135 results about "Dysphagia" patented technology

The invention belongs to the technical field of brain-computer interfaces, and particularly relates to a post-stroke dysphagia rehabilitation recognition system, feedback stimulation equipment and a storage medium. The system comprises a signal acquisition module, an electroencephalogram signal preprocessing module, a neural network feature extraction module, a statistical feature extraction module and a swallowing intention recognition module, and can recognize whether a patient has a swallowing intention or not through a Mama deep learning model based on space-time statistical features. The invention also constructs brain-computer interface equipment for rehabilitation of dysphagia after stroke in combination with electroencephalogram signal acquisition equipment and electrical stimulation equipment. The technical scheme of the invention has the advantages of being accurate in recognition, good in rehabilitation treatment effect and capable of forming center-periphery closed loop feedback, and has a very good application prospect.

The invention belongs to the field of food processing, and provides a preparation method of penaeus vannamei powder gel suitable for people with dysphagia, which comprises the following steps: taking penaeus vannamei meat, blending until no obvious particles exist, freezing, carrying out vacuum drying, powdering, sieving, mixing with water, fully hydrating to obtain a penaeus vannamei powder solution, adjusting the pH value of the penaeus vannamei powder solution to 9-11, stirring, adjusting the pH value to 6-8, and preparing the penaeus vannamei powder gel. And continuously stirring, adding carrageenan, heating and cooling to obtain the penaeus vannamei meal gel. The method disclosed by the invention is simple and easy to implement, and the pH migration treatment and the carrageenan treatment are utilized to generate a synergistic effect, so that the prepared penaeus vannamei powder gel meets the fifth-level standard of an IDDSI framework, and can meet the diet requirements of special crowds such as dysphagia patients on multiple aspects such as nutrition and texture.

The invention discloses a dysphagia rehabilitation training device which is characterized by comprising a base, a control panel, a water tank, a water pump and a training mechanism. The training mechanism comprises a plurality of electric push rods arranged in a lower cavity of an adjusting frame at equal intervals, a plurality of sleeves are arranged in an upper cavity of the adjusting frame at equal intervals, pistons are arranged at the output ends of the electric push rods and slidably mounted in the sleeves, and a supporting rod of an L-shaped structure is fixedly mounted at the top of the adjusting frame. A peristaltic pipe is arranged at the front end of the supporting rod, a stimulation ball is arranged at the front end of the peristaltic pipe, a plurality of air pipes are connected to the interior of the peristaltic pipe, the air pipes are slidably installed in the supporting rod, the tail ends of the air pipes are connected to the top of the sleeve, and a water outlet pipe and a water inlet pipe are arranged at the tail end of the stimulation ball; the water inlet pipe and the water outlet pipe are slidably mounted in the supporting rod; the device can guide the root of the tongue, stimulate the pharynx and train swallowing muscles at the same time.

The invention relates to the technical field of medical instruments, in particular to an ice stimulation training device for dysphagia rehabilitation, which comprises a box body with an upward opening, a cover plate arranged at the opening of the top of the box body, two partition plates arranged in an internal cavity at an interval up and down, and an auxiliary opening mechanism arranged in a training opening in the front side of the box body and used for opening the box body. An ice stimulation training head is arranged in the ice stimulation training device, the tail of the ice stimulation training head is connected with a control mechanism, and a pneumatic assembly is arranged on the left side of the top of the partition plate on the upper side and connected with the auxiliary opening mechanism through an air pressure rod assembly. The problems that in the prior art, an ice stimulation training device for rehabilitation of the stroke dysphagia generally can only achieve single ice stimulation treatment and lacks auxiliary taste stimulation and vibration stimulation for comprehensive treatment, so that the whole treatment process is long in time, more complex and free of cooperation, and the treatment cost is low are solved. Meanwhile, the compliance of the patient and the recognition degree of treatment are also reduced, and the patient cannot recover as soon as possible.

The invention provides a loxoprofen sodium double-release capsule micro-tablet and a preparation method of the loxoprofen sodium double-release capsule micro-tablet. Through the synergistic effect of the quick-release micro-tablet and the sustained-release micro-tablet, the quick-release micro-tablet can realize quick release and absorption, and the sustained-release micro-tablet can maintain relatively stable blood concentration for a long time. The administration frequency is reduced, the coordination of the postprandial administration requirement and the dietary habit is ensured, and the occurrence of gastrointestinal tract adverse reactions is reduced. The preparation provided by the invention conforms to the dosage form design of the hour pharmacology, can quickly take effect through administration twice every day, can maintain the blood concentration in the high-incidence time period of night diseases, avoids the disadvantage of taking medicine after meal when the night diseases attack, guarantees the sleep quality, and improves the overall treatment effect. The micro tablet is small in size and easy to swallow, and the medication compliance of patients with dysphagia is obviously improved. Through dosage form design and improvement, unmet clinical requirements are expected to be met by virtue of obvious advantages of the traditional Chinese medicine composition.

The invention provides a dysphagia screening system based on computer vision, and relates to the technical field of image recognition, and the system comprises an image collection module which collects image data of a swallowing event to obtain a time sequence image sequence; the motion field establishing module is used for extracting a motion point track sequence according to the time sequence image sequence and establishing a global motion transformation field; the motion separation module is used for carrying out registration correction on the global motion transformation field and carrying out motion separation on the stabilized image sequence to obtain local deformation components; the region segmentation module is used for carrying out key region segmentation on the local deformation components to obtain swallowing function parameters; and the risk identification module is used for identifying the obstacle risk of the swallowing function parameters and generating a swallowing obstacle screening report. According to the method and the device, the technical problem of relatively poor screening accuracy of the dysphagia based on the computer vision in the prior art can be solved, and the technical effect of improving the screening accuracy of the dysphagia based on the computer vision is achieved.

The invention discloses PSE-like chicken breast composite gel soft food suitable for people with dysphagia and a preparation method of the PSE-like chicken breast composite gel soft food, and belongs to the field of food processing. The raw materials of the composite gel soft food comprise PSE-like chicken breast, konjac glucomannan and a sodium chloride solution, and the preparation method comprises the following steps: adding a mixed solution of konjac glucomannan and sodium chloride into PSE-like chicken breast, stirring, carrying out heating treatment after uniform stirring, and then cooling to obtain the PSE-like chicken breast composite gel soft food. The prepared food is stable in total protein content, can effectively make up for insufficient intake of meat protein caused by limited feeding of people with dysphagia, and prevents malnutrition; the product texture meets the swallowing requirement, reaches the IDDSI level 5 or level 6 standard, can effectively reduce the risk of food residue and aspiration in the swallowing process, and has nutrition balance and food safety.

The invention provides a stroke dysphagia rehabilitation training interaction method and system, and relates to the technical field of wisdom medical treatment, and the method constructs a closed-loop and multi-dimensional rehabilitation interaction system through integrating four modules of swallowing function evaluation, course execution, psychological state monitoring and AR gamification training. A patient can complete structured evaluation of swallowing ability and a family support environment on a main interface in a one-stop mode, an adjustable personalized rehabilitation path is generated accordingly, and feedback is dynamically collected and executed in the training process to optimize course content; meanwhile, the emotion evaluation mechanism can timely identify negative psychological states and automatically trigger regulation intervention; by combining the augmented reality technology, food or tableware is recognized in real time in a real feeding scene, risk prompt and safety guidance are overlaid, the training interestingness and compliance are improved through interactive games, finally individuation, visualization, emotional and immersive fusion of the rehabilitation process is achieved, and the rehabilitation effect and life quality of stroke dysphagia patients are improved.

An oral liquid suspension comprising atomoxetine or a pharmaceutically acceptable salt thereof is disclosed, formulated at a concentration of about 20 mg / mL for the treatment of attention-deficit / hyperactivity disorder (ADHD). The suspension includes a dual preservative system (methylparaben and sodium benzoate), sweeteners, pH buffers, suspending agents, co-solvents, flavorants, and colorants. The composition demonstrates bioequivalence to Strattera® capsules, robust antimicrobial efficacy meeting USP <51> criteria, and physicochemical stability over 24 months in validated high-density polyethylene containers with child-resistant closures. The 20 mg / mL concentration enables precise dose titration for pediatric and dysphagic patients. Palatability is optimized through validated flavor masking studies, supporting high patient adherence. The invention further provides scalable manufacturing methods, quality control specifications, and methods of use for treating ADHD, offering a stable, safe, and patient-friendly alternative to solid oral dosage forms.

The application discloses a kind of simulation exercise devices for preventing dysphagia of cerebral apoplexy patient, it is related to cerebral apoplexy patient swallowing simulation technical field, including: placement bottom plate, adjustable dysphagia exercise mechanism and feedback analysis mechanism, adjustable dysphagia exercise mechanism is located in the right side of feedback analysis mechanism, adjustable dysphagia exercise mechanism: adjustable dysphagia exercise mechanism includes adjustable exercise component for swallowing mastication exercise intensity adjustment, by adjustable dysphagia exercise mechanism adjustable exercise component And the setting of flexible sensitivity promoting component, it is different from the function of rehabilitation training equipment in the prior art is relatively single, and the training device is replaced back and forth during rehabilitation training, and the linkage of training between devices cannot be guaranteed, effectively achieve when mastication training, patient lip and tongue are trained simultaneously with sensory force, close to life, effective simulation, better effect.

The utility model relates to the technical field of medical instruments, and discloses a dysphagia nursing out-call box which comprises a sealing assembly, a sealing part, a sealing door, a sliding frame, a rack and a gear, the sliding frame is fixed to one side of the sealing door, the rack is fixed to the bottom of the sliding frame, the gear is located on one side of the rack, and the sealing door is connected with the gear. The gear is meshed with the rack, the moving assembly is arranged on the gear and comprises a moving part, the moving part comprises a moving strip, a guide strip, a guide plate and a shifting plate, and the moving strip is located on one side of the gear. The box has the advantages that the box covers are arranged to be in the opening and closing type, when the box body needs to be completely opened, the two box covers can be simultaneously and oppositely opened, when small articles are taken, the box body can be half opened, the interior does not need to be completely exposed, large-area exposure is avoided, invasion of dust, bacteria, viruses and the like is reduced, the articles are kept in a sterile state, and the hidden danger of infection of patients is reduced.

The utility model discloses a pharyngeal electrical stimulation catheter which comprises a lengthened stomach tube and a catheter sleeve, the surface of the lengthened stomach tube is sleeved with the catheter sleeve, one end of the lengthened stomach tube is provided with a stomach tube reducing sleeve, the end, away from the stomach tube reducing sleeve, of the surface of the catheter sleeve is sleeved with a balloon, and the outer wall of the balloon is provided with a plurality of sets of electrode strips at equal intervals. And a plurality of groups of micro cameras are mounted on the surface of the balloon on one side of the electrode strip at equal intervals. The pharyngeal electrical stimulation catheter is convenient to operate, control and convey to the pharynx for accurate electric shock treatment, visual observation of operation electric shock is facilitated, direct observation of the implantation depth of the pharyngeal electrical stimulation catheter is facilitated, convenience of operation and use of the pharyngeal electrical stimulation catheter is improved, and the pharyngeal electrical stimulation catheter is used as a new treatment means and is worthy of popularization and application. New hope, simple instruments and equipment and operation procedures are brought to patients with dysphagia, so that the patients can be conveniently treated at home or in daily life, and a humanized treatment scheme is provided.

The application belongs to the technical field of dysphagia rehabilitation, and particularly relates to a cold stimulation device for dysphagia rehabilitation, which comprises a supporting column, a reciprocating electric telescopic rod coaxially and fixedly connected to one end of the supporting column, a semiconductor touch head fixedly connected to a telescopic end of the reciprocating electric telescopic rod, a biting seat fixedly connected to the supporting column, biting air bags fixedly and symmetrically connected to the biting seat, the biting air bags being communicated with the supporting column, and a detection tube fixedly connected to the biting seat. The oral cavity sealing mechanism automatically triggered by biting action can accurately detect the swallowing action according to the negative pressure of the oral cavity. After the effective swallowing action is detected, the stimulation can be paused through a delay start switch, the next round of training can be automatically started after the rest, and the timing and rhythm of each stimulation are ensured to be consistent with the physiological response. The normal exhalation can be realized while the oral cavity sealing space is formed, and the breathing safety is ensured.

A rehabilitation treatment device and method for a patient with swallowing dysfunction comprises a liquid bag (8) acting on the throat of the patient with swallowing dysfunction, a supporting frame (7) arranged on the liquid bag (8), a vertical beam (1) arranged on the supporting frame (7), and a fluid pump (91) arranged between the vertical beam (1) and the liquid bag (8). The upper end face of the liquid bag (8) is supported, expansion medium liquid is injected into the liquid bag (8) through the fluid pump (91), and external interference activity acting force is generated on the throat of a patient with swallowing dysfunction through the liquid bag (8). According to the swallowing-dysfunction patient rehabilitation device, slow expansion force generated by viscous liquid acts on the throat of a swallowing-dysfunction patient in the rehabilitation process, the technical problem that the throat of the patient is lifted up through the hands of a doctor is solved, and therefore the rehabilitation treatment effect of the swallowing-dysfunction patient is improved.

The utility model relates to the technical field of rehabilitation medical instruments, and discloses a dysphagia training aid which comprises a connecting column and a cooling rod, a fixing seat is arranged on the right side wall of the connecting column, and two supporting assemblies which are symmetrically distributed up and down are arranged in the fixing seat. And the right side walls of the two supporting assemblies extend to the right side of the fixing base, a connecting groove is formed in the fixing base, and a first limiting clamp is arranged on the left side wall of the connecting column. According to the dysphagia training device, by arranging the supporting assembly, firstly, a patient places the upper teeth on the top of an upper supporting plate and then places the lower teeth on the lower portion of a lower supporting plate, and at the moment, two threaded shafts are rotated, so that the upper supporting plate and the lower supporting plate move oppositely, and the upper teeth and the lower teeth are opened and supported; the cooling rod is prevented from being bitten and damaged, the practicability of the device is improved, and the device is convenient for a patient to use.

The invention discloses a flow velocity controllable throat stimulation device adaptive to a stroke dysphagia patient, and relates to the technical field of throat stimulation devices. The flow velocity controllable throat stimulation device adaptive to the stroke dysphagia patient comprises a host, an electrode patch, a pinhole swallowing patch, a conductive joint and an electrode wire which are arranged on a swallowing electrical stimulator body, the side wall of the conductive joint is fixedly sleeved with an annular cover, and a sliding ring is slidably connected in the annular cover. According to the flow velocity controllable throat stimulation device adaptive to the stroke dysphagia patient, the pinhole dysphagia paste around the electrode paste can be stricken, bubbles can be scraped and exhausted, negative pressure can be generated in the rotating cover, the rotating cover can be adsorbed on the skin under the action of the negative pressure, and the flow velocity controllable throat stimulation device is suitable for the stroke dysphagia patient. The pinhole swallowing paste has the advantages that the pinhole swallowing paste is better in pasting effect with the skin, the pinhole swallowing paste is more stable and reliable, the electrode paste is better in pasting effect with the skin, and the use effect is better.

Solid orodispersible compositions in the form of thin films for the oral administration of thyroid hormones are described, characterized by a high stability, and by the bioavailability of the active ingredient for oral absorption. The film compositions described are designed for rapid disintegration in the mouth, for sublingual administration, or to be held in the mouth for longer times before they disintegrate, but in any case without being mucoadhesive films. All the examples described are characterized by being thin and flexible and are suitable for administration even to patients who are not conscious, dysphagic or otherwise unable to swallow.

This invention provides a method and system for risk warning of dysphagia based on multi-signal analysis. The method includes: acquiring surface electromyography (EMG) signals, bioimpedance signals, laryngeal vibration signals, and neck microenvironment temperature and humidity signals from the wearer's neck using a flexible wearable sensing unit; using the respiratory phase determined by the neck microenvironment temperature and humidity signals as a time reference, performing time alignment and preprocessing on the multimodal physiological signals to obtain multi-channel time-series data; extracting and fusing features from the multi-channel time-series data to generate a discriminative fusion feature vector; inputting the vector into a pre-trained classification model for real-time inference to identify swallowing function states, including effective swallowing, ineffective swallowing, and suspected aspiration; and generating a graded risk warning signal in response to the identified abnormal states. This invention solves the problems of motion artifact interference and time alignment through multimodal signal fusion and respiratory rhythm calibration, achieving accurate and continuous monitoring of dysphagia risk.

An oral formulation of, or comprising, granules of active pharmaceutical ingredient(s), such as gepotidacin or a pharmaceutically acceptable salt thereof, which disperse rapidly in water are presented. The granules generate a palatable oral suspension in solution with good mouthfeel and are particularly useful for the paediatric or hard-of-swallowing patient population.

Disclosed are solid orodispersible pharmaceutical compositions in film form for oral administration of lorazepam, characterised by high stability throughout the shelf life of the product. The compositions disclosed are suitable for administration even to unconscious or dysphagic patients.

The invention belongs to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition suitable for myasthenia patients and a preparation method and application thereof. The traditional Chinese medicine is prepared from the following traditional Chinese medicine raw materials in parts by weight: 15-60 parts of astragalus membranaceus, 15-60 parts of humulus scandens, 10-30 parts of philippine flemingia root, 10-30 parts of beautiful millettia root, 10-20 parts of codonopsis pilosula, 5-15 parts of poria cocos, 5-15 parts of bighead atractylodes rhizome, 3-10 parts of liquorice, 5-15 parts of rhizoma cimicifugae, 5-15 parts of radix bupleuri, 5-15 parts of radix angelicae sinensis and 3-10 parts of pericarpium citri reticulatae. The invention solves the technical problems that the existing muscle-strengthening medicine has a limited improvement effect on symptoms such as blepharoptosis, dysphagia, weakness of limbs, soreness and weakness of waist and knees, unstable standing, difficulty in walking and the like caused by deficiency of spleen and stomach and deficiency of lower jiao kidney essence, and is not suitable for patients with fire excess from yin deficiency, liver-yang hyperactivity constitution and dampness stagnation.

Edible foods which include a selection food and provided in a form that improves swallowing in the subject are provided. The compositions include an effective combination of foods that function as TRP agonists, to provide improve swallowing in a subject in need thereof. In some forms, the compositions include: (a) hydrocolloid such as gelatin and (b) liquid juice (preferably including electrolytes) / soup component, optionally in combination with one or more additional ingredients selected from (c) a spice, (d) sweetening agent, (e) an oil, (f) a flavoring acid, (g) cocoa and (h) a pepper.

The application belongs to the technical field of food processing, and particularly relates to egg white-chlorella compound protein gel and application thereof in preparation of dysphagia adaptive food. The application provides an egg white-chlorella compound protein gel, which is obtained by heating and cross-linking of egg white protein and chlorella protein dispersed in water. The gel has high protein density (protein content is greater than or equal to 12 w / w %) and low hardness (<120 g), and its swallowing adaptability meets the international dysphagia diet standardization initiative (IDDSI) 3-5 solid food standard, so that the eating needs of patients with moderate to severe dysphagia who cannot independently control liquid intake can be met, and a new food option with high nutritional density and excellent swallowing safety is provided for the patients, so that the nutritional status of the patients can be effectively improved and the life quality of the patients can be improved.

A probiotic microsphere with in-situ proliferation, its preparation method and application. The microsphere is prepared by a two-step Pickering double emulsion method, encapsulating probiotics and panax notoginseng saponins, and then mixed with sodium alginate and cross-linked by calcium ions. The structure significantly improves the survival rate of probiotics in simulated gastric juice, intestinal juice, heat treatment and antibiotic environment, and maintains high viable cell count during long-term storage. Co-encapsulated PNS and double emulsion stabilizer natural polysaccharide-protein nanocomposite can promote the proliferation of probiotics in-situ, increase their activity. In addition, the microsphere can effectively promote the colonization and proliferation of probiotics in the intestinal tract, enhance the oral bioavailability of bioactive ingredients, and is suitable for functional food, feed, biological medicine field, especially as 3D printing special medical food for dysphagia population and prevention and treatment of intestinal inflammatory diseases.

The invention provides a dysphagia diagnosis data processing method and system. According to the method, original multi-source physiological signal data of a detected object in the swallowing process is obtained and preprocessed to obtain preprocessed signal data, candidate paragraph detection of a swallowing related event is executed based on the preprocessed signal data to obtain at least one candidate swallowing paragraph, and then the at least one candidate swallowing paragraph is detected according to the at least one candidate swallowing paragraph. And performing noise suppression and swallowing related acoustic component enhancement processing on each candidate swallowing section to obtain a noise-suppressed candidate swallowing section, and finally, extracting at least one group of acoustic characteristic parameters for representing a swallowing function state based on the noise-suppressed candidate swallowing section. Therefore, non-swallowing related background interference such as environment voice and equipment sound is effectively inhibited, the situation that conversation or equipment noise is mistakenly judged as a swallowing event is reduced, and the swallowing event detection accuracy is improved.

The present invention relates to a texturing composition comprising xanthan gum and a pectin. The texturizing composition is a gel or liquid, a powder, or a tablet. The invention further relates to various uses of such texturing composition, including medical uses, such as in the treatment of dysphagia and / or the prevention or amelioration of symptoms associated with dysphagia.

This invention discloses a cold stimulation device for the rehabilitation of dysphagia in ICU patients, belonging to the field of dysphagia rehabilitation devices. The invention provides a cold stimulation device for the rehabilitation of dysphagia in ICU patients that enhances the effect of cold stimulation therapy. It includes a horizontal plate and an inclined plate. The horizontal plate is connected to the top of the inclined plate, and the horizontal plate is connected to symmetrically arranged arc frames. A nozzle is connected between the arc frames, and three rows of nozzles are opened at the rear of the nozzle. A cylinder is connected to the side of the nozzle away from the arc frames, and a movable circular plate is slidably connected to the cylinder. By moving the connecting frame forward, the connecting frame drives a threaded rod to rotate, which in turn drives the movable circular plate to move backward, directly spraying the cold stimulation liquid through the nozzles onto the patient's throat. Firstly, the direct contact of the cold stimulation liquid with the throat allows the patient's throat to receive continuous cold stimulation; secondly, the impact force generated by the spray enhances the stimulation of the patient's throat.

The present invention provides a composition of nebivolol and amlodipine, comprising nebivolol, amlodipine and a pharmaceutical excipient. The nebivolol comprises one or more of nebivolol, a pharmaceutically acceptable salt thereof, and a solvate thereof. The amlodipine comprises one or more of amlodipine, a pharmaceutically acceptable salt thereof, and a solvate thereof. The pharmaceutical excipient is selected from one or more of a filler, a binder, a disintegrant, a lubricant, and a glidant. The composition does not contain a colorant and a film coating. The compound preparation of the present invention has good stability, and is beneficial to improving the antihypertensive efficacy, enhancing safety and tolerability, and reducing side effects. Compared to monotherapy, the present invention reduces the number of administered medications and improves the compliance of patients, is beneficial to improving the medication compliance of the elderly patients and individuals with dysphagia, maintains a stable plasma drug concentration, maintains long-term stable blood pressure in hypertensive patients, prevents the patients from discontinuing medication arbitrarily, and prevents disease recurrence and the progression of severe complications.

Disclosed in the present utility model is a speed-controllable medication feeding device for individuals with dysphagia, which aims at solving problems such as choking and aspiration caused by unstable medication feeding speeds in conventional methods. The device comprises a central core component, wherein a tail limiting plate and a tail limiting notch are provided at a rear portion of the central core component, and an auxiliary plate and a Ω-shaped tube clamping member are provided at a lower portion of the central core component so as to fix a medication feeder. During use, the extension and retraction speed of an electric telescopic rod is adjusted by means of a controller, so as to accurately control the liquid medication delivery speed. A tail limiting structure and the Ω-shaped tube clamping member ensure the stability of the medication feeder, and the design of a grip improves the operation convenience. The device can avoid the fluctuation of the manual medication feeding speed, can reduce the medication feeding risk for individuals having dysphagia, is suitable for children, elderly patients, etc., and can improve the medication feeding safety and efficiency.

Contemplated embodiments include a biomedical sensor system, comprising: a piezoresistive agent, and a flexible substrate, wherein the flexible substrate and the piezoresistive agent are coupled together to form the biomedical sensor system, and wherein the sensor system is removably located in or on the ceiling of a patient's mouth. Contemplated methods of determining a level of dysphagia in a patient include: providing a biomedical sensor system, wherein the system comprises: a piezoresistive agent, and a flexible substrate comprising a flexible hybrid circuit structure, wherein the flexible substrate and the piezoresistive agent are coupled together to form the biomedical sensor system; providing a patient having a mouth, a tongue, and a mouth ceiling, removably locating the sensor system in or on the ceiling of the patient's mouth.