9 results about "Esophageal reflux" patented technology

The present application relates to the field of food technology, and specifically discloses a composition for reducing gastroesophageal reflux in individuals, a preparation method and application thereof. The composition for reducing gastroesophageal reflux in individuals comprises beta-defensin 1, lysozyme and lactoperoxidase. The present application constructs a multi-target synergistic intervention mechanism combining physical protection, secretion regulation and tissue repair through the compounding of four core components, which can comprehensively block the occurrence and development of gastroesophageal reflux. Lactadherin constructs a physical barrier to reduce the risk of reflux dynamics from the source; MLCT precisely regulates gastric acid secretion to reduce chemical stimulation; HMO complex IgG strengthens the mucosal immune barrier and promotes damage repair. The above composition is applied to products for reducing gastroesophageal reflux in individuals, and multi-target synergistic effect is achieved, realizing a full-chain closed-loop intervention from prevention, relief to repair, and significantly improving the clinical improvement effect.

The invention discloses a gastroesophageal reflux AI auxiliary typing method based on esophageal function and morphological characteristics, and belongs to the technical field of gastroesophageal reflux, a first index parameter is acquired, esophageal functional characteristics are evaluated by using a pre-training model according to the first index parameter, and a functional score is calculated; wherein the first index parameter comprises a high-resolution esophageal power index parameter and an esophageal pH-impedance combined index parameter; obtaining esophageal endoscopic image index parameters, and according to the esophageal endoscopic image index parameters, evaluating the severity of the foraminal hernia defect and cardia relaxation by using the deep learning convolutional neural network prediction model, and calculating a morphological score; comprehensively evaluating the severity of the gastroesophageal reflux according to the functional score and the morphological score, and completing the precise typing of the gastroesophageal reflux. The severity of esophageal dysfunction and morphological defect is effectively evaluated based on a comprehensive index evaluation system, and precise typing of gastroesophageal reflux disease is completed.

The invention discloses a medicinal moxa composition for preventing and treating chronic gastroenteritis combined with esophageal reflux, which comprises rhizoma atractylodis, wrinkled gianthyssop herb, fortune eupatorium herb and moxa, and can improve the symptoms of chronic gastroenteritis and esophageal reflux through the effects of strengthening spleen and stomach, eliminating dampness and dissolving turbidity, regulating qi and relieving pain and the like. Agastache rugosus is used for resolving dampness and regulating the middle warmer, fortune eupatorium herb is used for enlivening the spleen and promoting appetite, and the four medicines are compatible to form a balanced system for strengthening the spleen and stomach and eliminating dampness and turbidity. A plurality of volatile active ingredients of the medicinal moxa composition act on a plurality of key targets related to chronic gastroenteritis and esophageal reflux co-disease through moxibustion. Volatile components generated by combustion of the medicinal moxa composition directly act on esophageal mucosa and spleen and stomach areas, a'local-whole body 'synergistic effect mode is formed in combination with a warm effect and meridian stimulation, and a new thought and theoretical basis are provided for prevention and treatment of chronic gastroenteritis combined with esophageal reflux.

The present application belongs to the technical field of gastroscopy, and particularly relates to an auxiliary device for gastroesophageal reflux examination, which comprises an expandable sleeve assembly and a gastroscope assembly. The diameter of the expandable sleeve assembly can be changed. When the diameter of the expandable sleeve assembly is at a minimum value, the diameter of the expandable sleeve assembly is smaller than that of the gastroscope assembly. When the diameter of the expandable sleeve assembly is at a maximum value, the gastroscope assembly can be slidably inserted into the inside of the expandable sleeve assembly. The present application adopts a double-layer sleeve insertion structure. First, the expandable sleeve assembly in a contracted state with a smaller diameter is inserted into the esophagus to reduce the discomfort of the patient. Then, the expandable sleeve assembly is unfolded from the folded and contracted state to a hollow tube structure with a larger diameter. Then, the gastroscope assembly is inserted into the inside of the expandable sleeve assembly to complete the insertion of the gastroscope.

The utility model relates to an animal experiment device. The utility model discloses a gastroesophageal reflux chest pain modeling and treatment combined animal experiment device. The animal experiment device comprises a centralized sleeve, a fixed gastric sac assembly, an esophageal physical stimulation balloon assembly and a medicine stimulation assembly, the fixed gastric sac assembly comprises a first fixed balloon and a first fixed pipeline; the esophagus physical stimulation balloon assembly comprises a second stimulation balloon and a second stimulation pipeline; the medicine stimulation assembly comprises a medicine injection pipe, the medicine injection pipe and the concentration sleeve are arranged inside and outside, and the lower end of the medicine injection pipe is provided with a medicine injection opening which extends outwards and is in butt joint with the outer side of the concentration sleeve. And the lower end part of the concentration sleeve is sequentially provided with an injection part which is butted and communicated with the medicine injection port, a second fixing part for fixing the second stimulation balloon and a first fixing part for fixing the first fixing balloon from top to bottom. By means of the medicine stimulation assembly and the esophagus physical stimulation balloon assembly, switching use or combined use of chemical stimulation and physical stimulation is achieved for modeling.

The present application relates to the field of food technology, and specifically discloses a composition for reducing gastroesophageal reflux in individuals, a preparation method and application thereof. The composition for reducing gastroesophageal reflux in individuals comprises lactadherin, medium-long chain triglyceride, human milk oligosaccharide and immunoglobulin G. The present application constructs a multi-target synergistic intervention mechanism combining physical protection, secretion regulation and tissue repair through the compounding of four core components, which can comprehensively block the occurrence and development of gastroesophageal reflux. Lactadherin constructs a physical barrier to reduce the risk of reflux dynamics from the source; MLCT precisely regulates gastric acid secretion, reducing chemical stimulation; HMO compound IgG strengthens the mucosal immune barrier and promotes damage repair. The above composition is applied to products for reducing gastroesophageal reflux in individuals, and multi-target synergistic effect is achieved, realizing the whole-chain closed-loop intervention from prevention, relief to repair, and significantly improving the clinical improvement effect.

The utility model discloses an instrument for implanting an anti-esophageal reflux filler through an endoscope channel, and relates to the technical field of medical instruments, the instrument comprises an extrusion type air inflation bag, a three-way valve, a sealant injector, an implantation tube, an air bag connecting tube and an adapter, a connecting air tube is arranged on the extrusion type air inflation bag, the three-way valve is arranged on the connecting air tube, and the sealant injector is arranged on the adapter. The implantation tube and the airbag connecting tube are connected with the three-way valve; the sealant injector is communicated to the connecting air pipe, the connector and the implantation pipe are integrally formed, a counter bore communicated with the implantation pipe is formed in the end face, away from the implantation pipe, of the connector, an annular air bag is arranged on the side wall of the counter bore, and the air bag connecting pipe is connected into the annular air bag. The filler is fixed through the connector, the filler is fed into an operation position from the endoscope channel through the implantation tube, the filler is expanded through the extrusion type inflation bag, and the filler can be injected and sealed through the sealant injector after expansion, so that the filler keeps expanding all the time; the problem that the anti-esophageal reflux filler cannot be implanted through an endoscope channel is solved.

The present application relates to the field of traditional Chinese medicine preparation, and discloses a traditional Chinese medicine composition for relieving esophageal reflux cough, which comprises a first extraction component and a second extraction component, wherein the first extraction component is obtained by group extraction of perilla leaf and perilla stem, and the second extraction component is obtained by group extraction of rhizoma coptidis, prepared pinellia, evodia and licorice root.The two groups of raw medicinal materials are respectively decocted, filtered and concentrated to obtain the corresponding extraction components, which are then mixed to form the traditional Chinese medicine composition, which can be further prepared into oral liquid, granules, capsules, pills or powders.The present application is composed of six kinds of raw medicinal materials and prepared by group extraction and recombination, so that the composition is clear in composition and preparation process, and is suitable for preparing a medicine for relieving gastroesophageal reflux cough.

The utility model discloses an anti-esophageal reflux filler, and relates to the technical field of medical consumables, the anti-esophageal reflux filler comprises a filling circular ring enclosed by a plurality of sections of balloon tubes, the balloon tubes are connected and formed through balloon tube joints, each balloon tube joint is provided with a first cylindrical end along the axial direction of the filling circular ring, and the first cylindrical end is provided with a second cylindrical end along the axial direction of the filling circular ring. Any first cylindrical end is provided with an inflation nozzle, and any balloon tube connector is provided with a second cylindrical end in the radial direction of the filling circular ring. The intestinal mucosa is annularly cut at the cardia, the surface mucosa is torn, the filling circular ring is placed on the inner side of the mucosa, meanwhile, the mucosa is ripped at the inflation nozzle to expose the inflation nozzle, the filling circular ring is wrapped on the inner side of the mucosa through the suture, and the balloon tube is inflated to expand and contract the cardia opening, so that the cardia opening is closed, and the cardia opening is closed. Therefore, the cardia opening size can be effectively and accurately controlled, and the purpose of effectively preventing reflux is achieved.