149 results about "Burn injury" patented technology

A non-invasive method of characterizing burn injuries using near infrared spectroscopy is described. In the method, a beam of light is emitted into the burnt tissue portion at two or more different tissue depths. The spectra are then compared using multivariate analysis to determine diagnostic regions of the spectra. This information is used to categorize the burn. In some cases, the diagnostic regions correspond to wavelengths related to the hemodynamics of the tissue portion. The spectra can also be repeated over time, thereby allowing trends and changes in the spectra to be measured. This data is in turn used to categorize the burn as either a superficial burn, partial thickness burn, deep partial burn or a full thickness burn. Once the burn has been categorized, the clinician can intervene as needed to treat the burn.

The present specification discloses an endoscope having a tip section equipped with multiple viewing elements. Each of the viewing elements' field of view is illuminated by a discrete illuminator, such as a LED, being operated in a flash mode. The flash mode of operation of the LEDs enable doctors to obtain a position of the endoscope tip within a patient's body from outside by viewing the light emitted by the LEDs. Since the light is emitted for short pre-defined periods of time, the heat generated by the LEDs during their periods of operation is within a safe threshold value, and does not cause any burn injury inside the patient's body.

The invention provides a synthetic polypeptide of Formula I′:

The invention discloses a preparation method of a self-adhesive hydrogel having anti-freezing/heat-resistant performance. The method adopts a hydrogel solvent system consisting of glycerin and a watermixed system, and powerful hydrogen-bond interaction between glycerin and water enables water to be stably immobilized in a polymer network, can destroy the formation of ice crystal lattices at a lowtemperature and prevent moisture volatilization at a high temperature, and endows the hydrogel with long-term stability, anti-freezing performance and heat resistance. Besides, synergy between polydopamine, glycerin and polymer network enhances the mechanical property of hydrogel, so that the hydrogel has high strength, high toughness and good restorability. Furthermore, the addition of the polydopamine component makes hydrogel have good adhesion, and hydrogel can be adhered to surfaces of substrates with different chemical properties. The self-adhesive hydrogel with the anti-freezing/heat-resistant performance prepared with the method can be used as a wearable dressing to protect skin from cold injury or burn injury in an extremely cold or hot environment.

The invention discloses a resin CBN (cubic boron nitride) grinding wheel for machining a saw blade base body. The resin CBN grinding wheel comprises a base body and an abrasive material layer. The abrasive material layer comprises the following raw materials in percent by volume: 15%-30% of CBN abrasive materials, 30%-45% of phenolic resin powder, 3%-6% of villiaumite grinding-aiding materials, 5%-15% of heat conduction materials, 5%-25% of metallic oxide, 2%-5% of solid lubricating materials and 4%-8% of pore forming materials. Compared with a common white corundum grinding wheel, the resin CBN grinding wheel is high in grinding amount, high in machining efficiency, long in finishing interval and low in speed of loss; and the grinding wheel changing frequency is reduced. Because the grinding wheel has high self-sharpening performance, burn injury and slow grinding of the CBN grinding wheel can be eliminated in a grinding process. On a grinding machine with low revolving speed of 1450 revolutions per minute, the CBN grinding wheel is used for replacing the common white corundum grinding wheel, and the saw blade base body can be quickly ground into a saw blade base body with the given size.

A system for prevention of fires in operating rooms as frequently arises from electrocautery and laser systems comprising an electrocautery instrument having a shielding gas that is expelled from the distal-most end thereof to thus prevent the cautery tip spark from coming into contact with an oxygen-enriched environment that may otherwise propagate the spark into a full-fledged fire. The systems can further be coupled with oxygen sensors, alarms and mechanisms for limiting the delivery of oxygen. Additional refinements include incorporating heat sensory strips to the distal ends of oxygen delivery systems, which are in turn coupled with a thermocouple device set to turn off oxygen delivery or electrosurgical system at given levels of heat to thereby limit the extent of burn injury. Further refinements also include the use of nonflammable inserts to the tips of the oxygen delivery systems such that in the event of a fire the plastic does not catch on fire and in effect turn into a blowtorch.

The present invention describes the incorporation of liposomal gene constructs directly into a wound to further improve wound repair, or into wound coverage and/or closure materials to enhance the functionality of the material. The present invention further describes the use of human fetal membranes (e.g., amnion) enhanced with the liposomal gene therapy as a wound coverage material in full-thickness wound repair. The enhanced fetal membranes or enhanced cadaver skin have advantages over currently used materials lacking the liposomal gene construct and are an efficient and safe approach to improve clinical outcome in patients with burn injuries.

Cellfree adipose tissue extracts, implants including the same and methods for the preparation thereof. The extracts and implants are capable of inducing adipogenesis and angiogenesis and are, thus, useful in applications including soft tissue repair and engineering and angiogenesis induction, e.g., in wound healing, treatment of burn injuries and ischemic conditions.

The present invention provides methods, software, and systems for assessing a burn injury.

A method is disclosed to treat a patient having a wound area, such as a burn injury. The method provides a plurality of epidermal/dermal cells, and applies that plurality of epidermal/dermal cells to the wound area.

Provided are a water-absorbent antibacterial dressing for burn injuries and wounds and a preparation method and application thereof. The dressing is a stereoscopic reticular porous sponge, chitosan isadopted as a framework, a super absorbent polymer combined with an antibacterial agent control-released carrier is adopted as branched chains, and macromolecules or polymers of flexiblestructures areadopted as a cross-linking agent among the branched chains. The antibacterial agent control-released carrier is loaded with an antibacterial agent. The weight ratio of the chitosan to the super absorbent polymer to the antibacterial agent control-released carrier to the cross-linking agent to the antibacterial agent in the antibacterial dressing is (0.6-2):(40-60):(0.6-25):(0.1-10):(1-10). The dressing has water absorption performance, moisture retention performance, air permeability, a barrier property, a long-acting antibacterial property, a bleeding stopping function and high strength andis easy to tear off, and is a novel antibacterial compound dressing with a broad-spectrum antibacterial effect. The dressing can be prepared through a one-pot method, is simple in preparation process,low in cost, prominent in treatment effect and high in safety and has remarkable medical value and industrialization potential.

[Summary]

[Object]

To develop a preparation and a treatment method effective for improving a state of a bald hear, promoting hair growth, and restoring injuredskin tissues, supporting tissues, and cardiac muscle.

[Solution]

A preparation containing atrial diuretic hormone family molecules are used for restoration and regeneration of a tissue and an organ. The preparation is used for growing hairs and/or for improving and restoring failures of skin, mucosa, and subcutaneous tissue such as bed bore, rough and dry skin, burn injuries, necrosis, and psoriasis, and also for improving cardiac muscle failures.

The invention provides a cyclic polypeptide of Formula I (SEQ ID NO: 1):

X1-R-X3-X4-L-S-X7-X8-X9-X10-X11-X12-X13  I

or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein X1, X3, X4, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor. The invention also relates to a method for manufacturing the polypeptides of the invention or bioconjugates thereof, and their therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

The invention belongs to the field of biomedical material application, and particularly relates to a preparation method of a bacteriostatic and wound restoration promoting chitosan hydrogel dressing. According to the preparation method, firstly, chitosan is prepared into microspheres in a dispersion medium by a Pickering emulsion process; after glutaraldehyde fixation, the microspheres are uniformly dispersed into a chitosan water solution; then, glutaraldehyde crosslinking agents are used for preparing hydrogel; and through soaking and flushing by deionized water, excessive cross linking agents and certain moisture are removed to obtain the chitosan hydrogel dressing. The dressing has soft textures; the inside has the uniform three-dimensional hole structures; wound percolate and secreta can be sucked away; the chitosan microspheres loaded by the hydrogel have high-density positive charges; the bacteria growth can be inhibited; the additional addition of bacteriostatic medicine is not needed; the wound restoration can also be promoted; and the dressing can be applied to the restoration of wound and the protection of various kinds of skin wound surfaces such as burn injury, mechanical trauma, diabetic foot and pressure sores.

The invention discloses an isolation implement for treatment of limb surface burn injuries. The isolation implement comprises a fixing mechanism, a protecting mechanism and a nursing mechanism. The fixing mechanism comprises a first fixing ring and a second fixing ring; the protecting mechanism comprises an air bag protecting sleeve in an annular structure, and the first fixing ring and the secondfixing ring are connected with two ends of the air bag protecting sleeve respectively; the nursing mechanism comprises a sterilization spraying pipe which is closely attached to an inner cavity of the air bag protecting sleeve through hook-and-loop fasteners, and one end of the sterilization spraying pipe penetrates the first fixing ring while the other end of the sterilization spraying pipe is capped. By inflation for forming the protecting sleeve, supporting and protecting can be realized, and secondary injuries caused by impact can be prevented. In addition, the isolation implement is convenient to mount, light in weight, portable and convenient to collect due to small size after deflation, and by the sterilization spraying pipe for spraying sterilization mist, breeding of germs is reduced, and infection can be prevented.

The invention provides a device for spirally grinding a back knife face of a spiral drill based on electrospark wire cutting, which comprises a spiral drill, a rotary shaft, a ball screw nut pair, a rolling guide pair and a rack; the spiral drill is mounted at one end of the rotary shaft by a spanner three-jaw drill chuck; the other end of the rotary shaft is connected with a first step motor through a shaft coupler; the rotary shaft is mounted in a bearing seat by a bearing; a connecting plate is fixed to the bottom of the bearing seat; the ball screw nut pair is composed of a screw rod and a nut sleeved to the screw rod; the screw rod is connected to a second step motor; the nut is fixedly connected with the connecting plate; the rolling guide pair is composed of a groove arranged on a rolling guide block and a guide embedded in the groove; the rolling guide block is fixed to the bottom of the connecting plate; and the guide is fixed to the rack. The device provided by the invention has the advantages that: the device may not cause grinding burn injury of the back knife face for no grinding force, is not influenced by knife materials and knife sizes and can grind spiral drills of various conductive knife materials and sizes.

The invention discloses a 3D printer with a finished product fast taking-out function. The 3D printer comprises a 3D printer body. A pair of strip-shaped grooves is formed in the lower wall face of a printing platform of the 3D printer body. Strip-shaped sliding rails are embedded in the strip-shaped grooves. A pair of moving wheels is assembled on the strip-shaped sliding rails. Support seats are installed on the upper wall faces of the moving wheels. Bearing plates are installed on the upper wall faces of the two pairs of support seats. First strip-shaped support seats are fixed to the upper wall faces of the bearing plates. The side wall faces of the first strip-shaped support seats are provided with first grooves. First swing motors are installed in the first grooves. First support rods are installed at the driving ends of the first swing motors in a sleeved mode. Arc-shaped art knives are installed on the first support rods in a sleeving mode. The 3D printer is novel in structure and convenient to operate, and effectively helps people to take out a formed article printed by the 3D printer, taking of the finished product saves time and labor, loss of the finished product due to inconvenient taking is reduced, and meanwhile, the phenomenon of burning injury of people is reduced.

The invention discloses a welding frame for a lead-acid storage battery. The welding frame comprises a working table and a mould box arranged on the working table, wherein the mould box comprises a positioning frame, a bracket, a pressing device and at least one positioning box; the positioning frame is provided with a connection shaft, is rotationally arranged on the bracket through the connection shaft, and is used for clamping the positioning box; the positioning box comprises a fixed plate and a movable plate; the positioning frame is provided with a guide groove; and the pressing device can drive a pressure plate to move along the guide groove for pressing a pole piece and a spacing plate which are clamped between the fixed plate and the movable plate. As the positioning box comprises the movable plate capable of moving, a pole lug is first arranged downward, the spacing plate is not beyond the connection place of the pole piece and the pole lug, the pressing mechanism can press or release the pole piece and the spacing plate which are clamped in the positioning box, the positioning frame rotates to drive the rotation of the positioning box to allow the pole lug is to be upward for welding, so that the burn injury or the scald injury of the spacing plate can be prevented, the positive-negative cross infection of pole sets can be avoided, the production efficiency is improved, and the production intensity is reduced.