34 results about "Arterial perfusion" patented technology

An atherectomy device comprising cannula systems having lumens adapted for insertion of a blood filter and an atherectomy catheter useful for performing atherectomy directly on a patient's cardiovascular tissue. Other embodiments include a lumen for arterial perfusion useful in providing oxygenated blood to the aorta during cardiopulmonary bypass. The distal end of the atherectomy catheter includes an assembly that comprises a pincer, a loop with or without a mesh, laser, hydraulics, or other suitable mechanism adapted for removing atheroma from a cardiac or vascular tissue. Methods of using the systems for vascular atherectomy are also disclosed herein.

The invention relates to a device for the perfusion of a human liver graft, which includes: (a) an upper tray which includes a container suitable for holding a liver graft in an inverted position with respect to the normal anatomical position, in contact with a preservative solution, an arterial perfusion circuit, and a portal perfusion circuit, separate from said arterial perfusion circuit; and (b) a lower console, which supports said tray and which includes a means for sending or supplying said preservative solution, a means for supplying power, a means for temperature control, a means for supplying oxygen, a means for controlling the flow rate and pressure, said tray and console being connected in a secure, removable manner, wherein said means for temperature control maintain the temperature of the liver graft between 0 ºC and 40 ºC.

The invention relates to a device for the preservation of a hepatic graft in normothermia comprising a receptacle in which said hepatic graft is housed in a preservation solution, an arterial perfusion circuit, a portal perfusion circuit, at least one flow sensor of a perfusion circuit, and at least one pressure sensor of a perfusion circuit. For the purpose of increasing the preservation of the hepatic graft, the preservation device additionally comprises an arterial oxygenator connected to the arterial perfusion circuit, a portal oxygenator connected to the portal perfusion circuit, at least one arterial perfusion pump, at least one portal perfusion pump, a temperature exchange module configured to maintain the temperature inside the receptacle in normothermia, and a pressure and flow control device.

The invention discloses a pressure control device for the arterial perfusion of an isolated vascular. The device comprises a perfusate circulatory system, a gas system, and a pressure detection and control system. The perfusate circulatory system comprises a sealed pipe; the sealed pipe is connected to a pipeline which forms a circulatory pipeline with the sealed pipe; the end of the pipeline where the perfusate inflows is inserted below the liquid level of the sealed pipe; and a peristaltic pump and the isolated vascular are arranged on the pipeline. The gas system comprises an air inlet pipeand an air outlet pipe which are connected to a cavity part of the sealed pipe, wherein the air inlet pipe is connected to an air pump and a gas flow regulating valve, and the air outlet pipe is connected to an electromagnetic exhaust valve and a gas flow regulating valve. The pressure detection and control system comprises an air pressure sensor inserted into the cavity part of the sealed pipe,a control system connected to the air pressure sensor, and a display screen connected to the control system. According to the pressure control device for the arterial perfusion of the isolated vascular, the isolated vascular can be ensured to obtain sufficient nutrients when in-vitro culture; meanwhile, the dynamic pressure fluctuation of the perfusate can be maintained to be consistent with the change rule of human body pulse wave.

The invention relates to an axillary artery cannula for achieving no perfusion ischemic areas during extracorporeal circulation period and application thereof. The axillary artery cannula comprises a cannula body with a blood supplying end, and is characterized by also comprising a proximal artery tube and a distal artery tube which communicate with the cannula body and play roles in shunting and sharing pressure, thus forming an extracorporeal circulation plastic perfusion tube of which the whole structure is T-shaped or Y-shaped, wherein an included angle is reserved between the proximal artery tube of the perfusion tube with Y-shaped structure and the cannula body of the blood supplying end to distribute and adjust blood flow volume of perfusion. The axillary artery cannula is applied to a right axillary artery to achieve systemic arterial perfusion during the extracorporeal circulation period and selective cerebral perfusion during deep hypothermic circulatory arrest, and meanwhile can avoid right upper limb ischemia. Obviously, the axillary artery cannula can meet systemic arterial perfusion during the extracorporeal circulation period and cerebral perfusion during circulatory arrest, can distribute and adjust perfusion blood flow, and achieves no perfusion ischemic areas; and the axillary artery cannula is simple and convenient to operate, easy and reliable to fix, not prone to rising perfusion pressure and causing blood leakage, less in blood damage, greatly shortened in operation time and reduced in right upper limb ischemic time.

The invention discloses a method for establishing a prognosis model for treating advanced liver cancer patients by HAIC, which comprises the following steps: (1) acquiring sample data, and screening the sample data; (2) carrying out single-factor analysis and multi-factor analysis by adopting a Cox proportional danger model, and selecting factors influencing prognosis from the sample data; (3) establishing a column graph prediction model for predicting prognosis according to the sample data and the factors influencing prognosis; and (4) verifying the column graph prediction model by adopting c-index and a correction curve. The model established by the method can evaluate the hepatic artery perfusion chemotherapy prognosis model of the local advanced liver cancer patient, and the model is displayed in the form of a column diagram, so that the model is intuitive and simple, and is convenient for clinical doctors and patients to operate and carry out individualized prediction on the patients.

The invention discloses a vena cava retroperfusion tube and a use method thereof, and belongs to the field of medical apparatuses. The vena cava retroperfusion tube comprises an arterial perfusion tube. The arterial perfusion tube is connected with an arterial perfusion branch tube A and an arterial perfusion branch tube B. The free end of the arterial perfusion branch tube A is connected with oneend of a vena cava drainage tube A. The free end of the arterial perfusion branch tube B is connected with one end of a vena cava drainage tube B. The arterial perfusion branch tube A and the vena cava drainage tube A are integrally formed, and the arterial perfusion branch tube B and the vena cava drainage tube B are integrally formed. The vena cava drainage tube A or the vena cava drainage tubeB is connected with the arterial perfusion tube through a retroperfusion tube body. The arterial perfusion branch tube A, the arterial perfusion branch tube B, vena cava drainage tube A and the venacava drainage tube B are all hoses. The vena cava retroperfusion tube has the advantages of being convenient to operate, short in preparing time and capable of being rapidly switched among various perfusion modes.

The invention relates to an axillary artery and femoral artery cannula without a perfusion ischemia area and application of the cannula. The axillary artery and femoral artery cannula comprises a cannula main body of a blood supply end; the axillary artery and femoral artery cannula is characterized by further comprising a proximal end tube and a distal end tube, the two of which are communicated with the cannula main body and have shunting and pressure dividing effects, and a plastic extracorporeal circulating perfusion tube which is formed on the overall structure and formed into a T-shaped or Y-shaped structure, wherein an included angle is formed between the proximal end tube of the perfusion tube of the Y-shaped structure and the cannula main body of the blood supply end so that the perfusion blood flow can be distributed or regulated. The axillary artery and femoral artery cannula without the perfusion ischemia area is applied to the axillary artery and the femoral artery on the right side to realize arterial perfusion of the whole body and selective cerebral perfusion of deep hypothermic circulatory arrest during extracorporeal circulation, and meanwhile, the ischemia of the right upper limb and the right lower limb can be avoided; obviously, the axillary artery and femoral artery cannula without the ischemia area is capable of realizing the distribution and control of the perfusion blood flow, and no perfusion ischemia area is formed during extracorporeal circulation; besides, the axillary artery and femoral artery cannula is convenient to operate and high in universality; the operation time can be greatly reduced so that the limb ischemia time can be reduced; in short, the axillary artery and femoral artery cannula without the perfusion ischemia area can be widely applied.

The invention relates to a transcatheter arterial perfusion system, and the system comprises an injection device, wherein the injection device comprises a first injector and an injection assembly, the injection assembly is connected with the first injector, and the injection assembly is used for setting injection parameters and pushing the first injector according to preset parameters; a detection device which comprises a second injector and a detection assembly, wherein the detection assembly is used for detecting injection parameters of the medicament; a display assembly which is in control connection with the detection device, wherein the display assembly is used for displaying the medicament injection parameters acquired by the detection device; and a microcatheter which is selectively communicated with the first injector and the second injector. According to the transcatheter arterial perfusion system, errors of medicament injection during manual injection each time are effectively reduced, and the situation that backflow occurs or the micro-catheter pops out of the artery can be avoided. Meanwhile, the labor intensity of an operation operator can be greatly reduced, and the operation efficiency and the operation curative effect are improved.

The invention provides a four-branch artificial blood vessel for arcus aortae portion replacement perfusion. The artificial blood vessel comprises a body artificial blood vessel for introducing blood for perfusion and a brachiocephalic artery branch artificial blood vessel, a left common carotid artery branch artificial blood vessel and a left subclavian artery branch artificial blood vessel which are communicated with the body artificial blood vessel. An arterial perfusion branch artificial blood vessel communicated with extracorporeal circulation is further arranged on the body artificial blood vessel. Perfusion can be performed on the bilateral whole brain and the whole body during operation, the brain perfusion during operation during profound hypothermia circulation arrest is ensured to the maximum extent, postoperative neurological complications can be reduced, the operation technique can be simplified, and the operation time is shortened, so that the purposes of improving the operation success rate and reducing related operation complications are achieved.

The invention discloses a remains preservative with detumescence, fading and deodorization functions and a preparation method thereof. The remains preservative is mainly prepared from the following raw materials in parts by volume: 10 to 40 parts of ethanol, 5 to 20 parts of glycerol, 1 to 20 parts of benzalkonium bromide, 1 to 10 parts of polyhexamethylene guanidine, 10 to 15 parts of hexamethylenetetramine, 0.2 to 10 parts of ethylparaben, 3 to 15 parts of organic acid, 5 to 10 parts of dimethyl fumarate, 0 to 0.3 part of essence, 0.5 to 3 parts of mannitol/sorbitol, 1 to 30 parts of low-toxicity metal salt and 10 to 40 parts of distilled water. According to the invention, normal remains and special remains (cardiovascular disease remains and edema remains) can be preserved and fixed by adopting arterial perfusion, intravenous perfusion, aortic arch method, left ventricle or injection method, and effective disinfection, preservation, detumescence, fading and deodorization effects are achieved; in addition, the preservative has efficient antibacterial property, can effectively inhibit the corrosion of bacteria to the remains and the autolysis of tissues, and is suitable for short-term preservation of the remains and preservation of the remains with cardiovascular diseases and edema.

The invention discloses an embalming method for fresh corpses. The method comprises the following steps: preparing a fresh corpse, and carrying out in-vitro disinfection; preparing the following materials: ammonia gas, alcohol, carbolic acid, glycerol, sodium benzoate, common perfume, industrial salt and saline water; perfusing the ammonia gas, alcohol, carbolic acid, glycerol, sodium benzoate andsaline water into the corpse from a femoral artery by a pipeline through adopting an artery perfusion technology; adding industrial salt into a storage warehouse made of PVC plastic, and then buryingthe whole corpse in the industrial salt; and finally placing the storage stock in a shady place in a whole corpse warehouse. The materials in the invention do not contain formaldehyde, inorganic oxides or organic oxides, so the embalming method has the advantages of small irritation, small harm to the environment and human health, simplicity, easily available in raw materials and strong operability, is suitable for embalming preservation of corpses, tissues and dissects in medical teaching and scientific research and funeral service work, is convenient to apply practically, and is beneficialto promotion and application.

The arterial perfusion device comprises a catheter, a connecting pipe, a radiography guide wire and a detector, a fixing plate is installed outside the radiography guide wire, and a backflow prevention mechanism is arranged in the catheter; the anti-backflow mechanism comprises blocking soft films symmetrically arranged in the guide pipe, one ends of the two blocking soft films are movably connected with the exterior of the guide pipe, the exterior of the blocking soft films are attached to the exterior of the fixing plate, and a flow adjusting mechanism is further arranged in the guide pipe; through cooperative use of a first air bag and a flow adjusting soft film in the flow adjusting mechanism, the infusion speed can be adjusted and controlled in the process of medicine infusion, liquid medicine impacts the flow adjusting soft film outwards during infusion, the flow adjusting soft film moves to the outside of a fixing plate through impact, and therefore the discharging speed of the liquid medicine is reduced, and the infusion speed is increased. In addition, the flow adjusting soft film can drive the first air bag to move in the moving process, so that the first air bag moves towards the interior of the catheter, and impact on the blood vessel in the perfusion process is avoided.

The invention relates to a carotid artery and femoral artery cannula capable of reducing ischemic time of a brain or limbs and application thereof. The carotid artery and femoral artery cannula comprises a cannula body with a blood supplying end, and is characterized by also comprising a proximal artery tube and a distal artery tube which communicate with the cannula body and play roles in shunting and sharing pressure, thus forming an extracorporeal circulation plastic perfusion tube of which the whole structure is T-shaped or Y-shaped, wherein an included angle is reserved between the proximal artery tube of the perfusion tube with Y-shaped structure and the cannula body of the blood supplying end to distribute and adjust blood flow volume of perfusion. The carotid artery and femoral artery cannula is applied to a right common carotid artery to achieve systemic arterial perfusion during the extracorporeal circulation period and selective cerebral perfusion during deep hypothermic circulatory arrest, and also applied to the femoral artery to achieve systemic arterial perfusion during the extracorporeal circulation period and meanwhile avoid lower limb ischemia. Obviously, the carotid artery and femoral artery cannula is convenient to operate, strong in universality and greatly shortened in operation time, so that ischemic time of the brain or the limbs can be greatly reduced, and success rate of aortic arch surgery is improved, and thereby carotid artery and femoral artery cannula can be widely used.

The invention relates to a Carboxy-DiI compound as well as a preparation method and application thereof; the Carboxy-DiI compound is used as a fluorescent dye with higher water solubility, is high influorescence efficiency, can be used for arterial perfusion of a living heart and uniform labeling of micro-artery vascular endothelial cells, and is good in specificity and high in sensitivity.