user in multiple time subunits are obtained; determining a first pressure state of each time subunit based on the first physiological signal data; when the first pressure state is greater than a preset pressure value, executing a preset target intervention strategy; acquiring a second pressure state of the user after intervention of each target intervention strategy; and determining a sleep regulation strategy according to all the first pressure states and the second pressure states. The invention mainly aims to provide a sleep regulation strategy generation method, and aims to perform targeted intervention and regulation aiming at the psychological stress of a user every day, so that the emotion of the user is relieved, and the sleep quality is improved.

The present application provides a propofol analogue, a preparation method thereof and application thereof in non-narcotic field. The propofol analogue has a structure as shown in general formula (G). The propofol analogue of the present application can greatly reduce or eliminate the affinity to GABA receptor, i.e. weaken or eliminate the narcotic property. It targets specific targets and shows effects in improving sleep, regulating blood pressure, relieving vomiting, resisting depression, protecting heart and brain, etc. (G).

This invention provides a method and system for binaural differential frequency sleep conditioning, aiming to solve the technical problems of existing sleep regulation methods being weakly targeted, easily affected by environmental interference, and difficult to adapt to different types of sleep disorders in users. The method includes: acquiring user sleep target information; acquiring user physiological data collected in real time; determining the user's current sleep state information based on the user's physiological data; determining differential frequency audio information based on the user's current sleep state information and user sleep target information; generating a first audio signal and a second audio signal based on the differential frequency audio information, wherein the first audio signal and the second audio signal have a specific frequency difference; and sending the first audio signal and the second audio signal with the specific frequency difference to the user's left and right ears respectively, based on the first audio signal and the second audio signal. Through the output and dynamic adjustment of binaural differential frequency audio, sleep disorders are effectively improved, with strong safety and applicability.

The invention relates to the technical field of sleep regulation, and provides an intelligent sleep environment regulation system and method. The system comprises a main control module, a sleep sensing module, a sleep stage inference module, a lighting effect strategy generation module and a lighting effect execution module, wherein the sleep sensing module senses vital sign signals, temperature distribution information and space contour information in a monitoring area in a non-contact manner; the sleep stage inference module is used for performing fusion analysis on the multi-source heterogeneous data acquired by the sleep perception module and inferring the sleep stage of the user; the main control module generates different light control instructions based on different sleep stages, the lighting effect strategy generation module responds to the light control instructions and outputs lighting effect driving signals corresponding to the sleep stages, and the lighting effect execution module generates sleep adjustment lighting effects according to the lighting effect driving signals. According to the scheme, wearing discomfort and sleep interference are eliminated, and the defects that a single sensor is low in precision, poor in interference resistance and weak in scene understanding are overcome.

The invention belongs to the technical field of sleep regulation and control, and aims to provide a sleep regulation and control method and system based on closed-loop sound stimulation. Through phase tracking and phase compensation, the slow wave rising state can be accurately locked, millisecond-level synchronization of sound stimulation and brain slow wave oscillation can be achieved, compared with a traditional scheme only based on amplitude triggering, the physiological matching performance of sound stimulation can be remarkably improved, and the problem that stimulation and endogenous rhythm are not synchronous is fundamentally solved. According to the invention, slow wave phase locking can be realized, sound stimulation can be applied to a user at an optimal phase point, delay compensation capability is provided, and accurate control of sleep regulation can be realized.

The invention belongs to the technical field of smart home and health monitoring, and particularly relates to an intelligent sleep regulation system integrating light hypnosis and infrared-sound perception, which comprises a data acquisition module, an intelligent analysis processing module, an environment regulation and control system and a photocatalytic hypnosis module, according to the photocatalytic hypnosis device, the photocatalytic hypnosis module actively catalyzes and decomposes organic volatile matters in indoor air through a photocatalytic reaction device with a specific wavelength, and a specific-wavelength secondary light source capable of promoting natural synthesis of human body melatonin is generated in situ in the process. In the process, the multi-mode sensor collects physiological data and environment data of the user in real time, comprehensive analysis is conducted through the intelligent analysis processing module, environment parameters are dynamically adjusted, starting and stopping, intensity and spectrum output of the photocatalytic reaction can be accurately controlled, and active and non-intrusive adjustment of the circadian rhythm of the user is achieved. According to the invention, the crossing from environmental regulation to active physiological intervention is realized, and the sleep induction and maintenance effect is obviously improved.

The invention discloses a closed-loop sleep regulation and control head band device integrated with earlobe micro-electrical stimulation, and relates to the technical field of sleep regulation and control head bands, the closed-loop sleep regulation and control head band device comprises a head band main body, connecting rods, a sponge belt and a connecting mechanism, massage instruments are symmetrically arranged on the outer wall of the head band main body, and the connecting rods are symmetrically and fixedly connected to the outer wall of the head band main body; the end part of the connecting rod is fixedly connected with an earlobe stimulator, the sponge belt is arranged outside the head band main body, and a connecting mechanism is arranged inside the head band main body. By means of the arrangement mode that the sponge belt, the winding rod, the connecting belt, the positioning assembly and the clamping assembly are matched, the length of the connecting belt can be adjusted through the positioning assembly, the tightness degree can be freely set according to the head circumference of a user, the tightening feeling is eliminated, and the winding rod and the clamping assembly ensure that the connecting belt is stably released and wound; it is ensured that the electroencephalogram collection electrode and the earlobe stimulator do not deviate from a preset part, and the accuracy of physiological signal collection and the effectiveness of stimulation intervention are guaranteed.

This invention discloses a sleep regulation method and system, applicable to sleep regulation systems comprising a first terminal and a second terminal. The method includes: simultaneously outputting pulse signals through the second terminal and acquiring bioelectrical signals through the first terminal, determining an objective perception threshold based on time-locked analysis; acquiring historical regulation data to distinguish between novice adaptation mode and mature treatment mode; in novice adaptation mode, limiting the upper limit of output intensity based on the objective perception threshold, controlling intensity ramping through physiological relaxation state feedback, and performing intensity rollback when pain features are detected; in mature treatment mode, generating an adaptive stimulation prescription based on a dual-state assessment of resting period electrical signals combined with a general threshold and an individual historical baseline, and dynamically adjusting the output intensity according to real-time bioelectrical signals during the output process.

The invention relates to the technical field of sleep regulation and control, and aims to provide a psychological and physiological relay type sleep regulation and control system based on a sleep phase change critical point, so as to solve the problems that in the prior art, psychological guidance and physical intervention are separated, and the intervention opportunity faces state adaptation and detection lag, and improve the sleep regulation and control efficiency. The technical scheme can be summarized as follows: a processing module starts an electroencephalogram scanning module after being electrified and started, starts and keeps a user state judgment module after being started for a first time, starts a digital cognitive behavior therapy module if a judgment result is a high wake-up state, and starts a neuron avalanche phase change monitoring module if the judgment result is not the high wake-up state; after the neuron avalanche phase change monitoring module is started, multi-channel electroencephalogram scanning of a user is monitored according to a preset neuron avalanche phase change monitoring algorithm, and whether the time interference stimulation module needs to be started or not is judged according to a monitoring result. The method solves the problem of separation between psychological guidance and physical intervention, and is suitable for sleep regulation and control.

The present application relates to the technical field of nursing, solves the problem that the millimeter wave radar sleep monitoring parameter is fixed, lacks personalized learning and large model fusion in the prior art, which leads to difficulty in accurately detecting sleep posture and evaluating sleep quality, and provides a sleep regulation method, device and equipment fusing millimeter wave radar and a large model. The method comprises the following steps: inputting basic information and sleep data of a target object into a neural network model, obtaining millimeter wave radar signals output by the adjusted millimeter wave radar and nursing environment data according to obtained personalized modeling data; performing feature extraction on the preprocessed millimeter wave radar signals to obtain breathing profile amplitude features and radar point cloud micro-motion features, and inputting the features and the nursing environment data into a large model, and generating sleep regulation suggestions for the target object according to generated sleep posture detection results and sleep quality evaluation results. The present application improves the accuracy of sleep posture detection and sleep quality evaluation for different groups of people.

This application discloses a sleep regulation method and device using multimodal sensor data closed-loop VNS technology, belonging to the field of wearable device technology. By real-time acquisition of multimodal physiological signals, it dynamically estimates endogenous sleep dynamic variables such as sleep homeostasis pressure, synaptic homeostasis level, and sleep recovery rate. Combined with future phase window prediction of super-diurnal rhythms, it can accurately perceive the user's real-time sleep recovery needs. Therefore, the generated stimulation commands are closely linked to the user's own sleep recovery process, achieving timely and personalized sleep regulation, overcoming the limitations of related technologies such as delayed regulation timing, lack of intrinsic correlation, and inability to perceive in real time.

The present application belongs to the field of traditional Chinese medicine, and relates to medical uses of Sishen pills or extracts thereof. Specifically, any one selected from items (1)-(3) below in the preparation of a drug for sedative-hypnotic, treatment or prevention of insomnia, anti-anxiety, or sleep regulation: (1) a pharmaceutical composition comprising Myristicae Semen, Fructus Psoraleae, Schisandra chinensis, Evodia rutaecarpa, Fructus Jujubae, and Zingiber officinale; (2) an extract which is a water extract and / or an ethanol extract of the pharmaceutical composition in item (1); and (3) a pharmaceutical preparation comprising the extract in item (2) and one or more pharmaceutically acceptable excipients. The pharmaceutical composition, extract or pharmaceutical preparation described in the present application has good sedative-hypnotic, prophylactic or therapeutic effects on insomnia, or sleep regulation.

The invention discloses an intelligent head-mounted device for sleep improvement in the technical field of sleep-aiding physiotherapy, and the device comprises a flexible patch group which is used for being attached to the skin surface of the head of a user; the flexible patch set comprises a pillow area flexible patch, a forehead area flexible patch and bilateral temporal area flexible patches, wherein the forehead area flexible patch and the bilateral temporal area flexible patches are symmetrically arranged. The pillow area flexible patch is used for providing stable support when a user lies on the back and stimulating a visual cortex and an afterbrain area related to sleep regulation; each flexible patch comprises a self-adaptive interface layer, a substrate layer, a multi-mode stimulation module, a physiological signal sensor and a control module which are laid from bottom to top. The problems of wearing compression and displacement in sleep are solved through the distributed flexible patch and the self-adaptive interface layer, the sleeping efficiency and the sleeping depth are remarkably improved, and individuation and self-adaptive optimization of intervention parameters are achieved; and finally, sleep improvement experience integrating extreme comfort, efficient intervention, stability, reliability and continuous intelligent evolution is provided for the user.

The invention provides a multi-mode closed-loop sleep regulation and control system and method and a sleep-aiding eyeshade, and the system comprises a data collection module which is used for continuously collecting a single-channel forehead electroencephalogram signal and a body movement signal; the data processing module is used for identifying the current sleep stage of the user and dynamically adjusting a multi-modal intervention strategy; the multi-modal execution module is provided with execution units with multiple modals, and is used for acquiring the multi-modal intervention strategy and controlling the execution units to perform sleep intervention on the user according to the multi-modal intervention strategy; and the safety module is used for guaranteeing the safety in the sleep intervention process. According to the method, a complete closed-loop system for accurately collecting physiological signals, dynamically recognizing the sleep state, cooperatively scheduling multi-mode intervention and perfecting safety guarantee is constructed, so that the whole process optimization from accurate sensing of the sleep state to dynamic adaptation of an intervention strategy is realized; and the multi-modal intervention strategy is matched with the sleep state of the user in real time and is individually matched with the sleep habit of the user, so that the regulation and control accuracy and effectiveness are greatly improved.

This invention provides a sleep regulation method and system based on dynamic fit and collaborative rotation control, belonging to the field of smart home technology. The invention utilizes a macroscopic rotating skeletal device to slowly and continuously adjust the body's positional angle on the supporting platform, enabling the weight-bearing parts of the body to shift over time. A microscopic adaptive fit device dynamically compensates for local support height, ensuring continuous fit during rotation and reducing shear force and friction. Through multimodal perception and stage discrimination, intervention is performed only during the most suitable sleep stage, reducing the risk of awakening due to control actions. By introducing a graph structure spatiotemporal completion model, specific optimization is performed for scenarios with missing pressure data, restoring the usable pressure field and maintaining the effectiveness of subsequent control links. This solves the technical problems of insufficient static support, significant shear discomfort during rotation, and unstable control in scenarios with missing pressure data in existing technologies.

The present application relates to a kind of intelligent sleep regulation method and system based on closed-loop acoustooptic brain wave entrainment, real-time acquisition and preprocessing electroencephalogram (EEG) by wireless dry electrode, high-precision sleep staging is realized using deep learning model.The system uses fuzzy PID controller to dynamically adjust acoustooptic synergistic stimulation: acoustic module generates binaural beat signal, optical module outputs blue light (470nm) and amber light (590nm) pulse, through phase synchronization (phase difference ≤10°) and golden section frequency coupling (f_L=1.618f_A) to enhance brain wave entrainment efficiency.Closed-loop feedback updates parameters every 30 seconds, adjusts sound pressure level (30-50dB) and light intensity (10-100lux) according to Weber-Fechner law, response delay <200ms.Three-level safety mechanism monitors gamma wave anomaly, epileptiform discharge and impedance overrun in real time, triggers graded protection (alarm, cut off light stimulation, shutdown).Clinical verification shows that the success rate of delta wave and theta wave entrainment is 71% and 68% respectively, and the sleep improvement effect is good, providing a safe and efficient intervention scheme for sleep disorders.

The invention relates to a preparation method and application of a melatonin analogue, the melatonin analogue has a structure as shown in a formula I. The melatonin analogue can play a role more stably and enduringly in a central nervous system after nasal administration, and has the effects of promoting cell proliferation, resisting oxidation and regulating sleep.

The utility model provides a sleep regulation system, which relates to the technical field of sleep regulation, and comprises a wearable monitoring and processing device, which is used for monitoring and processing a photoelectric volume pulse wave signal of a user in advance to obtain corresponding early warning information; the sleep signal acquisition equipment is used for acquiring electroencephalogram signal data when the user sleeps; the information processing terminal is connected with the wearable monitoring and processing equipment and the sleep signal acquisition equipment, and is used for receiving the early warning information and processing the electroencephalogram signal, the acceleration signal and the early warning information to obtain a corresponding processing result; the sleep adjusting device is connected with the information processing terminal and used for completing sleep adjustment according to the processing result; the sleep quality of a user with sleep rhythm disorder can be improved in a personalized manner.

The application belongs to the technical field of human brain electrical signal processing and brain regulation, and provides a multi-modal coupling type closed-loop electric stimulation sleep cooperative signal regulation device and system, which acquires multi-modal physiological signals including EEG slow wave power, cerebral blood flow and cerebrospinal fluid flow signals, filters and pre-processes the acquired multi-modal physiological signals to obtain pre-processed multi-modal signals, calculates the time domain correlation of the EEG slow wave power and the cerebral blood flow, and the frequency domain coherence of the cerebral blood flow and the cerebrospinal fluid flow signals, introduces the regulation factor of the time domain correlation of the EEG slow wave power and the cerebral blood flow and the frequency domain coherence of the cerebral blood flow and the cerebrospinal fluid flow signals to obtain a signal stimulation intensity calculation formula, and combines the signal stimulation intensity calculation formula and a constructed double-layer optimization architecture to optimize the signal stimulation intensity to obtain optimized signal stimulation intensity. A precise sleep regulation signal is generated.

The invention discloses a preparation method of an efficient sleep regulator. According to the method, intermediate-state impurities are accurately controlled, so that the generation of the impurities is effectively inhibited, and the burden in the subsequent product refining process is remarkably reduced, thereby ensuring that a high-purity target product can be stably produced, and meanwhile, the high yield of the product is realized by comprehensively improving the preparation steps.

This utility model relates to a clear vision sleep-regulating lens and glasses. The lens includes a substrate. The side of the lens closest to the glasses when worn is defined as the inner side. The inner surface of the substrate has an anti-reflective film layer, which is composed of sequentially stacked silicon oxide and titanium oxide layers, wherein the silicon oxide layer is connected to the inner surface of the substrate. The outer surface of the substrate has a light-regulating layer, which is composed of sequentially stacked silicon oxide and zirconium oxide layers, wherein the silicon oxide layer is connected to the outer surface of the substrate. The lens and glasses can promote the brain to generate sleep signals, while providing clear vision and a good user experience, showing excellent application prospects.

The application belongs to the technical field of bioactive peptides and polypeptide engineering, and specifically discloses a novel sleep-regulating nonapeptide isolated from Symplectoteuthis oualaniensis and a targeted enzymatic preparation method thereof, and the primary structure sequence of the nonapeptide is Trp-Ala-Gly-Gly-Asn-Ala-Ser-Gly-Lys (WAGGNASGK). The application uses the protein isolated from the body wall of Symplectoteuthis oualaniensis as raw material, and sequentially adopts protease from thermophilic bacteria and trypsin for directional double-enzyme hydrolysis, and the target nonapeptide is efficiently obtained through membrane filtration and chromatography purification. The target nonapeptide has the effects of promoting the production of gamma-aminobutyric acid by astrocytes and promoting the synthesis of 5-hydroxytryptamine by human neuroblasts, and has application value in regulating sleep and improving sleep disorders.