41 results about "SOUND STIMULATION" patented technology

The invention discloses an acoustic stimulation nerve regulation and control service management system combining AI and big data analysis, and the system comprises a cloud center layer, a region edge layer, a doctor management layer and a patient terminal layer which are connected with one another, the cloud is provided with a client management module, and an exclusive account is established for each patient; and an individualized sound stimulation scheme is generated and dynamically optimized by using an AI algorithm to realize remote closed-loop regulation and control. The platform supports remote demonstration and teaching of experts, autonomous operation and maintenance of clients and a mutual assistance network of the experts, and a cloud-side-end collaborative AIoT intelligent system is formed. The system is provided with a national-level data supervision interface, so that safety and controllability are ensured. Through the above mode, the AI and big data analysis combined acoustic stimulation nerve regulation and control service management system improves the accuracy and efficiency of personalized scheme formulation and optimization by constructing a collection-analysis-decision-execution-feedback-optimization closed-loop process; therefore, cloud-edge-end-human collaborative closed-loop intelligent regulation and control management with individualized nerve regulation and control and compliance safety considered is formed.

The application is based on a multi-channel brain electrical signal acquisition system of auditory evoked potential: after receiving the brain electrical signal acquisition instruction through the communication circuit, the control circuit controls to send a trigger signal to the audio generation circuit, and the audio generation circuit generates an audio signal based on the audio source obtained through the audio source interface; the audio driving circuit generates an audio driving signal containing the audio signal based on the audio signal, and the control circuit controls the audio driving circuit to output the audio driving signal of the set time length through the earphone interface, so that the earphone outputs the sound stimulation to act on the collector; the audio driving circuit generates a synchronization signal based on the audio driving signal and transmits it to the signal acquisition circuit, and the signal acquisition circuit acquires the multi-channel brain electrical signals of multiple brain electrical electrodes through the signal acquisition interface and transmits the multi-channel brain electrical signals to the control circuit; the control circuit stores the multi-channel brain electrical signals in the storage circuit and uploads them to the upper computer through the communication circuit; the control circuit controls the system operation indication circuit to light up when the system operates normally.

The application provides a sound stimulation-brain electrical response closed-loop analysis system and method, relates to the technical field of brain electrical data analysis, and comprises the following steps: obtaining real-time brain electrical data under sound stimulation based on a standardized interface, and performing artifact removal and data standardization operations to obtain standard brain electrical data; performing response latency analysis on the standard brain electrical data to obtain response latency data; performing response significance analysis on the standard brain electrical data to obtain response significance data; extracting an abnormal response event set from the standard brain electrical data, and performing context feature modeling and abnormal root cause analysis on the abnormal response event set based on the response latency data and the response significance data to obtain abnormal root cause data; and generating a brain electrical response analysis graph interface corresponding to the response latency data, the response significance data and the abnormal root cause data based on neural signal analysis logic, and visually displaying the brain electrical response analysis graph interface.

The application discloses a real-time sound feedback method and equipment based on gait event triggering and belongs to the field of walking cognitive experiment equipment. The equipment comprises a sensing unit, a lower computer, an upper computer and a sound conveying system; the sensing unit comprises a pressure sensor installed in a shoe cover and dispersedly transmitting pressure by a hard foam pad, the heel of a subject rhythmically presses the hard foam pad during walking, and the sensing area of the pressure sensor and the protective film are kept in a detachable pressure contact during the heel strike; the lower computer collects the voltage signal output by the pressure sensor in real time, maps the voltage signal into a standard pressure value and then transmits the standard pressure value to the upper computer in real time, the upper computer analyzes the standard pressure data stream, and when it is determined that the heel strike event occurs, the upper computer immediately controls the sound conveying system to emit sound stimulation with a preset frequency, amplitude and time length. The application provides a multimodal platform interconnection and closed-loop system integration scheme and can provide support for psychology and cognitive neuroscience research.

The utility model discloses a fingertip decompression toy which comprises a base plate, a ring portion and a protruding portion. Wherein the two ends of the finger ring part are connected with the lower surface of the base plate respectively, and the finger ring part and part of the lower surface of the base plate form an annular shape used for being arranged on a finger in a sleeving mode; the lower surface of the base plate is further provided with a groove, and the groove extends towards the upper surface of the base plate and forms the protruding part higher than the upper surface of the base plate. The protruding parts are made of elastic materials. The technical scheme provided by the utility model is small and exquisite in structure and convenient to carry, can be flexibly worn on different fingers, can adjust the attached sound effect when the lug boss is shifted by flexibly setting the sizes of the groove and the lug boss, and provides rich sound stimulation.

The utility model relates to the technical field of bird hearing perception system research, concretely relates to a bird brain stereoscopic positioning device, is applicable to small and medium size birds, including bottom plate, ear canal positioner, bill angle positioner and bill mouth positioner, the stand is set up on the bottom plate, the ear lever is fixed on the cross arm of stand, the ear canal positioner includes the left and right two parallel setting stands, left and right two ear levers, the stand is in the shape of " " the ear lever includes inner ear lever, outside sleeve lever, top cone and fastening screw, outside sleeve lever can along inner ear lever and carry out the translational sliding, and the position is fixed through fastening screw, the bill angle positioner includes side plate, bill lever and locking screw, the bill mouth positioner includes base, positioning stand, bill mouth positioning head, compression ring, the base can slide horizontally, the utility model has reduced the ear canal blockage and the phenomenon of weak support because of traditional embedded ear lever and single side bill lever, greatly improves the listening range and effect of bird hearing perception system to sound stimulation.

This invention discloses a hearing screening and tinnitus assessment method based on multi-frequency cross-analysis, specifically relating to the fields of hearing testing and neural information processing technology. It constructs an initial hearing vector in the individual frequency domain, generates a deviation feature vector based on a standard population database, extracts a set of abnormal frequency bands, and constructs a frequency domain focusing model. Multiple-intensity sound stimulation is applied to the abnormal frequency bands, and neural response parameter sequences are collected. Further cross-spectral analysis is performed to construct an individualized tinnitus resonance map, and the dominant frequency features and response intensity are extracted. Combined with subjective tinnitus scores, a tinnitus risk index is calculated, and a screening conclusion is output. This invention can achieve objective, quantitative, and spectral-level tinnitus identification, improving screening accuracy and clinical applicability.

The invention discloses a hearing aid and rhythm sound stimulation device based on dual-channel fusion and a control method, and the device comprises a microphone array, an analog-to-digital conversion module, a Bluetooth receiving module, an audio switching and sampling rate conversion module (ASRC), a digital signal processor (DSP), a power amplification module, and a central control unit. A Bluetooth acoustic stimulation signal injection channel is arranged between a microphone input of the hearing aid and a DSP (digital signal processor), and is divided into two paths through ASRC: one path is a Bypass Path, and a Bluetooth acoustic stimulation signal is directly output to a programmable gain amplification and amplitude limiting module and a power amplifier module; and the other path is a DSP fusion path, and the Bluetooth acoustic stimulation signal and the microphone signal are subjected to weighted fusion in the DSP. According to the hearing aid and rhythm sound stimulation device based on dual-channel fusion and the control method, a hardware-level dual-channel structure and an AI self-adaptive control algorithm are introduced into a hearing aid system, low-delay, high-fidelity and multi-mode switchable hearing compensation and nerve regulation are achieved, and the hearing aid and rhythm sound stimulation device has the low-delay (lt, 3ms), high-fidelity and multi-mode intelligent switching capacity.

A muscle strength improvement device 1 is disclosed that generates a sound stimulus to improve muscle strength. The frequency of the sound stimulus changes over time.

The invention discloses a plant acousto-optic synergistic growth promotion control device, and relates to the technical field of hybrid intelligent automatic control, the device comprises a spectrum driving module, a photoperiod controller, an acoustic execution array, a sensing acquisition module and a calculation and control module electrically connected with the above modules; the calculation and control module is configured to execute a cooperative growth promotion control flow. Phase coupling of acoustic stimulation and spectrum regulation and control is achieved in the same system, a low-peak-value multi-tone detection sequence based on blue noise Poisson disc sampling and Schroeder multi-tone phase distribution is established, and a directional sound field is generated through combined solution of a multi-channel cross-spectrum square matrix and a directional vector table. And a phase reset sequence with the minimum duration is formed by combining a phase response curve mapping table matched with the crop growth rhythm, so that the sound stimulation and the spectrum formula are synchronized in the time domain and the phase.

The application discloses a non-invasive human sleep nerve regulation method and system. The method comprises the following steps: acquiring a first physiological signal of a user, performing real-time sleep staging on the user to determine a deep sleep stage of the user; based on the result of the sleep staging, detecting slow wave power through a second physiological signal when the user is in the deep sleep state; calculating a phase angle of the slow wave according to the slow wave state, so as to perform tACS electric stimulation when the phase angle meets a preset condition; after a period of tACS electric stimulation, acquiring a third physiological signal of the user, and acquiring a physiological active state of the user by analyzing the third physiological signal; and when the physiological active state is an uplink state, performing TMR sound stimulation. Thus, through mutual cooperation of the tACS electric stimulation and the TMR sound stimulation, non-invasive nerve regulation is realized on the user, and the nerve regulation effect on sleep is improved.

The utility model discloses a mouse cage with a muscle strength testing function, which relates to the technical field of muscle strength testing and comprises a rat and mouse holding power instrument, a control panel is arranged on the outer surface of the rat and mouse holding power instrument, and a connecting rod is mounted at the connecting end of the rat and mouse holding power instrument. And an auxiliary mechanism connected with the connecting rod is arranged at the upper part of the rat and mouse holding power instrument. By means of mutual cooperation of the adjusting assembly, the luring assembly and the stimulating assembly, activity space of rats and mice can be conveniently adjusted according to requirements, food is stored in the luring assembly to luring the mice to move forwards, and if the mice run backwards without being attracted by the food, the mice can be attracted to move forwards. When the mouse is used for mouse muscle force testing, current stimulation is carried out on the buttocks of the mouse through the stimulation assembly under the condition that the life safety of the mouse is not harmed, meanwhile, strong light and sound stimulation is carried out on the mouse, the mouse is promoted to move forwards, an experimenter pulls the tail of the mouse, and the device is only used for mouse muscle force testing experiments.

The embodiment of the present disclosure provides a non-invasive brain-computer interface system based on earphone real-time electroencephalogram monitoring-auditory stimulation, and relates to the technical field of neural engineering. The system comprises an in-ear earphone device and an external control device. The in-ear earphone device is used for collecting the brain wave signals of a user, transmitting the brain wave signals to the external control device, generating a sound stimulation signal based on a sound stimulation trigger instruction, and delivering the sound stimulation signal to the ear of the user for sound stimulation. The external control device is used for detecting whether there is a characteristic sharp-slow wave signal corresponding to absence epilepsy attack in the brain wave signals. When the characteristic sharp-slow wave signal corresponding to the absence epilepsy attack is detected, the target sharp-slow wave of the brain wave signals is extracted, a sound stimulation trigger instruction is generated based on the sharp wave component of the target sharp-slow wave, and the stimulation trigger instruction is transmitted to the in-ear earphone device. Real-time and accurate monitoring and non-invasive closed-loop intervention of absence epilepsy attack can be realized, the system has high safety, and is portable and comfortable.

The invention discloses an ear vagus nerve acoustoelectric dual stimulation system and method, and relates to the technical field of nerve stimulation medical treatment. The objective of the invention is to solve the technical problems of limited autonomic nerve regulation effect, insufficient cardiovascular disease prevention and treatment efficiency, easy generation of nerve adaptation due to long-term stimulation, poor regulation and control precision and the like in the existing ear vagus nerve single electrical stimulation mode. The system comprises an electrical stimulation module, a sound stimulation module, a control module, an electrode, a sound stimulation probe, a power supply module and a parameter input module, the control module cooperatively regulates and controls all the modules, and the electrodes and the sound stimulation probe output electrical stimulation and sound stimulation respectively. According to the method, acoustic-electric dual synergistic stimulation of the ear vagus nerves is realized by cooperatively regulating and controlling stimulation parameters. The acousto-electric synergistic interaction is utilized, the autonomic nerve regulation and control ability is enhanced, the physiological index regulation precision is improved, related cardiovascular diseases are effectively prevented and treated, the advantages of being high in safety, wide in adaptability, stable in regulation, convenient and fast to operate and capable of being used for a long time are achieved, and the method can be applied to clinical prevention and treatment, rehabilitation treatment and family health management scenes.

The present application provides an electroencephalogram sound stimulation evaluation prediction and adaptive output method and system, which is based on an individual-group bidirectional migration collaborative mechanism of shared feature space and distribution alignment constraint to fuse individual specificity and group commonality knowledge, forming a mechanism to overcome the individual differences of electroencephalogram; the method also uses an adaptive decision fusion mechanism based on prediction uncertainty evaluation to ensure output stability when the prediction model reliability fluctuates, and a model dynamic online updating mechanism based on concept drift detection to adapt the prediction model to the long-term changes of the user state, forming a mechanism to improve accuracy and robustness; the present application can effectively overcome the individual differences of electroencephalogram, realize high-precision system prediction and output, and has robustness.

The invention relates to the field of multi-mode resonance, in particular to a target object data acquisition system based on photoacoustic magnetic vibration wave resonance, and the system comprises a data acquisition module which is used for obtaining neural response data when a target object receives single stimulation; the nerve response relation generation module is used for acquiring a nerve response relation stimulated by the opto-acoustic magnetic vibration waves; the mismatch result generation module is used for calculating a starting time mismatch component, a stimulation intensity mismatch component and a continuous coverage mismatch component of the photoacoustic magnetic vibration wave stimulation to form a mismatch result of the photoacoustic magnetic vibration wave stimulation; the differential compensation control parameter set generation module is used for generating a differential compensation control parameter set; and the multi-mode collaborative stimulation output module is used for performing collaborative control on light stimulation, sound stimulation, magnetic stimulation and mechanical vibration stimulation to form light-sound-magnetic vibration wave resonance stimulation. According to the system, effective resonance of different stimuli is realized, and the collaborative perception ability and nerve response stability of a target object to multi-modal stimuli are enhanced.

The invention belongs to the technical field of sleep regulation and control, and aims to provide a sleep regulation and control method and system based on closed-loop sound stimulation. Through phase tracking and phase compensation, the slow wave rising state can be accurately locked, millisecond-level synchronization of sound stimulation and brain slow wave oscillation can be achieved, compared with a traditional scheme only based on amplitude triggering, the physiological matching performance of sound stimulation can be remarkably improved, and the problem that stimulation and endogenous rhythm are not synchronous is fundamentally solved. According to the invention, slow wave phase locking can be realized, sound stimulation can be applied to a user at an optimal phase point, delay compensation capability is provided, and accurate control of sleep regulation can be realized.

The invention belongs to the field of multi-brain-region transcranial magnetic stimulation equipment, and particularly relates to foldable multi-brain-region transcranial magnetic stimulation equipment and an anti-interference method thereof.The multi-brain-region transcranial magnetic stimulation equipment comprises an upper cover and a lower cover and further comprises a folding mechanism used for connecting the upper cover and the lower cover; a TMS coil, a binaural beat loudspeaker module and an operation interface are integrated in the upper cover, the TMS coil is fixedly installed in the center area of an inner cavity of the upper cover, and the TMS coil is used for generating a focusing magnetic field penetrating through the skull. The double design of spatial separation and independent shielding is adopted, it is ensured that audio signals transmitted to the binaural beat loudspeaker module are pure and free of noise, clear and stable binaural beat sound stimulation is output, and the spatial position of the TMS coil is adjustable relative to the head of a user.

The wearable electroencephalogram monitoring device comprises an electroencephalogram cap, an earphone and an electroencephalogram collecting device, a plurality of electroencephalogram electrodes are arranged on the electroencephalogram cap, and the electroencephalogram collecting device is installed on the electroencephalogram cap and comprises a shell. A power supply interface, a power supply circuit, a sound source interface, an audio generation circuit, an audio drive circuit, an earphone interface, a signal acquisition interface, a signal acquisition circuit, a control circuit, a storage circuit, an operation indication circuit and a communication circuit are integrated in the shell; the electroencephalogram acquisition assembly and the sound stimulation assembly are integrated to form the electroencephalogram acquisition device, the electroencephalogram stimulation device is installed on the electroencephalogram cap, generation of sound stimulation and acquisition of signals are facilitated, occupied space is small, the electroencephalogram acquisition device is neat and orderly, circuits in the electroencephalogram acquisition device are optimally designed, and the electroencephalogram acquisition device is convenient to use. And multi-channel electroencephalogram signals can be collected more accurately.

Timer comprising a sound generator, at least one sound-stimulating element, a drive and a disk moved by it, wherein the moving disk has at least one detent surface for temporarily holding the at least one sound-stimulating element in position, wherein the timer has at least one deflection element relative to which the disk moves, such that the deflection element exerts a force on the at least one sound-stimulating element at a certain time, which sets the sound-stimulating element in motion towards the sound generator and finally causes it to sound.

The utility model discloses a kind of sound-light adjusting devices based on neural oscillation, comprising: wearing component, it is adapted to the head of human body to be used for covering the head;Sound stimulation module, it is attached to the left and right sides of the wearing component to be used to with the ear of human body opposite and be attached to the ear, the sound stimulation module is used to sound to ear;Laser stimulation module, it is configured to the front side of the head to be used to emit laser to forehead area of head;Control module, it is attached to the back side of the wearing component, so as to be located at the back side of the head.The adjusting device integrates sound stimulation module, laser stimulation module and visible light stimulation module (such as, light lens barrel with visible light panel built-in) on wearing component, so that after wearing on the head, it can simultaneously realize sound stimulation, laser stimulation and visible light stimulation to brain.

The application discloses a sound stimulation self-adaptive regulation system based on abnormal state identification, wherein a signal acquisition and calculation module calculates an anxiety index by acquiring various physiological and motion sensing data of a user in real time; a panic identification and alarm module first corrects a motion state according to the motion sensing data, then runs a rapid threshold path and an unsupervised model path in parallel, and outputs a panic attack alarm signal and an abnormal intensity score; a sound stimulation control module selects a sound stimulation mode according to the output of the panic identification and alarm module and the anxiety index, and outputs corresponding sound stimulation according to an individualized file of the user; and a parameter optimization learning module evaluates the effect of sound stimulation in real time during the stimulation intervention process of the sound stimulation control module each time, optimizes stimulation parameters in the next step, and files and learns whole-process data after the intervention ends. According to the application, early and accurate identification and timely intervention of a panic attack state can be realized.

A vestibular function improvement device 1 for generating a sound stimulus to improve the vestibular function of the inner ear, wherein the frequency of the sound stimulus changes over time.

The present invention relates to a method for generating a sound stimulus for adjusting breathing rhythm, and an apparatus therefor. More specifically, the present invention relates to a method and an apparatus therefor, the method comprising: generating, on the basis of acquired breathing data when breathing data of a user is acquired from a breathing data acquisition device, a sound stimulus capable of guiding the breathing rhythm of the user and transmitting same to the user; and continuously acquiring breathing data through the breathing data acquisition device so as to adjust the generated sound stimulus on the basis of subsequently acquired breathing data.

The invention discloses an emotion auxiliary regulation system and method based on binaural rhythm and tactile vibration, and relates to the technical field of emotion regulation, the system comprises a biological feature recognition module, a sound stimulation module, a tactile vibration module, a control and processing unit and a user interaction interface; according to the invention, the biological feature recognition module collects the physiological and biological features of the user and accurately recognizes the emotional state, achieves the personalized adaptation of adjustment parameters, achieves the cooperative adjustment effect through the multi-mode stimulation mode integrating the binaural rhythm and the tactile vibration, improves the effectiveness of emotion adjustment, makes up for the defects of a single stimulation mode, and improves the user experience. By simplifying a user interaction interface and an automatic adjustment process, reducing operation complexity and meeting daily popularization and use requirements, and by storing biological characteristic data and adjustment records and establishing a scientific effect tracking mechanism, data support is provided for accurate emotion intervention, and finally an efficient, personalized, convenient and scientific emotion auxiliary adjustment effect is achieved.

This invention relates to the fields of regenerative medicine and neuromodulation technology, specifically disclosing the application of mediators that inhibit the activity of the auditory cortex in the preparation of drugs or intervention devices for promoting cartilage regeneration, repairing cartilage damage, and delaying or treating osteoarthritis. This invention promotes cartilage damage repair and osteoarthritis treatment by modulating the auditory cortex of the auditory center, providing two technical means: a chemogenetic method involving targeted injection of a viral vector carrying an artificial inhibitory receptor into the auditory cortex followed by administration of a DREADD agonist; and a sound stimulation method involving outputting sound stimulation to the individual at a level 5 dB higher than the ambient background noise. Animal experiments have confirmed that both methods can upregulate the expression of cartilage synthesis markers Col2, Acan, and PRG4, downregulate the expression of degradation markers Col1 and Mmp13, improve histological scores, and alleviate pain. This invention also provides an intervention device, including a sound insulation unit, a sound acquisition unit, a control unit, and a sound output unit. This device has the advantages of being non-invasive, easy to operate, and highly safe, providing an innovative strategy for cartilage regeneration and osteoarthritis treatment.

This invention provides a sleep intervention method, system, terminal device, and storage medium based on joint features. The method includes: extracting features from real-time respiratory signals to obtain respiratory rhythm stability features; extracting features from real-time electroencephalogram (EEG) signals to obtain slow-wave EEG features; synchronizing the respiratory rhythm stability features and the slow-wave EEG features in time, and inputting the obtained joint features into a first artificial intelligence algorithm model so that the model outputs a stimulation state judgment result for the user; when several consecutive stimulation state judgment results are all in a state that is pending confirmation of stimulation, inputting the collected real-time EEG signals into a second artificial intelligence algorithm model for signal analysis; when the analysis result is that the stimulation is possible, executing a sound stimulation task within a preset time delay; when the respiratory rhythm stability features or the slow-wave EEG features do not conform to a preset trend, ending the sound stimulation task. This invention can improve the convenience and accuracy of sleep intervention.

The application discloses a device for rapid recovery of body perception after anesthesia, which is used for helping patients recover body perception faster after operation. The device is composed of a temperature rising wrapping blanket, a pneumatic touching assembly, a micro vibration motor array and a sound stimulation assembly. The temperature rising wrapping blanket wraps the patient's body, uses graphene heating wires to create a warm environment and promotes blood circulation. The pneumatic touching assembly pumps air to the silica gel airbag through a micro air pump, so that the silica gel airbag intermittently touches the patient's body, and a flexible pressure sensor monitors the touching pressure. The micro vibration motor array vibrates at different frequencies and intensities, gently awakens the sensory nerves. The sound stimulation assembly plays sound through a Bluetooth sound box, activates the auditory nerves. The components work together, and the device can adjust the stimulation intensity according to the patient's recovery condition, realize the stimulation of the mode and adapt the recovery process, help the patient shorten the stay time in the PACU, improve the turnover rate and improve the postoperative experience.

The invention discloses a quick zebra fish abnormal behavior recognition system based on computer vision. A stimulation event stream is generated through a top strong light stimulation module and a vibration and sound stimulation module; obtaining high-quality zebra fish behavior image data; outputting the zebra fish three-dimensional track information and the zebra fish three-dimensional attitude parameters; forming a zebrafish behavior characterization feature set; encoding the zebra fish behavior characterization feature set, the stimulation event flow and the experimental protocol metadata into multichannel time sequence data according to a unified time axis; outputting a zebrafish behavior state sequence; generating a zebra fish abnormal behavior recognition result; output parameters of the top strong light stimulation module and the vibration and sound stimulation module are adjusted in real time, and stimulation-recognition-feedback closed-loop control is achieved. According to the invention, the defect that the existing NeRF or 2D skeleton is easy to lose lock and drift under complex optical conditions is obviously improved.

The invention relates to the technical field of medical equipment, in particular to a sleep regulation and control method, device and system and portable medical equipment. The method comprises the following steps: determining a sleep state of a user according to sleep wave feature data, heart rate feature data and motion feature data; determining a first initial stimulation parameter and a second initial stimulation parameter according to the sleep state; performing vagus nerve stimulation according to the first initial stimulation parameter, and performing sound stimulation according to the second initial stimulation parameter; when sleep wave feature data obtained after stimulation is executed is not in a first preset range, adjusting a first initial stimulation parameter and a second initial stimulation parameter; and repeatedly executing the steps of executing vagus nerve stimulation, executing sound stimulation and adjusting the first initial stimulation parameter and the second initial stimulation parameter until the sleep wave feature data obtained after stimulation is executed is within a first preset range. According to the method, the effectiveness of sleep regulation and control is remarkably improved.