6 results about "Muscle regeneration" patented technology

Provided is a composition for preventing, improving, or treating muscular disorders including sulfonamide-based compounds or salts thereof. According to the present disclosure, the sulfonamide-based compounds or salts thereof may prevent inhibition of differentiation of myoblasts by regulating the expression of PHF20 and YY1. Accordingly, since the composition may prevent or alleviate muscle loss, promote muscle regeneration, and improve muscle exercise function, balance ability, and grip strength recovery ability through increased muscles and changes in ratio of muscle fibers, the composition may be effectively used for therapeutic agents, foods, or feeds for preventing, improving or treating muscle disorders, and improving muscle functions or muscle mass.

The present invention relates to the use of a hemp seed extract for preventing or ameliorating muscle diseases by promoting myoblast differentiation or muscle regeneration. In the present invention, the hemp seed extract may exhibit preventive or therapeutic effects on various muscle diseases by increasing muscle mass, strengthening muscle power, improving muscle function, and enhancing exercise performance, and also has an effect of improving muscle function in healthy individuals in addition to treating muscle diseases.

The present application relates to the technical field of external use of traditional Chinese medicine, in particular to an external use synthetic traditional Chinese medicine composition for treating osteomyelitis, sinus tract and stubborn ulcer and a preparation method thereof, which comprises, by weight, 10-15 parts of honeysuckle, 10-15 parts of dandelion, 10-12 parts of purple flower ground ivy, 6-10 parts of Chinese cork tree, 6-10 parts of bitter apricot seed, 5-8 parts of red root of sophora, 5-8 parts of Chinese angelica, and 1-4 parts of borneol; the present application is applicable to the infection period and the repair period, realizes the integration of anti-inflammatory, bacteriostasis, muscle regeneration and repair, adopts low-temperature ultrasonic extraction, avoids high-temperature damage to heat-sensitive components, has stronger and more stable efficacy, the formula contains blood-activating and stasis-removing components such as red root of sophora, Chinese angelica, frankincense and myrrh, can promote the penetration of the medicine into deep tissues, has a remarkable effect on the sinus tract and osteomyelitis wound, is a pure traditional Chinese medicine for external use, does not add hormones and antibiotics, is mild in nature, and is suitable for long-term use.

The present invention relates to the use of mesenchymal stem cells to reduce inflammation and immune responses for neuromuscular injuries and limb transplants. A particular preferred embodiment relates to use of mesenchymal stem cells that are modified to express interleukin-10 in limb transplantation surgery. In particular embodiments, the present invention also provides a method of improving nerve and muscle regeneration and functional outcome for limb transplantation in a mammalian limb transplant recipient by administering to the limb transplant recipient a therapeutic amount of mesenchymal stem cells.

Provided herein are compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy. In some embodiments, the compositions comprise a prostaglandin E2 (PGE2) compound and a myotoxin. In some embodiments, the muscle damage, injury, or atrophy is the result of a nerve injury, a surgical procedure, or a traumatic injury. Methods of promoting muscle regeneration and methods of increasing muscle mass are also provided herein.

The application belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating hand-foot syndrome caused by antitumor drugs. The application takes 'clearing heat and resolving toxins, cooling blood and activating blood, and astringing and promoting muscle regeneration' as the core principle, constructs a whole-cycle management system from early prevention and intervention to late ulcer repair, and provides a traditional Chinese medicine treatment scheme with pertinence and practicability for patients with hand-foot syndrome caused by antitumor drugs. The traditional Chinese medicine composition is composed of Qingdai, Phellodendri Cortex, Scutellariae Radix, Sanguisorba officinalis, Arnebia euchroma, Boswellia sacra, Commiphora myrrha and Glycyrrhiza uralensis. The traditional Chinese medicine composition has the advantages of reducing the classification of hand-foot syndrome, effectively relieving the pain symptoms of patients, and steadily improving the quality of life of patients.