220 results about "Extracorporeal circulation" patented technology

The invention provides an ultrasonic blood flow sensor based on temperature compensation, and relates to the field of medical instruments. The ultrasonic blood flow sensor based on temperature compensation comprises an ultrasonic probe assembly, a temperature sensor and a detection circuit, and the ultrasonic probe assembly is used for emitting ultrasonic waves to an extracorporeal circulation pipeline and receiving the ultrasonic waves penetrating through the extracorporeal circulation pipeline. According to the ultrasonic blood flow sensor based on temperature compensation, the problem that the measurement precision is reduced due to blood temperature changes can be effectively solved, and the ultrasonic blood flow sensor based on temperature compensation can be applied to application scenes such as extracorporeal circulation operations, such as the ECMOs process. Accurate blood flow monitoring is crucial to adjustment of ECMO system parameters, optimization of membrane lung oxygenation effect and guarantee of patient treatment effect. The sensor can provide high-precision and reliable blood flow data and help a doctor to more accurately evaluate the extracorporeal circulation state of a patient, so that a more accurate medical decision is made, and the treatment success rate is increased.

The embodiment of the invention provides a continuous blood oxygen monitoring system in extracorporeal circulation and a control method thereof. The continuous blood oxygen monitoring system comprises a vein sensor, an artery sensor, a blood flow sensor, an oxygen sensor, a carbon dioxide sensor, a controller and a display, the vein sensor monitors the vein blood oxygen saturation degree; the artery sensor monitors arterial oxygen saturation and hematocrit; the blood flow sensor monitors the blood flow of the artery pipeline; the oxygen sensor monitors the oxygen concentration of the oxygenator; the carbon dioxide sensor monitors the carbon dioxide concentration of the oxygenator; the display provides an interaction control, responds to a trigger operation acting on the interaction control, sends an interaction instruction to the controller, and updates information displayed in an interaction interface according to the control of the controller; the controller receives the interaction instruction and executes processing corresponding to the interaction instruction; the processing includes controlling display information of the display; the display information comprises information corresponding to the monitoring parameters. The scheme ensures the safety and effectiveness of the treatment process.

The invention discloses a postoperative sub-delirium syndrome risk prediction system for a cardiac surgery patient, and relates to the technical field of medical treatment, and the system comprises a clinical data collection module which is used for collecting multi-dimensional clinical data of the cardiac surgery patient in a perioperative period under extracorporeal circulation, the data comprises patient baseline information, preoperative neurocognitive function evaluation indexes, intraoperative physiological parameters and postoperative early-stage vital signs; and the risk identification module is used for utilizing a single-factor statistical analysis mechanism. According to the postoperative sub-delirium syndrome risk prediction system for the cardiac surgery patient, accurate prediction of the sub-delirium syndrome risk is achieved by collecting multi-dimensional clinical data of the patient in the perioperative period, such as baseline information, preoperative neurocognitive function, intraoperative physiological parameters and postoperative early-stage vital signs; the independent risk factors are scientifically screened and quantified by using single factor analysis and a multivariate Logistic regression model, and the problem of incomplete data dimensions in traditional evaluation is effectively solved.

A blood pump-oxygenator system (250A, 250B, 250C) for increasing perfusion and oxygen levels in the body of a patient (P), comprising: a blood inlet (80) and a blood outlet (90) connected to form a circuit operable as a cardiopulmonary bypass system suitable for extracorporeal treatment of the blood of the patient; a first blood pump (11) and a first oxygenator (20), wherein the first blood pump (11) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the first oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The system further comprises a second blood pump (13) and a second oxygenator (21), wherein the second blood pump (13) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the second oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The circuit comprises a first branch (101) and a second branch (102) arranged in parallel with each other, the first branch (101) accommodating the first blood pump (11) and the first oxygenator (20), and the second branch (102) accommodating the second blood pump (13) and the second oxygenator (21). The system further comprises a pump control unit (290) wherein the first and second blood pumps (11, 13) are configured to be controlled by the pump control unit (290) to increase or decrease the blood flow through the corresponding oxygenator (20, 21) by changing the proportion of the blood flow through the first and second oxygenator (20, 21).

The invention relates to a control method and device of an extracorporeal circulation system, computer equipment and a storage medium. The method comprises the steps that current perfusion parameters and target perfusion parameters are obtained, parameters of a state space model are updated according to the current perfusion parameters, the target perfusion parameters and the state space model, an updated state space model is obtained, and then the current perfusion parameters are adjusted according to the current perfusion parameters and the updated state space model; therefore, during regulation and control, the target perfusion parameter is considered, the state space model is updated according to the target perfusion parameter and the current perfusion parameter, then the current perfusion parameter is used as the initial value of the updated state space model, and the current perfusion parameter is regulated, so that automatic regulation is realized, the manual regulation time of an operator is shortened, and the manual regulation efficiency is improved. And the adjusting efficiency is improved. Meanwhile, the risk of postoperative organ injury of the patient is reduced and the recovery speed of the patient is accelerated through reasonable tissue perfusion, and the treatment overhead of the patient is reduced to a certain extent.

Disclosed in the present application are an HCT prediction method and system, a device, and a medium. Photons in a photon group are emitted into an extracorporeal circulation blood model so that the photons are reflected, scattered, or absorbed during movement. The extracorporeal circulation blood model is a model constructed on the basis of the thickness of an extracorporeal circulation tube, the thickness of the blood, and the distance from a light source generator to a detector. Light intensity data corresponding to photons reaching the detector are acquired. The acquired light intensity data are input into a prediction model to obtain a hematocrit (HCT) prediction value. The prediction model is a model constructed on the basis of a BP neural network and the relationship between light intensity and HCT. The prediction model combining simulation and neural network increases the data volume, achieves continuous non-invasive estimation of HCT by means of algorithm model optimization, and improves the accuracy of HCT prediction.

The invention relates to an online calibration method for an extracorporeal membrane oxygenation system. A time difference method flow sensor and a Hall sensor collect data, and a host calculates blood pump flow, blood pump rotating speed data and relative indicating value errors and judges whether the data are out of tolerance or not. The on-line calibration device realizes real-time data acquisition and calibration at the stage of treating a patient with the blood pump flow and the blood pump rotating speed, and comprises an on-line calibration device host, a time difference method flow sensor, a Hall sensor and a data line. The Hall sensor is connected with the online calibration device host, one end of the time difference method flow sensor is connected with the online calibration device host, the other end of the time difference method flow sensor is connected with an extracorporeal circulation perfusion pipeline of the extracorporeal membrane oxygenation system, and one end of a pump head of a blood pump of the extracorporeal membrane oxygenation system is connected with a patient through the extracorporeal circulation perfusion pipeline. And the other end is connected with a patient through an extracorporeal circulation drainage pipeline. The accuracy of measured data is improved, and the problem that a conventional optical non-contact rotating speed measuring method cannot be suitable for online calibration of the rotating speed of the blood pump of the in-vitro membrane lung oxygenation system is solved.

The invention relates to the technical field of blood dialysis, in particular to a real-time blood pressure monitoring method of a blood sampling system. According to the method, suspected blood sampling moments and suspected sampling ends are preliminarily screened out through blood pressure deviation conditions according to different change conditions after blood sampling is carried out at the sampling ends, and the blood sampling probability is obtained by analyzing the blood pressure change conditions of the different sampling ends after the suspected blood sampling moments; analyzing the recovery condition after the blood pressure fluctuates according to the suspected blood sampling time, and obtaining a recovery change reduction index according to the reduction change of the recovery condition under continuous sampling; and in combination with accumulation of recovery change reduction indexes and blood sampling probabilities, monitoring and early warning are carried out through comparison analysis of historical patients. The blood sampling condition at the extracorporeal circulation sampling end is analyzed, the fluctuation recovery time reduction condition is compared, the monitoring abnormity is early warned in time, and it is guaranteed that a patient is monitored safely and reliably.

The method for monitoring parameters of a patient during surgery with extracorporeal circulation serves to estimate the presence of AKI risk and comprises calculating a dynamic global index of AKI risk as a logistic regression deriving from a static AKI risk index and a dynamic index of AKI risk. The value and / or the time trend of such global index of AKI risk can be advantageously displayed on a monitor during the surgery. The dynamic AKI risk index is calculated at least on the basis of the extracorporeal circulation time, the minimum level of oxygen supply and the exposure time to oxygen supply below a critical threshold which are measured or determined repeatedly during surgery. Preferably, the dynamic AKI risk index is also calculated on the basis of the minimum mean arterial pressure during surgery and / or the maximum concentration of lactate in the blood during surgery and / or the minimum hematocrit during surgery and / or the fact that the patient has been subjected to transfusion(s) during the extracorporeal circulation.

The invention belongs to the field of medical care informatics, and provides an extracorporeal circulation real-time risk early warning and decision support system based on multi-modal physiological data, which comprises the following steps: collecting multi-modal data in an extracorporeal circulation process; determining the current activation state of each mode, and numbering and identifying the modes in the activation state; respectively executing independent state updating operation on the modes in the activated state; selecting a plurality of reference state units from a historical state set to identify the difference degree between the input feature vector and the plurality of reference state units on the modal structure, and adjusting the participation degree and the influence weight of the reference state units based on the difference degree; and based on the risk evolution trajectory of the reference state unit and the corresponding participation degree and influence weight, determining a risk score value at the current moment, and finally generating a control suggestion.

The utility model discloses an extracorporeal circulation blood vessel connecting structure under a field operation condition, and relates to the technical field of medical instruments. The connecting structure comprises a connecting assembly I and a connecting assembly II; the two ends are respectively inserted into blood vessels on the left and right sides of the broken blood vessel; the first connecting assembly and the second connecting assembly are of the same structure and are symmetrically arranged, and each connecting assembly comprises a puncture assembly, a drainage tube and a connecting base arranged at the end of the drainage tube. The switching structure is connected between the first connecting assembly and the second connecting assembly. According to the extracorporeal circulation blood vessel connecting structure under the field operation condition, rapid and stable connection of broken blood vessels is achieved by designing the connecting structure and the switching structure, and therefore the treatment efficiency and the survival rate of wounded personnel in the field operation environment are remarkably improved.

The invention relates to an extracorporeal circulation control method based on membrane lung resistance and an extracorporeal membrane lung oxygenation system thereof, and aims to solve the core technical bottlenecks of membrane lung blockage, efficiency reduction, embolism risk increase and operation time limitation caused by coagulation activation and thrombosis due to the fact that blood is in contact with non-biological materials in an ECMO system. The core is that pressure sensors at three key positions are used for monitoring an outlet and an inlet of the magnetic suspension blood pump and a membrane lung outlet in real time. And calculating membrane lung resistance pressure difference and scouring resistance pressure difference on the basis. And the system continuously judges whether the pressure difference is abnormal or not. When the pressure difference is normal, the constant flow mode of the blood pump is maintained, and the operation efficiency and stability are guaranteed. And once it is detected that the membrane lung resistance pressure difference and / or the flushing resistance pressure difference are / is abnormal, the blood pump is immediately switched to the pulsation mode. On one hand, thrombus which is deposited or loosened on membrane lung fibers can be physically scoured and scattered, and the blocking process is delayed; on the other hand, the risk that large free thrombus forms embolism can be remarkably reduced.

The utility model discloses a blood extracorporeal circulation device, which belongs to the technical field of blood extracorporeal circulation equipment and comprises an inner tube and an outer tube, the inner tube and the outer tube are integrally nested, one end of the outer tube is connected with an air inlet tube, the air inlet tube is communicated with oxygen inlet equipment, and the other end of the outer tube is connected with an air outlet tube. A temperature changer and a flow speed controller are connected between one end, far away from the air outlet end, of the outer pipe and the oxygen inlet equipment; one end of the inner tube is a liquid inlet end for transporting blood, the other end of a blood inlet of the inner tube is a liquid outlet end, and the liquid outlet end is connected with a temperature sensor, an oxygen saturation sensor, a blood pump and a microembolus filter; the part, in the outer pipe, of the inner pipe is made of a gas exchange membrane material, and the liquid inlet end of the inner pipe is opposite to the gas inlet pipe of the outer pipe. The blood temperature rising process is safer, meanwhile, in the blood temperature rising process, the oxygen saturation index in the blood can be directly adjusted, the blood oxygen value is simple, convenient and controllable on the basis of convenient temperature rising, temperature control and oxygen saturation of in-vitro blood circulation are carried out at the same time, and operation is easy and safe.

The invention provides a method and a device for secondary filtration and re-removal of cholesterol ester after continuous blood purification and blood fat filtration, and belongs to the technical field of medical blood purification. According to the method and the device, the technology of combining enzymolysis, adsorption and membrane separation is adopted for residual CE in a CBP filtering product. The method comprises the following steps: firstly, decomposing CE into small molecules by using specific enzyme, and weakening the combination of CE and other components; residual impurities are further adsorbed through a high-performance adsorption material; and finally, efficient removal of CE is realized by virtue of a high-precision membrane separation technology, so that the residual quantity is reduced to be below a safety threshold value. Compared with a traditional technology, the problems that the CE-containing filtrate is high in recycling risk and low in resource utilization rate are effectively solved, the purity of a filtered product is remarkably improved, technical support is provided for industrial scenes such as plasma exchange, filtrate feedback, biopharmacy and extracorporeal circulation in the medical field, and the application prospect is wide. The safety and the resource utilization efficiency of the blood purification technology are promoted.

An extracorporeal circulation system (10) is provided with: a holder unit (12) integrally having a holder part (18) to which an artificial lung (100) is attached, and a pump drive part (20) for rotating a blood pump (110); and an input part (67) provided separately from the holder unit (12). The holder unit (12) has a pump control part (52) that controls the pump drive part (20) on the basis of information from a sensor for measuring physical property parameters in the circuit and information from the input part (67).

The purpose of the present invention is to provide, inter alia, a management device having a display or another display unit that is easy for a user to visually recognize. A management device (10) manages an extracorporeal circulation device (1) that has an artificial lung device (2), a pump unit (3), and an extracorporeal circulation circuit (IR). The management device (10) has a control unit (111) and a display unit (113) that displays various types of information relating to the extracorporeal circulation device (1). The control unit (111) groups together various types of information (P1) relating to the extracorporeal circulation device (1) into a plurality of groups on the basis of preset relevance information. The display unit (113) has an aggregation display region in which the various types of information belonging to the respective groups are disposed in an aggregated manner.

A device including a display unit that is easily visually recognized by a user, an extracorporeal circulation device including the management device. A management device manages an extracorporeal circulation device including an oxygenation device, a pump unit, and an extracorporeal circulation circuit IR, and includes a display unit that displays various types of information regarding the extracorporeal circulation device, the display unit includes a first display area in which fixed information that is fixed in advance is displayed, and a second display area configured in such a manner that the displayed information is changeable, in which trend graph information of the fixed information displayed in the first display area is displayed in the second display area, and non-fixed information related to the fixed information is displayed.

The present invention relates to the technical field of pipeline sealing detection, and specifically to a blood extracorporeal circulation pipeline sealing detection device, comprising a detection tube, two movable rods are inserted into the top outer wall of the detection tube, clamping mechanisms are provided on both sides of the detection tube, two partitions are welded to the inner wall of the detection tube, each partition is provided with a pressure transmission mechanism, a compressed air strip is welded to the top outer wall of each movable rod, and the inner wall of the detection tube is connected to two reciprocating circular plates by sliding. When the present invention detects the sealing of the blood extracorporeal circulation pipeline, the pipeline can be directly inserted into the corresponding rubber clamping tube platform, and the handle is rotated to stably clamp the pipeline, and the compressed air strip is repeatedly pressed to continuously inflate the pipeline. For the blood extracorporeal circulation pipeline with good sealing performance, the compressed air strip cannot be continuously pressed repeatedly, so the sealing performance of the blood extracorporeal circulation pipeline can be quickly identified.

Bracket assemblies can be used to pole mount medical equipment such as blood parameter monitoring devices, extracorporeal blood pumps, and other medical devices. The use of such pole mount bracket assemblies can serve to minimize congestion of areas around patients receiving medical attention. In some examples, the pole mount bracket assemblies can be made to be easily adjustable and to be readily adaptable to firmly clamp to poles of various diameters.

Provided is an extracorporeal circulation system, which includes an arterial sheath, an inflow tube, a handle, an outflow tube, and a venous sheath that are connected in sequence. The arterial sheath is used for connecting to a carotid artery, and the venous sheath is used for connecting to a vein. The handle includes a housing, as well as a flow controller, a blood filter, and a one-way check valve that are arranged in the housing and are communicated in sequence. The flow controller is connected to the end of the inflow tube away from the arterial sheath, and the one-way check valve is connected to the end of the outflow tube away from the venous sheath. The flow controller includes one body element with a flow-through channel and a flow control element. At least part of the flow control element is received in the body element and is movably connected to the flow-through channel. The flow control element reduces or increases the circulation area of the flow-through channel under an external force. Reverse blood flow from the carotid artery to the femoral vein can be established by using the extracorporeal circulation system of the present invention, thereby preventing a falling thrombus from entering the brain during surgery.

The application discloses a temperature-strain dual-function sensor for extracorporeal circulation system monitoring, and relates to the technical field of flexible electronics and biomedical engineering. The sensor adopts a three-layer stacking structure, and comprises, from top to bottom, a piezoresistive strain response layer based on a silver / graphene / poly(3,4-ethylenedioxythiophene):polystyrene sulfonate composite conductive film, a thermoplastic polyurethane nanofiber heat insulation isolation layer and a temperature sensitive layer based on a graphene / poly(3,4-ethylenedioxythiophene):polystyrene sulfonate composite conductive hydrogel. The temperature-strain dual-function sensor for extracorporeal circulation system monitoring prepared by the application exhibits high sensitivity and fast response characteristics in temperature and strain sensing, and simultaneously exhibits excellent cycle stability and long-term reliability under repeated deformation.

Bracket assemblies can be used to pole mount medical equipment such as blood parameter monitoring devices, extracorporeal blood pumps, and other medical devices. The use of such pole mount bracket assemblies can serve to minimize congestion of areas around patients receiving medical attention. In some examples, the pole mount bracket assemblies can be made to be easily adjustable and to be readily adaptable to firmly clamp to poles of various diameters.

The application discloses an auxiliary instrument for aortic replacement artificial blood vessel surgery, which comprises a collapsible and inflatable bag body which extends into the aorta of a heart to block blood, wherein the bag body is provided with a bag body channel for blood to pass through, and the upper end of the bag body is connected with a drainage tube; the connection end of the drainage tube with the bag body is provided with a drainage tube cavity; the outer side of the drainage tube is provided with a drainage tube through hole for guiding the seepage blood between the bag body and the aorta of the heart into the drainage tube cavity; the drainage tube is respectively provided with a drainage tube channel which is communicated with the bag body channel and is used for sending the blood in the aorta of the heart into an extracorporeal circulation device, an injection channel which is used for injecting or extracting liquid or gas to the bag body so as to make the bag body inflate or shrink, and a seepage blood extraction channel which is used for extracting the seepage blood in the drainage tube cavity; the seepage blood is guided into the drainage tube cavity through the drainage tube through hole, and the seepage blood is extracted through the seepage blood extraction channel, so that the problem of the seepage blood blocking the suture visual field is solved.

To prevent unintended deformation of a pump tube by an adapter component from occurring easily.SOLUTION: An extracorporeal circulation circuit 100 includes a pump tube unit 101. The pump tube unit 101 includes a pump tube 110 and a cassette 120. The cassette 120 has a first holding portion 122A for holding a first held portion 113A and a second holding portion 122B for holding a second held portion 113B. In a use preparation state in which the first held portion 113A and the second held portion 113B are held by the first holding portion 122A and the second holding portion 122B respectively, at least one of the first held portion 113A and the second held portion 113B is rotatable in the periaxial direction of the pump tube 110.SELECTED DRAWING: Figure 1

This invention belongs to the field of extracorporeal circulation monitoring technology and discloses a multi-parameter linkage monitoring system for an artificial heart-lung machine, including an artificial heart-lung machine circuit, a detection component, an execution component, and a controller. The artificial heart-lung machine circuit includes a venous drainage line, a blood reservoir, a blood pump, a membrane oxygenator, an arterial perfusion line, and a gas supply line. The detection component is used to detect venous pressure, fluid level, pressure before and after the membrane oxygenator, arterial perfusion flow rate, blood oxygen, and gas supply pressure and flow rate. The controller performs time alignment on the detection signals within the same sampling period and, combined with changes in similar detection signals in adjacent sampling periods, distinguishes between insufficient drainage, increased membrane oxygenator resistance, and abnormal gas supply, outputting corresponding deceleration, speed limiting, gas supply adjustment, gas supply switching, pump shutdown, alarm, and lockout control signals. This system is used for linkage monitoring and control of abnormal sources in the extracorporeal circulation circuit.

To provide a stable dialysis using a biological monitoring data and the like by appropriately suppressing a decrease in blood pressure during a dialysis treatment.SOLUTION: A dialyzer includes: an extracorporeal circulation blood passage; a dialysis liquid passage; a dialysis membrane provided to partition a part of the extracorporeal circulation blood passage and the dialysis liquid passage; circulation blood amount change rate measurement means for measuring the circulation blood amount change rate ΔBV of the patient; and water removal means for removing a part of the dialysis liquid flowing in the dialysis liquid passage to outside of the system to remove water in the blood from the extracorporeal circulation blood passage to the dialysis liquid passage. The water removal means is controlled such that the water removal speed at the end of the dialysis process is at a constant speed. The water removal means is controlled such that the water removal speed decreases when an inclination of a graph showing a change over time of the circulation blood amount time change rate ΔBV becomes a predefined first value or less in the period other than the end of the process.SELECTED DRAWING: Figure 2

Customizable and intuitive user interfaces are provided for medical systems and devices, such as cardiopulmonary bypass systems, perfusion systems, extracorporeal circulation apparatus, and heart-lung machines, that allow easy access to critical patient data to facilitate blood perfusion, as well as monitoring and adjusting various physiological parameters of the patient and extracorporeal blood flow circuit during procedures such as cardiopulmonary bypass and extracorporeal membrane oxygenation (ECMO).

The invention discloses a method and system for monitoring carbon monoxide in real time during extracorporeal circulation, and relates to the technical field of medical monitoring, and the method comprises the following specific steps: light path construction and gas sampling: presetting distributed monitoring nodes in an extracorporeal circulation pipeline, integrating a corresponding laser light source and a photoelectric detector by each probe, sample gas of each node of a body is synchronously collected through the micro-fluidic chip and the micro-flow gas pump array; according to the invention, distributed monitoring nodes are constructed, multi-node synchronous detection is realized by adopting a tunable diode laser absorption spectrum technology, and multi-position synchronous gas sampling is realized by combining a micro-fluidic chip and a micro-flow gas pump array, so that the problems that real-time and non-invasive monitoring cannot be realized and space-time resolution capability is lacked in the prior art are solved; the spatial distribution difference of the carbon monoxide concentration of different parts of the extracorporeal circulation pipeline can be obtained in real time, the dynamic law of the carbon monoxide concentration along with time change is analyzed, and more comprehensive and accurate data support is provided for medical evaluation.

An extracorporeal blood treatment apparatus (100) comprises: a treatment unit (200); an extracorporeal blood circuit (300) comprising a blood withdrawal line (301) connected to the treatment unit (200) and connectable to a first access port (A) or a second access port (B) of a patient and a blood return line (302) connected to an outlet (202) of the treatment unit (200) and connectable to the second access port (B) or the first access port (A) of the patient; a switching valve (1) in fluid communication with the blood withdrawal line (301) and the blood return line (302) and with the first access port (A) and the second access port (B), which is switchable between: (i) a first switching condition, wherein the first access port (A) and the second access port (B) are respectively fluidly connected to the blood withdrawal line (301) and the blood return line (302) to trigger a normal mode of operation; (ii) a second switching condition, wherein the first access port (A) and the second access port (B) are respectively fluidly connected to the blood return line (302) and the blood withdrawal line (301) to trigger a reversing mode of operation wherein blood coming from the patient is circulated through the treatment unit (200) according to an opposite / reverse direction and returned to the patient; (iii) a third switching condition, wherein the first access port (A) and the second access port (B) are fluidly connected to each other and the blood withdrawal line (301) and the blood return line (302) are fluidly connected to each other to trigger a recirculation mode, wherein the extracorporeal blood circuit (300) is not in fluid communication with the first (A) and the second access port (B).