76 results about "Muscle regeneration" patented technology

Therapeutic compositions of microspheres for application to wounds and/or lesions for accelerating wound healing and muscle regeneration. The microspheres are made up of non-biodegradable material having a substantial surface charge. The therapeutic composition further includes a pharmaceutically acceptable carrier in which the microspheres are insoluble and a container for holding the composition. The therapeutic composition further contains pharmacologic agents or biologics that accelerate the wound healing process.

The present inventors studied the effects of inhibiting the IL-6 signaling pathway on muscle cell growth. As a result, they discovered that, administering an IL-6 inhibitor can promote the adhesion, proliferation, and differentiation of satellite cells and therefore muscle regeneration.

The present invention relates to a method of treating and/or ameliorating one or more symptoms of sarcopenia and age-related muscle degeneration in a mammal.

An improved device and method for extended repair and regeneration of muscle tissue. An exemplary device comprises (a) a scaffold comprising an ECM component; (b) a combination of growth factors such as VEGF and IGF; and (c) a population of myogenic cells. Implantation of the device leads to muscle regeneration and repair over an extended period of time.

The present invention relates to the field of nutritional support for individuals and reducing the effects of muscle conditions caused by high levels of physical activity. In particular, the invention provides dietary formulations, compositions comprising these formulations and uses of these compositions to support the body's muscle regeneration process.

The invention provides a clinical nutrient formulation special for sarcopenia, comprising, by weight, 18-30 parts of proteins, 9-13 parts of fat, 40-52 parts of carbohydrates, 4-8 parts of dietary fibers, 0.6-1.2 parts of macro elements, 0.01-0.03 part of trace elements, 0.005-0.02 part of fat-soluble vitamins, 0.005-0.20 part of water-soluble vitamins, 0.2-1 part of dietary essences, 0.07-4 partsof medicinal and edible ingredients, 0.1-1 part of natural plant compounds, and 0.03-0.6 part of new resource foods. The invention also provides a preparation method of the clinical nutrient formulation special for sarcopenia. The clinical nutrient formulation special for sarcopenia herein can meet the demand of a patient with sarcopenia for comprehensive balanced nutrition, can also improve bodyquality of the patient with sarcopenia and promote myodynamia recovery and muscle regeneration.

The present invention describes an antigen-binding construct comprising a first agent which binds to a stem cell specific marker molecule and a second agent which binds to a tissue specific marker molecule. In particular, the invention describes a construct wherein the tissue specific marker is a muscle specific marker molecule. Such a construct may be used in a pharmaceutical composition for use in muscle regeneration or heart disease.

The invention provides a drug for promoting myoblast proliferation and improving myoblast autophagy level, which is characterized in that the active ingredient of the drug is DNA tetrahedron. The invention also provides a new drug for promoting muscle regeneration, which is prepared by taking a DNA tetrahedron as an active ingredient and adding pharmaceutically acceptable auxiliary materials. Theinvention provides the new application of the DNA tetrahedron in preparation of muscle regeneration promoting drugs, and the DNA tetrahedron has a very good application prospect.

The invention discloses a Chinese herbal preparation for treating uterine bleeding after drug abortion, which is made from following raw materials in weight proportion: 2 to 6 parts of astragalus root, 1.5 to 4 parts of agrimony, 0.9 to 2 parts of Chinese angelica, 2 to 4 parts of leonurine, 0.3 to 0.9 part of powdered notoginseng root, 1.5 to 3 parts of portulaca, 1 to 3 parts of redroot gromwell root, 0.8 to 2 parts of aspidium, 0.6 to 2 parts of bitter orange and 0.6 to 2 parts of dried rehmannia root. The invention integrates the functions of Qi supporting and blood enriching, muscle regeneration and hemostasis and heat clearing and blood cooling and cures uterine bleeding after drug abortion with safety, reliability and without pain and can obviously increase complete abortion rate and reduce bleeding quantity of the uterine to shorten bleeding time and avoid twice curettage.

The invention discloses a skeletal muscle whole organ acellular matrix, its derived medical products, such as particles, fluidized compositions, gels and active peptides, and preparation and use methods of the matrix and the medical products. The skeletal muscle whole organ acellular matrix completely reserves the skeletal muscle three-dimensional parallelly-arrayed skeletal muscle basement membrane ultra-structure, the vascular matrix network and muscle-tendon joints, reserves large amounts of bioactive components comprising growth factors, hyaluronic acid, glycosaminoglycan, laminins and the like, is highly affinity to muscle-derived stem cells, has the advantages of certain mechanical strength and toughness, thorough decellularization, no obvious immunological rejection, and no ethical or moral issues, and is a skeletal muscle regeneration scaffold and platform having the most advantages reported so far. The prepared skeletal muscle whole organ acellular matrix and its derived medical products can be used for the in-vitro and in-vivo construction and regeneration of the skeletal muscles, are suitable for restoring the skeletal muscle coloboma of various positions in various ranges, and are expected to solve the large-range skeletal muscle coloboma restoration and muscle regeneration problems.

The invention relates to a muscle regeneration agent, which belongs to the field of the plastic surgery. The muscle regeneration agent is an injection-type muscle regeneration agent which is prepared by the following steps: under the protection of the cell wall-degraded fusion agent, newt cells with regeneration ability in the animal kingdom are fused with the wall-degraded cells of tested mice to realize the growth of bulgy histiocytes, the histiocytes growing after the fusion of degraded cell walls of newt cells are further accepted, and are prepared into the injection-type muscle regeneration agent with the cell wall-degraded fusion agent and the injection solvent after in vitro expansion. The muscle regeneration agent can be used for nose augmentation, chin augmentation and breast augmentation by the injection method (in one or more steps) in the plastic surgery. Muscle tissues can grow and bulge at the injection positions to the designed effect after injection. The injection method can also be applied to eliminating wrinkles and avoiding wrinkles from appearing in a long term.

The invention provides a porcupine oil agent for treating burns and scalds and skin erosion. The agent contains porcupine oil, wherein the porcupine oil is oil extracted from porcupine tissue. The porcupine oil agent also contains the following components in parts by weight: 100-300 parts of porcupine oil, 6-8 parts of rheum officinale, 3-5 parts of borneol, 8-12 parts of clove, 6-8 parts of bulbus fritillariae cirrhosae, 5-8 parts of sanguisorba officinalis, 5-8 parts of plantain herb and 5-8 parts of radix scutellariae. The preparation method comprises the steps of crushing the rheum officinale, the borneol, the clove, the bulbus fritillariae cirrhosae, the sanguisorba officinalis, the plantain herb and the radix scutellariae separately, and then mixing with the porcupine oil evenly. The porcupine oil agent has the functions of clearing heat, diminishing inflammation, promoting blood circulation to remove blood stasis, eliminating stagnation, activating collaterals, alleviating pain, removing swelling, promoting muscle regeneration and removing a scar, and is used for treating burns and scalds, and the effective rate reaches 95.93%.

The invention relates to a muscle regeneration promoting medicine for treating burns and scalds. The muscle regeneration promoting medicine comprises the following components: 5-15 parts of carbonized hair, 8-15 parts of cottonrose hibiscus, 3-10 parts of hairyvein agrimony, 5-10 parts of cockroach, 6-10 parts of red peony root, 15-20 parts of Impatiens textori Miq, 5-15 parts of elephant hide, 15-20 parts of borneol and 10-20 parts of pearl powder. The muscle regeneration promoting medicine for treating the burns and the scalds is purely herbal external liniment or spray, and has the characteristics of low cost, quick effect, good therapeutic effect and no toxic side effects.