The invention relates to an early warning device for kidney non-evident injuries. The device comprises a liquid flow pipeline, foam detectors, a central processing unit, a microflow control driving probe, a biological matrix single factor analysis module and a power source, wherein the foam detectors are arranged at the two ends of the liquid flow pipeline, the central processing unit is connected with the foam detectors, the microflow control driving device is arranged on the liquid flow pipeline and electrically connected with the central processing unit, the biological matrix single factor analysis module is in data connection with the central processing unit and is further connected with the microflow control driving probe through a pipeline, the biological matrix single factor analysis module comprises a urine specific gravity detection electrode, a beta-2-microglobulin detection electrode and a cystatin C detection electrode, the power source is connected with the central processing unit, and the central processing unit is further provided with a wireless transmission port in an integrated mode. According to the early warning device, urine can be sucked in a urine collection bag system automatically through the microflow control driving probe, detection is performed according to a preset frequency, measurement does not need to be interrupted, the detection cost is low, the informationization degree is high, convenience and rapidness are achieved, and the development potential is huge.