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37results about How to "Significant improvement" patented technology

Research report generation method based on natural language processing

PendingCN122655689Aavoid enteringEliminate distraction issuesTimestampEngineering
The application discloses a research report generation method based on natural language processing and relates to the technical field of intelligent document analysis and generation, which comprises the following steps: version storage of source documents and generation of timestamp snapshots; paragraph-level and sentence-level segmentation of the timestamp snapshots and extraction of evidence segments carrying original text positioning indexes; core claim extraction of the evidence segments to generate conclusion units containing claim texts and confidence; establishment of the association relationship between the conclusion units and the evidence segments; generation of chapter texts according to the associated conclusion units and calculation of evidence segment coverage; and structural adjustment and regeneration of the texts when the evidence segment coverage is lower than a preset threshold. The method realizes evidence traceability, multi-type semantic association and automatic optimization based on coverage feedback.
Owner:BEIJING ZHENLI HENGYUAN TECHNOLOGY CO LTD

Creep life prediction method for nickel-based single crystal alloys considering primary orientation angle

PendingCN122511453AEasy CalibrationSimplify mathematical expressionsElement modelSingle crystal
The application discloses a creep life prediction method for a nickel-based single crystal alloy considering a primary orientation deviation angle, and comprises the following steps: S1, acquiring a primary orientation deviation angle of a sample; S2, performing a creep test on the sample to obtain creep test data; S3, establishing a creep constitutive damage equation, constructing a correlation formula of a primary orientation deviation angle influence factor and the primary orientation deviation angle, and introducing the primary orientation deviation angle influence factor into a material degradation term in the creep constitutive damage equation for correction; S4, calibrating undetermined parameters in the corrected creep constitutive damage equation by using the creep test data; and S5, establishing a finite element model of a nickel-based single crystal high-temperature alloy sample based on the calibrated creep constitutive damage equation, and calculating the creep life of the sample by using the finite element method. The application changes the influence of the primary orientation deviation on the creep life from "systematic theory coupling" to "engineering precise quantification", and is more suitable for actual engineering application requirements.
Owner:AECC HUNAN AVIATION POWERPLANT RES INST

Application of common turnip in product for inhibiting gastrointestinal helicobacter pylori

The invention belongs to the technical field of special medical food, and relates to application of common turnip in products for inhibiting gastrointestinal tract helicobacter pylori. The common turnip extract has the function of treating or preventing helicobacter pylori infection, has a good improvement effect on prevention and inhibition of gastroenteritis caused by helicobacter pylori, remarkably improves the function of a digestive system, and can be used for preventing and treating the gastroenteritis caused by the helicobacter pylori and preventing and treating the gastroenteritis caused by the helicobacter pylori. And support is provided for developing novel dietary nutrition supplements, functional foods, special medical foods and pharmaceutical compositions for inhibiting helicobacter pylori. The invention further discloses a synergistic effect of a medicinal and edible composition formed by combining the common turnip extract with extracts of clove, codonopsis pilosula, hericium erinaceus, fructus amomi and the like on inhibition of helicobacter pylori, and a greater effect of inhibiting the activity of the helicobacter pylori can be achieved. The novel product for inhibiting helicobacter pylori developed by the invention has both safety and effectiveness, and has a very good application prospect.
Owner:YANGZHOU UNIV

Pharmaceutical composition for treating corpus luteum insufficiency type infertility as well as preparation method and application of pharmaceutical composition

The invention discloses a pharmaceutical composition for treating corpus luteum insufficiency type infertility as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The technical problem to be solved is to provide the pharmaceutical composition for treating the LPD type infertility, which is simpler in formula, lower in cost and better in treatment effect. According to the technical scheme, the pharmaceutical composition is prepared from the following raw materials: codonopsis pilosula, astragalus membranaceus, fried rhizoma atractylodis macrocephalae, angelica sinensis, semen cuscutae, fried eucommia ulmoides, fried teasel root, honey-fried licorice root, processed radix aconiti carmichaeli and cornu cervi degelatinatum. The pharmaceutical composition provided by the invention can improve ovarian injury, ferroptosis phenomenon, embryo implantation disorder, uterine artery blood perfusion and the like caused by LPD, and is helpful for various pathological problems related to LPD.
Owner:ANHUI MEDICAL UNIV

Coating porous web with coating on both sides using web positioning elements

In a first aspect, the present invention relates to a coating apparatus (41, 42) for double-sided coating of a porous web (10) with a coating material (30), comprising: (i) a groove coating head (50) including an upper lip (51), a lower lip (52) and a groove (53) between the upper lip (51) and the lower lip (52); (ii) an opposing element (60) arranged across a reference plane (15) and opposite to the lower lip (52); and (iii) a slit (70) defined between the lower lip (52) and the opposing element (60) for allowing the porous web (10) to pass through it. The slot (53) opens toward the slit (70), and (iv) the web positioning elements (51, 61); wherein the web positioning elements (51, 61) are the upper lip (51) of the slot die coating head (50) or the spacer structure (61) on the opposing element (60), the upper lip (51) protruding to the reference plane (15) such that there is an offset (d) between the upper lip (51) and the lower lip (52), and the spacer structure (61) protruding to the reference plane (15) such that there is an offset (d) between the spacer structure (61) and the opposing element (60).
Owner:MMM INNOVATIONS BV

Microcapsules comprising a peptide having cell receptor binding ability and cosmetic compositions comprising the same

ActiveCN115925787BExcellent selective binding abilitygood physical and chemical stabilityCosmetic preparationsPeptide/protein ingredients
Disclosed in the present specification are a peptide having cell receptor binding ability, a microcapsule linked to the peptide, and a cosmetic composition containing the same. The peptide of an embodiment of the present invention has excellent selective binding ability to a target, and the microcapsule has excellent physicochemical stability. Therefore, the cosmetic composition containing the microcapsule linked to the peptide has excellent delivery efficiency to target cells of an effective ingredient contained in the capsule, and excellent skin condition improvement effect.
Owner:KOLMAR KOREA

Super-hydrophobic PVDF-UiO-66-PFOC composite membrane as well as preparation method and application thereof

PendingCN121846922AExcellent superhydrophobic propertiesExcellent long-lasting anti-wetting propertiesMembranesSemi-permeable membranesSeparation technologyMetal-organic framework
The invention belongs to the technical field of membrane separation, and discloses a super-hydrophobic PVDF-UiO-66-PFOC composite membrane as well as a preparation method and application thereof.The super-hydrophobic PVDF-UiO-66-PFOC composite membrane is characterized in that a PVDF hollow fiber membrane is used as a substrate, and carboxyl active sites are introduced through alkali treatment and oxidation treatment; a UiO-66-NH2 metal organic framework layer with CO2 affinity is grown on the surface of the membrane through an in-situ hydrothermal synthesis method, so that the surface roughness and the CO2 adsorption capacity are improved; furthermore, a specific fluorination reagent PFOC (perfluorooctanoyl chloride) is grafted to the amino group of the UiO-66-NH2 through nucleophilic addition reaction, so that a chemically bonded super-hydrophobic fluorination layer is formed, and the surface energy is remarkably reduced. The prepared composite membrane has high wettability resistance, high CO2 selectivity and long-term operation stability. The composite membrane can be widely applied to CO2 capture systems in the fields of coal-fired power plants, chemical plants and the like, has high absorption efficiency, long-acting wetting resistance and operation stability, is different from an MOF modified membrane for oil-water separation or general gas separation in the prior art, and has remarkable economic and environment-friendly benefits.
Owner:TIANJIN POLYTECHNIC UNIV

Application of fructus cannabis protein hydrolysate in prevention and treatment of ulcerative colitis

The invention relates to a fructus cannabis protein hydrolysate and application thereof in preventing and treating ulcerative colitis and intestinal barrier dysfunction.
Owner:TSINGHUA SHENZHEN INTERNATIONAL GRADUATE SCHOOL

Light fastness improving agent for acid dye as well as preparation method and application of light fastness improving agent

PendingCN121951944ADoes not affect color lightSignificant improvementFibre typesDyeing processUv absorbanceAfter treatment
The invention discloses a light fastness improver for an acid dye as well as a preparation method and application of the light fastness improver. The light fastness improver is prepared from the following components in parts by mass: 30 to 72 parts of benzotriazole or triazine ultraviolet absorbent; 5-25 parts of a dispersant; 1-6 parts of a solvent; and the balance of water. The preparation method comprises the following steps: firstly, uniformly mixing the dispersing agent, the solvent and the water, adding the mixture into the ultraviolet absorbent, putting the mixture into a mixing kettle or a grinding machine, and stirring and mixing for 0.5-2 hours or grinding for 4-8 hours at room temperature to prepare the light fastness improving agent. The light fastness improver disclosed by the invention is attached and permeated on a fabric for dyeing an acid dye through a dyeing one-bath method or a padding method, so that the light fastness of the fabric is obviously improved. And after treatment, the influence on after-finishing processing is small.
Owner:NICCA CHEM CHINA CO LTD

Acne skin relieving gel containing swallow and folium artemisiae argyi components and preparation method of acne skin relieving gel

PendingCN121818488AImprove anti-allergic and antioxidant propertiesEnhanced barrier functionCosmetic preparationsToilet preparationsBiotechnologyAvena sativa Kernel
The present invention relates to the technical field of skin care products, and discloses an acne skin relieving gel containing swallow and folium artemisiae argyi components, the acne skin relieving gel comprises the following components by weight: 2-3% of an oat kernel extract; 2%-3% of a folium artemisiae argyi extract; 5%-8% of a humectant; 0.5%-0.8% of an antioxidant; 0.1% to 0.2% of matrine; 4.65% to 7.4% of a skin conditioning agent; according to the invention, the oat kernels and the folium artemisiae argyi extract are compounded, so that the anti-allergy and anti-oxidation performance is synergistically improved, and redness, stabbing pain and inflammation are effectively relieved. The composite moisturizing system is combined with natural components, so that double effects of water absorption and water locking are realized, and dryness and roughness are improved permanently. All the components are natural and mild, do not contain artificial essence, pigment or preservative, and are suitable for sensitive skin. The preparation process is simple and controllable, high in batch stability and suitable for large-scale production.
Owner:BEIJING WUKONG INTERNATIONAL BEAUTY CO LTD

A method for tracing sources of urban rainstorm waterlogging multi-source pollution based on bidirectional dynamic coupling

ActiveCN122287475BHigh precisionSolving Analog Distortion Issues
The application discloses a kind of urban rainstorm waterlogging multi-source pollution tracing methods based on two-way dynamic coupling, first, the acquisition of multi-source data is carried out, then two-dimensional shallow water equation solver ANUGA calculation domain is constructed and initialized, that is, the initialization of surface water dynamic model is completed, then two-way dynamic coupling model of surface and pipe network is constructed;Subsequently, water quality transport analysis is carried out, and by building a pollution source fingerprint library, the qualitative identification and quantitative tracing analysis of pollution source are completed based on multi-pollution source water quality tracing model.The application realizes the whole-chain integrated simulation and analysis of surface water dynamics, drainage pipe network hydraulics, water quality transport and pollution tracing, solves the problems of model decoupling, water quality dimension loss, imperfect tracing method and lack of systematic tracing framework, and meets the engineering needs of high-precision, real-time sewage tracing under urban rainstorm waterlogging scenario.
Owner:UNIV OF SCI & TECH OF CHINA

Application of chrysin in preparation of medicine for treating primary sjogren's disease

PendingCN122251390ASignificant improvementsynergisticOrganic active ingredientsImmunological disordersHydroxychloroquineSjogren's disease
The application discloses application of chrysin in preparation of a medicine for treating primary Sjogren's syndrome and belongs to the technical field of biological medicine. The application proves that chrysin can be specifically combined with TNFR2 protein and is a new type of TNFR2 inhibitor through molecular docking, molecular dynamics simulation, CETSA experiment and SPR experiment. Animal experiments show that chrysin can significantly increase the secretion amount of saliva and tear of a mouse model of primary Sjogren's syndrome, reduce the serum SSA and SSB antibody levels, reduce lymphocyte infiltration and acinus atrophy of submandibular glands and lacrimal glands, inhibit the expression of a cytokine INF-gamma, and the drug efficacy is equivalent to that of a positive medicine hydroxychloroquine; chrysin and gaoshunyujin have a synergistic effect, and the improvement effect on primary Sjogren's syndrome is better than that of hydroxychloroquine. The application provides a new medical use of chrysin, and provides a safe and effective prevention and treatment medicine for primary Sjogren's syndrome.
Owner:ZHEJIANG ACAD OF TRADITIONAL CHINESE MEDICINE

A low profile diplex filter antenna

PendingCN122158938Aachieve motivationSuppress cross polarizationRadiating elements structural formsAntenna earthingsDielectric substrateTransmission technology
The application provides a low-profile duplex filter antenna and belongs to the technical field of wireless energy transmission.The low-profile duplex filter antenna comprises an upper metal floor, a dielectric substrate, a lower metal floor, a cavity column, a perturbation via and a suppression via; the lower metal floor is arranged on the lower surface of the lower dielectric substrate; the upper metal floor is arranged on the upper surface of the dielectric substrate; the cavity column penetrates through the upper metal floor, the dielectric substrate and the lower metal floor and surrounds a substrate integrated waveguide cavity; the perturbation via and the suppression via penetrate through the upper metal floor, the dielectric substrate and the lower metal floor; a cross-shaped groove is etched in the center of the upper metal floor; two complementary split ring resonator grooves with different diameters are etched at the connection between the circular cavity and the two side rectangular cavities of the upper metal floor; two feed lines are led out from the two ends of the upper metal floor. The antenna has the characteristics of low profile, is easy to integrate, and simultaneously reduces the manufacturing cost of the antenna and facilitates processing and manufacturing.
Owner:CHONGQING COLLEGE OF ELECTRONICS ENG

A multi-beam simultaneously scannable active lens antenna system and design method

PendingCN122599719ANo mutual interferenceEliminate the sources of co-channel interference
This invention relates to the field of electromagnetic fields and microwave technology, specifically to a multi-beam simultaneously scannable active lens antenna system and its design method. The system includes several subsystems arranged in an array, each subsystem comprising a lens antenna assembly, a feed assembly, and a control module. The lens antenna assembly contains multiple reconfigurable metasurface arrays, composed of metasurface units with phase-modulating elements. The feed assembly is located within the focal length region and contains multiple antenna feeds. The control module is electrically connected to each phase-modulating element and outputs control signals. At least some adjacent antenna feeds within the same feed assembly operate at different frequencies, and the system is configured for simultaneous multi-beam operation, allowing feeds from different frequencies and different subsystems to operate simultaneously. This invention achieves simultaneous multi-beam scanning through the parallel operation of electronic phase modulation of the reconfigurable metasurface and different-frequency feeds, effectively improving spectrum utilization efficiency and eliminating co-frequency interference between beams.
Owner:XIDIAN UNIV HANGZHOU RES INST +1

Method for preparing tobacco flavor through polysaccharide Maillard reaction and application of tobacco flavor

The invention belongs to the technical field of tobacco flavor preparation, and discloses a method for preparing tobacco flavor based on polysaccharide Maillard reaction and application of the tobacco flavor. The method comprises the following steps: dissolving amino acid and polysaccharide in a solvent according to a certain molar ratio to obtain a reaction material; putting the reaction materials into a reaction kettle, and carrying out Maillard reaction under a closed condition; and after the reaction is finished, rapidly cooling the reaction kettle to room temperature to obtain a Maillard reaction product. In the reaction process, polysaccharide is cracked into various reducing sugars step by step and is subjected to Maillard reaction with amino acid, so that the problems that monosaccharide participates in the Maillard reaction, the aroma is single, and the reaction is violent and difficult to control are effectively solved. When the tobacco flavor is applied to cigarettes, the irritation of smoke can be remarkably reduced, offensive odor can be covered, meanwhile, the smoke is softened, the aftertaste is improved, the smoke concentration is increased, and the baking fragrance and the sweet aftertaste are increased. The method is low in cost, simple in equipment and convenient to operate, can be put into production without modifying existing production equipment, and has a good industrial application prospect.
Owner:ZHENGZHOU UNIVERSITY OF LIGHT INDUSTRY

Durable pet knot toy

ActiveCN224192695UDurabilityreliable materialTaming and training devicesYarnPolyester
The utility model relates to the technical field of pet toys, and discloses a durable pet knotting toy which comprises a rope body woven by polyester woven threads, two ends of the rope body are connected with rope balls woven by nylon woven threads in a #-shaped mode through woven ropes, vibration balls are arranged in the rope balls, and a motor provides power for a transmission system in the vibration balls. An output shaft drives one bevel gear and is meshed with the other two bevel gears, two eccentric wheels are driven by a connecting rod to rotate to generate vibration, attention of pets is attracted, dynamic interestingness of the toy is increased, meanwhile, a groove and a U-shaped fixing plate provide stable support for internal parts, friction of the eccentric wheels is reduced through an arc-shaped groove, durability of the toy is improved, and power is supplied through a battery. The charging port facilitates charging, the waterproof plug prevents water from damaging parts, stable operation of the toy is ensured, the service life is prolonged, and better interactive experience is brought to pets and owners.
Owner:CANGNAN COUNTY WANLI ROPE PROD CO LTD

Composite anchoring structure and anchoring method for wind power mixed tower

The invention discloses a composite anchoring structure and an anchoring method of a wind power mixed tower, the composite anchoring structure comprises a mixed tower body, the lower part of the mixed tower body is a concrete tower tube section, and the composite anchoring structure further comprises a concrete foundation buried under the earth surface and used for bearing the mixed tower body; the external pre-stressed anchoring assembly comprises a pre-stressed cable and an anchor base, the upper end of the pre-stressed cable is connected with the mixed tower body, the lower end of the pre-stressed cable extends to the outer side of the concrete foundation and is anchored to the upper portion of the outer side wall of the concrete foundation through the anchor base, and an anchoring point is higher than the ground surface; the built-in pre-stressed anchor bolt assembly comprises a pre-stressed anchor bolt, an upper anchor plate and a lower anchor plate, the upper anchor plate is pre-embedded in the top of the concrete foundation and fixedly connected with the bottom of the concrete tower drum section, the lower anchor plate is pre-embedded in the lower portion of the interior of the concrete foundation, the pre-stressed anchor bolt penetrates through the concrete foundation, and the two ends of the pre-stressed anchor bolt are fixedly connected with the upper anchor plate and the lower anchor plate correspondingly; prestress is applied to the concrete foundation, and the concrete tower drum section is anchored on the concrete foundation. The problems that a traditional anchoring structure is inconvenient to construct, difficult to overhaul and prone to cracking and water seepage are solved.
Owner:HUANENG ANDA CITY CLEAN ENERGY CO LTD +1

An acoustically powered thrombolytic system and its use

This invention discloses a sonodynamic synergistic thrombolysis system and its application. The system includes a tissue plasminogen activator variant, a sonosensitive agent, and an ultrasound source. The tissue plasminogen activator variant is an intravenously administered formulation, the sonosensitive agent is an intravenously infused formulation, and the ultrasound source is used to emit ultrasound during sonosensitive agent administration to activate the agent. This invention significantly improves thrombolysis efficiency and reduces thrombolytic agent dosage and bleeding risk through the dual synergistic effect of TNK-tPA enzymatic hydrolysis and sonodynamic chemical oxidation. The system can significantly improve vascular recanalization rate and blood flow velocity recovery rate, and has high biocompatibility. This invention is applicable to thrombolytic treatment of various thrombotic diseases and has the advantages of simple operation, strong targeting, and wide application range.
Owner:ARMY MEDICAL UNIV

A method and system for determining the minimum miscibility pressure of a tubular simulation considering nano-confinement effect

PendingCN122509063Aplay a regulatory roleImproved utilization efficiency
This invention relates to a method and system for determining the minimum miscibility pressure in capillary simulation considering the nanoconfining effect. The method includes: constructing a fluid thermodynamic model based on the nanoconfining effect; establishing a one-dimensional capillary simulation model integrating the nanoconfining effect; conducting a series of constant pressure displacement simulations considering the confinement effect; determining the minimum miscibility pressure under nanopores based on the inflection point method; modifying the fluid equation of state based on the nanoconfining effect, and substituting the modified equation of state into the one-dimensional capillary displacement model for numerical simulation to obtain the recovery response characteristics under different pressure sequences. The minimum miscibility pressure is accurately characterized by the inflection point method, and the influence of the nanoconfining effect on miscibility can be quantitatively evaluated.
Owner:YANGTZE UNIVERSITY

Vigour-nourishing wine and preparation process thereof

The invention discloses vigor-nourishing wine and a preparation process thereof, and relates to the technical field of health-preserving wine preparation processes, the vigor-nourishing wine comprises 10-30 parts of semen cuscutae, 10-25 parts of polygonum multiflorum, 10-25 parts of codonopsis pilosula, 10-25 parts of astragalus membranaceus, 8-20 parts of herba epimedii, 8-20 parts of radix puerariae, 5-15 parts of angelica sinensis, 5-15 parts of poria cocos, 5-15 parts of cassia twig, 5-15 parts of medlar, 5-15 parts of jujube and 5-15 parts of schisandra chinensis. Semen cuscutae and radix polygoni multiflori are used as monarch drugs to tonify kidney and replenish essence and consolidate basis; codonopsis pilosula and astragalus membranaceus are used as ministerial drugs to tonify qi and spleen and strengthen healthy energy and consolidate superficies; herba epimedii, radix puerariae, angelica sinensis and the like are used as assistants and guides for promoting blood circulation to remove meridian obstruction and regulating yin and yang The twelve medicinal materials have a synergistic effect and have the effects of tonifying primordial qi, regulating yin and yang and dredging meridians and collaterals.
Owner:赵俊

Egg white source active peptide as well as preparation method and anti-inflammatory application thereof

The invention belongs to the technical field of biology, and particularly relates to an egg white source active peptide, a preparation method of the egg white source active peptide and application of the egg white source active peptide to inflammation resistance, and the amino acid sequence of the egg white source active peptide is shown as any one of AMKRHGLDNYRGYS and AMKRHGLDNYRGYSLG. According to the method for preparing the egg white source active peptide with the anti-inflammatory activity by fermenting the egg white through the aspergillus oryzae, the two peptide fragments with the anti-inflammatory activity effect are screened through the method, and the peptide fragments can inhibit NO generation and albumin denaturation, have good anti-inflammatory activity and can be used for preparing the egg white source active peptide with the anti-inflammatory activity. The peptide can effectively improve the inflammatory bowel disease of a human body, can relieve acute colitis after being taken for a short time, has a good improvement effect on chronic colitis after being taken for a long time, and is easy in small molecule absorption, food-sourced, safe and low in sensitivity.
Owner:HAINAN UNIV

TRPM8 agonist and application thereof in preparation of medicine for preventing or treating TRPM8 related diseases

PendingCN121818651AHave agonistic activityquick effectOrganic active ingredientsSenses disorderDiseasePharmaceutical drug
The invention discloses an application of sotrasturin, or a stereoisomer of sotrasturin, or a raceme of sotrasturin, or a pharmaceutically acceptable salt of sotrasturin, or a solvate of sotrasturin in the development of a medicine for preventing or treating TRPM8 related diseases. Particularly, sotratolin is disclosed as a TRPM8 agonist, and a good prevention or treatment effect can be obtained when sotratolin is used for preventing or treating xerophthalmia; in a mouse xerophthalmia model induced by a benzalkonium chloride solution, sotratoline has a remarkable improvement effect.
Owner:CHINA PHARM UNIV

A method of making thompson seedless white wine by carbon dioxide infusion fermentation

The present application relates to the technical field of wine brewing, in particular to a method for brewing Thompson Seedless white grape wine by carbon dioxide impregnation fermentation, comprising the following steps: adopting a process scheme combining carbon dioxide whole fruit impregnation and sequential inoculation of multiple yeasts, placing whole Thompson Seedless white grape berries in a closed carbon dioxide environment for impregnation at 28-32 DEG C for 8-12 days to promote the dissolution and conversion of skin aroma precursors; after crushing, juice extraction and clarification, first inoculating non-wine yeast such as Cryptococcus or Saccharomycodes deemii for fermentation for 48 hours, and then inoculating wine yeast QA23 or EC1118 to complete main fermentation and segmented temperature control. The present application significantly increases the content of ester and terpene aroma substances, enhances fruitiness and floral characteristics, effectively improves the complexity and level of aroma, guarantees fermentation stability, and provides a new technical approach for the quality upgrading of Thompson Seedless white grape wine.
Owner:XINJIANG AGRI UNIV

Traditional Chinese medicine oral prescription for preventing and treating influenza A and improving digestive tract diseases

PendingCN121971580Aeffective preventioneffective therapeuticDispersion deliveryDigestive systemForsythiaWolfiporia extensa
The invention discloses a traditional Chinese medicine oral prescription for preventing and treating influenza A and improving digestive tract diseases, and belongs to the technical field of traditional Chinese medicines. The prescription is prepared from kudzuvine root, radix bupleuri, moutan bark, peach kernel, scutellaria baicalensis, raw rhubarb, pinellia ternate, fructus forsythiae, mirabilite, mangnolia officinalis, immature bitter orange, poria cocos, bighead atractylodes rhizome, rhizoma alismatis, white paeony root, Chinese date and ginger which are strictly matched according to a specific weight ratio and are prepared by a specific water decoction process. The traditional Chinese medicine oral prescription can effectively prevent and treat influenza A through the synergistic effect of the components, has a remarkable improvement effect on most of digestive tract diseases, is simple in preparation process, convenient to take and high in safety, avoids the problems of poor curative effect, obvious side effect or narrow application range and the like of related medicines in the prior art, and has a wide application prospect. And a new effective choice is provided for prevention and treatment of influenza A and improvement of digestive tract diseases.
Owner:郝华伟

A traditional Chinese medicine composition for treating generalized anxiety and a preparation method and use thereof

ActiveCN121371104BTreatment for Generalized Anxiety Disordersuitable for treatmentNervous disorderPlant ingredientsCurcuma aromaticaGeneralized anxiety
The present application provides a traditional Chinese medicine composition for treating generalized anxiety and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 8-17 parts of Cortex Albiziae, 15-30 parts of Triticum Aestivum, 6-14 parts of Radix Paeoniae Alba, 4-10 parts of Radix Bupleuri, 3-10 parts of Radix Curcumae, 4-10 parts of Radix Salviae Miltiorrhizae, 3-9 parts of Fructus Schisandrae Chinensis, 5-11 parts of Fructus Jujubae and 3-10 parts of Radix Glycyrrhizae. The components have a synergistic effect and can obviously improve mCPP-induced anxiety-like behavior of mice, mCPP-induced anxiety-like behavior of rats, chronic restraint stress-induced anxiety-like behavior of mice and PCPA-induced anxiety-like behavior of rats. The traditional Chinese medicine composition has excellent effects of improving generalized anxiety and can be applied to the preparation of drugs for improving generalized anxiety.
Owner:NINGBO JIURUI PHARMACEUTICAL CO LTD

Application of birch juice separation liquid in improvement of parenchymal hepatic cell injury

The invention belongs to the field of medical application of birch juice, and discloses application of a birch juice separating medium to improvement of parenchymal hepatic cell injury, the birch juice separating medium is used for improving parenchymal hepatic cell injury, and the birch juice separating medium is prepared according to the following steps: S1, raw material pretreatment; s2, preliminary filtration; s3, performing ultrafiltration; s4, performing nanofiltration concentration; s5, chromatographic purification; s6, vacuum drying; according to the technical scheme, the birch juice separation liquid is applied to improvement of the parenchymal hepatic cell injury, the parenchymal hepatic cell injury is improved through the birch juice separation liquid, the application field of the birch juice is expanded, and experiments show that the birch juice separation liquid prepared through the technical scheme can remarkably reduce transaminase release of the injured parenchymal hepatic cells, so that the survival rate of the injured parenchymal hepatic cells is increased. The traditional Chinese medicine composition has the advantages that the activity of antioxidant enzymes is improved, the content of lipid peroxidation products is reduced, and the traditional Chinese medicine composition has a good improvement effect on parenchymal hepatic cell injury induced by various factors and provides a new natural active substance source for preventing and treating liver injury.
Owner:YICHUN ZHAOTIAN BIOTECHNOLOGY CO LTD

Genome scale metabolic network model deletion reaction prediction and filling method and system

PendingCN122090962AFully capture dynamic charactersFully capture interactionsBiostatisticsBiological modelsMetaboliteData set
The invention discloses a genome scale metabolic network model deletion reaction prediction and filling method and system, and the method comprises the steps: obtaining a plurality of genome scale metabolic network models from a metabolic network database, and constructing a data set with a supervision label; extracting and fusing the molecular sequence and molecular map characteristics of the metabolite to obtain an initial characteristic vector; constructing a metabolic directed graph and a metabolic reaction hypergraph based on a positive reaction sample, performing feature directivity enhancement by using the directed graph, and extracting high-order topological information through a hypergraph convolutional neural network to obtain final feature representation of metabolites; on the basis of the feature representation, adopting an attention mechanism to predict candidate reaction confidence and training a model; and finally, screening a high-confidence reaction from the candidate reaction pool and filling the target model with the high-confidence reaction. According to the method, the metabolite multi-dimensional molecular characteristics and the network high-order topological information are deeply fused, the prediction accuracy is remarkably improved, the method does not depend on experimental data, and the method is suitable for efficient metabolic network model correction and optimization.
Owner:JIANGNAN UNIV

A curriculum learning method for neural machine translation field adaptation

PendingCN122509209Afast convergenceAlleviate the fitting problem
The application discloses a kind of neural machine translation field adaptive course learning method, belong to natural language processing technical field.The application is directed to the problems of big difference in field, low-resource field data scarcity, traditional fine-tuning easy overfitting and data difficulty static evaluation in neural machine translation, and proposes a domain adaptation scheme based on progressive curriculum learning.Adopting the progressive training strategy from easy to difficult, first introduce general easy learning samples, gradually increase the high-difficulty samples of target field;Fusion transfer learning, adversarial training and multi-task learning optimize model generalization ability, dynamically match model capability and sample difficulty.Experiments show that, in the multilingual pairs such as English-German, Chinese-English and low-resource field translation, the BLEU value is significantly improved, the noise resistance and robustness are stronger, effectively alleviate the field distribution mismatch and overfitting problem, improve the cross-domain adaptation efficiency of model, suitable for medical, legal and other professional field machine translation scene.
Owner:DALIAN UNIV OF TECH

Lightweight automobile bumper based on long fiber reinforced composite material and preparation process of lightweight automobile bumper

PendingCN121973468ACounteract stress concentrationsSolve the problem of failureDomestic articlesBulk chemical productionMechanical integrityPlasticizer
The invention discloses a lightweight automobile bumper based on a long fiber reinforced composite material and a preparation process thereof, and the preparation process comprises the following steps: mixing an energy-absorbing fluid and a mesoporous carrier, carrying out vacuum impregnation, and sucking the energy-absorbing fluid into the mesoporous carrier to prepare a filler without a free liquid state; the method comprises the following steps: dipping continuous fibers in resin, directionally laying the continuous fibers in a hot-pressing mold of an automobile bumper, and adding long fibers for filling and a thermoplastic polymer matrix mixed with a filler; the method comprises the following steps: injecting a supercritical fluid plasticizer into a molten polymer matrix in a mold cavity in a pressurizing and heating environment, infiltrating the plasticizer among polymer molecular chains to increase free volume, and infiltrating and calendering the continuous fibers, the long fibers and the filler by the matrix in a low-temperature environment; and releasing pressure, demolding, cooling and shaping to obtain the lightweight bumper. And the mechanical integrity of the anti-collision structure under the extremely high-speed collision working condition is further ensured.
Owner:JIANGSU KEXIN AUTOMOBILE DECORATION PARTS

Guide conveying device for film blowing machine products

The utility model discloses a guiding and conveying device for a film blowing machine product. Belongs to the technical field of plastic film production equipment. According to the technical key points, the device comprises a supporting frame, a film blowing machine is arranged at the bottom of the supporting frame, and a die head is arranged at the top of the film blowing machine; the rotating plates, the connecting plates, the notches, the connecting rods, the driving mechanism and the limiting guide rods are used in cooperation, when a plastic film product is limited and guided, the driving mechanism drives one of the connecting plates and the rotating plates to rotate, all the rotating plates can rotate synchronously under cooperation of the connecting rods, and therefore the plastic film product is limited and guided. The limiting guide rods are driven to rotate synchronously, so that the limiting guide rods can be attached to the outer wall of the plastic film product at the same time, the plastic film product is guided and limited, the operation process is simple and convenient, and meanwhile the limiting guide rods can be attached to the outer wall of the plastic film product at the same time rapidly; and the upward conveying stability of the plastic bag products is ensured.
Owner:MIANYANG YONGJU NEW ENERGY TECHNOLOGY CO LTD