The invention discloses a suspension bridge anchor replaceable prestressing method and a device, wherein the method comprises: a, designing the preconditions of different phases, wherein a whole bunch of prestressing meets the endurance safety conditions of main cables and the short time status safety conditions when the n' pieces of cables are replaced and relaxed; b, latterly judging cables replacing conditions; c, the replacing type is the underpinning type with relaxed pieces less than n' pieces each time; d, cables replacing method, wherein the replacing adopts single or a plurality of pieces underpinning type, anchor removing pieces number n' is less than the number of the short time status safety conditions. The device comprises a beehive embedded pipe, a prestressing tendon, an anchor pad plate, an anchor plate, a clip, a check damper, a protection cover, a spiral reinforcement under anchor, an antisepsis grease, a hexagon steel sleeve, an anti-leakage end plate and an outer hexagon steel sleeve. The method of the invention is easy and convenient for replacements, safe and reliable, has simple structure, powerfully realizes the maintenance of the whole bunch of prestressing tendons, and greatly improves the bridges safety and reliability.