39 results about "Peripheral intravenous" patented technology

The invention discloses a peripheral vein puncture blood vessel pressure monitoring system for image enhancement examination based on multi-modal fusion, and relates to the technical field of medical image assistion.The peripheral vein puncture blood vessel pressure monitoring system comprises the steps that image data, sensor data and personalized data of a patient are collected; generating an image feature vector, a sensor feature vector and a personalized feature vector based on the preprocessed multi-modal data, carrying out feature interaction on a multi-modal feature line, carrying out representation fusion by combining Transform with contrast learning, and generating a fusion representation vector; the maximum tolerance pressure, the extravasation risk level and the recommended injection flow rate range of the target puncture point under the current injection flow rate are predicted and evaluated in the blood vessel pressure resistance prediction model, injection suggestions and injection alarms of the target puncture point are generated, and injection parameters are automatically adjusted. According to the method, the personalized safety pressure threshold values of patients with different blood vessel conditions are accurately evaluated, and the safety and accuracy of peripheral vein puncture are remarkably improved.

The invention discloses a central vein vascular access complication risk management method and related equipment. The method comprises the steps that based on basic physiological information and edema related information of a patient, ideal pressure values of different edema parts of the patient are determined through a treatment pressure decision model, and the treatment pressure decision model is obtained through training according to historical clinical treatment data; displaying the ideal pressure values of the different edema parts of the patient; in the binding process, the actual pressure value between the bandage and the skin of the patient is obtained, and the actual pressure value is displayed. The problems that in the prior art, complication supervision of a patient after a central venous catheter is implanted through a peripheral vein and infusion port implantation stays in static inquiry, the response speed is low, emergency situations cannot be recognized in time, the data collection mode is single, and the evaluation accuracy is insufficient can be solved.

The invention provides autologous platelet-containing plasma gel and a preparation method and application thereof, and relates to the technical field of biological medicine and tissue engineering.The preparation method comprises the following steps that peripheral venous blood of a patient is extracted and added into a centrifugal tube mixed with a sodium citrate anticoagulant; putting the centrifugal tube into a centrifugal machine for centrifuging, and taking upper-layer plasma; wherein the upper-layer plasma refers to plasma between the upper-layer liquid level and the lower-layer red blood cell layer by 1mm; the centrifugal speed ranges from 1300 r / min to 1700 r / min; the centrifugation time is 3-5 min; under a sterile condition, preparing a calcium gluconate / thrombin mixed solution; and dropping the calcium gluconate / thrombin mixed solution into the upper plasma, mixing, and solidifying to obtain the autologous platelet-containing plasma gel. After one-time centrifugation, upper-layer full-layer plasma is extracted, the volume of the prepared gel is far larger than that of a traditional method, the utilization rate of whole blood platelets and fibrinogen is close to 100%, and regeneration and repair of large-area tissue wounds can be met.

A vein simulator system can be used by clinicians to improve their proficiency in placing catheters such as PIVCs or in otherwise accessing a vasculature. A vein simulator system can include a simulated portion of a body, such as a simulated human arm, that includes at least one simulated vein. The vein simulator system can also include a control system, one or more sensors and one or more feedback components. The control system can leverage the one or more sensors to generate feedback during a clinician's attempt to place a catheter and can output the feedback via the feedback components, either during or after the attempt.

An integrated peripheral intravenous (IV) catheter configured for blood draw both at the time of catheter placement and during catheter indwell. The peripheral IV catheter includes a catheter adapter having a catheter configured to be inserted into a patient's vasculature and a side inlet defining a fluid pathway into and out of the catheter. The peripheral IV catheter also includes a side port member having a main branch, the main branch including a distal end configured to couple the side port member to the side inlet of the catheter adapter and a connector portion accessible via a proximal end of the main branch. Additionally, the peripheral IV catheter includes a blood collection adapter removably and directly coupled to the connector portion of the side port member at the proximal end of the main branch. Furthermore, side pore member of the peripheral IV catheter may include a side branch.

1. The name of the design product: arm protection sleeve (PICC care with modular). 2. The use of the design product: for providing arm catheter protection and comfortable support for peripheral intravenous central catheter (PICC) chemotherapy patients, reducing the external force effect of daily activities and sleeping posture on the catheter. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The present invention relates to the field of molecular biology, and more specifically to a composition, kit, and application thereof for detecting ATP7B gene polymorphisms. This method uses a PCR-based fluorescent probe melting curve method to determine common single-nucleotide polymorphisms (SNPs) in the ATP7B gene, a pathogenic gene for hepatolenticular degeneration, in genomic DNA from human peripheral venous whole blood samples. Compared to traditional PCR-based SNP detection methods, this method enables multiplexed detection within a single tube, significantly improving detection throughput. Compared to first- and second-generation sequencing methods and other methods, it offers advantages such as ease of operation, low cost, and shortened detection time.

Computer-implemented methods and applications for providing a user with educational guidance for peripheral IV therapy are described. In one example, a computer-implemented method for providing educational guidance for peripheral IV therapy includes displaying, on a display of a machine, a main menu including a plurality of person profiles; machine-prompting the user to select one person profile of the plurality of person profiles; machine-prompting the user to select an insertion site from a plurality of insertion sites on a person's appendage based on the selected person profile; machine-prompting the user to select a first product category from a plurality of product categories; and machine-prompting the user to select a first product of a plurality of products within the first product category, the first product being a most appropriate product of the plurality of products based at least in part on the selected person profile.

An apparatus includes a catheter, an introducer having a first member and a second member, a locking mechanism coupled to a distal end of the first member and configured to couple the introducer to a peripheral intravenous line, and an actuator coupled to the catheter. The actuator is configured to move from a first configuration, in which the catheter is disposed within the introducer, toward a second configuration to move the second member to a distal position relative to the first member. A portion of a guide of the second member being distal to the first member when the second member is in the distal position. The actuator is configured to move relative to the second member to be placed in the second configuration when the second member is in its distal position such that the catheter is disposed within and extending past an end of the peripheral intravenous line.

The invention relates to the field of molecular biology, in particular to a composition and a kit for detecting COX20 gene polymorphism and application of the composition and the kit. The SNP site of the COX20 gene of genome DNA in a human peripheral vein whole blood sample is determined by an ARMS-PCR fluorescent probe line method, and the genotype is tested and judged by two parallel tubes. Compared with a first-generation and second-generation sequencing method and other methods, the method has the advantages of simplicity in operation, low cost, short detection time and the like.

A fluid transfer device including a catheter, an introducer adapted to attach the device to a peripheral intravenous line (PIV), an actuator movably coupled to the introducer, and a catheter support movably coupled to the introducer. The catheter support is positioned between the actuator and the distal end of the introducer. The actuator moves the catheter between a first position disposed within the introducer and a second position where the end of the catheter extends beyond the end of the introducer and into the PIV. The catheter support includes a rigid or collapsible tether and a hub attached to the tether and defining a passageway. The catheter extends from the actuator through the passageway of the catheter support to the distal end of the introducer. As the actuator moves the catheter, the actuator contacts the catheter support and moves the catheter support with respect to the introducer.

This invention is directed to compositions comprising bisantrene, particularly formulations of bisantrene dihydrochloride, wherein the formulations are suitable for intravenous administration into peripheral veins as well as methods for their use and methods for preparation of such compositions. The compositions according to the present invention eliminate the need to administer bisantrene by central venous catheter administration. The compositions can be used to treat malignancies and other conditions, and may be used for cardioprotection in patients undergoing chemotherapy with anthracycline-based anti-neoplastic agents. The inclusion of α-hydroxy acids in compositions according to the present invention improves the stability of such compositions and prevents precipitation of the bisantrene.

The application discloses a myocardial ischemic injury marker CAPG and application thereof. The application finds that down-regulation of CAPG expression can improve myocardial cell apoptosis and heart function after myocardial infarction by injecting AAV9-shCAPG virus into the tail vein of a mouse model of myocardial infarction. The application first discloses a new use of macrophage capping protein (CAPG) as a therapeutic target and a diagnostic target of myocardial ischemic injury, provides a new drug action target for diagnosis and treatment of myocardial ischemic injury, and has very important clinical transformation value. As a diagnostic marker of myocardial ischemic injury, CAPG can be conveniently detected by using an existing enzyme-linked immunosorbent assay kit, has the advantage of rapid detection, and can be conveniently detected by only extracting a small amount of peripheral venous blood of a patient.

The present application relates to an integrated acute central venous catheter and a peripherally inserted intravenous catheter. The catheter assembly includes a peripheral intravenous ("PIV") portion that provides rapid vascular access. The catheter assembly includes an elongated catheter body that defines a first lumen and includes a CVC portion, a transition portion, and a PIV portion. The PIV portion defines a relatively small diameter, a tapered tip, and a lumen configured to receive a needle. The needle extends through a needle entry hole that is arranged through the side wall of the catheter body and through the PIV lumen to a point beyond the distal end of the catheter body. The clinician uses the needle and PIV portion to enter the vascular system. The needle is then removed, and a guide wire is advanced into the vascular system through the lumen of the catheter body and the PIV portion. The CVC portion is then advanced into the vascular system over the guide wire, causing the insertion site to self-expand as the transition portion enters the vascular system.

The utility model relates to a peripheral venous pressure monitoring device which comprises a hose (1) and an infusion nipple (2) arranged at the bottom end of the hose (1) and used for being connected with an indwelling needle, a closed normal saline storage portion (3) is arranged in the hose (1), and scales (4) are arranged on the side wall, located below the normal saline storage portion (3), of the hose (1). And the hose (1) is provided with a telescopic turning part (10) below the scales (4). Compared with the prior art, the peripheral venous pressure monitoring device provided by the utility model is convenient for medical staff to operate, and is convenient to carry and operate. When the disposable puncture needle is used, puncture operation is not needed, and pain of a patient is relieved. The pre-sealed normal saline also reduces the possibility of contamination during operation. And the bent part of the hose can be effectively prevented from being blocked, and data are more reliable and easy to obtain.

1. The name of the design product: central venous catheter fixing patch (waterproof PICC). 2. The use of the design product: the fixing patch for peripherally inserted central catheter is used for buffering to prevent plastic accessories from damaging the skin and forming pressure sores, etc. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention discloses a tumor metastasis risk assessment method and system based on circulating tumor DNA (ctDNA) spatial heterogeneity. The core of the method is as follows: blood samples of at least two different anatomical sites (such as peripheral veins and tumor drainage veins) of the same subject are obtained at the same time, and ctDNA in the samples is subjected to sequencing analysis; calculating characteristic data (such as a relative abundance ratio) representing ctDNA spatial distribution based on the mutation abundance difference between different parts; and finally, inputting the feature data into a pre-trained metastasis risk assessment model, and outputting a quantitative tumor metastasis risk score. According to the method, the limitation of traditional single-point liquid biopsy is broken through, the detection sensitivity of tiny metastases can be remarkably improved by utilizing the spatial distribution information of the ctDNA, potential metastasis positioning information is provided, and powerful technical support is provided for accurate diagnosis and treatment decision of tumor patients.

The invention relates to the technical field of medical auxiliary instruments, in particular to an auxiliary positioning device for peripheral vein puncture, which comprises a linear motor, a positioning frame and a controller, the positioning frame is fixedly arranged on a rotor of the linear motor, the positioning frame is used for assisting vein positioning puncture, the controller is arranged on one side of a shell of the linear motor, and the controller is arranged on the other side of the shell of the linear motor. The controller is externally connected with display equipment; the positioning frame comprises a sliding block, an arc-shaped frame and an arc-shaped plate, the sliding block is fixedly connected to a rotor of the linear motor, the arc-shaped frame is rotationally connected to the sliding block, and the arc-shaped plate is fixedly arranged on the arc-shaped frame. The positioning frame is driven by the linear motor to move horizontally, the mounting block is driven by the servo motor to slide back and forth along the arc-shaped frame, the ultrasonic probe can be automatically attached to the limb curved surface for systematic scanning, and full-level and multi-dimensional vein development from subcutaneous superficial layer to deep layer blood vessels is achieved in cooperation with the ultrasonic probe and the near-infrared optical module.

This utility model relates to a tubing extraction device and a system for blood collection. The tubing extraction device is for use with a peripheral venous catheter and includes: a housing having a proximal end, a distal end, and sidewalls defining an internal volume between the proximal and distal ends; a flow tube defining an internal lumen, wherein the flow tube has a retracted position and an extended position, in which the distal end of the flow tube is received within the housing, and in the extended position, the distal end of the flow tube extends beyond the distal end of the housing; a support tube connected to and movable with the flow tube; and a collapsible support positioned within the housing, wherein a portion of the flow tube extends through the collapsible support. When the flow tube is in the retracted position, the collapsible support has a first length, and when the flow tube is in the extended position, the collapsible support has a second length, the first length being greater than the second length. The distal end of the support tube is configured such that when the tubing extraction device is connected to a needleless connector, the distal end is positioned proximal to the distal end of the needleless connector.

The utility model provides a peripheral vein catheterization limb fixator which comprises a supporting base, a first bevel gear, a pedal wheel, a second bevel gear, a lead screw, a connecting assembly and a bearing pad, and a containing space is formed in the supporting base; the first bevel gear is rotatably arranged in the accommodating space, and a threaded hole is formed in the middle of the first bevel gear; the pedal wheel is rotatably arranged on the supporting base in a penetrating manner and extends into the accommodating space; the second bevel gear is arranged in the accommodating space and connected with the pedal wheel, and the second bevel gear is meshed with the first bevel gear; the lead screw is arranged on the supporting base in a penetrating mode in the vertical direction, and the lead screw is arranged in the threaded hole in a penetrating mode and matched with the threaded hole in a threaded mode. The connecting assembly is connected with the screw rod; the bearing pad is arranged on the connecting assembly in the mode that the angle can be rotationally adjusted, a U-shaped groove used for bearing the wrist of the patient is formed in the bearing pad, and a bandage is arranged in the U-shaped groove. The device can replace an assistant, and can assist an operator to independently disinfect the upper arm of a patient and fix the punctured limb.

The present invention discloses a peripheral venous protection stent, comprising a rotary cutting element, an ejection tube, an inner tube, a cannula funnel, a loading sheath, and an outer sheath tube, characterized in that: the rotary cutting element comprises a grinding section, a straight section, and a funnel section; the proximal end of the rotary cutting element is closed on the ejection tube, the rotary cutting element is a closed mesh cage structure, and the distal end of the rotary cutting element is a circular ring and extends to the straight section to form a closed design. The cannula funnel can be used alone or in conjunction with the rotary cutting element. The peripheral venous protection stent can avoid the risk of pulmonary embolism caused by thrombus production due to long-term catheterization during central venous catheterization via peripheral venous puncture; at the same time, it can avoid the risk of thrombus detachment during other interventional surgeries such as peripheral vascular thrombectomy and peripheral stent implantation.

A blood draw system including a blood draw device having an actuator and a blood draw tube operably coupled to the actuator, the actuator configured to selectively advance the blood draw tube through a catheter of a vascular access device when the blood draw device is coupled to the vascular access device. The system also includes an extension tube extending from the blood draw device, the proximal extension tube being in fluid communication with the blood draw tube, and a proximal connector positioned at a proximal end of the extension tube. Furthermore, the system includes an initial blood volume diversion device positioned in-line with the extension tube between the blood draw device and the proximal connector, wherein the initial blood volume diversion device includes a diversion and isolation chamber configured to receive and hold an initial volume of blood drawn through the extension tube by the blood draw device.

The invention relates to the technical field of venous indwelling catheter puncture navigation, and discloses a central venous indwelling catheter puncture auxiliary system through peripheral vein puncture. According to the system, an ultrasonic image and a dissection description text are acquired through a data acquisition and verification module; a three-dimensional blood vessel modeling module is used for carrying out spatial registration on the two blood vessels, and a three-dimensional blood vessel model containing semantic information is constructed; the anatomical variation analysis module is compared with a standard map, a variation region is automatically marked, and the puncture feasibility is evaluated; the puncture path planning module generates a target path in the feasible blood vessel model in combination with the instrument parameters, and decomposes the target path into executable steps associated with real-time ultrasonic features and specific operation instructions; and finally, the path conflict detection and navigation control module carries out calibration and sends an instruction to control the puncture auxiliary device to align. According to the method, a closed loop from objective evaluation of multi-source information fusion to programmed step navigation is realized, and the dependence on personal experience and spatial imagination of an operator is reduced.

Computer-implemented methods and applications for providing a user with educational guidance for peripheral IV therapy are described. In one example, a computer-implemented method for providing educational guidance for peripheral IV therapy includes displaying, on a display of a machine, a main menu including a plurality of person profiles; machine-prompting the user to select one person profile of the plurality of person profiles; machine-prompting the user to select an insertion site from a plurality of insertion sites on a person's appendage based on the selected person profile; machine-prompting the user to select a first product category from a plurality of product categories; and machine-prompting the user to select a first product of a plurality of products within the first product category, the first product being a most appropriate product of the plurality of products based at least in part on the selected person profile.

This invention discloses a multimodal fusion-based image enhancement examination peripheral venous puncture vascular pressure monitoring system, belonging to the field of medical image-assisted technology. The system includes: acquiring patient image data, sensor data, and personalized data; generating image feature vectors, sensor feature vectors, and personalized feature vectors based on preprocessed multimodal data; performing feature interaction on multimodal feature lines; fusing representations through Transformer combined with contrastive learning to generate a fused representation vector; using a vascular pressure tolerance prediction model to predict and assess the maximum tolerable pressure, extravasation risk level, and recommended injection flow rate range at the target puncture site under the current injection flow rate; generating injection suggestions and injection alarms for the target puncture site; and automatically adjusting injection parameters. This invention accurately assesses the personalized safe pressure threshold for patients with different vascular conditions, significantly improving the safety and accuracy of peripheral venous puncture.

1. The name of the design product: PICC puncture point protection box. 2. The use of the design product: for protecting the auxiliary protection box of the peripherally inserted central catheter (PICC). 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention discloses a targeted retina drug-loaded extracellular vesicle as well as a preparation method and application thereof. The targeted retina drug-loaded extracellular vesicle comprises a lactobacillus-derived extracellular vesicle and a retina ischemia-reperfusion injury related disease treatment drug loaded in the extracellular vesicle, the medicine for treating the diseases related to the retinal ischemia reperfusion injury is indolepropionic acid; the loading capacity of the targeted retina drug-loading extracellular vesicle to indolepropionic acid is (6-8) * 10 <-8 > microgram / particle. The drug-loaded extracellular vesicle has the advantages of high drug loading rate, good biocompatibility, good gastrointestinal tract stability, high bioavailability and good safety. Besides, the extracellular vesicles loaded with indolepropionic acid can carry related marker proteins of retinal neurons through a membrane fusion technology, and can reach an eye retina area more efficiently through peripheral vein administration.

The utility model discloses a portable peripheral venous indwelling needle maintenance tube sealing bag which comprises an S-shaped hook, an independent main space, an inner mesh bag, an outer mesh bag and a bridle, a tube sealing liquid injector can be placed in the independent main space, a nylon hook and loop fastener is sewn in the center of a bag cover, and the S-shaped hook is sewn in the middle of the back side of the bag cover. The inner mesh bag comprises a rear inner side wall mesh bag, and the front inner side wall mesh bag and the rear inner side wall mesh bag can store the venous indwelling needle and the pasting film respectively. Thus. Nursing personnel do not need to frequently return to a treatment vehicle to take articles, unnecessary walking amount is reduced, working efficiency is greatly improved, nursing articles are carried along with the bag, dissatisfaction caused by long waiting time of a patient is avoided, the articles are stored in different areas, sterile operation requirements are followed, pollution risks are reduced, hospital infection probability is reduced, and meanwhile, the nursing articles are convenient to take and carry. The tube sealing bag is simple in design, easy to clean and durable, is suitable for being popularized and used in emergency and outpatient infusion rooms and other scenes, and fully meets the requirements for convenience and standardization in nursing work.