The invention relates to a wet process vanadium extraction technology of clay ore, providing a valuable metal technology for extracting vanadium by wet process from vanadium clay ore, which belongs to the non-ferrous metal metallurgical technology field. The invention is characterized in that disintegrating clay ore, proceeding thermostatic mixing acid leaching reaction as adding sulfuric acid, fluohydric acid and oxidation agent under certain liquid solid volumetric ratio, separating solid and liquid, removing out iron and aluminum and recycling to utilize after leaching solution being treated by multistep pH value regulation and alkali deposition solubilization reaction, depositing vanadium by ammonium salt after purified vanadium being regulated pH value, filtering, drying and calcining ammonium metavanadate which is prepared to obtain vanadium pentoxide powder. The invention directly leaches clay ore mixing with acid, has high acid leaching rate, lower energy consumption, short technical process, easy operation and control, low productive cost, environment-friendly and safety, realizes zero discharge in the production process, has no waste gas generation, and recycles waste water and valuable metal, and the recycle rate of vanadium reaches 70-75%, purity of vanadium pentoxide of the product is larger than 99%.