The invention discloses a wearable weariness detection and intervention system. The wearable weariness detection and intervention system comprises a dressing device body, an image collecting module for collecting the eye movement data of a wearer, an infrared lighting source, a head movement data collecting module for collecting the head movement data of the wearer, a waking promoting module and acore treatment module, wherein the waking promoting module comprises a light stimulating unit, a sound stimulation unit and a shaking stimulation unit; and the core treatment module comprises an eyemovement data analyzing module, a head movement data analyzing module, a fatigue degree analyzing module and a control module. According to the wearable weariness detection and intervention system, through integrated assessment of eye movement and head movement information, the fatigue degree of human bodies can be decided intelligently, and according to the fatigue grade of the human bodies, prewarning is performed; and waking promotion stimulation is performed in a sound, light and vibration combination manner, so that the fatigue degree of the human bodies is reduced, and the warning degreeand the operation capacity are increased. Based on a human eye blinking analyzing algorithm of plus and gradients, data analysis is performed, and the blinking state judging robustness, disturbance resistance and the efficiency can be improved.