194 results about "Reactive oxygen radicals" patented technology

The invention discloses application of a multifunctional carbon quantum dot taken as a fluorescent whitening agent in the fields of spinning printing and dyeing, washing agents, papermaking, plastics, leathers or coatings and the like. The carbon quantum dot disclosed by the invention has the advantages of wide application field, good whitening effect and good light resistance, is innoxious and environmentally friendly, can be applied to the fields of spinning printing and dyeing, washing agents, papermaking, plastics, leathers or coatings and the like, and can generate unforeseeable technical effect because the carbon quantum dot can generate active oxygen free radicals under the condition of illumination, wherein the unforeseeable technical effect is as follows: the bacteria attached to the surfaces of spinning printing and dyeing materials, the washing agents, paper sheets, the plastics, the leathers or the coatings and the like can be effectively killed after the spinning printing and dyeing materials, the washing agents, paper sheets, the plastics, the leathers or the coatings and the like which are doped with the carbon quantum dot absorb ultraviolet light.

The invention aims to provide an active oxygen free radical sensitive cyclodextrin material as a drug delivery carrier. The chemical structure of the cyclodextrin material is disclosed in the specification, wherein n is equal to 6, 7 or 8 which are respectively corresponding to active oxygen free radical sensitive alpha-cyclodextrin, beta-cyclodextrin or gamma-cyclodextrin material; R is -H or disclosed in the specification; and the glucose unit of each cyclodextrin molecule at least has one R group disclosed in the specification. The invention also provides a preparation method of the cyclodextrin material.

The invention belongs to the field of biomedicine and particularly discloses the application of gold nanocluster in preparation of a drug for treating tumors. Experimental study discovers that the gold nanocluster can enter cells by virtue of receptor-mediated endocytosis, form endosome and fuse with lysosome so as to deposit in the lysosome. Under light conditions, a photo chemical reaction is carried out on the surface of the gold nanocluster, production of reactive oxide species (ROS) is triggered, apoptosis is initiated, and the ROS can further attack cytoskeleton to cause cytoskeleton fracture and functional damage. The invention firstly proposes that the gold nanocluster can serve as a novel nano-drug to be used for treatment of tumors. As the nano-drug, the gold nanocluster is excellent in biocompatibility and high in safety. As an inert metal, the gold has excellent biocompatibility, and small interference on normal physiological activities of organisms/cells and low toxicity;the gold nanocluster has an effect of killing the tumors under specified conditions only, and is high in using safety.

The invention relates to a method for raw water preoxidation with an electrochemical preoxidation device, which includes a hydrogen peroxide electroproduction appratus and a hydroxyl free radical generating apparatus. Raw water flows through the hydrogen peroxide electroproduction apparatus taking a graphite felt electrode as a negative electrode and a reticular ruthenium-iridium plated titanium electrode as a positive electrode, and air is introduced from the bottom of the apparatus for electrolysis to produce hydrogen peroxide and other active oxygen free radicals, so that the bacteria, turbidiness, odor and smell and the like of a water body can be eliminated. If the raw water has a high organic substance content and turbidiness, the water can further flow through the hydroxyl free radical generating apparatus. With no need for any additional chemical reagent, the device and method of the invention can reduce the total bacteria, turbidiness, odor and smell of the raw water, and avoid the problem of generation of a large number of disinfection by-products from prechlorination, thus being able to serve as a preoxidation technology for a water supply plant or a water treatment means for other purposes.

Glossy ganoderma as a traditional Chinese medicine is called immortal grass since ancient times and known as the ability to treat various diseases; a pair of lingzhiol A optical enantiomers is purified from ganoderma lucidum, and the lingzhiol A optical enantiomers have obvious effects on inhibiting rat renal mesangial cell strains induced by high glucose to generate reactive oxide species, IL-6, fibronectin and IV type collagen, and also can obviously inhibit the phosphorylation of the renal tubular epithelial cell Smad3 induced by TGF-beta1, so that the application prospect of the compound in preparation of medicines for treating diabetic nephropathy and chronic nephropathy is shown.

Embodiments of the invention generally provide methods for cleaning a UV processing chamber. In one embodiment, the method includes flowing an oxygen-containing gas through a plurality of passages formed in a UV transparent gas distribution showerhead and into a processing region located between the UV transparent gas distribution showerhead and a substrate support disposed within the thermal processing chamber, exposing the oxygen-containing gas to UV radiation under a pressure scheme comprising a low pressure stage and a high pressure stage to generate reactive oxygen radicals, and removing unwanted residues or deposition build-up from exposed surfaces of chamber components presented in the thermal processing chamber using the reactive oxygen radicals.

The invention is the pioneering invention in the paper making field, which is characterized by cutting kenaf is into small segments of 2-5cm, soaking the small segments and rolling to form fiber bundles by a thread rolling machine, conveying the fiber bundles to a stainless steel vessel, adopting potassium-based hydrogen peroxide and oxygen to generate hydroxyl free radical and active oxygen free radical with the catalysis of ultraviolet light at the temperature of 80 DEG C, discarding chromophoric group of lignin to form coarse pulp with whiteness being 60%ISO-85%ISO, then forming clean pulp without chlorine or contamination through discongesting, fine grinding, screening and deslagging. The invention is used for producing high-grade paper products such as cigarette paper, decorating paper, currency paper, and the like, and completely solves the two problems of serious contamination from paper making and harm to human body from chloride ion.

The invention discloses a 3D flexible electrode or a 3D flexible catalyst as well as a preparation method and an application thereof. The preparation method comprises steps as follows: (1) a zinc oxide crystal array grows on carbon fibers; (2) a carbon fiber/zinc oxide@polydopamine composite material is synthesized; (3) a carbon fiber/zinc oxide@polydopamine-precious metal composite material is prepared. The method can further comprise the step as follows: (4) a carbon fiber@nitrogen-doped carbon tube-precious metal composite material is prepared. The whole process design of key preparation processes, the reaction condition of each step and the like are improved, the problems of limited carbon fiber surface area and low loading nanomaterial activity can be effectively solved, the prepared carbon fiber/zinc oxide@polydopamine-precious metal composite material and the prepared carbon fiber@nitrogen-doped carbon tube-precious metal composite material serve as the 3D flexible electrode and the 3D flexible catalyst, have a good catalytic effect and are particularly applicable to detection of reactive oxygen free radicals in cancer cells.

The invention relates to a clean pulping method of linters, which is a pioneering invention belonging to the field of environmental protection. The clean pulping method is technically characterized that the linters are conveyed into a stainless steel container I after the processing steps of cotton opening, dust removing and impurity removing; potassium base peroxide (details are disclosed in the patent of the utility model of 200620138146.3) manufactured by an ionic membrane exchanger on the spot is added for pretreatment; sundries such as waxiness, colloid, sugar, and the like in a slurry are cleared so as to improve the whiteness of the slurry to 60 percent ISO; the slurry is conveyed to a stainless steel container II, and peroxide and oxygen are added; under the catalysis of ultraviolet light and the temperature of 80 DEG C, hydroxyl free radicals and active oxygen free radicals are generated so as to break away chromophore groups and auxochromic groups in the slurry; hemicellulose and lignin in the slurry are further degraded, the polymerization degree of fibers is reduced, and the whiteness of the slurry is improved to 85 percent ISO; the slurry is conveyed to a stainless steel pressure container, and the temperature in the stainless steel pressure container is risen to 120 DEG C and preserved for 100 minutes so as to ensure that the polymerization degree is reduced to 50+/-10; and through the processing steps of screening, deslagging, press-rolling and drying, qualified cotton pulp is manufactured. The whole process of the clean pulping method has no black liquor, no emission of waste water and waste slag and no poisonous and harmful substances.

The invention discloses methods and systems for conductively coupling the body and more specifically the bare feet of an animal or human body to the earth in situations where conductive contact with the earth is otherwise impossible, such as inside a home or other building or in a bed. Various embodiments of the invention allow earth's mobile surface charge of free electrons to flow from the earth to the body, (similar to that which occurs naturally when an animal or human is standing barefoot on the earth), for the purpose of neutralizing excess or residual immune system-produced reactive oxygen species free radicals that cause physiological deficiencies and disturbances in the body such as acute or chronic inflammation.

The invention relates to a near infrared fluorescence probe capable of simultaneously detecting hydrogen peroxide and peroxynitrite anoin as well as a synthetic method and application thereof. The near infrared fluorescence probe is formed by binding near infrared cyanine fluorescent dyes, a mitochondrial targeted group triphenylphosphonium salt and diselenium constitutional units by virtue of chemical covalent bonds. An excitation-emission wavelength is in a near infrared region, the detection sensitivity of the method can be improved, and the detection limit of the testing method is reduced.The near infrared fluorescence probe is expected to realize differentiated simultaneous quantitative determination of H2O2 and ONOO- in cells, and has a certain theoretical significance for dynamically observing and researching production, metabolism and mutual transformation of reactive oxide species in living mitochondria as well as process pathways and mechanisms that dynamically damage livingorganisms. Moreover, a useful tool is provided for detecting indexes in aspects of cell functions including cell activity, cytotoxicity, cell apoptosis, cell membrane potential, cell cycle and the like.

The invention discloses an application of Chinese angelica polypeptide with effects of resisting oxidization and delaying ageing in preparation of food, particularly of health food, and further discloses a preparation method of the Chinese angelica polypeptide. The preparation method is simple and easy to implement, safe and non-toxic, stable and efficient, and is suitable for industrial production. In vitro, the Chinese angelica polypeptide has a characteristic of a certain hydroxyl radical clearance rate, which means that the Chinese angelica polypeptide has capacity of clearing active oxygen; at an integral animal level, an oxidative stress model and an ageing-associated model are used to perform a test, the test result discloses that the survival time of caenorhabditis elegans under an oxidative stress condition can be remarkably prolonged, the lipofuscin level in the caenorhabditis elegans is reduced, average lifetime of the caenorhabditis elegans is prolonged; under the oxidative stress condition and the ageing condition, the Chinese angelica polypeptide can be used for realizing remarkable anti-oxidization and ageing delaying effects by lowering the reactive oxide species (ROS) in vivo and lowering the content of lipid peroxide.

The invention relates to the field of animal husbandry and veterinary medicines, and particularly provides a preparation capable of improving the cow conception rate, as well as a preparation method and an application of the preparation. An effective component of the preparation comprises melatonin with the concentration of 10<-3> to 10<-1>mol/L and vitamin E (Ve) with the concentration of 10<-6> to 10<-4> mol/L. The animal experiment proves that when in-vitro injection of the preparation is carried out on breeding at the same time, the damage of reactive oxygen species (ROS) to quality of ovum can be reduced, and egg-sperm binding is promoted to achieve fertilization. According to the preparation, the cow conception rate can be effectively improved, and the reproduction efficiency of cows is improved.

There is provided a C12A7 compound capable of selectively and reversibly clathrating X⁻ ions, such as active oxygen radicals, with improved controllability. The C12A7 compound clathrating OH⁻ ions and On⁻ at a concentration of 2×10¹⁹ cm⁻³ or less can be prepared by subjecting a mixed material containing Ca and Al to a solid phase reaction at a firing temperature not lower than 1200° C. and lower than 1449° C. in a dry oxygen atmosphere having an oxygen partial pressure of 0.1 atm or more and a water vapor partial pressure of 10⁻³ atm or less, keeping the resultant product at a temperature of 1200° C. or higher, and cooling rapidly. The C12A7 compound is heat-treated to clathrate OH⁻ ions at a concentration of 2×10¹⁹ cm⁻³ or less, and On⁻ at a high concentration of more than 2×10¹⁹ cm⁻³. The compound can reversibly clathrate or release On⁻ ion radicals through the elevation or lowering of the temperature thereof in a temperature range of 300 to 850° C. The compound is useful for an oxidation catalyst, an anti-bacterial agent, an ion conducting material, an electrode for a solid-electrolyte fuel cell, and the like.

The invention discloses the application of pristimerin to preparation of an inflammatory cytokine inhibitor, in particular application of the pristimerin to treatment of symptoms related to excessive secretion of TNF-alpha, IL-6 and IL-8, and/or application of pristimerin to the aspect of active oxygen free radical inhibitors.

The invention belongs to the field of assisted reproduction and in particular relates to an in vitro fertilization culture solution and a preparation method thereof. A composition used for preparing the in vitro fertilization culture solution comprises resveratrol, reduced glutathione and lecithin, wherein a molar ratio of the resveratrol to the reduced glutathione to the lecithin is (5-50):(100-250):(8000-12000). The in vitro fertilization culture solution disclosed by the invention can achieve effects of providing a stable fertilization condition, removing reactive oxygen produced by cells and reactive oxygen free radicals produced by sperms in the motion process, reducing damage of the reactive oxygen to the sperms and ovum, improving the sperm motility, repairing cellular damage and improving the rate of fertilization and blastocyst formation rate, and the blastocyst formation rate is more than or equal to 90%.