The invention relates to a highly selective oxygen-containing coal mine methane catalytic deoxidation catalyst and a preparation method thereof. One of or a combination of several of the noble metal Pt, Pd and Rh is adopted as the main active component, rare earth, alkaline earth or alkaline metal is taken as the additive, and one or more of ZrO2, TiO2, Co3O4, SnO2, CuO, Fe2O3, CeO2, and SiO2 are adopted as the carrier. The catalyst carrier can be molded through different methods, and then the additive and the active component are employed to coat the molded carrier, or the carrier, the additive and the active component are employed to coat (wall load) the whole structure catalyst or metallic honeycomb for application. The catalyst provided by the invention has the characteristics of complete combustion activity of methane and selectivity under high fuel-rich atmosphere, no H2 or CO in the product, and the like. The catalyst can be applied to catalytic deoxidation of oxygen-containing coal mine methane, and also can be used for other combustible gas removal processes to realize new energy development and energy saving and emission reduction.