Preparation method of self-adhesive hydrogel having anti-freezing/heat-resistant performance

Abstract

The invention discloses a preparation method of a self-adhesive hydrogel having anti-freezing / heat-resistant performance. The method adopts a hydrogel solvent system consisting of glycerin and a watermixed system, and powerful hydrogen-bond interaction between glycerin and water enables water to be stably immobilized in a polymer network, can destroy the formation of ice crystal lattices at a lowtemperature and prevent moisture volatilization at a high temperature, and endows the hydrogel with long-term stability, anti-freezing performance and heat resistance. Besides, synergy between polydopamine, glycerin and polymer network enhances the mechanical property of hydrogel, so that the hydrogel has high strength, high toughness and good restorability. Furthermore, the addition of the polydopamine component makes hydrogel have good adhesion, and hydrogel can be adhered to surfaces of substrates with different chemical properties. The self-adhesive hydrogel with the anti-freezing / heat-resistant performance prepared with the method can be used as a wearable dressing to protect skin from cold injury or burn injury in an extremely cold or hot environment.

Description

technical field [0001] The invention relates to the technical field of hydrogel application and preparation, in particular to a method for preparing a self-adhesive hydrogel with antifreeze / heat resistance properties. Background technique [0002] Self-adhesive hydrogels can be used in fields such as skin repair, wound suturing and wearable devices due to their high water content and soft structure similar to natural tissues. However, most of the existing adhesive hydrogels have poor mechanical properties. , It is easy to be damaged during use, which will cause the wound to be exposed to the air and cause wound infection. Therefore, it is very important to design a hydrogel with high strength and self-adhesive properties. [0003] However, when a hydrogel with high strength and self-adhesion is placed in an extreme environment of overheating or overcooling, water molecules cannot be stably fixed in the polymer network, and thus are easily lost during use. High temperatures...

AI Technical Summary

Problems solved by technology

Therefore, it is still a challenge to design self-adhesive hydrogels with long-term stability, frost and heat resistance, and high mechanical properties to maintain good high mechanical properties and self-adhesion at different temperatures.