28 results about "Esophageal reflux" patented technology

The invention relates to the technical field of monitoring, and particularly discloses an anti-esophageal reflux monitoring system for old patients with dysphagia, which is used for solving the problems of oesophageal elastic degeneration, frequent body position change, low swallowing amplitude and the like of the old patients with dysphagia. Therefore, the problem that an existing reflux monitoring system based on single-point sensing, static threshold control and periodic model updating cannot meet the dynamic reflux early warning requirements of individualization, high sensitivity, real-time performance and low power consumption is solved. Comprising a wearable esophagus comprehensive monitoring module, a body position and esophagus deformation recognition module, a personalized pressure threshold self-adaption module, an intelligent prediction and early warning module, an air bag execution module and a cloud model training and updating module. According to the invention, multi-modal sensing and dynamic threshold, self-adaptive sampling and online model fine tuning are fused, low-amplitude swallowing and early-stage reflux signals are effectively captured, the iteration period is shortened by cloud differential updating, the equipment endurance is prolonged, and the esophageal injury risk is reduced.

The invention provides an application of a Lactobacillus paracasei IOB413 metagen in gastroesophageal reflux, and belongs to the technical field of microbial fermentation. The lactobacillus paracasei IOB413 metagen can relieve weight loss of gastroesophageal reflux rats, inhibit esophageal reflux, relieve esophageal tissue pathological injury, relieve inflammatory injury by reducing the levels of inflammatory factors IL-17 and IL-8, and enhance gastrointestinal motility and reduce the risk of reflux by improving the motilin level.

The invention provides a recessive gastroesophageal reflux event data analysis system and method based on dynamic changes of abdominal pressure. The system and method are suitable for noninvasive detection of atypical reflux clinically. The system comprises an abdominal pressure dynamic detection unit, a throat vibration detection unit, a multi-mode signal processing module, a reflux event judgment module and a data output module. According to the system, by analyzing time sequence linkage between abdominal pressure mutation and throat vibration, a stomach content countercurrent event is recognized, silent type countercurrent characteristic sound is captured with the assistance of a bone conduction sound wave channel, and multi-path redundancy recognition is achieved. The method is suitable for postoperative patients, children, old people and other people who cannot complain, has the technical advantages of continuous wearing, behavior correlation analysis and clinical verifiability, and significantly improves the recognition rate and diagnosis accuracy of recessive gastroesophageal reflux events.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating gastroesophageal reflux cough and a preparation method thereof. The traditional Chinese medicine composition disclosed by the invention is constructed by carefully selecting a medicine formula under the guidance of a traditional Chinese medicine theory and clinical experience and through a compatibility theory of monarch, minister, assistant and guide of traditional Chinese medicines. In the traditional Chinese medicine composition, the inula flower has the effects of promoting blood circulation, removing stasis and turbidity, clearing the airway and removing phlegm and fluid retention, and the mangnolia officinalis has the effects of promoting qi circulation, removing food retention, calming adverse-rising energy and relieving asthma, and both serve as monarch drugs; the dried orange peel has the effects of regulating qi and removing stagnation, the poria cocos has the effects of tonifying spleen, eliminating dampness and phlegm and breaking up the source of phlegm, and the bulbus fritillariae cirrhosae has the effects of clearing heat and moistening lung and resolving phlegm and relieving asthma; the rhizoma atractylodis macrocephalae has the effects of invigorating the spleen, replenishing qi, eliminating dampness and inducing diuresis, and the endothelium corneum gigeriae galli has the effects of promoting digestion and invigorating the stomach and is an assistant and guide drug. The whole prescription is ordered in monarch and minister, focuses on pathogenesis, is rigorous in prescription, has the effects of relieving cough and asthma, clearing heat and moistening lung, and strengthening spleen and stomach, and treats both symptoms and root causes of cough.

The gastroesophageal collar being submitted for patent intends to primarily prevent the ascension of the fundus above the diaphragmatic plane and also secondarily to improve the function of the Lower esophageal sphincter, thirdly to reduce occurrences of esophageal reflux and thereby hopefully reducing instances of esophageal cancer. It is estimated as high as %20 of the general population has a hiatal hernia experiencing symptoms of acid reflux and making them at higher risk for esophageal cancer. Currently the standard surgical repair of hiatus is fundoplication. The limitations of fundoplication are its high recurrence rate. It often requires a later second procedure to repair / tighten the fundoplication. By using supple bio-inert materials we intend to create a collar that can be left in place, mechanically preventing the ascension of the fundus and improving LES function. We hope to be the first Collar to prevent hiatal hernia and also improve LES function.

The present invention relates to an anti-respiratory obstruction device during anesthesia nursing, belonging to the field of medical device technology, comprising an oropharyngeal folding pressure plate, an airway intubation channel, an esophageal intubation hole, an esophageal reflux prevention tube, an oral secretion suction hole, a monitoring camera and a central controller. The present invention provides an anti-respiratory obstruction device that is simultaneously equipped with an esophageal reflux prevention blocking structure, an oral secretion infiltration prevention structure and an airway clearing monitoring structure. The esophageal reflux prevention tube is combined with an inner monitor to facilitate preventive monitoring and timely suction of reflux when obstruction occurs. The oropharyngeal folding pressure plate is used to moderately press the oropharynx in combination with the oral secretion suction hole thereon, which is conducive to clearing secretions in real time to prevent secretions that may cause obstruction from entering the oropharynx and airway. The air vent is provided to ensure assisted breathing when respiratory obstruction occurs, ultimately achieving comprehensive prevention of respiratory obstruction and effective and rapid treatment when respiratory obstruction occurs.

The present application relates to the field of food technology, and specifically discloses a composition for reducing gastroesophageal reflux in individuals, a preparation method and application thereof. The composition for reducing gastroesophageal reflux in individuals comprises beta-defensin 1, lysozyme and lactoperoxidase. The present application constructs a multi-target synergistic intervention mechanism combining physical protection, secretion regulation and tissue repair through the compounding of four core components, which can comprehensively block the occurrence and development of gastroesophageal reflux. Lactadherin constructs a physical barrier to reduce the risk of reflux dynamics from the source; MLCT precisely regulates gastric acid secretion to reduce chemical stimulation; HMO complex IgG strengthens the mucosal immune barrier and promotes damage repair. The above composition is applied to products for reducing gastroesophageal reflux in individuals, and multi-target synergistic effect is achieved, realizing a full-chain closed-loop intervention from prevention, relief to repair, and significantly improving the clinical improvement effect.

The present application relates to the field of special medicine, and more specifically, it relates to a thickening component for special medical purposes for dysphagia and gastroesophageal reflux and a preparation method. A thickening component for special medical purposes for dysphagia and gastroesophageal reflux, comprising modified starch and xanthan gum; wherein the mass ratio of modified starch to xanthan gum is (7~9.5):(3~0.5). The preparation method is as follows: fully hydrating the modified starch to obtain a modified starch solution; spray drying part of the modified starch solution to prepare a powder; spraying the xanthan gum solution from the bottom of a fluidized bed to granulate the modified starch powder; spraying the remaining modified starch solution from the top of the fluidized bed to coat the above granulation, and sieving after hot air drying to obtain the finished product. The present application has the advantage of simultaneously improving the symptoms of dysphagia and gastroesophageal reflux.

Disclosed are tetrahydroisoquinoline compounds useful for treating an opioid receptor-associated condition including pain, immune disease, esophageal reflux, diarrhea, anxiety, or heroin addiction. Also provided are pharmaceutical compositions and treatment methods.

The invention belongs to the technical field of gastroscopy, and particularly relates to an auxiliary device for gastroesophageal reflux examination, which comprises an expansion and shrinkage sleeve assembly and a gastroscope assembly, the diameter of the expansion and shrinkage sleeve assembly can be changed, when the diameter of the expansion and shrinkage sleeve assembly is at the minimum value, the diameter of the expansion and shrinkage sleeve assembly is smaller than that of the gastroscope assembly, and when the diameter of the expansion and shrinkage sleeve assembly is at the minimum value, the diameter of the gastroscope assembly is smaller than that of the gastroscope assembly. When the diameter of the expansion and shrinkage sleeve assembly is at the maximum value, the gastroscope assembly can be inserted into the expansion and shrinkage sleeve assembly in a sliding mode. The double-layer cannula insertion structure is adopted, firstly, the expansion and shrinkage cannula assembly which is small in diameter and is in a shrinkage state is inserted into the esophagus, and therefore the discomfort of a patient is reduced; then, the expansion-shrinkage sleeve assembly is unfolded and converted into a hollow tube structure with a larger diameter from a folded and shrunk state, and then the gastroscope assembly is inserted into the expansion-shrinkage sleeve assembly, so that insertion of the gastroscope is completed.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating gastroesophageal reflux cough and a preparation method thereof. The traditional Chinese medicine composition disclosed by the invention is constructed by carefully selecting a medicine formula under the guidance of a traditional Chinese medicine theory and clinical experience and through a compatibility theory of monarch, minister, assistant and guide of traditional Chinese medicines. In the traditional Chinese medicine composition, the inula flower has the effects of promoting blood circulation, removing stasis and turbidity, clearing the airway and removing phlegm and fluid retention, and the mangnolia officinalis has the effects of promoting qi circulation, removing food retention, calming adverse-rising energy and relieving asthma, and both serve as monarch drugs; the dried orange peel has the effects of regulating qi and removing stagnation, the poria cocos has the effects of tonifying spleen, eliminating dampness and phlegm and breaking up the source of phlegm, and the bulbus fritillariae cirrhosae has the effects of clearing heat and moistening lung and resolving phlegm and relieving asthma; the rhizoma atractylodis macrocephalae has the effects of invigorating the spleen, replenishing qi, eliminating dampness and inducing diuresis, and the endothelium corneum gigeriae galli has the effects of promoting digestion and invigorating the stomach and is an assistant and guide drug. The whole prescription is ordered in monarch and minister, focuses on pathogenesis, is rigorous in prescription, has the effects of relieving cough and asthma, clearing heat and moistening lung, and strengthening spleen and stomach, and treats both symptoms and root causes of cough.

The invention discloses a gastroesophageal reflux AI auxiliary typing method based on esophageal function and morphological characteristics, and belongs to the technical field of gastroesophageal reflux, a first index parameter is acquired, esophageal functional characteristics are evaluated by using a pre-training model according to the first index parameter, and a functional score is calculated; wherein the first index parameter comprises a high-resolution esophageal power index parameter and an esophageal pH-impedance combined index parameter; obtaining esophageal endoscopic image index parameters, and according to the esophageal endoscopic image index parameters, evaluating the severity of the foraminal hernia defect and cardia relaxation by using the deep learning convolutional neural network prediction model, and calculating a morphological score; comprehensively evaluating the severity of the gastroesophageal reflux according to the functional score and the morphological score, and completing the precise typing of the gastroesophageal reflux. The severity of esophageal dysfunction and morphological defect is effectively evaluated based on a comprehensive index evaluation system, and precise typing of gastroesophageal reflux disease is completed.

The invention relates to the technical field of medical instruments, in particular to an external compression device for preventing esophageal regurgitation, which comprises a belt ring, a groove is formed in the outer side of one end of the belt ring, a plurality of adjusting teeth are fixedly mounted in the groove at equal intervals, and the other end of the belt ring is fixedly sleeved with a limiting seat. A sponge lining, a pressure air bag and a plurality of air pillows are fixedly installed on the inner side of the belt ring, a detection hose is fixedly inserted into the side face of the pressure air bag, and a pressure gauge is fixedly installed at the end, away from the pressure air bag, of the detection hose; the device has the advantages that the belt ring is wound around the neck of a patient, the belt ring is driven to be slowly tightened through the adjusting mechanism, the tightness of the belt ring can be accurately adjusted through the arranged adjusting mechanism, the belt ring can adapt to different patients, and the comfort level of the patients is improved; and through the arranged one-way locking mechanism, the belt ring is prevented from being automatically loosened, and the pressure air bag can stably and continuously press the annular cartilage of the patient.

Disclosed are tetrahydroisoquinoline compounds useful for treating an opioid receptor- associated condition including pain, immune disease, esophageal reflux, diarrhea, anxiety, or heroin addiction. Also provided are pharmaceutical compositions and treatment methods.

The invention discloses a medicinal moxa composition for preventing and treating chronic gastroenteritis combined with esophageal reflux, which comprises rhizoma atractylodis, wrinkled gianthyssop herb, fortune eupatorium herb and moxa, and can improve the symptoms of chronic gastroenteritis and esophageal reflux through the effects of strengthening spleen and stomach, eliminating dampness and dissolving turbidity, regulating qi and relieving pain and the like. Agastache rugosus is used for resolving dampness and regulating the middle warmer, fortune eupatorium herb is used for enlivening the spleen and promoting appetite, and the four medicines are compatible to form a balanced system for strengthening the spleen and stomach and eliminating dampness and turbidity. A plurality of volatile active ingredients of the medicinal moxa composition act on a plurality of key targets related to chronic gastroenteritis and esophageal reflux co-disease through moxibustion. Volatile components generated by combustion of the medicinal moxa composition directly act on esophageal mucosa and spleen and stomach areas, a'local-whole body 'synergistic effect mode is formed in combination with a warm effect and meridian stimulation, and a new thought and theoretical basis are provided for prevention and treatment of chronic gastroenteritis combined with esophageal reflux.

The present application belongs to the technical field of gastroscopy, and particularly relates to an auxiliary device for gastroesophageal reflux examination, which comprises an expandable sleeve assembly and a gastroscope assembly. The diameter of the expandable sleeve assembly can be changed. When the diameter of the expandable sleeve assembly is at a minimum value, the diameter of the expandable sleeve assembly is smaller than that of the gastroscope assembly. When the diameter of the expandable sleeve assembly is at a maximum value, the gastroscope assembly can be slidably inserted into the inside of the expandable sleeve assembly. The present application adopts a double-layer sleeve insertion structure. First, the expandable sleeve assembly in a contracted state with a smaller diameter is inserted into the esophagus to reduce the discomfort of the patient. Then, the expandable sleeve assembly is unfolded from the folded and contracted state to a hollow tube structure with a larger diameter. Then, the gastroscope assembly is inserted into the inside of the expandable sleeve assembly to complete the insertion of the gastroscope.

The utility model relates to an animal experiment device. The utility model discloses a gastroesophageal reflux chest pain modeling and treatment combined animal experiment device. The animal experiment device comprises a centralized sleeve, a fixed gastric sac assembly, an esophageal physical stimulation balloon assembly and a medicine stimulation assembly, the fixed gastric sac assembly comprises a first fixed balloon and a first fixed pipeline; the esophagus physical stimulation balloon assembly comprises a second stimulation balloon and a second stimulation pipeline; the medicine stimulation assembly comprises a medicine injection pipe, the medicine injection pipe and the concentration sleeve are arranged inside and outside, and the lower end of the medicine injection pipe is provided with a medicine injection opening which extends outwards and is in butt joint with the outer side of the concentration sleeve. And the lower end part of the concentration sleeve is sequentially provided with an injection part which is butted and communicated with the medicine injection port, a second fixing part for fixing the second stimulation balloon and a first fixing part for fixing the first fixing balloon from top to bottom. By means of the medicine stimulation assembly and the esophagus physical stimulation balloon assembly, switching use or combined use of chemical stimulation and physical stimulation is achieved for modeling.

The present application relates to the field of food technology, and specifically discloses a composition for reducing gastroesophageal reflux in individuals, a preparation method and application thereof. The composition for reducing gastroesophageal reflux in individuals comprises lactadherin, medium-long chain triglyceride, human milk oligosaccharide and immunoglobulin G. The present application constructs a multi-target synergistic intervention mechanism combining physical protection, secretion regulation and tissue repair through the compounding of four core components, which can comprehensively block the occurrence and development of gastroesophageal reflux. Lactadherin constructs a physical barrier to reduce the risk of reflux dynamics from the source; MLCT precisely regulates gastric acid secretion, reducing chemical stimulation; HMO compound IgG strengthens the mucosal immune barrier and promotes damage repair. The above composition is applied to products for reducing gastroesophageal reflux in individuals, and multi-target synergistic effect is achieved, realizing the whole-chain closed-loop intervention from prevention, relief to repair, and significantly improving the clinical improvement effect.

The invention relates to the technical field of medical instruments, and discloses an airway and esophagus reflux protection monitoring system based on fluorescence imaging. The existing non-invasive monitoring method has the problems that equipment wearing is unstable, a light window is easy to pollute and the like, so that the monitoring accuracy is influenced. The system comprises an in-vitro imaging module, a fluorescent diaphragm and a necklace. The in-vitro imaging module is worn on the anterior neck of a patient to detect a fluorescence signal; the fluorescent diaphragm is swallowed by a patient, consists of a pepsin response layer and a pH sensitive indication layer, and can emit a fluorescent signal according to the pH value change of gastric juice; the air bag is arranged in the elastic band of the necklace, the connecting base can stably abut against the lower portion of the laryngeal knot after inflation, and the cleaning assembly is arranged on the connecting base and can automatically clean an in-vitro imaging module light window. The system realizes efficient and accurate monitoring of airway and esophageal reflux, provides a reliable basis for clinical diagnosis, and is suitable for monitoring airway and esophageal reflux conditions.

The present patent application relates to an oral composition comprising: palmitoylethanolamide, dry extract of Musa paradisiaca, dry extract of Zingiber officinale, a mixture containing a dry extract of Opuntia ficus-indica and a dry extract of Olea europaea, for use in the prevention and / or in the treatment.

The invention relates to the technical field of probiotic ferment powder, in particular to a preparation method of fruit and vegetable probiotic ferment powder for inhibiting gastroesophageal reflux, which comprises the following steps: mixing papaya powder, modified okra polysaccharide and acanthopanax polysaccharide, and inoculating lactobacillus plantarum for fermentation; mixing the probiotic microcapsules with fructo-oligosaccharide to obtain a probiotic component; hericium erinaceus beta-glucan and N-acetylneuraminic acid are mixed to obtain a mucous membrane repairing component; mixing calcium carbonate and bromelain to obtain an auxiliary functional component; and sequentially filling into a three-layer partition packaging bag to obtain the fruit and vegetable probiotic ferment powder for inhibiting gastroesophageal reflux. The microencapsulated probiotics can effectively resist gastric acid and cholate erosion through a multi-layer embedding structure, the survival rate and colonization ability of the probiotics in gastrointestinal tracts are improved, and the microecological balance of the gastrointestinal tracts can be repaired.

The invention relates to the technical field of medical instruments, in particular to an anti-reflux device and an introduction method and a recovery method thereof. The anti-regurgitation device comprises an implantation supporting assembly, the implantation supporting assembly comprises a first expandable supporting body, the first expandable supporting body is used for being implanted and embedded in the gastric fundus submucosa close to the cardia position and expands to generate a protrusion towards the inner side of the stomach to form an anti-regurgitation valve, and when the gastric peristalsis contracts, the protrusion generated by the first expandable supporting body moves towards the cardia position and blocks the pentenome, so that the anti-regurgitation valve is formed. The gastric contents are prevented from flowing back to the esophagus through the cardia; the leading-in pushing assembly is used for leading and implanting the implantation supporting assembly to a designated position and releasing the implantation supporting assembly, and the designated position comprises the gastric fundus submucosa close to the cardia position. According to the anti-reflux device and the introduction method and the recovery method thereof, the anti-reflux device is implanted into the body of a patient through a minimally invasive means, the effect of inhibiting gastroesophageal reflux is achieved, operation is easy, trauma is small, and recovery is fast.

The utility model discloses an instrument for implanting an anti-esophageal reflux filler through an endoscope channel, and relates to the technical field of medical instruments, the instrument comprises an extrusion type air inflation bag, a three-way valve, a sealant injector, an implantation tube, an air bag connecting tube and an adapter, a connecting air tube is arranged on the extrusion type air inflation bag, the three-way valve is arranged on the connecting air tube, and the sealant injector is arranged on the adapter. The implantation tube and the airbag connecting tube are connected with the three-way valve; the sealant injector is communicated to the connecting air pipe, the connector and the implantation pipe are integrally formed, a counter bore communicated with the implantation pipe is formed in the end face, away from the implantation pipe, of the connector, an annular air bag is arranged on the side wall of the counter bore, and the air bag connecting pipe is connected into the annular air bag. The filler is fixed through the connector, the filler is fed into an operation position from the endoscope channel through the implantation tube, the filler is expanded through the extrusion type inflation bag, and the filler can be injected and sealed through the sealant injector after expansion, so that the filler keeps expanding all the time; the problem that the anti-esophageal reflux filler cannot be implanted through an endoscope channel is solved.

The present patent application relates to an oral composition comprising: palmitoylethanolamide, dry extract of Musa paradisiaca, dry extract of Zingiber officinale, a mixture containing a dry extract of Opuntia ficus-indica and a dry extract of Olea europaea, for use in the prevention and / or in the treatment.

The present application relates to the field of traditional Chinese medicine preparation, and discloses a traditional Chinese medicine composition for relieving esophageal reflux cough, which comprises a first extraction component and a second extraction component, wherein the first extraction component is obtained by group extraction of perilla leaf and perilla stem, and the second extraction component is obtained by group extraction of rhizoma coptidis, prepared pinellia, evodia and licorice root.The two groups of raw medicinal materials are respectively decocted, filtered and concentrated to obtain the corresponding extraction components, which are then mixed to form the traditional Chinese medicine composition, which can be further prepared into oral liquid, granules, capsules, pills or powders.The present application is composed of six kinds of raw medicinal materials and prepared by group extraction and recombination, so that the composition is clear in composition and preparation process, and is suitable for preparing a medicine for relieving gastroesophageal reflux cough.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating gastroesophageal reflux cough and a preparation method thereof. The traditional Chinese medicine composition disclosed by the invention is constructed by carefully selecting a medicine formula under the guidance of a traditional Chinese medicine theory and clinical experience and through a compatibility theory of monarch, minister, assistant and guide of traditional Chinese medicines. In the traditional Chinese medicine composition, the inula flower has the effects of promoting blood circulation, removing stasis and turbidity, clearing the airway and removing phlegm and fluid retention, and the mangnolia officinalis has the effects of promoting qi circulation, removing food retention, calming adverse-rising energy and relieving asthma, and both serve as monarch drugs; the dried orange peel has the effects of regulating qi and removing stagnation, the poria cocos has the effects of tonifying spleen, eliminating dampness and phlegm and breaking up the source of phlegm, and the bulbus fritillariae cirrhosae has the effects of clearing heat and moistening lung and resolving phlegm and relieving asthma; the rhizoma atractylodis macrocephalae has the effects of invigorating the spleen, replenishing qi, eliminating dampness and inducing diuresis, and the endothelium corneum gigeriae galli has the effects of promoting digestion and invigorating the stomach and is an assistant and guide drug. The whole prescription is ordered in monarch and minister, focuses on pathogenesis, is rigorous in prescription, has the effects of relieving cough and asthma, clearing heat and moistening lung, and strengthening spleen and stomach, and treats both symptoms and root causes of cough.

The invention relates to the technical field of anti-regurgitation medical instruments, in particular to an active anti-regurgitation pressing and applying device which comprises a cover body, a binding belt, a circulating swing mechanism, an intelligent control module and a phase detection unit.The cover body is used for containing a driving mechanism and is fixed to the esophageal cardia area of the chest and abdomen of a user through the binding belt; the circulation swing mechanism is installed in the cover body, the intelligent control module controls the circulation swing mechanism, and in a massage mode, the anti-backflow massage head is driven to conduct circulation pressing from top to bottom in the chest and abdomen direction; in the positioning mode, the anti-reflux massage head stays at the position of the corresponding esophageal cardia, continuous positioning and pressure applying are carried out, and therefore esophageal reflux is prevented. The core purpose of the invention is to effectively press and cover the spray gate when a patient sleeps on the back on the premise of no medication and no operation so as to prevent gastric contents from flowing back to the esophagus or throat, so that the esophagus and throat reflux event is prevented.

The utility model discloses an anti-esophageal reflux filler, and relates to the technical field of medical consumables, the anti-esophageal reflux filler comprises a filling circular ring enclosed by a plurality of sections of balloon tubes, the balloon tubes are connected and formed through balloon tube joints, each balloon tube joint is provided with a first cylindrical end along the axial direction of the filling circular ring, and the first cylindrical end is provided with a second cylindrical end along the axial direction of the filling circular ring. Any first cylindrical end is provided with an inflation nozzle, and any balloon tube connector is provided with a second cylindrical end in the radial direction of the filling circular ring. The intestinal mucosa is annularly cut at the cardia, the surface mucosa is torn, the filling circular ring is placed on the inner side of the mucosa, meanwhile, the mucosa is ripped at the inflation nozzle to expose the inflation nozzle, the filling circular ring is wrapped on the inner side of the mucosa through the suture, and the balloon tube is inflated to expand and contract the cardia opening, so that the cardia opening is closed, and the cardia opening is closed. Therefore, the cardia opening size can be effectively and accurately controlled, and the purpose of effectively preventing reflux is achieved.