153 results about "Oxygenator" patented technology

The embodiment of the invention provides a continuous blood oxygen monitoring system in extracorporeal circulation and a control method thereof. The continuous blood oxygen monitoring system comprises a vein sensor, an artery sensor, a blood flow sensor, an oxygen sensor, a carbon dioxide sensor, a controller and a display, the vein sensor monitors the vein blood oxygen saturation degree; the artery sensor monitors arterial oxygen saturation and hematocrit; the blood flow sensor monitors the blood flow of the artery pipeline; the oxygen sensor monitors the oxygen concentration of the oxygenator; the carbon dioxide sensor monitors the carbon dioxide concentration of the oxygenator; the display provides an interaction control, responds to a trigger operation acting on the interaction control, sends an interaction instruction to the controller, and updates information displayed in an interaction interface according to the control of the controller; the controller receives the interaction instruction and executes processing corresponding to the interaction instruction; the processing includes controlling display information of the display; the display information comprises information corresponding to the monitoring parameters. The scheme ensures the safety and effectiveness of the treatment process.

A blood pump-oxygenator system (250A, 250B, 250C) for increasing perfusion and oxygen levels in the body of a patient (P), comprising: a blood inlet (80) and a blood outlet (90) connected to form a circuit operable as a cardiopulmonary bypass system suitable for extracorporeal treatment of the blood of the patient; a first blood pump (11) and a first oxygenator (20), wherein the first blood pump (11) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the first oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The system further comprises a second blood pump (13) and a second oxygenator (21), wherein the second blood pump (13) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the second oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The circuit comprises a first branch (101) and a second branch (102) arranged in parallel with each other, the first branch (101) accommodating the first blood pump (11) and the first oxygenator (20), and the second branch (102) accommodating the second blood pump (13) and the second oxygenator (21). The system further comprises a pump control unit (290) wherein the first and second blood pumps (11, 13) are configured to be controlled by the pump control unit (290) to increase or decrease the blood flow through the corresponding oxygenator (20, 21) by changing the proportion of the blood flow through the first and second oxygenator (20, 21).

The invention discloses a disposable isolated organ continuous oxygenation mechanical perfusion circulation system and a working method. A circulation pipeline of the circulation system is provided with a to-be-carried oxygen conveying pipeline and an oxygen-carrying perfusion pipeline; the output end of the organ low-temperature storage container is connected to the to-be-carried oxygen conveying pipeline, and the pump pipe and the oxygenator are arranged on the to-be-carried oxygen conveying pipeline; the organ transfer sleeve assembly is detachably mounted on the organ tray assembly; the organ tray assembly is arranged in a cavity of the organ low-temperature storage container; the output end of the oxygenator is connected to the oxygen-carrying perfusion pipeline, the automatic bubble separator installed on the oxygen-carrying perfusion pipeline is connected to the input end of the organ transfer sleeve assembly, and the pressure sensor is installed on the oxygen-carrying perfusion pipeline. The device has the following advantages: the device has an automatic bubble removal function; on the basis of a low-temperature mechanical perfusion function, the oxygenation function is achieved; light weight is taken into account, and portable transfer of perfusion equipment is facilitated; the method has higher safety and reliability.

The invention discloses an organ mechanical perfusion system which comprises a liquid storage container used for storing perfusion liquid; the perfusion pump is used for extracting the perfusion liquid in the liquid storage container and perfusing the organ through the perfusion pipeline; the oxygenator is used for oxygenating perfusate and organs; the temperature control module is used for maintaining the temperature of the organ and the perfusate in a set range; the main control module is used for controlling the perfusion pump and the temperature control module according to the perfusion parameters, controlling the temperature control module to place the organ in a low-temperature state in a first time period, and controlling the perfusion pump to stop perfusion action or perform slow perfusion action in the low-temperature state so as to enter a maintenance stage; and in the second time period, the temperature control module is controlled to place the organ in a normal temperature or sub-normal temperature state, and the perfusion pump is controlled to execute normal perfusion action in the normal temperature or sub-normal temperature state, so that a normal perfusion stage is started. Wherein the maintenance stage of the first time period and the normal perfusion stage of the second time period can be alternately carried out.

The invention belongs to the field of medical equipment, and provides an organ perfusion device, which comprises a liquid storage bin, a perfusion device and a control device, the organ bin is used for storing isolated organs; the pump is used for driving perfusate; the perfusion pipeline is used for perfusion of an isolated organ, is provided with two or more flow division pipelines and is used for perfusion and flow division; the temperature maintaining system is used for maintaining the perfusate and the isolated organ at different temperatures; the oxygenator is used for oxygenating the perfusate; the central control system is used for system control; the perfusion pipeline is driven by the pump to extract perfusion liquid from the liquid storage bin to perfuse the isolated organ in the organ bin. Metabolic waste can be prevented from entering circulation again through one-way perfusion, low-temperature and normal-temperature double-phase automatic switching is achieved, one-way tidal perfusion is achieved, the device structure is obviously simplified, and the overall performance such as safety, stability and portability is improved.

An oxygenation device for use with extracorporeal blood circulation is disclosed. The device includes an oxygenator housing having a blood inlet end cap having a blood inlet opening, a blood outlet end cap having a blood outlet opening, and a gas collector housing between the blood inlet opening and the blood outlet opening. The gas collector housing defines a gas compartment having a gas inlet chamber with a gas inlet port and a gas outlet chamber with a gas outlet port. Heating devices are disposed against the gas collector housing and include a first heating device in the gas inlet chamber and a second heating device in the gas outlet chamber. During operation of the oxygenation device, the heating devices heat the gas compartment.

An oxygenerator (4) has a blood side (2), a gas side (6) and a semi-permeable membrane (8), where the membrane (8) separates the blood side (2) from the gas side (6), the blood side (2) has an inlet (18) and an outlet (20), the gas side (6) has an inlet (14) and an outlet (16), and during operation of the oxygenerator (4), the gas side (6) has an inlet (14) and an outlet (16). A flow of gas flows into the inlet (14) to the outlet (16) at a gas flow rate and a flow of blood flows into the inlet (18) to the outlet (20) at a blood flow rate, where gas flowing into the inlet (14) of the gas side (6) and blood flowing into the inlet (18) of the blood side (2) flow along the membrane (8) in the same direction to their respective outlets (16, 20).

1. The name of the design product: oxygenation machine (paddle wheel type). 2. The use of the design product: oxygenation equipment for oxygenating water bodies for aquaculture. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The present invention provides an organic fluid oxygenator (10) comprising a container body (20); a first hole (21) for oxygen entry and a second hole (22) for exhaust gas exit; a third hole (23) for entry of organic fluid to be oxygenated and a fourth hole (24) for exit of oxygenated organic fluid; an oxygenation chamber (30) for oxygenating the organic fluid to be oxygenated, defined within the container body (20); and a mass (31) of capillary fibers (32) impermeable to liquids but permeable to gases, arranged parallel to each other in a first direction (X) to be wrapped by the organic fluid within the oxygenation chamber (30).

The utility model provides a portable low-temperature oxygen-carrying organ transfer box which comprises a machine shell and a cover plate, a miniature oxygen generator is installed on the machine shell, two sets of air outlet connectors are arranged on the machine shell, and the miniature oxygen generator is connected with the two sets of air outlet connectors through connecting pipes. The cover plate is rotatably connected with the shell to form a placement cavity, a storage assembly is arranged in the placement cavity, the storage assembly comprises a covering shell, a container bag and an oxygenator are arranged in the covering shell, two groups of oxygen circulation openings are formed in the container bag, one group of air outlet connectors are connected with the oxygenator, and the other group of air outlet connectors are connected with one group of oxygen circulation openings; a control panel is arranged on the machine shell, and a power supply and a main control board are installed on one side of the machine shell. According to the transfer box, the miniature oxygen generator is installed on the machine shell, the miniature oxygen generator is communicated with the oxygenator and the container bag in the storage assembly through the connecting pipe, oxygen can be supplied to organs at low temperature, accumulation of toxic metabolites of the organs is effectively avoided, and the risk of ischemia reperfusion injury is reduced.

A method for controlling carbon dioxide [CO2] removal in a device (5) for extracorporeal blood gas exchange is disclosed. The device (5) comprises an oxygenator (21) including a membrane (23) acting as a gas-liquid barrier enabling CO2 transfer between a bloodstream and a sweep gas flow through the oxygenator. The method comprises the steps of adding (S1) CO2 to the sweep gas flow upstream of the oxygenator (21) to control a degree of CO2 removal from the bloodstream by the oxygenator, determining (S2) a measure of CO2 removal by the oxygenator (21) based on a difference [ΔCCO2blood] between a measure of a pre-oxygenator content of CO2 [CCO2in] in the bloodstream upstream of the oxygenator (21) and an estimate of a post-oxygenator content of CO2 [CCO2out] in the bloodstream downstream of the oxygenator (21), and utilizing (S3) the measure of CO2 removal for improved regulation of the CO2 addition to the sweep gas flow.

Disclosed in the present invention are a disposable continuous oxygenation mechanical perfusion circulation system for ex-vivo organs and a working method. A circulation pipeline of the circulation system is provided with a deoxygenated return line and an oxygenated perfusion line; an output end of a low-temperature organ storage container is connected to the deoxygenated return line, and a pump tube and an oxygenator are arranged in the deoxygenated return line; an organ adapter sleeve assembly is detachably mounted on an organ tray assembly; the organ tray assembly is arranged in a cavity of the low-temperature organ storage container; and an output end of the oxygenator is connected to the oxygenated perfusion line, an automatic bubble separator mounted on the oxygenated perfusion line is connected to an input end of the organ adapter sleeve assembly, and a pressure sensor is mounted on the oxygenated perfusion line. The present invention has the following advantages: the ability to provide an automatic bubble removal function; having an oxygenation function in addition to a low-temperature mechanical perfusion function; being lightweight and being convenient for portable transport of a perfusion apparatus; and having higher safety and reliability.

The present application relates to hollow fiber membrane and its preparation method, membrane lung oxygenator, the membrane structure of hollow fiber membrane comprises from inside to outside: porous layer, dense layer and microstructure layer; the dense layer is arranged on the porous layer, the microstructure layer is arranged on the dense layer, the surface of the microstructure layer away from the dense layer is rough surface. The surface of the hollow fiber membrane has better anticoagulation effect, and it has longer antiplasma leakage time and better oxygenation efficiency.

The invention relates to an organ perfusion device (1), which in one embodiment comprises: a perfusion fluid container (2); an oxygenator (4) in fluid communication with the perfusion fluid container (2) by means of a deoxygenated perfusion fluid supply line (LI) comprising a pump (5); an organ container (3) in fluid communication with the oxygenator (4) by means of a primary oxygenated perfusion fluid supply line (L2) and in fluid communication with the perfusion fluid container (2) by means of a deoxygenated perfusion fluid discharge line (L7) and a seeping perfusion fluid discharge line (L8); and a set (17) of syringe pumps in fluid communication with the perfusion fluid container (2). The primary oxygenated perfusion fluid supply line (L2) comprises an arterial filter (51) in fluid communication with the perfusion fluid container (2), a perfusion fluid heat exchanger (6) with a perfusion fluid temperature sensor, a pH sensor (8), a dissolved oxygen sensor (9), a flow sensor (10) and a pressure transducer (11). The deoxygenated perfusion fluid discharge line (L7) comprises a pressure transducer (21), a throttle valve (22), a dissolved oxygen sensor (23) and a sampling unit (24). The invention also relates to an organ perfusion container (3).

This utility model belongs to the field of oxygenation machine technology, and particularly relates to a spiral propulsion oxygenation machine, including a support frame. A support plate is fixedly connected to the outer wall of the support frame. A screw is provided on the inner wall of the support frame. A lifting frame is threadedly connected to the outer wall of the screw. A support rod is screwed to the outer wall of the lifting frame. A sliding block is screwed to the bottom end of the support rod. A telescopic column penetrating inside the support plate is fixedly connected to the bottom end of the sliding block. A buoy is fixedly connected to one end of the telescopic column. A motor is fixedly connected to the bottom end of the support frame. By setting the telescopic column, the rotation of the screw drives the lifting frame to slide vertically. The sliding of the lifting frame drives the three sets of support rods to move synchronously. This allows the sliding of the lifting frame to drive the telescopic column at the bottom end of the sliding block to slide horizontally along the inner wall of the support plate through the support rod. The sliding of the telescopic column drives the buoy to slide synchronously, thereby increasing the support area of ​​the rotating disk and improving the stability of the rotating disk.

The invention belongs to the technical field of drainage devices, and discloses a pericardial effusion drainage device which comprises an extracorporeal membrane lung oxygenation therapeutic apparatus and a fixing device. The extracorporeal membrane lung oxygenation therapeutic apparatus comprises a main control table, an artificial membrane lung, a centrifugal pump and an oxygenator, an inlet and an outlet of the centrifugal pump are connected with a first catheter and a second catheter respectively, the first catheter is connected with veins of a patient, the free end of the second catheter is connected with the artificial membrane lung, the artificial membrane lung is connected with a third catheter, and the third catheter is connected with the oxygenator. The free end of the third catheter is connected with the artery or vein of the patient; a branch tube of the first catheter is connected with a hydrops catheter, the free end of the hydrops catheter is connected with a drainage tube, and the diameter of the hydrops catheter is smaller than that of the drainage tube. The technical problems that according to an existing drainage mode, effusion cannot be continuously drained, the drainage efficiency is low, the postoperative anemia risk can be increased for a patient with blood loss due to an operation, and the recovery cycle of the patient is prolonged are solved.

An apparatus (1) for determining a CO2 partial pressure value of a blood side (2) of an oxygenator (4) comprises: the oxygenator (4) having a blood side (2), a gas side (6) and a semi-permeable membrane (8), wherein the membrane (8) separates the blood side (2) from the gas side (6), the gas side (6) has an inlet (14) and an outlet (16), and, during operation of the oxygenator (4), a gas flow flows into the inlet (14) to the outlet (16) at a flow rate; a first sensor (10) configured to measure CO2 partial pressure values of the gas side (6); a control unit (12) configured to process the measured CO2 partial pressure values of the gas side (6) and to determine a CO2 partial pressure value of the blood side (2) based on the measured CO2 partial pressure values of the gas side (6), wherein the control unit (12) determines the CO2 partial pressure value of the blood side (2) by calculating a rate of change of the measured CO2 partial pressure values of the gas side (6) during operation of the oxygenator (4), and, when or after the calculated rate of change equals a predetermined rate of change value or falls within a predetermined rate of change range at a predetermined measurement interval, derives the CO2 partial pressure value of the blood side (2) from the CO2 partial pressure value of the gas side (6) measured when or after the calculated rate of change equals the predetermined rate of change value or falls within the predetermined rate of change range.

An apparatus for controlling the supply of oxygenated gas to an oxygenator (140) includes a mixing chamber (161) having an interior volume (165), multiple inlets (162a, 162b), and multiple outlets (167a, 167b). Each inlet is configured to receive a different supply gas, and each outlet is configured to convey oxygenated gas from the interior volume to the oxygenator (140). The apparatus further includes multiple inlet valves (164a, 164b), each disposed between a corresponding inlet and the interior volume of the mixing chamber, and multiple outlet valves (166a, 166b), each disposed between the interior volume of the mixing chamber and a corresponding outlet. The apparatus further includes a controller (150) configured to open and close each of the inlet valves and each of the outlet valves independently of one another.

The invention relates to the technical field of medical apparatus and instruments, and particularly discloses an integrated membrane type oxygenator which comprises a blood storage cylinder, an oxygenator body, a membrane assembly, an oxygenator cover, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe and an oxygen supply pipe, the oxygenation shell comprises a variable-temperature silk membrane structure and an oxygenation silk membrane structure from inside to outside, the fluid optimization structure is arranged in the oxygenation shell and used for optimizing the blood flowing state or purifying blood, the oxygenation shell is provided with a blood outlet pipe, the blood outlet pipe is arranged close to the lower cover, and the lower cover is provided with a water inlet pipe; by integrating the blood storage cylinder, the oxygenator body and the fluid optimization structure, the integrated function of blood storage, oxygenation and flowing or purification is achieved, the basic structure is adaptive to various clinical scenes, and the integration level and practicability of the device are improved.

A system for regulating blood flow in extracorporeal circulation, and including a blood reservoir to receive blood from a patient, an oxygenator to condition the blood, a centrifugal pump to pump the blood from the blood reservoir to the oxygenator and back to the patient, an electronic remote clamp to regulate flow of the blood, and a controller to operate in a flow control mode and a speed control mode. The controller includes an operational element to set a blood flow value in the flow control mode and to set a speed of the centrifugal pump in the speed control mode. The controller to automatically switch between the flow control mode and the speed control mode in response to one or more trigger conditions and to automatically switch between the speed control mode and the flow control mode in response to opening the electronic remote clamp.

1. The name of the design product: oxygenation machine (water wheel type). 2. The use of the design product: oxygenation equipment for oxygenating water bodies for aquaculture. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

A system for extracorporeal blood circulation, with an oxygenator (10) comprising a heat exchanger (11) designed to heat or cool blood from a patient's extracorporeal blood circulation; a reservoir (20) designed to store a heat exchange medium and connected to the heat exchanger (11); and a thermoelectric heating / cooling device (14); wherein the thermoelectric heating / cooling device (14) is connected to the reservoir (20) by means of a further heat exchanger (23) and is designed to heat or cool the heat exchange medium in the reservoir (20) by means of the further heat exchanger (23).

Device for determination of a CO2 partial pressure value on a blood side of an oxygenator having an oxygenator with a blood side, a gas side and a semipermeable membrane, wherein the membrane separates the blood side from the gas side, the gas side has an inlet and an outlet and, during operation of the oxygenator, a gas flow flows into the inlet to the outlet at a flow rate. The device also has a first sensor configured to measure CO2 partial pressure values of the gas side and a control unit configured to process the measured CO2 partial pressure values of the gas side and to determine a CO2 partial pressure value on the blood side based on the measured CO2 partial pressure values of the gas side. The control unit determines the CO2 partial pressure value on the blood side during operation of the oxygenator.

1. The name of the design product: portable fish oxygenation machine. 2. The use of the design product: oxygen machine for increasing oxygen. 3. The design points of the design product: in the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view 1.

A system for ex vivo normothermic organ preservation may include a pump configured to circulate a perfusate through a perfusion circuit, an oxygenator coupled configured to oxygenate the perfusate, a heat exchanger configured to regulate a temperature of the perfusate and an organ chamber having an internal volume configured to receive an organ. The perfusion circuit may be configured to be coupled in fluid communication with an arterial inlet into the organ. The system may also include a processor and memory having instructions that when executed by the processor cause the system to carry out a method. The method may include changing a temperature of the perfusate from an initial temperature to a normothermic temperature within a normothermic temperature range, maintaining the perfusate within the normothermic temperature range for at least one hour, receiving sensor data for perfusate parameters, and displaying the sensor data.

The application relates to an ECMO core index parameter monitoring method and a portable ECMO monitor, the application adds an intelligent monitoring function of a blood oxygen change rate on the basis of an existing ECMO system, the formed portable ECMO monitor not only has respiratory monitoring, but also has blood oxygen monitoring, can monitor the oxygenation efficiency and success rate of ECMO on blood, monitors and calculates blood oxygen entering and exiting an oxygenator, obtains a corresponding blood oxygen change rate (SpO2), and further judges whether blood oxygen meets a standard and alarms, can add oxygenation efficiency monitoring of blood oxygen of the existing ECMO, realizes efficient ECMO blood oxygen supply for patients, intuitively reflects blood oxygen change of the patients, obtains respiratory data of each ECMO device in real time, obtains blood oxygen change data, and increases the monitoring value of ECMO on patients.

1. Name of the product in this design: Disposable organ transporter. 2. Application of this design: It is used for shock absorption, support and fixation of oxygenators, ambient temperature perfusion pipelines, cold storage transport boxes and other parts. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

1. Name of the product in this design: Oxygenator. 2. Purpose of this design: An aerator for increasing the oxygen content in water within containers such as fish tanks and fish buckets. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

An apparatus for perfusing an eye or portions thereof, includes: an enclosure configured to provide physical protection to an eye or portions thereof; and a fluid flow loop extending from an outlet connection of the enclosure to an inlet connection of the enclosure, the fluid flow loop including a pump, an oxygenator, and a waveform generator; and at least one sensor operable to sense a parameter of a perfusate flowing within the fluid flow loop and generate a signal representative thereof; and a control and monitoring unit configured to receive.