The invention provides a human-machine-environment comprehensive simulating test system for a special vehicle. The system comprises a test chamber, a control center, a six-freedom movement unit, a temperature/humidity control unit, an air pressure control unit, an air distribution unit, an occupant control unit, a vision scene unit, a sound unit, a chamber environment monitoring unit and a human engineering test unit, wherein the six-freedom movement unit, the temperature/humidity control unit, the air pressure control unit, the air distribution unit, the occupant control unit, the vision scene unit, the sound unit, the chamber environment monitoring unit and the human engineering test unit are connected with the control center. The test chamber is connected with the six-freedom movement unit. The test chamber is internally provided with the occupant control unit, the vision scene unit and the sound unit. The chamber environment monitoring unit and the human engineering testing unit are arranged at the positions which are next to the body of the occupant in the test chamber. The internal space of the test chamber is furthermore connected with the temperature/humidity control unit, the air pressure control unit and the air distribution unit so that an adjusting space for temperature, humidity, air pressure and harmful gases is formed in the test chamber. The human-machine-environment comprehensive simulating test system has a comprehensive testing capability and furthermore can more truly and effectively perform human-machine-environment comprehensive test research on a single factor and composite factors.