89 results about "Oxygenator" patented technology

A blood pump-oxygenator system (250A, 250B, 250C) for increasing perfusion and oxygen levels in the body of a patient (P), comprising: a blood inlet (80) and a blood outlet (90) connected to form a circuit operable as a cardiopulmonary bypass system suitable for extracorporeal treatment of the blood of the patient; a first blood pump (11) and a first oxygenator (20), wherein the first blood pump (11) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the first oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The system further comprises a second blood pump (13) and a second oxygenator (21), wherein the second blood pump (13) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the second oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The circuit comprises a first branch (101) and a second branch (102) arranged in parallel with each other, the first branch (101) accommodating the first blood pump (11) and the first oxygenator (20), and the second branch (102) accommodating the second blood pump (13) and the second oxygenator (21). The system further comprises a pump control unit (290) wherein the first and second blood pumps (11, 13) are configured to be controlled by the pump control unit (290) to increase or decrease the blood flow through the corresponding oxygenator (20, 21) by changing the proportion of the blood flow through the first and second oxygenator (20, 21).

An oxygenerator (4) has a blood side (2), a gas side (6) and a semi-permeable membrane (8), where the membrane (8) separates the blood side (2) from the gas side (6), the blood side (2) has an inlet (18) and an outlet (20), the gas side (6) has an inlet (14) and an outlet (16), and during operation of the oxygenerator (4), the gas side (6) has an inlet (14) and an outlet (16). A flow of gas flows into the inlet (14) to the outlet (16) at a gas flow rate and a flow of blood flows into the inlet (18) to the outlet (20) at a blood flow rate, where gas flowing into the inlet (14) of the gas side (6) and blood flowing into the inlet (18) of the blood side (2) flow along the membrane (8) in the same direction to their respective outlets (16, 20).

The present invention provides an organic fluid oxygenator (10) comprising a container body (20); a first hole (21) for oxygen entry and a second hole (22) for exhaust gas exit; a third hole (23) for entry of organic fluid to be oxygenated and a fourth hole (24) for exit of oxygenated organic fluid; an oxygenation chamber (30) for oxygenating the organic fluid to be oxygenated, defined within the container body (20); and a mass (31) of capillary fibers (32) impermeable to liquids but permeable to gases, arranged parallel to each other in a first direction (X) to be wrapped by the organic fluid within the oxygenation chamber (30).

The utility model provides a portable low-temperature oxygen-carrying organ transfer box which comprises a machine shell and a cover plate, a miniature oxygen generator is installed on the machine shell, two sets of air outlet connectors are arranged on the machine shell, and the miniature oxygen generator is connected with the two sets of air outlet connectors through connecting pipes. The cover plate is rotatably connected with the shell to form a placement cavity, a storage assembly is arranged in the placement cavity, the storage assembly comprises a covering shell, a container bag and an oxygenator are arranged in the covering shell, two groups of oxygen circulation openings are formed in the container bag, one group of air outlet connectors are connected with the oxygenator, and the other group of air outlet connectors are connected with one group of oxygen circulation openings; a control panel is arranged on the machine shell, and a power supply and a main control board are installed on one side of the machine shell. According to the transfer box, the miniature oxygen generator is installed on the machine shell, the miniature oxygen generator is communicated with the oxygenator and the container bag in the storage assembly through the connecting pipe, oxygen can be supplied to organs at low temperature, accumulation of toxic metabolites of the organs is effectively avoided, and the risk of ischemia reperfusion injury is reduced.

Disclosed in the present invention are a disposable continuous oxygenation mechanical perfusion circulation system for ex-vivo organs and a working method. A circulation pipeline of the circulation system is provided with a deoxygenated return line and an oxygenated perfusion line; an output end of a low-temperature organ storage container is connected to the deoxygenated return line, and a pump tube and an oxygenator are arranged in the deoxygenated return line; an organ adapter sleeve assembly is detachably mounted on an organ tray assembly; the organ tray assembly is arranged in a cavity of the low-temperature organ storage container; and an output end of the oxygenator is connected to the oxygenated perfusion line, an automatic bubble separator mounted on the oxygenated perfusion line is connected to an input end of the organ adapter sleeve assembly, and a pressure sensor is mounted on the oxygenated perfusion line. The present invention has the following advantages: the ability to provide an automatic bubble removal function; having an oxygenation function in addition to a low-temperature mechanical perfusion function; being lightweight and being convenient for portable transport of a perfusion apparatus; and having higher safety and reliability.

The present application relates to hollow fiber membrane and its preparation method, membrane lung oxygenator, the membrane structure of hollow fiber membrane comprises from inside to outside: porous layer, dense layer and microstructure layer; the dense layer is arranged on the porous layer, the microstructure layer is arranged on the dense layer, the surface of the microstructure layer away from the dense layer is rough surface. The surface of the hollow fiber membrane has better anticoagulation effect, and it has longer antiplasma leakage time and better oxygenation efficiency.

The invention relates to an organ perfusion device (1), which in one embodiment comprises: a perfusion fluid container (2); an oxygenator (4) in fluid communication with the perfusion fluid container (2) by means of a deoxygenated perfusion fluid supply line (LI) comprising a pump (5); an organ container (3) in fluid communication with the oxygenator (4) by means of a primary oxygenated perfusion fluid supply line (L2) and in fluid communication with the perfusion fluid container (2) by means of a deoxygenated perfusion fluid discharge line (L7) and a seeping perfusion fluid discharge line (L8); and a set (17) of syringe pumps in fluid communication with the perfusion fluid container (2). The primary oxygenated perfusion fluid supply line (L2) comprises an arterial filter (51) in fluid communication with the perfusion fluid container (2), a perfusion fluid heat exchanger (6) with a perfusion fluid temperature sensor, a pH sensor (8), a dissolved oxygen sensor (9), a flow sensor (10) and a pressure transducer (11). The deoxygenated perfusion fluid discharge line (L7) comprises a pressure transducer (21), a throttle valve (22), a dissolved oxygen sensor (23) and a sampling unit (24). The invention also relates to an organ perfusion container (3).

This utility model belongs to the field of oxygenation machine technology, and particularly relates to a spiral propulsion oxygenation machine, including a support frame. A support plate is fixedly connected to the outer wall of the support frame. A screw is provided on the inner wall of the support frame. A lifting frame is threadedly connected to the outer wall of the screw. A support rod is screwed to the outer wall of the lifting frame. A sliding block is screwed to the bottom end of the support rod. A telescopic column penetrating inside the support plate is fixedly connected to the bottom end of the sliding block. A buoy is fixedly connected to one end of the telescopic column. A motor is fixedly connected to the bottom end of the support frame. By setting the telescopic column, the rotation of the screw drives the lifting frame to slide vertically. The sliding of the lifting frame drives the three sets of support rods to move synchronously. This allows the sliding of the lifting frame to drive the telescopic column at the bottom end of the sliding block to slide horizontally along the inner wall of the support plate through the support rod. The sliding of the telescopic column drives the buoy to slide synchronously, thereby increasing the support area of ​​the rotating disk and improving the stability of the rotating disk.

An apparatus (1) for determining a CO2 partial pressure value of a blood side (2) of an oxygenator (4) comprises: the oxygenator (4) having a blood side (2), a gas side (6) and a semi-permeable membrane (8), wherein the membrane (8) separates the blood side (2) from the gas side (6), the gas side (6) has an inlet (14) and an outlet (16), and, during operation of the oxygenator (4), a gas flow flows into the inlet (14) to the outlet (16) at a flow rate; a first sensor (10) configured to measure CO2 partial pressure values of the gas side (6); a control unit (12) configured to process the measured CO2 partial pressure values of the gas side (6) and to determine a CO2 partial pressure value of the blood side (2) based on the measured CO2 partial pressure values of the gas side (6), wherein the control unit (12) determines the CO2 partial pressure value of the blood side (2) by calculating a rate of change of the measured CO2 partial pressure values of the gas side (6) during operation of the oxygenator (4), and, when or after the calculated rate of change equals a predetermined rate of change value or falls within a predetermined rate of change range at a predetermined measurement interval, derives the CO2 partial pressure value of the blood side (2) from the CO2 partial pressure value of the gas side (6) measured when or after the calculated rate of change equals the predetermined rate of change value or falls within the predetermined rate of change range.

A system for regulating blood flow in extracorporeal circulation, and including a blood reservoir to receive blood from a patient, an oxygenator to condition the blood, a centrifugal pump to pump the blood from the blood reservoir to the oxygenator and back to the patient, an electronic remote clamp to regulate flow of the blood, and a controller to operate in a flow control mode and a speed control mode. The controller includes an operational element to set a blood flow value in the flow control mode and to set a speed of the centrifugal pump in the speed control mode. The controller to automatically switch between the flow control mode and the speed control mode in response to one or more trigger conditions and to automatically switch between the speed control mode and the flow control mode in response to opening the electronic remote clamp.

A system for extracorporeal blood circulation, with an oxygenator (10) comprising a heat exchanger (11) designed to heat or cool blood from a patient's extracorporeal blood circulation; a reservoir (20) designed to store a heat exchange medium and connected to the heat exchanger (11); and a thermoelectric heating / cooling device (14); wherein the thermoelectric heating / cooling device (14) is connected to the reservoir (20) by means of a further heat exchanger (23) and is designed to heat or cool the heat exchange medium in the reservoir (20) by means of the further heat exchanger (23).

Device for determination of a CO2 partial pressure value on a blood side of an oxygenator having an oxygenator with a blood side, a gas side and a semipermeable membrane, wherein the membrane separates the blood side from the gas side, the gas side has an inlet and an outlet and, during operation of the oxygenator, a gas flow flows into the inlet to the outlet at a flow rate. The device also has a first sensor configured to measure CO2 partial pressure values of the gas side and a control unit configured to process the measured CO2 partial pressure values of the gas side and to determine a CO2 partial pressure value on the blood side based on the measured CO2 partial pressure values of the gas side. The control unit determines the CO2 partial pressure value on the blood side during operation of the oxygenator.

A system for ex vivo normothermic organ preservation may include a pump configured to circulate a perfusate through a perfusion circuit, an oxygenator coupled configured to oxygenate the perfusate, a heat exchanger configured to regulate a temperature of the perfusate and an organ chamber having an internal volume configured to receive an organ. The perfusion circuit may be configured to be coupled in fluid communication with an arterial inlet into the organ. The system may also include a processor and memory having instructions that when executed by the processor cause the system to carry out a method. The method may include changing a temperature of the perfusate from an initial temperature to a normothermic temperature within a normothermic temperature range, maintaining the perfusate within the normothermic temperature range for at least one hour, receiving sensor data for perfusate parameters, and displaying the sensor data.

The application relates to an ECMO core index parameter monitoring method and a portable ECMO monitor, the application adds an intelligent monitoring function of a blood oxygen change rate on the basis of an existing ECMO system, the formed portable ECMO monitor not only has respiratory monitoring, but also has blood oxygen monitoring, can monitor the oxygenation efficiency and success rate of ECMO on blood, monitors and calculates blood oxygen entering and exiting an oxygenator, obtains a corresponding blood oxygen change rate (SpO2), and further judges whether blood oxygen meets a standard and alarms, can add oxygenation efficiency monitoring of blood oxygen of the existing ECMO, realizes efficient ECMO blood oxygen supply for patients, intuitively reflects blood oxygen change of the patients, obtains respiratory data of each ECMO device in real time, obtains blood oxygen change data, and increases the monitoring value of ECMO on patients.

1. Name of the product in this design: Disposable organ transporter. 2. Application of this design: It is used for shock absorption, support and fixation of oxygenators, ambient temperature perfusion pipelines, cold storage transport boxes and other parts. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

1. Name of the product in this design: Oxygenator. 2. Purpose of this design: An aerator for increasing the oxygen content in water within containers such as fish tanks and fish buckets. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

An apparatus for perfusing an eye or portions thereof, includes: an enclosure configured to provide physical protection to an eye or portions thereof; and a fluid flow loop extending from an outlet connection of the enclosure to an inlet connection of the enclosure, the fluid flow loop including a pump, an oxygenator, and a waveform generator; and at least one sensor operable to sense a parameter of a perfusate flowing within the fluid flow loop and generate a signal representative thereof; and a control and monitoring unit configured to receive.

A veno-arterial extracorporeal membrane oxygenation system includes a dual lumen drainage cannula configured for withdrawing blood from a patient's vasculature in a manner that provides a perfusion of oxygenated blood with reduced carbon dioxide content while unloading the left ventricle, with two points of access to the patient's vasculature. The dual lumen drainage cannula has a first drainage tube and a second drainage tube co-axially aligned with the first drain-age tube. The first and second drainage tubes are fluidly coupled to a connector. A blood pump having a pump inlet is configured for fluidly connecting with the connector, while an oxygenator having an oxygenator inlet is configured for fluidly connecting with a pump outlet. An infusion cannula is configured for fluidly connecting with an oxygenator outlet for infusing oxygenated blood into a patient's bloodstream.

The application discloses an ex vivo heart perfusion system and a perfusion control method, wherein the perfusion system comprises: an organ bin, which is externally provided with a constant temperature heating film for controlling the temperature in the organ bin to be a first preset temperature threshold; a liquid storage container for containing a perfusion medium, an outlet end of the liquid storage container being connected to a first active branch vein through a first liquid supply pipe and connected to a pulmonary vein through a second liquid supply pipe, an inlet end of the liquid storage container being connected to a second active branch vein through a first liquid return pipe and connected to a pulmonary artery through a second liquid return pipe; a circulating pump connected to the first liquid supply pipe; an oxygenator connected to the first liquid supply pipe, the oxygenator being connected with a gas supply module for adjusting the gas mixing ratio in the perfusion medium; and an injection pump group for supplementing injection of nutrient substances or therapeutic drugs. The application can effectively prolong the heart supply storage time, reduce the heart supply discard rate, and further improve the utilization rate of the heart supply.

A blood pump-oxygenator system for increasing perfusion and oxygen level in a patient comprises a blood flow inlet and outlet forming a circuit operable as a cardiopulmonary bypass system for extracorporeal processing of blood, a first blood pump and first oxygenator. The first blood pump conveys blood through the circuit from the patient into the blood flow inlet, through the first oxygenator and out of the blood flow outlet back into the patient. The system further comprises a second blood pump and second oxygenator. The second blood pump conveys blood through the circuit from the patient into the inlet, through the second oxygenator and out of the outlet back into the patient. A pump control unit controls the first and second pumps to increase or decrease blood flow rate through the respective oxygenator to vary a ratio of flow rates of blood through the first and second oxygenators.

A system for calculating cardiac output of a patient on an extracorporeal blood oxygenation circuit, such as veno-venous extracorporeal membrane oxygenation, includes determining (i) a first arterial carbon dioxide content or surrogate and (ii) a first carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the first removal rate of carbon dioxide from the blood; establishing a second removal rate of carbon dioxide from the blood in the oxygenator in the extracorporeal blood oxygenation circuit; determining (i) a second arterial carbon dioxide content or surrogate and (ii) a second carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the second removal rate of carbon dioxide from the blood; and calculating a cardiac output of the patient corresponding to a blood flow rate through the extracorporeal blood oxygenation circuit, the first arterial carbon dioxide content or surrogate, the first carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the first removal rate of carbon dioxide from the blood; the second arterial carbon dioxide content or surrogate and the second carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the second removal rate of carbon dioxide from the blood.

1. The name of the design product: air suspension oxygenation machine. 2. The use of the design product: for oxygenation in aquaculture. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view. 5. The bottom view has been shown in the reference drawing, and the bottom view is omitted. 6. Other circumstances that need to be explained: part A is transparent material.

The present application relates to the technical field of medical devices, and particularly discloses an oxygenator. The oxygenator has a blood inlet on the upper part of the shell, a blood outlet on the lower part of the shell, and a heating module and the inner side wall of the shell form an outflow channel. Blood enters the outflow channel after passing through the oxygenation module and the heating module in sequence through the blood inlet, and then is discharged through the blood outlet. The blood flow rate at both ends of the heating module is relatively low, and at least one end of the heating module is in contact with the inner side wall of the shell in the circumferential direction, so that the thrombus formed in the low-speed area adheres to the heating module, and the thrombus cannot flow into the human body with the blood.

The present application relates to a kind of medical equipment, propose a kind of mechanical perfusion preservation device of organism organ, comprising: organ bin (2) is used to accommodate organism organ and accessory blood vessel;Liquid storage bin (3) is located below the organ bin (2), for storing circulating perfusion fluid;Temperature maintaining device (4) is used to maintain the temperature of organism organ and circulating fluid;Oxygenator (5) is used to continuously oxygenate circulating perfusion fluid;Filter plug device (6) is used to filter circulating perfusion fluid;Pump (7) is pressurized to circulating perfusion fluid;Perfusion pipeline (8) is connected in sequence liquid storage bin (3), filter plug device (6) and oxygenator (5), and under the drive of pump (7), the organism organ is pressurized, circulating perfusion;The mechanical perfusion preservation device can pressurize, circulating perfusion to the aortic system of organism, can simultaneously perfuse single or multiple organism organs.The device of the present application is based on the principle of organ mechanical perfusion, using oxygenated blood or acellular component circulating fluid, multiple organs can be simultaneously perfused.

The utility model provides an integrated small animal ECMO device which comprises an integrated platform, a temperature sensor, a heater, a four-channel peristaltic pump, a liquid storage device and an external oxygenator, and a first channel pump is sequentially connected with the liquid storage device and the external oxygenator in series to form a blood input and oxygenation loop; the four-channel peristaltic pump is arranged, the functions of blood oxygenation, water circulation and constant temperature are integrated, waterway circulation is formed through the humidity control unit, the third channel pump and the fourth channel pump, a blood pipeline is wrapped by a heating water bath, the liquid temperature is monitored in real time, the liquid constant temperature is ensured, and the dispersity of components is reduced through the integrated design; multifunctional integration is realized, the compound requirements of small animal experiments are met, and the experiment efficiency is improved.

The application provides a mouth-sucking oxygen inhaler, which comprises a mask, a mouthpiece fixed on the mask, and an oxygen supplier connected with the air inlet end of the mouthpiece; the oxygen supplier comprises a gas mixing chamber connected with the air inlet end of the mouthpiece, a positive pressure pure oxygen chamber connected with the air inlet end of the gas mixing chamber, a crank switch gas valve assembly arranged in the gas mixing chamber, and a flow regulating assembly arranged in the positive pressure pure oxygen chamber; the sidewall of the gas mixing chamber is provided with an ordinary air inlet connected with the outside and a pure oxygen inlet connected with the positive pressure pure oxygen chamber; the crank switch gas valve assembly comprises an arc-shaped crank, an air inlet sealing block fixed on one end of the arc-shaped crank, and an oxygen inlet sealing block fixed on the other end. The application can effectively control the oxygen concentration and prevent the oxygen from directly entering the human body, thereby improving the health during use.

A system (100, Figure 1) for controlling blood oxygenation in a patient using an oxygenator 200, the system having a controller (150, Figure 1) configured to control a gas supply apparatus (300, Figur

The utility model discloses a kind of connecting float for aquaculture oxygenator, it is related to the technical field of oxygenator, solve the oxygenator when carrying, due to the length of fixed rod is not adjustable, in the carrying process, it is relatively large to occupy space, lead to the carrying of oxygenator is not convenient, while float to multiple single individual, when installing, it needs to be positioned one by one, reduce the installation efficiency of the float problem, including oxygenator and float, the lower end of the oxygenator is fixed with support column, the sidewall of support column is equidistantly fixed and installed with multiple upper telescopic rods, the output shaft end of telescopic rod is rotatably sleeved with threaded rod, the float is sleeved on the outside of oxygenator, the upper end of the float is fixedly installed with support ring, by the integrative machine of the float being set, when installing, utilize a threaded rod to be screw-connected in the inside of a threaded hole, the threaded hole of other position can be positioned conveniently, convenient for installation.

The invention relates to the technical field of deaerator dead steam heat recovery, and discloses a heat supply deaerator dead steam heat recovery device which comprises a deaerator, the bottom of the deaerator is fixedly connected with a supporting seat, the top of the deaerator is fixedly connected with an exhaust pipe, the top of the deaerator is communicated with a transmission pipe, and the transmission pipe is communicated with the supporting seat. The end, away from the deaerator, of the conveying pipe communicates with a water supply device. The deaerator is subjected to water supply treatment through communication of the water supply device and the conveying pipe, desalted water enters the deaerator and is fully heated and deoxidized with steam, waste gas generated by the deaerator can enter the elbow through the exhaust pipe, and at the moment, part of steam can also enter the elbow along with the waste gas; the steam and the waste gas can enter the connecting pipe through the treatment frame and can enter the circulating pipe to flow in a circular ring shape, at the moment, heat carried in the steam can be concentrated in the recycling frame when flowing in the circulating pipe, and the recycling frame can heat the water supply device through the recycled heat.