Preparation method of self-adhesive hydrogel having anti-freezing/heat-resistant performance

A hydrogel and self-adhesion technology, which is applied in the field of preparation of self-adhesive hydrogels and achieves the effects of high toughness recoverability, good recoverability and good self-adhesion.

Inactive Publication Date: 2018-01-30
SOUTHWEST JIAOTONG UNIV
View PDF4 Cites 35 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, it is still a challenge to design self-adhesive hydrogels with long-term stability, frost and heat resistance

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Weigh 0.5 mg / ml dopamine and react under the condition of PH=8 for 20 minutes to obtain polydopamine dispersion. Weigh 2.0g acrylamide, 0.4g acrylic acid, 1% (wt.%) ammonium persulfate and 1% (wt.%) N,N-methylenebisacrylamide crosslinking agent and add them to the polydopamine dispersion, Stir well to make it evenly mixed, then add 20% (vol.%) glycerin into the mixed solution, then add 5ul tetramethylethylenediamine, stir well, and finally form a hydrogel by free radical polymerization.

Embodiment 2

[0015] 1.5 mg / ml dopamine was weighed and reacted under the condition of PH=10 for 20 minutes to obtain a polydopamine dispersion. Weigh 2.0g acrylamide, 0.4g acrylic acid, 5% (wt.%) ammonium persulfate and 5% (wt.%) N,N-methylenebisacrylamide crosslinking agent and join in the polydopamine dispersion liquid, Stir well to make it evenly mixed, then add 50% (vol.%) glycerin into the mixed solution, then add 20ul tetramethylethylenediamine, stir well, and finally form a hydrogel by free radical polymerization.

Embodiment 3

[0017] Weigh 3.5 mg / ml dopamine and react under the condition of PH=11 for 20 minutes to obtain polydopamine dispersion. Weigh 2.0g acrylamide, 0.4g acrylic acid, 15% (wt.%) ammonium persulfate and 10% (wt.%) N,N-methylenebisacrylamide cross-linking agent and join in the polydopamine dispersion liquid, Stir well to make it evenly mixed, then add 90% (vol.%) glycerin into the mixed solution, then add 30ul tetramethylethylenediamine, stir well, and finally form a hydrogel by free radical polymerization.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a preparation method of a self-adhesive hydrogel having anti-freezing/heat-resistant performance. The method adopts a hydrogel solvent system consisting of glycerin and a watermixed system, and powerful hydrogen-bond interaction between glycerin and water enables water to be stably immobilized in a polymer network, can destroy the formation of ice crystal lattices at a lowtemperature and prevent moisture volatilization at a high temperature, and endows the hydrogel with long-term stability, anti-freezing performance and heat resistance. Besides, synergy between polydopamine, glycerin and polymer network enhances the mechanical property of hydrogel, so that the hydrogel has high strength, high toughness and good restorability. Furthermore, the addition of the polydopamine component makes hydrogel have good adhesion, and hydrogel can be adhered to surfaces of substrates with different chemical properties. The self-adhesive hydrogel with the anti-freezing/heat-resistant performance prepared with the method can be used as a wearable dressing to protect skin from cold injury or burn injury in an extremely cold or hot environment.

Description

technical field [0001] The invention relates to the technical field of hydrogel application and preparation, in particular to a method for preparing a self-adhesive hydrogel with antifreeze / heat resistance properties. Background technique [0002] Self-adhesive hydrogels can be used in fields such as skin repair, wound suturing and wearable devices due to their high water content and soft structure similar to natural tissues. However, most of the existing adhesive hydrogels have poor mechanical properties. , It is easy to be damaged during use, which will cause the wound to be exposed to the air and cause wound infection. Therefore, it is very important to design a hydrogel with high strength and self-adhesive properties. [0003] However, when a hydrogel with high strength and self-adhesion is placed in an extreme environment of overheating or overcooling, water molecules cannot be stably fixed in the polymer network, and thus are easily lost during use. High temperatures...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C08F283/00C08F220/56C08F220/06C08F222/38C08G73/06C08K7/24C08K3/22C08K3/32
Inventor 鲁雄刘柯志韩璐闫力维甘东林贾占荣
Owner SOUTHWEST JIAOTONG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap