58 results about "Peripheral intravenous" patented technology

The invention discloses a peripheral vein puncture blood vessel pressure monitoring system for image enhancement examination based on multi-modal fusion, and relates to the technical field of medical image assistion.The peripheral vein puncture blood vessel pressure monitoring system comprises the steps that image data, sensor data and personalized data of a patient are collected; generating an image feature vector, a sensor feature vector and a personalized feature vector based on the preprocessed multi-modal data, carrying out feature interaction on a multi-modal feature line, carrying out representation fusion by combining Transform with contrast learning, and generating a fusion representation vector; the maximum tolerance pressure, the extravasation risk level and the recommended injection flow rate range of the target puncture point under the current injection flow rate are predicted and evaluated in the blood vessel pressure resistance prediction model, injection suggestions and injection alarms of the target puncture point are generated, and injection parameters are automatically adjusted. According to the method, the personalized safety pressure threshold values of patients with different blood vessel conditions are accurately evaluated, and the safety and accuracy of peripheral vein puncture are remarkably improved.

The present invention relates to the technical field of aromatherapy in traditional Chinese medicine, and specifically to an aromatherapy composition for treating peripheral phlebitis through transdermal absorption, and its preparation and application. The aromatherapy composition and its preparation of the present invention are used for transdermal treatment of peripheral superficial phlebitis through aromatherapy in traditional Chinese medicine, and the overall effective rate of 24h treatment is 100%, of which the cure rate is 55%, and the cure rate is 97.5% after 48h. The reduction of phlebitis grade is recorded as grade difference, and the sum of grade differences of 40 patients is 125. The treatment effect of peripheral superficial phlebitis is significantly superior to traditional and commonly used methods. Compared with traditional therapies, it can greatly shorten the treatment time, quickly relieve pain, reduce the incidence of complications, and has stable and reliable efficacy. Patients' compliance, comfort and acceptability during the treatment process are very good.

The invention discloses a central vein vascular access complication risk management method and related equipment. The method comprises the steps that based on basic physiological information and edema related information of a patient, ideal pressure values of different edema parts of the patient are determined through a treatment pressure decision model, and the treatment pressure decision model is obtained through training according to historical clinical treatment data; displaying the ideal pressure values of the different edema parts of the patient; in the binding process, the actual pressure value between the bandage and the skin of the patient is obtained, and the actual pressure value is displayed. The problems that in the prior art, complication supervision of a patient after a central venous catheter is implanted through a peripheral vein and infusion port implantation stays in static inquiry, the response speed is low, emergency situations cannot be recognized in time, the data collection mode is single, and the evaluation accuracy is insufficient can be solved.

The invention provides autologous platelet-containing plasma gel and a preparation method and application thereof, and relates to the technical field of biological medicine and tissue engineering.The preparation method comprises the following steps that peripheral venous blood of a patient is extracted and added into a centrifugal tube mixed with a sodium citrate anticoagulant; putting the centrifugal tube into a centrifugal machine for centrifuging, and taking upper-layer plasma; wherein the upper-layer plasma refers to plasma between the upper-layer liquid level and the lower-layer red blood cell layer by 1mm; the centrifugal speed ranges from 1300 r / min to 1700 r / min; the centrifugation time is 3-5 min; under a sterile condition, preparing a calcium gluconate / thrombin mixed solution; and dropping the calcium gluconate / thrombin mixed solution into the upper plasma, mixing, and solidifying to obtain the autologous platelet-containing plasma gel. After one-time centrifugation, upper-layer full-layer plasma is extracted, the volume of the prepared gel is far larger than that of a traditional method, the utilization rate of whole blood platelets and fibrinogen is close to 100%, and regeneration and repair of large-area tissue wounds can be met.

Embodiments of the present invention address the limitations of current central venous pressure monitoring by providing a noninvasive, non-implanted, and self-administered test for the determination of central venous pressure. Some embodiments use alterations in transmural pressure, optical measurements of venous volume, and anatomical measurements to determine central venous pressure. The system can provide an absolute measurement of central pressure and can be used to monitor relative changes in central venous pressure over time. Changes in transmural pressure are used to create detectable changes in peripheral venous vascular volume for central venous pressure measurement.

A vein simulator system can be used by clinicians to improve their proficiency in placing catheters such as PIVCs or in otherwise accessing a vasculature. A vein simulator system can include a simulated portion of a body, such as a simulated human arm, that includes at least one simulated vein. The vein simulator system can also include a control system, one or more sensors and one or more feedback components. The control system can leverage the one or more sensors to generate feedback during a clinician's attempt to place a catheter and can output the feedback via the feedback components, either during or after the attempt.

An integrated peripheral intravenous (IV) catheter configured for blood draw both at the time of catheter placement and during catheter indwell. The peripheral IV catheter includes a catheter adapter having a catheter configured to be inserted into a patient's vasculature and a side inlet defining a fluid pathway into and out of the catheter. The peripheral IV catheter also includes a side port member having a main branch, the main branch including a distal end configured to couple the side port member to the side inlet of the catheter adapter and a connector portion accessible via a proximal end of the main branch. Additionally, the peripheral IV catheter includes a blood collection adapter removably and directly coupled to the connector portion of the side port member at the proximal end of the main branch. Furthermore, side pore member of the peripheral IV catheter may include a side branch.

The invention relates to the field of preparation of CD19 targeted CAR-T cells, in particular to an adjustable CD19 targeted CAR-T cell preparation technology which comprises the following operation steps: S1, T cell collection and separation: S1.1, peripheral blood collection: blood is collected from peripheral veins of a patient, and the general collection amount is determined according to the physical condition of the patient and the amount required by subsequent cell culture and is usually between 50ml and 500ml; s1.2, performing density gradient centrifugal separation on the T cells; s2, CAR gene construction and carrier preparation: S2.1, CAR structure design (taking an inducible promoter system as an example), CD19 targeting CAR-T cells can accurately recognize and combine CD19 antigens on the surfaces of tumor cells, and as CD19 is highly expressed on the surfaces of most blood system malignant tumor cells such as B cell lymphoma and leukemia and is limited in expression in normal tissue cells, the CD19 targeting CAR-T cells can be used for accurately recognizing and combining the CD19 antigens on the surfaces of the tumor cells. Therefore, the CAR-T cells can specifically attack tumor cells like a'biological missile ', and damage to normal tissues is reduced.

1. The name of the design product: arm protection sleeve (PICC care with modular). 2. The use of the design product: for providing arm catheter protection and comfortable support for peripheral intravenous central catheter (PICC) chemotherapy patients, reducing the external force effect of daily activities and sleeping posture on the catheter. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The utility model relates to a peripheral vein indwelling needle which comprises a puncture needle assembly and an indwelling needle seat, the indwelling needle seat is of a tubular structure with two open ends, a sealing plug is installed in one end of the indwelling needle seat, the other end of the indwelling needle seat is fixedly communicated with an indwelling catheter, and the puncture needle assembly comprises a puncture needle seat. The puncture needle seat is located outside the end, away from the indwelling catheter, of the indwelling needle seat and is of a transparent tubular structure, one end of the puncture needle seat is open and provided with a detachable sealing cap, the other end of the puncture needle seat is closed, and a blood return cavity is formed between the other end of the puncture needle seat and the sealing cap. The closed end of the puncture needle base is fixedly connected with a puncture needle communicated with the interior of the blood return cavity, one end of the puncture needle is a tip end, the tip end of the puncture needle sequentially penetrates through the sealing plug and the indwelling catheter and then is located outside the indwelling catheter, and the puncture needle is in sliding connection with the sealing plug and the indwelling catheter. According to the indwelling needle, the time for medical staff to judge whether the indwelling needle is punctured into the venous blood tube of a patient or not can be shortened, so that the working efficiency of the medical staff is improved.

The present invention relates to the field of molecular biology, and more specifically to a composition, kit, and application thereof for detecting ATP7B gene polymorphisms. This method uses a PCR-based fluorescent probe melting curve method to determine common single-nucleotide polymorphisms (SNPs) in the ATP7B gene, a pathogenic gene for hepatolenticular degeneration, in genomic DNA from human peripheral venous whole blood samples. Compared to traditional PCR-based SNP detection methods, this method enables multiplexed detection within a single tube, significantly improving detection throughput. Compared to first- and second-generation sequencing methods and other methods, it offers advantages such as ease of operation, low cost, and shortened detection time.

To provide a method of administering peptide receptor radionuclide therapy for neuroendocrine tumours while minimizing gastrointestinal adverse side effects and reducing kidney function deterioration.SOLUTION: The present invention emphasizes on the use of lutetium-177 (177 Lu)-DOTATOC as a radiotherapeutic agent and arginine as the sole kidney protective agent, and intravenous infusion of the 177 Lu-DOTATOC and arginine through separate infusion lines onto different peripheral veins on opposite hands, in which the subject receiving the method of administration according to the present invention exhibits significantly and effectively reduced development of any gastrointestinal adverse events, enabling safe protection of kidneys from treatment-related injury.SELECTED DRAWING: Figure 3

Computer-implemented methods and applications for providing a user with educational guidance for peripheral IV therapy are described. In one example, a computer-implemented method for providing educational guidance for peripheral IV therapy includes displaying, on a display of a machine, a main menu including a plurality of person profiles; machine-prompting the user to select one person profile of the plurality of person profiles; machine-prompting the user to select an insertion site from a plurality of insertion sites on a person's appendage based on the selected person profile; machine-prompting the user to select a first product category from a plurality of product categories; and machine-prompting the user to select a first product of a plurality of products within the first product category, the first product being a most appropriate product of the plurality of products based at least in part on the selected person profile.

An apparatus includes a catheter, an introducer having a first member and a second member, a locking mechanism coupled to a distal end of the first member and configured to couple the introducer to a peripheral intravenous line, and an actuator coupled to the catheter. The actuator is configured to move from a first configuration, in which the catheter is disposed within the introducer, toward a second configuration to move the second member to a distal position relative to the first member. A portion of a guide of the second member being distal to the first member when the second member is in the distal position. The actuator is configured to move relative to the second member to be placed in the second configuration when the second member is in its distal position such that the catheter is disposed within and extending past an end of the peripheral intravenous line.

The invention relates to the technical field of traditional Chinese medicine aromatherapy, in particular to an aromatherapy composition for treating peripheral phlebitis through transdermal absorption as well as a preparation and application of the aromatherapy composition. According to the aromatherapy composition and the preparation thereof, the peripheral superficial phlebitis is subjected to transdermal treatment through traditional Chinese medicine aromatherapy, the total effective rate of 24-hour treatment is 100%, the cure rate is 55%, the cure rate in 48 hours is 97.5%, phlebitis grading reduction is marked as grading difference, the sum of grading differences of 40 patients is 125, and the treatment effect on the peripheral superficial phlebitis is obvious compared with that of traditional and common methods. Compared with a traditional treatment method, the traditional Chinese medicine composition can greatly shorten the treatment time, quickly relieve pain and reduce the occurrence rate of complications, the curative effect is stable and reliable, and the compliance, comfort and acceptability of a patient in the treatment process are very good.

The utility model belongs to the technical field of clinical nursing, and particularly relates to a peripheral vein central catheter dressing change support which comprises two first supporting rods and two second supporting rods, the middle portions of the two first supporting rods are correspondingly hinged to the middle portions of the two second supporting rods to form two fork-shaped structures, and the two fork-shaped structures are connected with the first supporting rods and the second supporting rods. A bearing rod is arranged between the upper ends of the two first supporting rods, a bearing rod is arranged between the upper ends of the two second supporting rods, and the two bearing rods are used for bearing arms of a patient. The telescopic mechanism is used for adjusting the included angle between the first supporting rod and the second supporting rod in the two fork-shaped structures. The puncture position and skin around the puncture position can be in a completely exposed state without manually turning or lifting the arm of a patient by a nurse, the nurse can directly clean and disinfect the skin around the puncture position in all directions, the operation convenience and efficiency are improved, the whole body can be folded, and the operation is convenient. Nursing personnel can conveniently carry along with other instruments or operation articles and go to wards for use, labor is saved in use, and flexibility is higher.

The invention relates to the field of molecular biology, in particular to a composition and a kit for detecting COX20 gene polymorphism and application of the composition and the kit. The SNP site of the COX20 gene of genome DNA in a human peripheral vein whole blood sample is determined by an ARMS-PCR fluorescent probe line method, and the genotype is tested and judged by two parallel tubes. Compared with a first-generation and second-generation sequencing method and other methods, the method has the advantages of simplicity in operation, low cost, short detection time and the like.

A method of predicting both lighter and heavier forms of gestational diabetes mellitus. According to the method, a pregnant woman is screened to determine the expression profiles of two or more miRNAs in the whole peripheral venous blood collected during the period from the tenth week to the thirteenth week of pregnancy, and the two or more miRNAs are selected from the following groups: miR-1-3p, miR-20a-5p, miR-20b-5p, miR-23a-3p, miR-100-5p, miR-125b-5p, miR-126-3p, miR-181a-5p, miR-195-5p, miR-499a-5p and miR-574-3p.

A fluid transfer device including a catheter, an introducer adapted to attach the device to a peripheral intravenous line (PIV), an actuator movably coupled to the introducer, and a catheter support movably coupled to the introducer. The catheter support is positioned between the actuator and the distal end of the introducer. The actuator moves the catheter between a first position disposed within the introducer and a second position where the end of the catheter extends beyond the end of the introducer and into the PIV. The catheter support includes a rigid or collapsible tether and a hub attached to the tether and defining a passageway. The catheter extends from the actuator through the passageway of the catheter support to the distal end of the introducer. As the actuator moves the catheter, the actuator contacts the catheter support and moves the catheter support with respect to the introducer.

This invention is directed to compositions comprising bisantrene, particularly formulations of bisantrene dihydrochloride, wherein the formulations are suitable for intravenous administration into peripheral veins as well as methods for their use and methods for preparation of such compositions. The compositions according to the present invention eliminate the need to administer bisantrene by central venous catheter administration. The compositions can be used to treat malignancies and other conditions, and may be used for cardioprotection in patients undergoing chemotherapy with anthracycline-based anti-neoplastic agents. The inclusion of α-hydroxy acids in compositions according to the present invention improves the stability of such compositions and prevents precipitation of the bisantrene.

The application discloses a myocardial ischemic injury marker CAPG and application thereof. The application finds that down-regulation of CAPG expression can improve myocardial cell apoptosis and heart function after myocardial infarction by injecting AAV9-shCAPG virus into the tail vein of a mouse model of myocardial infarction. The application first discloses a new use of macrophage capping protein (CAPG) as a therapeutic target and a diagnostic target of myocardial ischemic injury, provides a new drug action target for diagnosis and treatment of myocardial ischemic injury, and has very important clinical transformation value. As a diagnostic marker of myocardial ischemic injury, CAPG can be conveniently detected by using an existing enzyme-linked immunosorbent assay kit, has the advantage of rapid detection, and can be conveniently detected by only extracting a small amount of peripheral venous blood of a patient.

The present application relates to an integrated acute central venous catheter and a peripherally inserted intravenous catheter. The catheter assembly includes a peripheral intravenous ("PIV") portion that provides rapid vascular access. The catheter assembly includes an elongated catheter body that defines a first lumen and includes a CVC portion, a transition portion, and a PIV portion. The PIV portion defines a relatively small diameter, a tapered tip, and a lumen configured to receive a needle. The needle extends through a needle entry hole that is arranged through the side wall of the catheter body and through the PIV lumen to a point beyond the distal end of the catheter body. The clinician uses the needle and PIV portion to enter the vascular system. The needle is then removed, and a guide wire is advanced into the vascular system through the lumen of the catheter body and the PIV portion. The CVC portion is then advanced into the vascular system over the guide wire, causing the insertion site to self-expand as the transition portion enters the vascular system.

1. The name of the product of this design: tearable sheath. 2. Purpose of the product of this design: Used for short-term (less than 30 days) access to the peripheral venous system through peripheral vein puncture for infusion and intravenous treatment. 3. The design key point of this appearance design product lies in the shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The utility model relates to a peripheral venous pressure monitoring device which comprises a hose (1) and an infusion nipple (2) arranged at the bottom end of the hose (1) and used for being connected with an indwelling needle, a closed normal saline storage portion (3) is arranged in the hose (1), and scales (4) are arranged on the side wall, located below the normal saline storage portion (3), of the hose (1). And the hose (1) is provided with a telescopic turning part (10) below the scales (4). Compared with the prior art, the peripheral venous pressure monitoring device provided by the utility model is convenient for medical staff to operate, and is convenient to carry and operate. When the disposable puncture needle is used, puncture operation is not needed, and pain of a patient is relieved. The pre-sealed normal saline also reduces the possibility of contamination during operation. And the bent part of the hose can be effectively prevented from being blocked, and data are more reliable and easy to obtain.

1. The name of the design product: central venous catheter fixing patch (waterproof PICC). 2. The use of the design product: the fixing patch for peripherally inserted central catheter is used for buffering to prevent plastic accessories from damaging the skin and forming pressure sores, etc. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The present invention discloses a PICC catheterization ultrasonic puncture positioning system, belonging to the technical field of medical devices. A PICC catheterization ultrasonic puncture positioning system includes a data collection module, an identification model, and a positioning module. The present invention solves the problem that the prior art may be affected by factors such as environmental light and spatial layout, affecting its accuracy and practicability. The present invention uses Mel Frequency Cepstral Coefficients for PICC catheterization positioning, which can extract more accurate acoustic wave features, effectively identify and locate the acoustic wave signals of PICC catheterization, thereby improving the positioning accuracy, effectively reducing the interference of background noise on PICC catheterization positioning, improving the accuracy of positioning, ensuring the smooth delivery of drugs, improving the therapeutic effect of drugs, avoiding damage to surrounding tissues, reducing the occurrence of complications such as phlebitis and infection, and protecting the patient's peripheral veins from being corroded by chemotherapy drugs.

The invention discloses a tumor metastasis risk assessment method and system based on circulating tumor DNA (ctDNA) spatial heterogeneity. The core of the method is as follows: blood samples of at least two different anatomical sites (such as peripheral veins and tumor drainage veins) of the same subject are obtained at the same time, and ctDNA in the samples is subjected to sequencing analysis; calculating characteristic data (such as a relative abundance ratio) representing ctDNA spatial distribution based on the mutation abundance difference between different parts; and finally, inputting the feature data into a pre-trained metastasis risk assessment model, and outputting a quantitative tumor metastasis risk score. According to the method, the limitation of traditional single-point liquid biopsy is broken through, the detection sensitivity of tiny metastases can be remarkably improved by utilizing the spatial distribution information of the ctDNA, potential metastasis positioning information is provided, and powerful technical support is provided for accurate diagnosis and treatment decision of tumor patients.

The invention relates to the technical field of medical auxiliary instruments, in particular to an auxiliary positioning device for peripheral vein puncture, which comprises a linear motor, a positioning frame and a controller, the positioning frame is fixedly arranged on a rotor of the linear motor, the positioning frame is used for assisting vein positioning puncture, the controller is arranged on one side of a shell of the linear motor, and the controller is arranged on the other side of the shell of the linear motor. The controller is externally connected with display equipment; the positioning frame comprises a sliding block, an arc-shaped frame and an arc-shaped plate, the sliding block is fixedly connected to a rotor of the linear motor, the arc-shaped frame is rotationally connected to the sliding block, and the arc-shaped plate is fixedly arranged on the arc-shaped frame. The positioning frame is driven by the linear motor to move horizontally, the mounting block is driven by the servo motor to slide back and forth along the arc-shaped frame, the ultrasonic probe can be automatically attached to the limb curved surface for systematic scanning, and full-level and multi-dimensional vein development from subcutaneous superficial layer to deep layer blood vessels is achieved in cooperation with the ultrasonic probe and the near-infrared optical module.

This utility model relates to a tubing extraction device and a system for blood collection. The tubing extraction device is for use with a peripheral venous catheter and includes: a housing having a proximal end, a distal end, and sidewalls defining an internal volume between the proximal and distal ends; a flow tube defining an internal lumen, wherein the flow tube has a retracted position and an extended position, in which the distal end of the flow tube is received within the housing, and in the extended position, the distal end of the flow tube extends beyond the distal end of the housing; a support tube connected to and movable with the flow tube; and a collapsible support positioned within the housing, wherein a portion of the flow tube extends through the collapsible support. When the flow tube is in the retracted position, the collapsible support has a first length, and when the flow tube is in the extended position, the collapsible support has a second length, the first length being greater than the second length. The distal end of the support tube is configured such that when the tubing extraction device is connected to a needleless connector, the distal end is positioned proximal to the distal end of the needleless connector.