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81 results about "Acute injury" patented technology

Bacterial cellulose (BC) based antibacterial dry film applied to acute injury as well as preparation method and application thereof

The invention relates to a bacterial cellulose (BC) based antibacterial dry film applied to acute injury, comprising the following components: a BC dry film and an antibacterial agent, wherein the drug loading rate of the BC based antibacterial dry film is 0.0114-0.2027mg/cm2. A preparation method of the BC based antibacterial dry film comprises the steps of: after implanting production strains of the BC into a seed culture medium for propagation culture, transplanting the strain to a fermentation medium for static culture, obtaining a BC wet film for soaking and water-bath, cutting the wet film into sheets for drying, dipping the sheets in a prepared antibacterial agent solution for the secondary drying to obtain the BC based antibacterial dry film. In the invention, the BC based antibacterial dry film has the advantages of light and soft texture, good biocompatibility, high hygroscopicity, good air permeability, durable antibiotic property and the like; in addition, the preparation method is simple, convenient and easy in operation and has low cost; in the practical application process, the BC based antibacterial dry film can be sheared into any shapes, is not adhered, does not irritate to skin, can be rapidly degraded in the environment after being abandoned, and can be taken as a green and environment-friendly functional antibacterial dressing.
Owner:DONGHUA UNIV

Flexible neural electrode and implantation method of flexible neural electrode

The present invention discloses a flexible neural electrode and an implantation method of a flexible neural electrode. The flexible neural electrode comprises a flexible substrate, a flexible insulation layer and a conductive layer and a magnetic material layer which are located between the flexible substrate and the flexible insulation layer. The conductive layer comprises at least one conductivewire, each conductive wire comprises one interconnection wire and one record site and one welding spot which are respectively located at two ends of each interconnection wire; the magnetic material layer comprises a plurality of magnetic material portion which are in one-to-one correspondence with the interconnection wires of a first portion; at least one through hole is formed on the flexible insulation layer, the through holes are in one-to-one correspondence with the record sites, and the through holes penetrate the flexible insulation layer to expose the corresponding record sites. The flexible neural electrode has magnetism and can be implanted to the cerebral cortex under the traction effect of the magnetic field force so as to allow the implantation of the flexible neural electrodenot to influence the large acute injury of the brain tissue.
Owner:THE NAT CENT FOR NANOSCI & TECH NCNST OF CHINA

Injection for curing acute lung injury and acute respirotary distress syndrome

The injection preparation for treating acute lung injury and acute respiratory distress syndrome is bacteria-free freeze dried powder for injection with Sivelestat as active component, stuffing frame agent, co-solvent and pH regulator. It has improved water solubility of Sivelestat and improved medicine stability.
Owner:HONGYI SCI & TECH CO LTD NANCHANG

Cryptotanshinone for preventing and treating pulmonary fibrosis and application thereof

The invention relates to the technical field of medicines, and particularly relates to cryptotanshinone for preventing and treating pulmonary fibrosis and an application thereof. The cryptotanshinone (I) is quinone diterpene extracted from the root part of salviae miltiorrhizae; the modern pharmacological research shows that the cryptotanshinone has a bacteriostatic effect, an anti-inflammatory effect and a hormone-like pharmacologic effect, and is clinically used for treating myocardial fibrosis, lung acute injury and arthritis, can be used for preventing and / or treating a pulmonary fibrosis disease, can also be used for preparing medicines for reducing body weight of a pulmonary fibrosis rat, a lung coefficient and the content of hydroxyproline in tissue and can be used for preparing the medicines for reducing the content of IL-1beta, IL-6 and TNF-alpha in a bronchoalveolar lavage liquid and the medicines of effecting the pathogeny structure of pulmonary fibrosis tissue of the rat. The formula (I) is as shown in the specification.
Owner:SUN YAT SEN UNIV +1

Bacterial cellulose based antibacterial dry film applied to acute injury as well as preparation method and application thereof

The invention relates to a bacterial cellulose (BC) based antibacterial dry film applied to acute injury, comprising the following components of a BC dry film and an antibacterial agent, wherein the drug loading rate of the BC based antibacterial dry film is 0.0114-0.2027mg / cm<2>. A preparation method of the BC based antibacterial dry film comprises the steps of: after implanting production strains of the BC into a seed culture medium for spreading cultivation, transplanting the strains to a fermentation medium for static culture, obtaining a BC wet film for soaking and water-bath treatment, cutting the wet film into sheets for drying, dipping the sheets in a pre-prepared antibacterial agent solution for secondary drying to obtain the BC based antibacterial dry film. In the invention, the BC based antibacterial dry film has the advantages of light and soft texture, good biocompatibility, high hygroscopicity, good air permeability, long-lasting antibiotic property and the like; in addition, the preparation method is simple, convenient and easy in operation and has low cost; in the practical application process, the BC based antibacterial dry film can be sheared into any shape, is not adhesive, has no irritation on skin, can be rapidly degraded in the environment after being abandoned, and can be taken as a green and environment-friendly functional antibacterial dressing.
Owner:DONGHUA UNIV

Pedestrian protection safety system for vehicles and control method

InactiveCN106184108AReduce the level of severe damagePedestrian/occupant safety arrangementSafety netImaging processing
The invention discloses a pedestrian protection safety system for vehicles and a control method, and relates to the field of vehicle safety. The pedestrian protection safety system comprises an image acquiring device, an image processing device, a safety net and a controller. The image acquiring device is used for acquiring the images in front of the vehicles. The image processing device is used for judging whether pedestrians exist or not in front of the vehicles. The safety net is surrounds a front compartment of the vehicles and the side face of a passenger compartment after being unfolded. The controller is arranged to control the safety net to be unfolded when it is judged that pedestrians exist in front of the vehicles. The invention further provides the corresponding control method. The safety net is arranged, at the moment that the vehicles and the pedestrians collide and then drivers are thrown out of the vehicles, and the safety net is quickly unfolded between a vehicle wheel fender and an pillar A, so that protection is achieved between the ground and the heads of the pedestrians. The heads of the pedestrians are in contact with the safety net first, and then the pedestrians fall into the ground after a large amount of collision energy is buffered. Accordingly, the acute injury degree due to the hitting to the heads of the pedestrians is effectively lowered.
Owner:ZHEJIANG GEELY HLDG GRP CO LTD +1

Novel non-psychotropic cannabinoids

Novel non-psychotropic cannabinoids are disclosed and pharmaceutical compositions comprising these novel compounds are described for preventing neurotoxicity, neuroinflammation, immune or inflammatory disorders comprising as active ingredient the stereospecific (+) enantiomer, having (3S,4S) configuration of Δ6 tetrahydrocannabinol type compounds. The compositions are particularly effective in alleviating and even preventing neurotoxicity due to acute injuries to the central nervous system, including mechanical trauma, compromised or reduced blood supply as may occur in cardiac arrest or stroke, or poisonings. They are also effective in the treatment of certain inflammatory disorders and chronic degenerative diseases characterized by neuronal loss and chronic pain including neuropathic pain.
Owner:PHARMOS

Low-damage implanted nerve electrode

InactiveCN104857630AReduce fretting damageReduce implant damageInternal electrodesExternal electrodesEngineeringIn vivo
The invention relates to a low-damage implanted nerve electrode. The low-damage implanted nerve electrode comprises a base portion, a connecting portion and a handle portion; flexible hinges are connected between the base portion and the connecting portion; and one end of the handle portion is connected with the connecting portion. According to the low-damage implanted nerve electrode of the invention, the base is designed based on a flexible mechanism design ideal, and therefore, coupling degree between the electrode and an brain tissue interface can be enhanced, and fretting damage caused by long-term contact between the electrode and a nerve tissue can be decreased in a multi-degree-of-freedom manner; the front end of the handle is designed to a semicircle corner, so that fretting damage can be further reduced; and the exterior of the electrode is provided with an outwards-protruding streamline degradable coating, so that electrode implantation damage can be reduced. The implantation shape of the electrode and the fretting working state shape of the electrode do not interfere each other; acute injuries are smaller when the electrode is implanted; when the electrode works for a long time, fretting damage can be decreased in a plurality of directions; damage to nerve cells can be decreased through the integration of many aspects; the reliability of the micro electrode can be improved; and the nerve electrode can be left in vivo for a long term stably.
Owner:SHANGHAI JIAO TONG UNIV
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