58 results about "Esophageal reflux" patented technology

The present invention provides compositions for treatment of gastro-esophageal reflux disorders. The compositions include at least two of the following: (i) one or more digestive enzymes; (ii) one or more probiotics; and (iii) stevia. Also provided are processes for preparing the compositions useful for treatment of gastro-esophageal reflux disorders, and methods of treating subjects against gastro-esophageal reflux disorders, which include administering to a subject a therapeutically effective amount of the compositions of the present invention.

A system and method diagnoses esophageal reflux in a patient. A catheter includes a first pressure sensor configured to measure intra-abdominal pressure when the catheter is inserted into the stomach of a patient. A second pressure sensor is located proximal to the distal tip and configured to measure intra-thoracic pressure. A pH indicator is carried by the catheter body and configured to indicate that reflux has occurred in response to an involuntary reflex cough test. A processing device is configured to receive data regarding the first and second pressure sensors and regarding the pH indicator and process that data and assess if reflux is present during the involuntary epoch.

The invention provides a combined drug of pantoprazole and domperidone and in particular provides application of pantoprazole and domperidone to preparing combined injections for treating gastric ulcer, duodenal ulcer, gastro-esophageal reflux diseases or functional dyspepsia. The invention also provides the combined injections for treating gastric ulcer, duodenal ulcer, gastro-esophageal reflux diseases or functional dyspepsia, including different specifications of unit preparations, pantoprazole and domperidone for simultaneous, respective or successive administration and preparations prepared by pharmaceutically acceptable vectors. The weight ratio of pantoprazole and domperidone is 1:1-5:1, and the pantoprazole and domperidone contain excipients, stabilizing agents, etc. Through combined injection administration, the invention improves the bioavailability of pantoprazole and domperidone and ensures the treatment effects to be obviously better.

An infant formula for preventing gastro-esophageal reflux is disclosed comprising whey protein and/or casein, a galactomannan thickener, and a fermented milk-derived product.

This invention is a solid-liquid double chambers transfusion of injection bemegridethiazole, and it contains a bigger chamber and a smaller one. The smaller chamber is used to fill injection bemegridethiazole, while the bigger one is used to fill transfusion liquid. In the smaller chamber, each application unit contains 5mg-800mg sterile bemegridethiazole; In the bigger chamber, each application unit contains 100mg-50000mg isotonic conditioning agent, 0mg-4000mg sodium sulfite and 50mL-1000mL water for injection. The solid-liquid double chamber transfusion of injection bemegridethiazole is mainly used to short-term treat duodenum ulcer, gastric ulcer, pathological hyper stomach-acid secretion and reflux esophagitis. Closely before using this product, press the bigger chamber with hand and the two chambers will be dredged, rock back and forth to mix the medicine liquid even and intravenous drip. This production brings convenience to rescue personnel in clinical usage.

The invention relates to a stomach tube with core temperature detecting and esophageal reflux preventing actions. The stomach tube comprises a stomach tube body, a reflux-preventing air bag, a charging connector and a temperature sensor, wherein the reflux-preventing air bag is arranged at the periphery of the stomach tube body located at an esophagus, an airway is arranged in a liquid diet passage of the stomach tube body, the lower end of the airway communicates with the reflux-preventing air bag, the upper end of the airway is connected with an inflating pipe, the reflux-preventing air bagtemporarily blocks off the esophagus of a patient after being dilated so as to prevent gastric contents from refluxing; and the temperature sensor is composed of a temperature probe, a signal cable and a plug, the temperature probe is located on the stomach tube body corresponding to 1/3 to 1/2 of the esophagus so as to display a core temperature of the patient. According to the stomach tube disclosed by the invention, the internal temperature of the esophagus of the patient can be measured, meanwhile, normal inflow of fluid foods in a nasogastric tube is not affected, the detected core temperature of the esophagus is displayed through a monitor or display gage head, thus, medical personnel can learn the core temperature of the patient at any time, and diagnosis and treatment on diseases are facilitated.

The invention provides six-in-one anti-reversion particles and a preparation method thereof. The six-in-one anti-reversion particles are prepared from the following components in parts by weight: 600gof lily, 200 g of lindera aggregata, 200g of radix aucklandiae, 300g of vinegar-processed rhizoma corydalis, 300g of rhizoma cyperi, 180g of coptis chinensis, 60g of fructus evodiae and 240g of fructus aurantii. The invention also provides the preparation of the six-in-one anti-reversion particles. The preparation method comprises the following steps: S1) adding 5 times of water into the radix linderae, the radix aucklandiae, the rhizoma cyperi and the fructus aurantii, distilling for 3 hours, receiving distillate, standing, taking out a volatile oil layer for later use, and filtering a distilled water solution to obtain filtrate and medicine residues; S2) mixing the decoction dregs, lily, vinegar processed corydalis tuber, coptis chinensis and fructus evodiae, adding 8 times of water, decocting for three times, then filtering, combining filtrates, and standing overnight; and S3) taking out the supernatant of the combined filtrate. The six-in-one anti-reversion particles have a remarkable clinical effect on liver-stomach stagnated heat type esophagitis, have no recurrence and no side effect after drug withdrawal, and are convenient to popularize and use.

The present invention describes a mucoadhesive composition comprising chondroitin sulfate, xyloglucan and glycerol for use in the treatment and prevention of gastroesophageal reflux. It is also described a process for preparing such composition, a dosage form for its administration and a kit comprising the same.

The invention provides a traditional Chinese medicine composition for treating acid reflux, which comprises the following raw materials in parts by weight: 2-15g of radix curcumae, 2-10g of cape jasmine, 2-15g of bamboo shavings, 2-10g of pseudo-ginseng, 3-12g of ginger, 10-30g of pearl shell, 3-12g of light fermented soya bean, 5-20g of cuttlebone, 3-12g of honey-fried licorice root, 5-25g of loquat leaf, 3-15g of dried tangerine peel, 5-25g of dandelion, and 5-25g of jujube. The preparation method comprises the following steps: taking the raw material medicines for cleaning and removing impurities, adding water to decoct the materials and merging filtrates, concentrating and cooling the materials, adding ethanol to make an alcohol content of 20 to 80%, recovering the ethanol, and concentrating a supernatant into a thick paste for standby; and drying the thick paste to prepare a corresponding dosage form, wherein the dosage form includes a pill, a lozenge, pulvis, a powder, a particulate agent or a decoction bag. The traditional Chinese medicine composition can cure the acid reflux, treat the esophagitis, esophageal reflux and pharyngitis caused by the acid reflux, and can restorethe elasticity of the sphincter, simultaneously purify the stomach, and regulate and consolidate the gastric mucosa.

The invention relates to the technical field of medical auxiliary instruments, and particularly discloses an integrated premature infant body position auxiliary instrument. The integrated premature infant body position auxiliary instrument can be used for premature infants in neonatal wards or neonatal care rooms during hospitalization, and is a suitable tool provided for body position intervention of clinical nursing personnel; and the scope of developmental care of the premature infants is expanded. The integrated premature infant body position auxiliary instrument is particularly suitable for the premature infants during hospitalization, and the integrated component structure is beneficial for the premature infants to maintain flexion similar to intrauterine physiological flexion and support movement; apnea caused by bad body positions is avoided, and the risks of intracranial hemorrhage, gastroesophageal reflux and the like are reduced; and therefore, self-coordination and nerve development after birth are promoted.

The invention discloses a semi-solidified nutritional agent for solving the problem of enteral nutrition intolerance and a preparation method of the semi-solidified nutritional agent. The semi-solidified nutritional agent is prepared from the following components: 500-750 parts of carbohydrate, 135-200 parts of protein, 85-100 parts of fat, 10-50 parts of low-methoxy pectin, 0.1-2 parts of a vitamin compound and 5-80 parts of a mineral compound, wherein the mineral compound contains calcium hydrogen phosphate. After being brewed with warm water, the prepared semi-solidified nutritional agent is similar to a flowing liquid of a common beverage in an environment with a pH value of 7+/-0.2, so that a patient (such as a dysphagia patient with weakened tracheal closure muscle group control force) can take the nutritional agent orally conveniently, and the problem that a semi-solidified nutritional agent in the prior art is too high in viscosity and difficult to swallow is avoided; and after the liquid is drunk, calcium in calcium hydrogen phosphate is promoted to be separated out into calcium ions under the action of gastric acid, the calcium ions and free methoxyl groups in low-methoxyl pectin are subjected to bridging reaction, and an eggshell-shaped relatively stable ion binding type semi-solidified gel structure is formed, so that intestinal nutrition intolerance reactions such as gastroesophageal reflux, diarrhea and the like are inhibited.

The invention discloses a trachea cannula capable of performing esophageal drainage. The trachea cannula comprises a tube body, the tube body comprises a ventilation cavity and a drainage cavity whichextend along a main axis, and a far-end opening of the drainage cavity is located at the near end of the far-end opening of the ventilation cavity; the trachea cannula further comprises a first sleeve bag and a second sleeve bag which wrap the tube body, the first sleeve bag is located at the near end of the far-end opening of the ventilation cavity, and the second sleeve bag is located between the far end opening of the ventilation cavity and the first sleeve bag; and after the trachea cannula is inserted into the throat of a patient, openings in the near ends of the ventilation cavity and the drainage cavity are located outside the oral cavity of the patient, the first sleeve bag is used for sealing the glottis of the patient, the second sleeve bag is used for sealing the trachea of thepatient, and the drainage cavity communicates with the esophagus of the patient through a far-end opening to drain the esophagus. The trachea cannula provided by the invention can seal the trachea and the glottis of the patient at the same time, avoid esophageal reflux of the patient while guaranteeing that the trachea is well sealed, and meanwhile, can drain the esophagus and avoid esophagus blockage.

The invention discloses sodium alginate chewable tablets. The sodium alginate chewable tablets comprise the following components in parts by weight: 200-300 parts of sodium alginate, 50-300 parts of sodium bicarbonate, 150-300 parts of calcium carbonate, 30-300 parts of magnesium oxide, 50-300 parts of D-mannitol, 50-200 parts of polyethylene glycol 6000, 5-20 parts of hydroxypropyl methyl cellulose E50, 1-10 parts of peppermint essence, 1-3 parts of acesulfame potassium, 1-3 parts of aspartame, 5-100 parts of DC-grade xylitol, and 5-20 parts of magnesium stearate. The preparation method of the sodium alginate chewable tablets provided by the present application is simple, and the prepared chewable tablets can not only regulate gastroesophageal reflux and protect gastric mucosa, but also can supplement mineral elements calcium and magnesium at the same time, can also supplement zinc, and are suitable for a plurality of people; the sodium alginate chewable tablets are more convenient totake orally, and easy to carry; and the sodium alginate chewable tablets avoid the standard exceeding of aluminum elements and overdose of sodium elements, and can be used safely for a long time.