36 results about "Immune barrier" patented technology

The invention provides a skin barrier repairing complex, facial cream and a preparation method therefor. The skin barrier repairing complex comprises a composition for repairing skin barrier, hydroxylasiaticoside, deacidified carnosine, a glycyrrhiza inflata root extract, a radix scutellariae extract and a hamamelis extract, wherein the composition for repairing skin barrier comprises sea fennelcallus culture filtrate, Ectoin and a hydrolyzed red alga extract. The skin barrier repairing complex can achieve triple effects of simultaneously repairing cutin barrier, repairing immunologic barrier and strengthening microbiologic barrier; and the facial cream prepared from the skin barrier repairing complex is obvious in repairing effect and can be used for effectively improving hydrature of skin, increasing the content of hyaluronic acid in the skin, improving photoaging, helping cell saccharification reversing and reducing fine grain area.

The invention discloses a glycyrrhiza glabra L. extract composition with function of enhancing skin immune barrier, and a preparation method and an application thereof. The glycyrrhiza glabra L. extract composition consists of the following ingredients in parts by weight: 5-47.5% of glabridin, 30-50% of glycyrrhiza polysaccharide and the balance of glycyrrhizin. In the glycyrrhiza glabra L. extract composition, the glabridin, the glycyrrhiza polysaccharide and the glycyrrhizin are combined to generate a synergy effect so as to be favorable for eliminating side effects, including dry skins, irritation and the like, which may be generated when a product with a single whitening effect is used. The inhibition ratio of the glycyrrhiza glabra L. extract composition for tyrosinase can be 66.65%,the activity of the skin immune barrier is about 0.88, the composition has an excellent synergy effect on whitening and enhancing the skin immune barrier, and therefore, the skin is healthy, bright and moisturized. In addition, the light-colored glabridin is prepared through the purification of a specific molecularly imprinted resin, and therefore, the composition has a light color and high quality and is more suitable for preparing cosmetic products.

The present invention discloses an anti-enteritis grouper compound feed and a preparation method and a use method thereof. The compound feed includes the following components in percentages by weight: steam fish meal 13-18%, domestic fish meal 18-22%, fermented soybean meal 2-6%, sesame seed meal 17-20%, peanut kernel meal 3-7%, wheat flour 22-26%, blood meal 1-3%, earthworm powder 1-2%, soy lecithin 1-2%, sea fish oil 2-4%, calcium dihydrogen phosphate 1-3%, spirulina 0.5-1%, plantago depressa 0.2-0.5%, isatis tinctoria 0.2-0.5%, and premix 1-3%. The feed is finely prepared according to the growth characteristics and nutritional needs of groupers, has comprehensive nutrition and strong attractant, and can release growth potential of the groupers to the greatest extent. The Chinese herb medicines in the feed can improve the intestinal immune barrier and reinforce immune function.

The invention relates to a preparation method of micromolecular dendrobium officinale polysaccharide. A dendrobium officinale dried product is used as a starting raw material, and the micromolecularden drobium dendrobium officinale polysaccharide is obtained through a deep eutectic solvent and subcritical extraction. According to the preparation method of the micromolecular dendrobium officinale polysaccharide, the dendrobium officinale polysaccharide with the molecular weight smaller than or equal to 50 kD can be prepared, and the dendrobium officinale polysaccharide with the molecular weight smaller than or equal to 50 kD further has the advantages of being high in purity and high in extraction rate. The micromolecular dendrobium officinale polysaccharide with the molecular weight smaller than or equal to 50 kDa is small in molecular weight, high in purity, beneficial to skin absorption, capable of remarkably improving the skin immune barrier effect and good in anti-inflammatory effect.

The invention discloses a micropterus salmoides low-fish-meal-content compound feed capable of improving the intestinal health The micropterus salmoides low-fish-meal-content compound feed is formed by the following components in percentage by weight: 12-15% of fish meal, 5-12% of soybean protein concentrate, 10-20% of fermented soybean meal, 8-10% of enzymolysis soybean meal, 5-10% of chicken meal, 5-7% of corn protein powder, 5-8% of meat and bone meal, 8-12.38% of high gluten flour, 1-5% of fish oil, 3-7% of soybean oil, 0.2-1.0% of soybean lecithin, 0.2-1.0% of choline chloride, 0.5-1.0% of vitamin premix, 0.5-1.0% of mineral premix, 0.5 to 1.0 percent of calcium dihydrogen phosphate, 0.1 to 0.5 percent of L-lysine, 0.1 to 0.5 percent of L-methionine, 0.2 to 0.5 percent of taurine, 0.25 to 1.0 percent of tributyrin and 0.02 to 0.5 percent of alpha-ketoglutarate. The invention further provides a preparation method of the micropterus salmoides low-fish-meal-content compound feed. According to the invention, 70% of fish meal in an existing micropterus salmoides feed formula can be effectively replaced; the feed cost is remarkably reduced; and the growth performance of micropterus salmoides is fully guaranteed due to the fact that the intestinal health degree and the immune barrier function of micropterus salmoides are improved.

The invention discloses a multi-dimensional barrier repair composition. The composition comprises a functional compound, an osmotic equilibrium agent and a solvent; the functional compound comprises a functional component A which is a component capable of promoting keratinization envelope and tight junction protein expression, a functional component B which is a component capable of improving the self-moisturizing power of the skin, a functional component C which is a component capable of activating a PPAR receptor and strengthening a skin lipid barrier, a functional component D which is a component capable of regulating an immune barrier and relieving skin inflammation, and a functional component E which is a component capable of balancing the microecology of the epidermis; the osmotic equilibrium agent comprises one or more of lecithin and / or hydrogenated lecithin, maintains all the functional components to safely and effectively permeate to different sites of the skin barrier, and is an important component for enabling the composition to play a role; and the solvent comprises deionized water and an organic solvent. The invention also discloses a preparation method of the multi-dimensional barrier repair composition. The multi-dimensional barrier repair composition is capable of realizing effective co-dissolution of the functional compound, the osmotic equilibrium agent and the solvent in the composition.

The invention discloses a multifunctional antibacterial mold removal agent. The multifunctional antibacterial mold removal agent is prepared by grinding and mixing 80-90% of modified clay mineral, 0.5-5% activated carbon, 5-10% yeast nucleotide, 0.5-5% of allicin. The modified clay mineral of the invention is obtained by compound modification of betaine, a guanidine antibacterial agent and alkyl glycoside. The product has better detoxification ability and certain antibacterial properties, and has the functions of activating the immune system, improving the intestinal immune barrier, enhancingthe resistibility, protecting against the invading ability of the virus, and repairing body injury infected by the pathogen and the mould toxin. Through the multiple functions of antibiosis, detoxification and growth promotion, the production performance and feeding benefit of livestock and poultry are effectively improved.

The present invention discloses a lung cancer nutritious food and a preparation method thereof, and belongs to the technical field of nutritious foods. The lung cancer nutritious food contains nutrient components including proteins, fat, carbohydrate, vitamins, minerals, glutamine, arginine, lycopene, melatonin and apple essence. Under the premise of enough heat, the nutritious food in the invention is high in proteins, high in carbohydrate, low in fat and high in content of active functional substances, and targeted vitamins match with mineral element, so that the food can control the pathogenesis of patients from the aspects of oxidative stress and immunity, can improve the immune function of chemotherapy patients with advanced lung cancer, can protect the immune barrier of intestinal mucosa, and can regulate the mood and psychology of patients. Under the premise of effect, the product price is reduced through the element form selection and the simplification of collocation and salemode. The food can meet the nutritional requirements of patients as a single nutrient source, and also can be eaten together with other daily diets, thereby enriching the dietary types and eating modes and stimulating the eating interest of patients.

The invention discloses a probiotics composition and application thereof and a probiotics product. The probiotics composition comprises in parts by weight: 20 to 40 parts of parabacteroides distasonis, 20 to 40 parts of christensenella minuta and 20 to 40 parts of akkermansia muciniphila. By the probiotics composition containing the parabacteroides distasonis, the christensenella minuta and the akkermansia muciniphila in a specific proportion, intestinal permeability can be effectively reduced and the intestinal inflammation level is reduced, so that an intestinal physical barrier, chemical barrier and immunologic barrier can be effectively improved, and intestinal barrier function abnormalities caused by diet / metabolic diseases is obviously improved or relieved; and the probiotics composition can be widely used for preparing drugs, foods or health care products for regulating intestinal barrier functions. Moreover, the probiotics composition also can improve a case of body weight, blood glucose level or blood lipid level abnormalities caused by the metabolic disease.

Provided are conjugates of biomolecule and use thereof. The provided conjugates of biomoelculer contain a biomolecule and a functional moiety covalently linked to the biomolecule. The functional moiety contains a group that prevents the biomolecule from binding to its ligand or receptor, a cleavable linker arm that can be activated by proteolytic enzymes or can be acidically activated in a microenvironment of a disease, a linker arm that will automatically shed after the cleavable linker arm is cleaved, and a group that maintains or promotes the binding capacity of the biomolecule to its ligand or receptor. The conjugates of biomolecule can effectively reduce immunogenicity of the biomolecule, increase it's half-life, and breakthrough the immune barrier of an individual, reach a pathologicmicroenvironment and be activated and released in the pathologic microenvironment, selectively promoting proliferation or killing effect of T cells and the like in the tumor, thereby preventing on target off tumor toxicity or in the inflammatory microenvironment of autoimmune disease and achieving a low autoimmunity and high efficacy.

The invention relates to an anti-aging cream capable of beautifying breasts and bodies and enhancing skin immune barriers, and belongs to the technical field of skin care products, the anti-aging cream is prepared from the following raw materials in parts by weight: 48.4292-53.4592 parts of P1 phase, 11.1-12.1 parts of P2 phase, 1.3 parts of P3 phase, 0.2 part of P4 phase, 3.8008-6.4008 parts of P5 phase, 8.4-11.3 parts of P6 phase and 16.64-22.08 parts of P7 phase, in order to reduce the irritation of the cream to breasts, pure plant essence is mostly used as the raw materials, and the anti-aging cream is prepared from the following raw materials in parts by weight. The cream is prepared from medicinal plant raw materials such as a radix puerariae extract, a papaya fruit extract, a lucid ganoderma extract, a dioscorea villosa root extract, an oldenlandia diffusa extract, a cimicifuga racemosa root extract, a pseudo-ginseng extracting solution and a hydrolyzed soybean extract, so that the safety and the efficacy of the cream are improved; by adopting the tetrahydropiperine natural penetration enhancer, functional active matters can be better absorbed by the skin, and the skin care product has the characteristics of high safety, high mildness and the like.

The invention relates to a processing technology of ginkgo nuts sandwiched in red dates. The processing technology mainly comprises the following steps: selecting materials, blanching and peeling, debitterizing and protecting color, preparing a tea flavor marinade, dipping, cooking, and freeze-drying at low temperature. Removing pits of the red dates, and drying the red dates by microwave and hot air until the moisture content of a wet basis is not higher than 28%; and finally, combining the red dates with the ginkgo fruits, clamping the red dates with the ginkgo fruits, sterilizing and packaging. The ingredients are simple and only include the red dates and the gingko; the red dates and gingko are matched to be rich in nutrition and good in health-care effect; the red date polysaccharide enhances the intestinal immune barrier and plays a role in removing gingko poison; green tea and erythritol are used for pickling, so that the gingko is fragrant in mouth feel, low in calorific value, good in mouth feel and free of decayed tooth causing property; the red date and gingko juice is suitable for being eaten by people with hyperglycemia, hypertension, middle-aged and elderly people and people paying attention to healthy diet, and can be widely applied to the field of red date and gingko.

The invention discloses an efficient and high-activity mouse intestinal epithelium and immune cell separation and extraction method, and belongs to the technical field of biological cell extraction. The intestinal epithelial cells, the interepithelial immune cells and the intestinal intrinsic layer immune cells separated and extracted by the method are high in yield and high in activity, and can be widely applied to related researches of intestinal mechanical barriers and immune barriers. Compared with the existing method, the separation and extraction steps are simple, the consumed time is greatly reduced, the single cell separation and purification can be completed within about 3.5 hours generally, and the subsequent research can be more efficiently carried out.

The invention discloses an administration method for protecting bacteriophage activity and application thereof. The method utilizes host bacteria of the bacteriophage to protect the bacteriophage, thereby enhancing resistance of the bacteriophage. The method aims to help the bacteriophage to break body immunization barriers, so that the bacteriophage can complete a first propagation under protection of the host bacteria and release numerous filial generation bacteriophages and further singularly invade and crack infectious bacteria. The method of the invention can be applied to bacteriophage therapies of infections of all parts and organs of body caused by prokaryotic and eukaryotic cell microbes. The invention reduces interference of body resistance on the bacteriophage therapy, amplifies and magnifies treatment dosage and treatment effect of the bacteriophage, and provides a new, practical and effective administration method for enforcing clinical bacteriophage treatment on microbe infectious diseases.

The invention discloses an anti-drug resistance antidiarrheal microbial preparation which comprises the following components: 4-10 parts of montmorillonite pretreatment substance, 0.1-3 parts of bacteriophage liquid, 0.5-5 parts of lactobacillus acidophilus powder and 0.1-3 parts of streptococcus faecalis powder, wherein the montmorillonite pretreatment substance is prepared by the following steps: adding water into 60-80% of montmorillonite nano powder, 10-30% of liquorice and 5-15% of pericarpium granati and mixing; boiling for 0.5-2 hours; drying the mixture; and finally, grinding the mixture into powder. Correspondingly, the invention also discloses a method for preparing the microbial preparation. In the invention, the bacteriophage in the microbial preparation easily breaks through the immune barrier and cooperates with the probiotics and herbal medicine components in the preparation to prevent and treat the infected intestinal diseases caused by corresponding prokaryotic and eukaryotic cell type microorganisms in the body and to prevent and treat allergic diarrhea; and moreover, the generation of animal-source drug-resistant bacteria can be delayed.

The invention discloses an automatic vaccine inoculation cabin system and a control method, the system comprises an automatic vaccine inoculation cabin, a server and a user terminal, the user terminal uploads vaccinator information to the server and generates a corresponding two-dimensional code; the automatic vaccine inoculation cabin comprises a cabin body, a front cabin door, a rear cabin door, a seat, an information collecting and recording module, an automatic injection module, a human body induction module, a disinfection and ventilation module and a main control module, the information collecting and recording module collects and records inoculator information and temperature information through a two-dimensional code and uploads the information to a server, and the automatic injection module grabs arms of an inoculator; and injecting the vaccine into a human body. According to the system, automatic inoculation and rapid information recording can be realized through the automatic injection module and the information collecting and recording module, an inoculation information chain is perfected, the workload of workers is reduced, and an immune barrier is established more efficiently. The efficient ventilation and disinfection module can block cross infection of an inoculation site, and the safe and efficient inoculation and disinfection requirements of an inoculator are met.

The invention provides a plant nutrition compound skin care composition and a preparation method and use thereof, and relates to the technical field of cosmetics. The skin care composition is prepared from the following raw materials in parts by weight: 1-4 parts of a spiraea salicifolia flower extract, 1-3 parts of a mulberry root extract, 2-5 parts of a sedum sarmentosum extract, 1-6 parts of a herba houttuyniae extract and 7-10 parts of a humectant. The skin care composition has advantages of resisting and relieving allergy, calming the skin and enhancing an immune barrier of the skin.

The invention discloses rumen lactobacillus capable of protecting intestinal barriers and application, and belongs to the technical field of biology. The rumen lactobacillus provided by the inventioncan significantly reduce the disease activity index of DSS-induced intestinal damage mice, and compared with model group mice, the rumen lactobacillus CCFM1140 intervention group mice have significantly reduced tissue damage, reduced concentrations of pro-inflammatory cytokines TNF-alpha, IL-1beta and IL-17, and up-regulated concentrations of anti-inflammatory cytokines IL-10. The strain has the functions of improving intestinal tract mechanical barriers, immune barriers and biological barriers, can be used as a main component of a probiotic preparation, and has a wide market prospect.

The invention relates to an application of cubilose for preparing a medicine for protecting an intestinal mucosal immune barrier. By utilizing the medicine of the application, the normal proportion of lymphocytes in intestinal Peyer's patches can be recovered, secretion of intestinal sIgA can be promoted, the intestinal mucosal immune barrier can be protected, and damage of the intestinal mucosal immune barrier caused by chemotherapeutics can be effectively relieved.

The invention discloses a foot ointment for treating diabetic foot and a preparation method thereof, belonging to the technical field of treatment of diabetic complications. The foot ointment is prepared from the following components in parts by mass: 40-60 parts of pearl powder, 8-8 parts of notoginseng 16 parts, 7~12 parts of coptis, 8~15 parts of scorpion, 7~13 parts of centipede, 9~14 parts of angelica, 8~14 parts of raw Aconitum, 10~15 parts of Scutellaria baicalensis, 8~13 parts of Cortex Phellodendri, 28 parts of raw gypsum ~34 parts, ginseng 13~18 parts, castor oil 27~31 parts, kansui 13~18 parts, vaseline 45~60 parts, black soybean distillate 29~34 parts, eucalyptus oil 28~31 parts, borneol 13~16 parts 3~6 parts of glycerin, 27~33 parts of hibiscus bark extract, 4~8 parts of licorice extract, 8~12 parts of zedoary oil, 40~50 parts of yellow dan, improve skin immune barrier, reduce inflammation and make ulcer surface Healing, the sores gradually shrink, the ulcer surface disappears, and finally heals.

The invention discloses a composition containing Ectoine, adenosine, coenzyme Q10, glycosylglycerol, hydrogenated lecithin and sodium hyaluronate and a preparation method and application of the composition. According to the composition, all the components are reasonably proportioned and are synergistic, so that the cell energy and the cell repairing capability are enhanced, the metabolism of skin is improved, the activity of regenerated skin cells is activated, the defense capability of skin cells is improved, harmful invasion factors are isolated outside the skin by enhancing cell energy and activity, repairing a cutin barrier, and improving a immune barrier from inside to outside of the skin, to construct a complete and healthy skin defense line , so that various skin problems are fundamentally solved. The composition disclosed by the invention can be applied to the aspects of enhancing the cell energy and improving the skin resistance, or can also be applied to various skin care products.

The invention discloses a formula of a medicine for treating rheumatic bone disease, and relates to the field of medicine. The formula consists of 20-30g of bird's nest, 10-20g of radix paeoniae alba, 5-15g of radix aconiti preparata, 10-20g of Chinese angelica, 20-30g of rehmanniae praeparatum, 20-30g of radix cyathulae and 10-20g of liquorice root. The medicine disclosed by the invention has functions of relaxing sinew and dredging collaterals, invigorating spleen and removing impediment, tonifying kidney, strengthening bones and generating marrow, replenishing qi and nourishing blood, reinforcing healthy qi and nourishing yin, reconstructing joints and serving as immune barrier for kidney, thus balancing the physiological functions of a human body, enhancing the disease resistance and immunity of the human body, repairing the functions of bone joints and reversing the deformed or abnormal bone joints and osteonecrosis.

The invention provides a skin barrier repairing complex, facial cream and a preparation method therefor. The skin barrier repairing complex comprises a composition for repairing skin barrier, hydroxylasiaticoside, deacidified carnosine, a glycyrrhiza inflata root extract, a radix scutellariae extract and a hamamelis extract, wherein the composition for repairing skin barrier comprises sea fennelcallus culture filtrate, Ectoin and a hydrolyzed red alga extract. The skin barrier repairing complex can achieve triple effects of simultaneously repairing cutin barrier, repairing immunologic barrier and strengthening microbiologic barrier; and the facial cream prepared from the skin barrier repairing complex is obvious in repairing effect and can be used for effectively improving hydrature of skin, increasing the content of hyaluronic acid in the skin, improving photoaging, helping cell saccharification reversing and reducing fine grain area.

The invention discloses a composition for protecting and repairing a skin barrier as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The composition for protecting and repairing the skin barrier comprises the following components: sea buckthorn seed oil, meadowfoam seed oil, prinsepia utilis royle oil, silybum marianum seed oil, perilla seed oil and an antioxidant. Experiments find that the composition composed of the five vegetable oils according to a certain ratio can resist external pollution, and comprehensively protect and repair skin from five dimensions such as a skin immune barrier, a microorganism barrier, an anti-oxidation barrier, a light protection barrier and a moisturizing barrier, so that the skin can regain brilliance.

The invention discloses a traditional Chinese medicine aromatic bag for treating infantile recurrent respiratory tract infection. The traditional Chinese medicine aromatic bag is prepared from the following components in parts by weight: 3-9 parts of honeysuckle, 2-6 parts of dandelion, 1-5 parts of poria cocos, 3-9 parts of platycodon grandiflorum, 4-12 parts of radix saposhnikoviae, 2-6 parts of schizonepeta, 1-5 parts of raw liquorice, 4-12 parts of ephedra, 2-6 parts of rhizoma atractylodis, 3-9 parts of chrysanthemum, 1-5 parts of almond and 3-9 parts of cassia twig. According to the traditional Chinese medicine sachet, the traditional Chinese medicine sachet has a good effect on treating children recurrent respiratory tract infection, the use method is simple, compared with a traditional medicine feeding mode, operation is simple and easy, the phenomenon that children refuse to take medicine can be effectively avoided, the traditional Chinese medicine sachet also has a good effect on prevention of cured respiratory tract infection, and the traditional Chinese medicine sachet is worthy of popularization and application. Intrusion of respiratory viruses can be effectively inhibited, the immune barrier of respiratory tract infection resistance is improved, respiratory tract mucosa is adjusted, and the immunity of respiratory tract infection resistance of children is enhanced.

The invention relates to a premixed feed having an antiviral effect for livestock and poultry and a preparation and feeding method thereof. The premixed feed comprises, by weight percentage, 0.8-2.5%of multivitamins, 0.6-1.5% of taurine, 2-10% of a Chinese herbal medicine extract and the balance sucrose. The premixed feed prepared according to a formula is matched with the feeding method and caneffectively inhibit virus and bacterial infection, improve the immunity of various organs of the whole body of the livestock and poultry, build an immune barrier and reduce the morbidity. The effectsof resisting stress and oxidation and realizing direct inhibition and two-way regulation are achieved, and the feed is comprehensive in efficacy, soluble in water and convenient to use; the quality ofanimal products is improved, the fattening period is shortened, and the daily weight gain is increased; the feed quality is improved, the appetite of animals is improved, digestion and absorption arepromoted, the feed utilization rate is increased, and the feeding cost is reduced.