237 results about "Dysphagia" patented technology

The invention relates to the technical field of monitoring, and particularly discloses an anti-esophageal reflux monitoring system for old patients with dysphagia, which is used for solving the problems of oesophageal elastic degeneration, frequent body position change, low swallowing amplitude and the like of the old patients with dysphagia. Therefore, the problem that an existing reflux monitoring system based on single-point sensing, static threshold control and periodic model updating cannot meet the dynamic reflux early warning requirements of individualization, high sensitivity, real-time performance and low power consumption is solved. Comprising a wearable esophagus comprehensive monitoring module, a body position and esophagus deformation recognition module, a personalized pressure threshold self-adaption module, an intelligent prediction and early warning module, an air bag execution module and a cloud model training and updating module. According to the invention, multi-modal sensing and dynamic threshold, self-adaptive sampling and online model fine tuning are fused, low-amplitude swallowing and early-stage reflux signals are effectively captured, the iteration period is shortened by cloud differential updating, the equipment endurance is prolonged, and the esophageal injury risk is reduced.

The present invention relates to the technical field of rehabilitation devices, and particularly relates to a rehabilitation device for dysphagia, which includes a support mechanism for supporting the whole device. A fixing ring is installed on the support mechanism, and a swinging rod is rotatably installed on the fixing ring. A swinging mechanism is installed on the fixing ring, and the swinging mechanism is used to drive the swinging rod to swing left and right around the rotating shaft; one end of the swinging rod is connected to a negative pressure tube and is internally communicated. A suction nozzle is installed at the end of the negative pressure tube far away from the swinging rod; a liquid storage tank is fixedly sleeved on the negative pressure tube; a partition plate that divides the interior of the liquid storage tank into two spaces is installed in the liquid storage tank, and a plurality of temperature adjustment mechanisms are embedded in the partition plate. The temperature adjustment mechanisms release the heat and cold generated by them into the two spaces in the liquid storage tank respectively. This device directly uses pressurized hot and cold liquids to change the shape of the suction nozzle at the front end, so that the device can not only fix the tongue tip by negative pressure for tongue extension training, but also perform hot and cold stimulation on the target area of the patient's oral cavity.

The invention belongs to the technical field of assessment of dysphagia of stroke patients, and provides a stroke patient dysphagia risk prediction and personalized intervention recommendation system based on R language construction, which comprises a data processing module, a prediction model module, an intervention recommendation module and an output module, the data processing module receives and processes an input predictive factor value, the predictive model module constructed based on a large amount of case data is used for calculating a dysphagia risk score, then the intervention recommendation module intelligently recommends personalized intervention measures, and the personalized intervention measures are displayed to a user in a visual form through the output module; according to the system, accurate prediction and personalized intervention recommendation of the dysphagia risk of the stroke patient are realized, the prediction accuracy and reliability are improved, meanwhile, the pertinence and effectiveness of intervention measures are enhanced, and the life quality and rehabilitation effect of the patient are improved.

The invention discloses pea starch-quinoa protein soft gel and a preparation method thereof. The pea starch-quinoa protein soft gel is prepared from pea starch and quinoa protein. The mass ratio of the pea starch to the quinoa protein is 10: (2-3); the IDDSI rating of the pea starch-quinoa protein soft gel is grade 4, the water binding capacity is 76.71 + / -0.12%, the hardness is 1.514 + / -0.017 N, the breaking strength is 0.976 + / -0.004 N, and the apparent viscosity is 473.6 + / -9.1 Pa.s. By optimizing the proportion and processing conditions of the pea starch and the quinoa protein, the soft gel which is easy to swallow and has high nutritional value and good taste is prepared, so that the special diet requirements of old people with dysphagia are met.

The invention belongs to the technical field of brain-computer interfaces, and particularly relates to a post-stroke dysphagia rehabilitation recognition system, feedback stimulation equipment and a storage medium. The system comprises a signal acquisition module, an electroencephalogram signal preprocessing module, a neural network feature extraction module, a statistical feature extraction module and a swallowing intention recognition module, and can recognize whether a patient has a swallowing intention or not through a Mama deep learning model based on space-time statistical features. The invention also constructs brain-computer interface equipment for rehabilitation of dysphagia after stroke in combination with electroencephalogram signal acquisition equipment and electrical stimulation equipment. The technical scheme of the invention has the advantages of being accurate in recognition, good in rehabilitation treatment effect and capable of forming center-periphery closed loop feedback, and has a very good application prospect.

Described herein are methods of managing eosinophilic esophagitis (EoE) in a patient, wherein the patient records the number of episodes of dysphagia on a patient report outcome (PRO) questionnaire prior to and during the course of treatment. While on treatment, the number of episodes of dysphagia are reduced, as reported on the PRO questionnaire. In some embodiments, the esophageal eosinophils are counted before or after treatment, or both. In some embodiments, esophageal eosinophils counts are not correlated with a reduction in the episodes of dysphagia.

The invention belongs to the field of food processing, and provides a preparation method of penaeus vannamei powder gel suitable for people with dysphagia, which comprises the following steps: taking penaeus vannamei meat, blending until no obvious particles exist, freezing, carrying out vacuum drying, powdering, sieving, mixing with water, fully hydrating to obtain a penaeus vannamei powder solution, adjusting the pH value of the penaeus vannamei powder solution to 9-11, stirring, adjusting the pH value to 6-8, and preparing the penaeus vannamei powder gel. And continuously stirring, adding carrageenan, heating and cooling to obtain the penaeus vannamei meal gel. The method disclosed by the invention is simple and easy to implement, and the pH migration treatment and the carrageenan treatment are utilized to generate a synergistic effect, so that the prepared penaeus vannamei powder gel meets the fifth-level standard of an IDDSI framework, and can meet the diet requirements of special crowds such as dysphagia patients on multiple aspects such as nutrition and texture.

Disclosed are an ibuprofen pharmaceutical composition, and a preparation method therefor and the use thereof. The ibuprofen pharmaceutical composition comprises the following components: sustained-release pellets and immediate-release pellets, wherein the sustained-release pellets comprise ibuprofen, a filler and an adhesive; and the immediate-release pellets comprise ibuprofen, a filler, a suspending agent, a disintegrant, a flavoring agent and a pH regulator. The ibuprofen pharmaceutical composition takes effect quickly and can maintain a therapeutic effect for a long time. The administration compliance of children, elderly people and people with dysphagia can be effectively improved, and the administration frequency is reduced. A dry deposition particle has a wide loading range, and the presence of the dry deposition particle during drug storage and transportation is beneficial for maintaining the stability during drug storage and transportation. In addition, the ibuprofen pharmaceutical composition has the advantages of a simple preparation process, stable properties and convenient administration, and is suitable for industrial production.

The invention discloses a Doppler ultrasonic diagnosis system for dysphagia detection, and belongs to the technical field of Doppler ultrasonic diagnosis. The method comprises the following steps: respectively measuring the geniolingual muscle movement, swallowing time, tongue movement and the distance between the tongue bone and the thyroid cartilage of a stroke patient in a B-type ultrasonic mode and an M-type ultrasonic mode, recording test data after multiple swallowing tests, calculating to obtain an average value of the geniolingual muscle movement, the swallowing time, the tongue movement and the distance between the tongue bone and the thyroid cartilage, and calculating the average value of the geniolingual muscle movement, the swallowing time, the tongue movement and the distance between the tongue bone and the thyroid cartilage. Then the measurement results of the swallowing time and the distance between the tongue bone and the thyroid cartilage are used as evaluation and diagnosis bases for diagnosis, so that objective and accurate diagnosis bases are provided for the treatment and rehabilitation process of the swallowing dysfunction of a stroke patient, and nursing personnel can evaluate and diagnose the swallowing dysfunction after the stroke by using a simple B-ultrasonic instrument at the bedside; and the diagnosis accuracy of medical personnel is improved.

The invention discloses a subcutaneous administration intelligent health management system based on dynamic data, and relates to a medical instrument. According to the system, the data monitoring system, the drug delivery strategy calculation system and the subcutaneous drug delivery system are adopted for monitoring and processing health data and quickly responding to drug intervention, so that the problem that only health data can be monitored and health suggestions can be provided at the present stage, and abnormal health conditions cannot be handled in time is solved; according to the full-automatic management method of'detection, diagnosis and administration ', the compliance of a patient is improved; personalized and intelligent real-time administration calculation is achieved, the effect is guaranteed, meanwhile, the dosage of the medicine is reduced to the maximum extent, and side effects are reduced; the non-invasive transdermal drug delivery performed by using the microneedle system can reduce the problem of low bioavailability of the drug due to the effects of first pass metabolism and the like, and is more friendly to patients with dysphagia.

The use of a device to measure patient sensory response through the application of an incrementally increased electrical current to the oropharynx.

The invention relates to the technical field of 3D printing food, in particular to a preparation method of lotus root whole powder composite whey protein 3D printing food suitable for people with dysphagia, and the preparation method comprises the following steps: preparing lotus root whole powder from fresh lotus roots; lotus root whole powder and whey protein are mixed, distilled water is added to prepare suspension liquid, the suspension liquid is homogenized, then the suspension liquid is put into a water bath kettle to be stirred at a high temperature, the mixture is transferred into a 3D printer charging barrel to be subjected to water bath treatment, and composite printing ink is obtained; a food 3D printer is used for printing, and the lotus root whole powder composite whey protein 3D printing food is prepared. The lotus root whole powder and the whey protein are used as basic raw materials, the material ratio, the gelatinization time, the gelatinization temperature and the rotating speed are optimized, 3D printing of the lotus root whole powder composite whey protein is achieved, the precision of printed products is guaranteed, materials of the food 3D printing industry are enriched, printed food can be better suitable for diet of people with dysphagia, and the food quality is improved. Wide application prospects and market values are realized.

The invention relates to the technical field of food processing, in particular to fish-derived protein gel special for 3D printing dysphagia and having a customized digestion characteristic and a lycopene release function as well as a preparation method and application of the fish-derived protein gel. The lycopene-loaded IN / KGM gel system is constructed by combining a food additive manufacturing technology and a dynamic old people digestion model, and the rheological property and swallowing safety of the gel are optimized by regulating and controlling the ratio of IN to KGM; the customized digestion characteristics of the gel and the adaptability of the gel to the digestion function of the old people are researched by utilizing an in-vitro dynamic digestion model of the old people; the loading and releasing behaviors of lycopene in a gel system are explored, the bioaccessibility of lycopene in the gastrointestinal digestion process of old people is evaluated, the interaction mechanism of IN and KGM in the gel forming and digestion process is disclosed, and a theoretical basis and technical support are provided for developing personalized nutritious food suitable for the old people with dysphagia.

The invention discloses a risk prediction method for patients with Parkinson's dysphagia, and relates to the technical field of medical health. The method comprises the steps that S1, a multi-modal data fusion framework is built, the multi-modal data fusion framework aims at effectively fusing biomarkers, dynamic swallowing kinematics characteristics and clinical data, the core of the multi-modal data fusion framework comprises characteristic alignment, inter-modal interaction modeling and fusion decision, and a first risk prediction probability is output; through a multi-modal data fusion algorithm, a dynamic swallowing function quantification technology and a lightweight edge deployment scheme, high-precision prediction, early warning and personalized intervention of the Parkinson's dysphagia risk are realized, the method has remarkable clinical value, technical barriers and market competitiveness, and the core demand of medical productization landing is met.

The invention discloses a dysphagia rehabilitation training device which is characterized by comprising a base, a control panel, a water tank, a water pump and a training mechanism. The training mechanism comprises a plurality of electric push rods arranged in a lower cavity of an adjusting frame at equal intervals, a plurality of sleeves are arranged in an upper cavity of the adjusting frame at equal intervals, pistons are arranged at the output ends of the electric push rods and slidably mounted in the sleeves, and a supporting rod of an L-shaped structure is fixedly mounted at the top of the adjusting frame. A peristaltic pipe is arranged at the front end of the supporting rod, a stimulation ball is arranged at the front end of the peristaltic pipe, a plurality of air pipes are connected to the interior of the peristaltic pipe, the air pipes are slidably installed in the supporting rod, the tail ends of the air pipes are connected to the top of the sleeve, and a water outlet pipe and a water inlet pipe are arranged at the tail end of the stimulation ball; the water inlet pipe and the water outlet pipe are slidably mounted in the supporting rod; the device can guide the root of the tongue, stimulate the pharynx and train swallowing muscles at the same time.

The invention discloses a machine vision-based dysphagia risk identification method and system for an elderly patient, and belongs to the technical field of dysphagia, and the method comprises the following steps: S1, collecting real-time image data of the swallowing of the elderly patient; s2, processing the swallowing real-time image data of the elderly patient, and determining swallowing feature data of the elderly patient; s3, determining an optimal elderly patient dysphagia risk identification model; s4, analyzing and identifying the swallowing characteristic data of the elderly patient, and judging whether the elderly patient has the risk of dysphagia or not; s5, early warning feedback intervention measures are taken in time, and life safety and life quality of the elderly patients are guaranteed. The problem that effective risk identification and timely protection intervention cannot be carried out on dysphagia of old patients in the prior art is solved. According to the invention, effective risk identification and timely protection intervention can be carried out on dysphagia of the elderly patient, and life safety and life quality of the elderly patient can be effectively guaranteed.

The invention relates to the technical field of medical instruments, in particular to an ice stimulation training device for dysphagia rehabilitation, which comprises a box body with an upward opening, a cover plate arranged at the opening of the top of the box body, two partition plates arranged in an internal cavity at an interval up and down, and an auxiliary opening mechanism arranged in a training opening in the front side of the box body and used for opening the box body. An ice stimulation training head is arranged in the ice stimulation training device, the tail of the ice stimulation training head is connected with a control mechanism, and a pneumatic assembly is arranged on the left side of the top of the partition plate on the upper side and connected with the auxiliary opening mechanism through an air pressure rod assembly. The problems that in the prior art, an ice stimulation training device for rehabilitation of the stroke dysphagia generally can only achieve single ice stimulation treatment and lacks auxiliary taste stimulation and vibration stimulation for comprehensive treatment, so that the whole treatment process is long in time, more complex and free of cooperation, and the treatment cost is low are solved. Meanwhile, the compliance of the patient and the recognition degree of treatment are also reduced, and the patient cannot recover as soon as possible.

The invention discloses a dysphagia pill fingerprint spectrum establishment method and an established fingerprint spectrum, belongs to the technical field of analysis and detection of traditional Chinese medicine preparations, and provides a dysphagia pill fingerprint spectrum establishment method which comprises the following steps: mixing a dysphagia pill test sample with petroleum ether, performing Soxhlet extraction, mixing medicine residues with a methanol aqueous solution, performing heating reflux, performing column chromatography, and performing freeze drying to obtain a dysphagia pill fingerprint spectrum. Taking filtrate to obtain a test solution; mixing ellagic acid, liquiritin, ammonium glycyrrhizinate and sesamin reference substances with methanol to obtain a mixed reference substance solution; sucking the test solution and the reference solution, injecting into a liquid chromatograph, and collecting a chromatogram; introducing the chromatogram of the test sample into a traditional Chinese medicine chromatographic fingerprint spectrum similarity evaluation system, selecting common chromatographic peaks as common peaks, generating a dysphagia pill contrast fingerprint spectrum, and calculating the relative retention time and the relative peak area of each common peak to obtain the HPLC fingerprint spectrum of the dysphagia pill. The quality of the dysphagia pill can be comprehensively evaluated by using the map, and the quality stability, consistency and controllability of the dysphagia pill are ensured.

Devices and methods for assisting a patient with recovery from dysphagia are disclosed herein. In some embodiments, the device comprises a catheter with sections whose curvatures correspond to curves between external nares of the patient and a nasal cavity and between the nasal cavity and a nasopharynx. The device may further include an electrode at a distal portion of the catheter and configured to deliver stimulation energy to nearby tissue.

The invention provides a dysphagia preventing device special for nursing of psychiatric patients, and relates to the technical field of nursing equipment. The dysphagia prevention device special for nursing of the psychiatric patient comprises a main fixing table, a head and neck fixing mechanism, lip fixing mechanisms and a tongue fixing mechanism, the head and neck fixing mechanism is arranged on one side of the top of the main fixing table, and four sets of lip fixing mechanisms are arranged on the other side, opposite to the head and neck fixing mechanism, of the top of the main fixing table; a tongue fixing mechanism is fixedly connected to the top of the main fixing table and located among the four lip fixing mechanisms. The tongue is fixed through a tongue depressor of the tongue fixing mechanism, the suffocation condition caused by the fact that the tongue slides to the throat can be effectively prevented, the airway smoothness is ensured, automatic devices such as a motor drive device are used in the technical scheme, operation is more convenient and efficient, medical staff can quickly and accurately complete fixing and treatment operation, and the working efficiency is improved. And the working efficiency is improved.

The invention provides a loxoprofen sodium double-release capsule micro-tablet and a preparation method of the loxoprofen sodium double-release capsule micro-tablet. Through the synergistic effect of the quick-release micro-tablet and the sustained-release micro-tablet, the quick-release micro-tablet can realize quick release and absorption, and the sustained-release micro-tablet can maintain relatively stable blood concentration for a long time. The administration frequency is reduced, the coordination of the postprandial administration requirement and the dietary habit is ensured, and the occurrence of gastrointestinal tract adverse reactions is reduced. The preparation provided by the invention conforms to the dosage form design of the hour pharmacology, can quickly take effect through administration twice every day, can maintain the blood concentration in the high-incidence time period of night diseases, avoids the disadvantage of taking medicine after meal when the night diseases attack, guarantees the sleep quality, and improves the overall treatment effect. The micro tablet is small in size and easy to swallow, and the medication compliance of patients with dysphagia is obviously improved. Through dosage form design and improvement, unmet clinical requirements are expected to be met by virtue of obvious advantages of the traditional Chinese medicine composition.

The invention belongs to the technical field of medical treatment, and provides a dysphagia rehabilitation training method based on VR (virtual reality) equipment aiming at the problem that the existing dysphagia treatment cannot accurately recognize the dysphagia action of a patient and cannot provide a personalized rehabilitation scheme. The method comprises the following steps: acquiring a first electromyographic signal swallowing by a healthy person and a second electromyographic signal swallowing by a patient, slicing the signals by using an LSTM model, and comparing the difference between the two signals through a specially designed sliding window to determine the obstacle action of the patient; simulating treatment effects of different swallowing actions based on a neural network model, and selecting the swallowing action with the highest learning rate; and finally, making the action into a VR training model, and guiding the patient to train by virtue of VR equipment. According to the invention, by accurately diagnosing the dysphagia action, formulating a personalized treatment scheme and utilizing the VR technology, the training effect and interestingness of patient training are enhanced, and the quality of dysphagia rehabilitation training is effectively improved.

The invention provides a dysphagia screening system based on computer vision, and relates to the technical field of image recognition, and the system comprises an image collection module which collects image data of a swallowing event to obtain a time sequence image sequence; the motion field establishing module is used for extracting a motion point track sequence according to the time sequence image sequence and establishing a global motion transformation field; the motion separation module is used for carrying out registration correction on the global motion transformation field and carrying out motion separation on the stabilized image sequence to obtain local deformation components; the region segmentation module is used for carrying out key region segmentation on the local deformation components to obtain swallowing function parameters; and the risk identification module is used for identifying the obstacle risk of the swallowing function parameters and generating a swallowing obstacle screening report. According to the method and the device, the technical problem of relatively poor screening accuracy of the dysphagia based on the computer vision in the prior art can be solved, and the technical effect of improving the screening accuracy of the dysphagia based on the computer vision is achieved.

The invention relates to the technical field of 3D printing of easy-to-swallow food, in particular to a protein-based nanoparticle gel double-nozzle 3D printing method and equipment, aiming at the nutritional requirements of old people with dysphagia, procyanidine is loaded on protein-based nanoparticles, corn starch, gelatin and the like are combined to construct a composite gel system as a printing wall material, and the printing wall material is used as a printing wall material. Protein, citrus juice and peony seed oil emulsion are used as core materials, and a double-nozzle 3D printing technology is utilized to realize accurate texture regulation and control and personalized nutrition design; the method comprises the steps of protein solution preparation, composite nanoparticle synthesis, procyanidine loading, wall material and core material preparation, double-nozzle printing and the like, the technology breaks through the bottleneck that traditional swallowing food is insufficient in protein strengthening and lacks active ingredients, and the antioxidant functional components and the 3D printing technology are integrated; innovative food with swallowing safety and nutrition targeting is provided for the elderly, and application of protein-based materials in intelligent food manufacturing is promoted.

The invention relates to the technical field of physical disorder assessment, and discloses a method and a system for monitoring and assessing the swallowing function of a stroke patient, and the method comprises the steps: collecting the electromyographic signals of the sEMG of the sEMG of the stroke patient through arranging a multi-channel sEMG electrode; and based on the acquired multi-channel electromyographic signals, performing analysis processing through Fourier transform and a machine learning algorithm combining independent component analysis and wavelet transform to obtain an analysis result of deep muscle electrical activity and an independent activity result of different muscle groups, and based on the result, evaluating the swallowing function of the stroke patient. Therefore, the functional conditions of specific muscles and deep muscles are mastered, the accuracy of screening and evaluating dysphagia of a stroke patient is improved, and effective support is provided for subsequent clinical diagnosis.

The utility model discloses an esophageal hiatus hernia patch structure, which belongs to the technical field of hernia patch structures, a hernia patch main body consists of a hollow part, a hernia patch upper part, a hernia patch left part and a hernia patch lower part, and a fixed lower hernia patch and a movable upper hernia patch are sleeved on the hernia patch main body. The upper hernia patch body is in sliding connection along the sliding attaching cavity in the hernia patch body through the limiting sliding block, the lower hernia patch body and the upper hernia patch body are of an elastic structure and an extrudable structure, the hernia patch body is placed at the position of an esophageal fissure for filling and fixing the length and width of all boundaries, the probability that cutting is needed in an operation is small, the operation time is saved, and the operation efficiency is improved. The size of the esophageal crack is standardized as the target, the unsolid closed opening of the patch has certain extensibility, the postoperative dysphagia complication is further relieved, the patch of the model further reinforces the front wall of the esophageal crack, the recurrence of hernia is further reduced, and the high-adaptation and adjustable functions are achieved.

The invention discloses a method for directionally regulating and controlling fish-source protein soft gel by utilizing electrostatic deposition microcapsules, and belongs to the technical field of aquatic product processing. The preparation method comprises the following steps: compounding pea protein isolate-beta-glucan complex coacervate and vegetable fat to obtain complex coacervation microcapsules, and coating the complex coacervation microcapsules with a carboxymethyl chitosan electrostatic deposition layer under a pH induction condition by utilizing electrostatic attraction; an electrostatic deposition microcapsule is added into a minced fillet raw material, and a soft minced fillet gel system based on fish source protein is constructed by utilizing the unique thickening characteristic and gel forming ability of the electrostatic deposition microcapsule. Directional regulation and control on the texture of the minced fillet are realized by utilizing the microcapsules, and the texture of the minced fillet gel is improved, so that the product is finer and softer, and is more suitable for the mouth feel requirements of special crowds such as old people and patients with dysphagia; the nutritional and healthy value of the minced fillet soft gel can be improved, and the nutritional value of the product is enhanced by adding specific nutritional ingredients into the microcapsules, so that the minced fillet soft gel becomes an ideal nutritional supplement source for the type of people.

The invention discloses PSE-like chicken breast composite gel soft food suitable for people with dysphagia and a preparation method of the PSE-like chicken breast composite gel soft food, and belongs to the field of food processing. The raw materials of the composite gel soft food comprise PSE-like chicken breast, konjac glucomannan and a sodium chloride solution, and the preparation method comprises the following steps: adding a mixed solution of konjac glucomannan and sodium chloride into PSE-like chicken breast, stirring, carrying out heating treatment after uniform stirring, and then cooling to obtain the PSE-like chicken breast composite gel soft food. The prepared food is stable in total protein content, can effectively make up for insufficient intake of meat protein caused by limited feeding of people with dysphagia, and prevents malnutrition; the product texture meets the swallowing requirement, reaches the IDDSI level 5 or level 6 standard, can effectively reduce the risk of food residue and aspiration in the swallowing process, and has nutrition balance and food safety.

The invention provides a stroke dysphagia rehabilitation training interaction method and system, and relates to the technical field of wisdom medical treatment, and the method constructs a closed-loop and multi-dimensional rehabilitation interaction system through integrating four modules of swallowing function evaluation, course execution, psychological state monitoring and AR gamification training. A patient can complete structured evaluation of swallowing ability and a family support environment on a main interface in a one-stop mode, an adjustable personalized rehabilitation path is generated accordingly, and feedback is dynamically collected and executed in the training process to optimize course content; meanwhile, the emotion evaluation mechanism can timely identify negative psychological states and automatically trigger regulation intervention; by combining the augmented reality technology, food or tableware is recognized in real time in a real feeding scene, risk prompt and safety guidance are overlaid, the training interestingness and compliance are improved through interactive games, finally individuation, visualization, emotional and immersive fusion of the rehabilitation process is achieved, and the rehabilitation effect and life quality of stroke dysphagia patients are improved.

An oral liquid suspension comprising atomoxetine or a pharmaceutically acceptable salt thereof is disclosed, formulated at a concentration of about 20 mg / mL for the treatment of attention-deficit / hyperactivity disorder (ADHD). The suspension includes a dual preservative system (methylparaben and sodium benzoate), sweeteners, pH buffers, suspending agents, co-solvents, flavorants, and colorants. The composition demonstrates bioequivalence to Strattera® capsules, robust antimicrobial efficacy meeting USP <51> criteria, and physicochemical stability over 24 months in validated high-density polyethylene containers with child-resistant closures. The 20 mg / mL concentration enables precise dose titration for pediatric and dysphagic patients. Palatability is optimized through validated flavor masking studies, supporting high patient adherence. The invention further provides scalable manufacturing methods, quality control specifications, and methods of use for treating ADHD, offering a stable, safe, and patient-friendly alternative to solid oral dosage forms.