41 results about "Sodium iodide" patented technology

The invention discloses a method for preparing 2, 5-diformyl furan by selectively oxidizing 5-hydroxymethylfurfural, which comprises the following steps of: reacting 5-hydroxymethylfurfural serving as a raw material, air or oxygen serving as an oxidant, nitrate or ferric salt and sodium iodide serving as main active components of a catalyst and DMSO (dimethylsulfoxide) serving as a solvent at the temperature of between 80 and 160 DEG C for a certain time under the condition of normal pressure, and separating a product to obtain the 2, 5-diformyl furan. The ferric salt is ferric nitrate nonahydrate, and the catalyst is 2, 5-diformyl furan. The dosage of the ferric salt is 0 to 0.50 mmol; the use amount of the sodium iodide is 0 to 0.50 mmol. According to the method, DMSO is adopted as a solvent, the used catalyst is cheap and easy to obtain, the yield of 2, 5-diformyl furan can reach 95% at most after the reaction is carried out at 140 DEG C for 20 h, the requirement for equipment is low, and the method is suitable for industrial production.

The invention belongs to the field of chemical reagents, and particularly relates to a preparation method of alcohol-free acetone. The preparation method comprises the following steps: S1, carrying out primary adsorption by using a 4A molecular sieve and a 5A molecular sieve; s2, carrying out secondary adsorption by using a 4A molecular sieve, a 5A molecular sieve and a 10X molecular sieve; s3, adding sodium iodide into the acetone solution subjected to secondary adsorption treatment according to a solid-to-liquid ratio of 1: 4; s4, washing the crystal with absolute ether at least twice, then carrying out solid-liquid separation, and heating and distilling at 80-100 DEG C; s5, repeating S3 and S4, and carrying out secondary crystallization and crystal cleaning; s6, carrying out dehydration treatment on a crude product subjected to secondary distillation by using a 3A molecular sieve; and S7, carrying out rectification on the dehydrated crude product alcohol-free acetone in a temperature range of 80-100 DEG C. According to the technical scheme, before sodium iodide is added for adduct crystallization and purification, a step-by-step molecular sieve adsorption pretreatment process is introduced. According to the process, two molecular sieves with matched pore diameters and polarities are adopted, an industrial-grade acetone raw material is sequentially subjected to two times of adsorption treatment, and the purpose of synergistic purification is achieved by targeting different impurities.

The invention relates to the field of organic synthesis, in particular to a synthetic method of (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate. The synthesis method of (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate comprises the following steps: mixing a material A, a material B, potassium carbonate, sodium iodide and a solvent, and reacting to obtain a material C; mixing the material C, the material D, triethylamine and a solvent, and reacting to obtain a material E; mixing the material E, ammonia water and a solvent, and reacting to obtain a material F; and mixing the material F, di-tert-butyl dicarbonate, a palladium carbon catalyst and a solvent, and carrying out a reaction to obtain the (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate. The process route is easy to operate and has no special dangerous reaction. Reaction materials are cheap and easy to obtain, and the prepared product is high in purity.

The application discloses a preparation and purification method of high-purity radioiodine-labeled antigen. The method comprises the following steps: pre-activating carrier-free sodium iodine[125I] solution in an orthogonal solvation sensitization buffer containing lithium sulfate, 18-crown-6 and beta-cyclodextrin; adding antigen and chloramine-T for a labeling reaction; and performing magnetic separation and purification by using a suspension containing adamantane-modified magnetic microspheres and quaternary ammonium salt-modified strong anion exchange magnetic microspheres after the reaction. The orthogonal solvation effect is used to enhance the nucleophilic activity of iodine ions, and the amount of oxidizing agent is reduced to reduce protein damage; impurities are quickly removed through the double mechanisms of electrostatic adsorption and host-guest recognition. The application has the advantages of high labeling efficiency, high radiochemical purity of the product and complete retention of biological activity.

The invention discloses a preparation method of L-2, 4-diaminobutyric acid dihydrochloride, which comprises the following steps: (1) taking L-homoserine as an initial raw material, and reacting with concentrated hydrochloric acid in the presence of a zinc chloride / ferrous chloride synergistic catalyst to prepare L-2-amino-4-chlorobutyric acid hydrochloride; (2) after neutralization, carrying out an acylation reaction with ethyl chloroformate to generate N-ethoxycarbonyl-L-4-chlorobutyric acid; (3) carrying out esterification with ethanol so as to obtain N-ethoxycarbonyl-L-4-chlorobutyl amino acid ethyl ester; (4) under the catalysis of sodium iodide, carrying out nucleophilic substitution reaction with phthalimide potassium salt, and cooling, crystallizing and purifying the key intermediate by dropwise adding water to obtain L-2-[(ethoxycarbonyl) amino]-4-phthalimide ethyl butyrate; and (5) finally, hydrolyzing for deprotection, and concentrating and crystallizing to obtain the L-2, 4-diaminobutyric acid dihydrochloride. The method has the advantages of mild reaction conditions, simplicity and convenience in operation, high total yield and the like, and is suitable for large-scale industrial production.

The invention belongs to the field of drug synthesis, and particularly relates to a preparation method of sodium 2, 3-dimercaptopropanesulfonate, which comprises the following steps: cooling a sodium hydroxide solution, reacting with thioacetic acid, adding 2, 3-dibromopropanesulfonic acid and sodium iodide, and heating to react to obtain a 2, 3-bis (acetylthio) propanesulfonic acid solution; the preparation method comprises the following steps: heating a 2, 3-bis (acetylthio) propanesulfonic acid solution and dilute sulphuric acid to react to obtain a 2, 3-dimercaptopropanesulfonic acid solution; the preparation method comprises the following steps: adding sodium acetate into a 2, 3-dimercaptopropanesulfonic acid solution to react to obtain a 2, 3-sodium dimercaptopropanesulfonate crude product, and refining to obtain a 2, 3-sodium dimercaptopropanesulfonate finished product. By optimizing the molar ratio of 2, 3-dibromopropanesulfonic acid, thioacetic acid, sodium hydroxide and sodium iodide, the reaction temperature, the solvent volume, the refining temperature, the refining solvent volume and other parameters, the purity of 2, 3-sodium dimercaptopropanesulfonate reaches 99.4%, and the yield reaches 54.5%. Sodium iodide is added as a catalyst to effectively improve the reaction efficiency and the product purity. The reaction does not need to adopt one-class metal lead, and the pollution is small.

The application provides a bromine-based leaching reagent system and a method for recycling precious metals from waste circuit boards, and belongs to the technical field of hydrometallurgy. The application takes stable bromine-based strong oxidant, sodium bromide and sodium iodide as the leaching reagent system, controls the bromine volatilization loss to be below 5% through the slow-release bromine mechanism, reduces the bromine consumption by more than 15% compared with the traditional liquid bromine leaching process, simultaneously introduces sodium iodide as a catalytic additive, and significantly reduces the sodium bromide consumption. The weak acid leaching environment is adopted, the leaching efficiency is ensured, and the equipment corrosion problem is effectively reduced. The developed "distillation-precipitation" coupling process realizes efficient recovery of silver and synchronous regeneration of bromine reagent, so that the bromine recycling rate is more than 80%. Through the construction of a gold selective reduction-silver distillation precipitation-palladium solvent extraction hierarchical separation system, efficient recovery of precious metals is realized. The application greatly reduces the processing cost through the recycling of bromine reagent, has significant industrial application value and broad market prospect.

This invention discloses an organic trace element complex for lactating dairy cows, comprising the following components in parts by weight: 40-70 parts of hydroxymethionine complex, 0.1-0.2 parts of sodium iodide, 30-45 parts of yeast selenium, 0.1-0.2 parts of cobalt sulfate, 10-25 parts of synergist, and 5-10 parts of carrier. This invention also discloses the preparation method and application of the above-mentioned organic trace element complex. When used in lactating dairy cows, the various hydroxymethionine complexes can effectively pass through the rumen to the small intestine and be absorbed through amino acid channels, meeting the needs of dairy cows for various trace elements during lactation. The synergistic effect of the various hydroxymethionine complexes and the synergist can improve the lactation performance of dairy cows, increase milk production, enhance the body's resistance, significantly reduce the incidence of mastitis and hoof diseases, and alleviate ketosis.

The application belongs to the technical field of organic synthesis, and particularly relates to a method for synthesizing 1-(2,4-dimethylphenyl)thio-N-benzyl-2-naphthylamine by a continuous flow light-heat integrated method. The method is performed in a micro-channel reaction device provided with light and heat. N-benzyl-2-naphthylamine, 2,2',4,4'-tetramethyl diphenyl disulfide and a catalyst sodium iodide are dissolved in acetonitrile solvent to obtain a reaction solution. A blue light is used as a light source of a reaction module, and the temperature is adjusted to 25-60 DEG C. Air or oxygen is introduced into the reaction solution, and magnetic stirring is performed. Then, the gas-liquid mixed reaction solution is input into the reaction module through a peristaltic pump to obtain 1-(2,4-dimethylphenyl)thio-N-benzyl-2-naphthylamine. The application creatively uses the continuous flow light-heat integrated reaction technology to synthesize 1-(2,4-dimethylphenyl)thio-N-benzyl-2-naphthylamine, greatly improves the reaction efficiency, shortens the reaction time, improves the safety and controllability of the reaction, solves the amplification effect of the conventional reaction, and provides a reaction technology without bottleneck amplification for the synthesis of the compound.

The invention discloses an efficient preparation method of mivacurium chloride, which comprises the following steps: (1) reacting (E)-octyl-4-ene-1, 8-diacid, 3-chloro-1-bromopropane, alkali, cesium chloride and a reaction solvent at the temperature of 30-100 DEG C for 6-15 hours; cooling after the reaction is completed, adding water and an organic solvent for extraction, and separating liquid; washing an organic phase with water, and concentrating under reduced pressure to obtain (E)-octyl-4-ene-1, 8-diacid di-(3-chloropropyl) ester; and (2) carrying out a reaction on the (E)-octyl-4-ene-1, 8-diacid di-(3-chloropropyl) ester, the (R)-(+)-5 '-methoxylaudanin, sodium iodide, potassium carbonate and the reaction solvent at the temperature of 50-85 DEG C for 18-40 hours, and carrying out post-treatment to obtain mivacurium chloride. The method disclosed by the invention is novel, avoids the use of thionyl chloride and a condensing agent, is more environment-friendly, is friendly to the environment and an operator, and is mild in reaction condition, high in reaction efficiency, high in yield, low in equipment requirement and simple to operate; the method has the advantages of cheap and easily available reaction raw materials and reagents, few by-products, simple purification and easy operation, and is suitable for preparation of human bulk drugs with high purity and safety requirements, and the purity of the obtained mivacurium chloride is higher than 99.5%.

This invention belongs to the field of experimental technology for oil and gas field development, specifically relating to an experimental device and method for CO2 injection at the gas-water interface to suppress bottom water displacement of natural gas. The device includes a reservoir simulation system, a fluid injection system, a multi-dimensional visualization monitoring system, and a production metering system. The reservoir simulation system uses a sand-filled pipe to simulate a vertical reservoir, and a temperature control module regulates the temperature of the sand-filled pipe. The fluid injection system uses a fixed-point injection pipe with adjustable depth that can penetrate deep into the pipe body to precisely inject CO2 into the gas-water interface. The multi-dimensional visualization monitoring system uses a scanner and krypton tracers mixed with simulated natural gas and sodium iodide tracers mixed with simulated formation water to achieve dynamic monitoring of multiphase fluids throughout the displacement process. This invention can simulate the vertical development characteristics of deep bottom water gas reservoirs with high fidelity, intuitively revealing the mechanism of CO2 inhibition of bottom water coning, and providing precise experimental basis for optimizing gas reservoir development schemes.

This application discloses a method for curing silver iodide, a ceramic curing body, and its applications. The method for curing silver iodide provided in this application, considering the widespread use of silver iodide in the treatment of radioactive iodine, directly uses silver iodide as a raw material, mixes it with barium source salt and sodium iodide salt raw materials, and prepares a ceramic curing body through steps such as dry pressing, reaction, and sintering, thereby curing radioactive iodine within the ceramic curing body. This method is simple, low-cost, and highly applicable, and can cure silver iodide with a content of 4.44–35.40 wt%. Compared with traditional iodine curing methods, it is more practical and can be applied to the disposal of radioactive iodine waste.

The utility model discloses a kind of sodium iodide crystal growth crucible with impurity filtering function, it is related to sodium iodide crystal manufacturing technical field, including crucible body, the upper side of the crucible body is fixedly connected with pot cover, the upper side of the pot cover is fixedly connected with the support frame of two left and right distribution, the upper side of the pot cover is fixedly connected with stirring mechanism, the lower side of the crucible body is overlapped with pouring mechanism, the inside of the crucible body is movably sleeved with graphite paper cylinder body.The utility model discloses a kind of sodium iodide crystal growth crucible with impurity filtering function, by motor drives rotating rod rotation, so that storage box is agitated to liquid, first telescopic rod drives storage box to move up and down, so that storage box is not in liquid when sodium iodide crystallization, reduce the adhesion of sodium iodide crystal, possibly rely on storage box and collect impurity, further improve the quality of sodium iodide crystal growth.

This invention relates to the field of organic synthesis technology, and in particular to a method for synthesizing alkynyl compounds based on mechanical ball milling. An ether compound is mixed with a compound of formula V, sodium iodide, and ethyl acetate, and then subjected to a ball milling reaction to obtain the alkynyl compound. The ball milling reaction conditions include a vibration frequency of 30 Hz and a vibration time of 30 min. This invention provides the first method to apply a mechanical strategy to the generation of alkynyl free radicals and the subsequent selenization reaction. Through ball milling-induced σ-hole sulfur bond SET, alkynyl sulfonium salts generate alkynyl free radicals and synthesize alkynyl selenides. Compared with existing technologies, the method for generating alkynyl free radicals described in this invention does not require metal catalysts or ultraviolet excitation, achieves high yields of alkynyl selenides, and features simple operation and mild reaction conditions.

The application discloses isoquinoline sulfone compounds, a preparation method and application thereof. Isoquinoline N-O compounds and sodium benzenesulfinate compounds are used as reactants, a carbon rod is used as a positive electrode, a platinum sheet is used as a negative electrode, sodium iodide is used as an electrolyte, and a mixed solution of acetonitrile, water and acetic acid is used as a reaction liquid, under the conditions that the current is 12 mA, the temperature is 35 DEG C, and after 6 hours of reaction, a series of isoquinoline sulfone compounds can be obtained. The isoquinoline sulfone compounds have potential application to the development of new herbicides.

The invention discloses an in-situ online monitoring method and system for radioactive substances in nuclear medicine waste liquid, and the method comprises the steps: directly placing a detector in decay pool radioactive waste liquid, transmitting an electrical signal to a data terminal through a signal line, and connecting an online monitoring data management platform through a 5G mobile communication network; a sodium iodide detector is selected, and the radioactive activity of iodine 131 is monitored by adopting an energy spectrum analysis method; the total alpha and total beta radioactivity is converted by measuring gamma ray activity accompanied by characteristic nuclide decay. The system comprises a detector, a data terminal, a 5G mobile communication network and an online monitoring data management platform. According to the invention, through in-situ monitoring and energy spectrum measurement, the monitoring analysis time is shortened, and the problem that direct measurement is difficult due to short range of alpha and beta rays in water is solved.

The invention belongs to the field of preparation and application of nano materials, and discloses a simple method for preparing small-size silver halide (AgX: X = Cl, Br and I) nano particles. The preparation method comprises the following steps: respectively dropwise adding an ethylene glycol solution of silver nitrate and an ethylene glycol solution of sodium iodide into a stirred oleylamine phase; the small-size silver iodide nanoparticles are prepared by a method for controlling precipitation of silver ions and iodide ions in an oleylamine phase. The method has the main advantages that (1) the process is simple, the operation is convenient, and only three steps of solution preparation, stirring control and centrifugal separation are needed; and (2) the preparation process has good repeatability and controllability, and the average size of the synthesized nanoparticles can be controlled within 10nm. And (3) the prepared silver iodide nanoparticles have the characteristics of large specific surface area, high active sites and the like, and are suitable for preparing photocatalysts, artificial rainfall agents, CT contrast agents and the like.

The invention discloses a method for determining the residual DNA content of HEK293 host cells. The method comprises the following steps: preparing a sample to be detected and a series of standard substances; dNA (deoxyribonucleic acid) extraction: adding a standard substance or a sample into a deep-well plate, sequentially adding BSA (bovine serum albumin) and the enzymolysis mixed solution for incubation, adding the extraction mixed solution for conjugation reaction, centrifuging, and discarding supernatant to obtain extracted DNA; qPCR (quantitative polymerase chain reaction) detection: primer probe sequences for qPCR detection are shown as SEQ ID NO: 1-3. According to the method provided by the invention, the residual DNA is efficiently extracted through sodium iodide, the specific primer probe and qPCR are combined, quantitative detection is realized, the limit of quantitation is 10 pg / ml, and the sensitivity is high; meanwhile, a 96-well plate is adopted for sample treatment and PCR reaction, the detection flux is improved, the detection cost is reduced, and the kit is clear in formula, good in stability and capable of meeting the high-sensitivity and high-flux detection requirements of the residual DNA of the HEK293 host cells.

The invention provides a preparation method of an SERS (Surface Enhanced Raman Scattering) substrate based on a gold-silver polyhedron alloy nano frame. The preparation method comprises the following steps: preparing gold polyhedrons with different sizes through a'three-step 'seed growth method; sequentially adding chloroplatinic acid and chloroauric acid to react to form a hollow platinum framework; further adding chloroplatinic acid, silver nitrate and ascorbic acid to prepare a hollow gold-platinum polyhedral nano material; treating by sodium iodide and chloroplatinic acid to obtain a platinum-gold-platinum alloyed nano material, and removing internal gold by using chloroauric acid to form a new platinum framework; selectively depositing gold or silver on the surface to obtain a platinum-gold or platinum-silver alloyed nano material; the gold and silver alloyed nano-frame material is prepared by mixing the gold and silver alloyed nano-frame material and is applied to detection of nitrophenol. The alloy nano-frame can significantly improve the sensitivity and stability of p-nitrophenol detection, and has a good application prospect.

The invention relates to the technical field of shale, in particular to a nano tracer agent and a shale matrix pore water content calculation method, and the nano tracer agent comprises hexamethyl phosphonite triamide (HMPT) (boiling point is 233 DEG C), n-decane (C10H22) (boiling point is 233 DEG C) and radioactive reagent sodium iodide. Through a tracer experiment, the water content in the pores of the shale matrix can be calculated by utilizing the tracer concentrations of different pores, and the problem of water content calculation is solved from the microscopic distribution level.

The application discloses a hole transport material based on a carbazole derivative containing a benzene sulfonic acid unit and a preparation method and application thereof, relates to the technical field of solar cells, and a structural formula of the hole transport material is shown as formula I: in the formula, R1 is selected from H, C 1‑6 alkyl, C 1‑6 alkoxy or C1-6 alkylthio; R2 is selected from H, C 1‑6 alkyl, C 1‑6 alkoxy or C1-6 alkylthio. The technical scheme of the application takes 4-bromobenzenesulfonyl chloride as an initial raw material, carries out a substitution reaction with neopentyl alcohol to obtain a corresponding benzene sulfonate, carries out a coupling reaction with carbazole to obtain a carbazole sulfonate, finally carries out a reaction with sodium iodide to obtain an intermediate compound B3, and then carries out a reaction with hydrochloric acid in an ethanol solvent to obtain a final compound. The reaction process is simple, is not dangerous, has a short reaction time, has few side reactions, has a high reaction yield, and has the advantages of high purity of a reaction product and the like.

The invention belongs to the technical field of capacitors, and discloses a high-voltage fast-charging hybrid supercapacitor and a preparation method and application thereof. The hybrid supercapacitor comprises a positive electrode, a negative electrode, a diaphragm and an electrolyte, the positive electrode comprises a positive current collector and a positive active layer combined on the surface of the positive current collector, and the negative electrode comprises a negative current collector and a negative active layer combined on the surface of the negative current collector; the electrolyte comprises a molecular catalyst and a fluorine-containing organic solvent; the molecular catalyst comprises one or more of sodium iodide, sodium chloride, magnesium chloride, cobalt chloride, ammonium chloride, ammonium iodide, cobalt bromide, sodium bromide, aluminum bromide, lithium bromide, lithium iodide, zinc chloride and zinc iodide; the fluorine-containing organic solvent comprises a fluoro-carbonic ester organic solvent and / or a fluoro-ether organic solvent. The hybrid supercapacitor provided by the invention has the advantages of rapid charging and discharging capability, high working voltage, high energy density, high power density and excellent cycle life, and is suitable for higher energy storage and release requirements.

The invention discloses a preparation method of a fluorescent dye crude product, which is characterized by comprising the following steps: adding 1, 1, 2-trimethyl-3-(4-sulfonic acid butyl)-1H-benzo [e] indole inner salt and 2-[6-(acetanilino)-1, 3, 5-hexantrienyl]-1, 1-dimethyl-3-sulfonic acid butyl-1H-benzo [e] indole inner salt into absolute ethyl alcohol, dropwise adding triethylamine, reacting for 4-5 hours, filtering, washing, and drying to obtain the fluorescent dye crude product, namely the 2-[6-(acetanilino)-1, 3, 5-hexantrienyl]-1, 1-dimethyl-3-sulfonic acid butyl-1H-benzo [e] indole. Dropwise adding an absolute ethyl alcohol solution of sodium iodide, after dropwise adding, adding purified water, heating and stirring to completely dissolve the solid, and then cooling and crystallizing to obtain a fluorescent dye crude product; meanwhile, the invention discloses a refining method of the fluorescent dye crude product. And the yield of the fluorescent dye is ensured, and impurities and solvent residues meet the limit.

The invention relates to a calcium iodide-based organic electrolyte, a secondary battery and a preparation method of the calcium iodide-based organic electrolyte, the electrolyte is composed of calcium salt, an organic solvent and an additive, the calcium salt is calcium iodide or a combination of calcium iodide and other calcium salt, the organic solvent is one or a combination of more of ether organic solvent, sulfone organic solvent, ester organic solvent, amide organic solvent, ionic liquid organic solvent and amine organic solvent; the additive is selected from one or more of lithium borohydride, sodium borohydride, potassium borohydride, zinc borohydride, magnesium borohydride, lithium iodide, sodium iodide, magnesium iodide, potassium iodide, tetraethyl ammonium borohydride, tetramethyl ammonium borohydride, benzyltriethyl ammonium borohydride and tetra-n-butylammonium borohydride. Compared with the prior art, the fluoride-free, thermodynamically stable and low-passivation-effect calcium iodide-based electrolyte provided by the invention can improve the interface property of a calcium metal negative electrode-electrolyte and increase the stability of the electrolyte, so that the cycle life of a calcium metal battery is prolonged, and the stability of the calcium metal battery is improved.

This invention relates to the field of analytical detection technology, and more particularly to an iodine [ 131 [I] A method for determining the radioactive purity and iodide content in sodium iodide capsules. The method of this invention includes: determination using high-performance liquid chromatography (HPLC), wherein the mobile phase consists of mobile phase A and mobile phase B, wherein mobile phase A is a mixed solution of tetrabutylammonium hydrogen sulfate and disodium hydrogen phosphate, and mobile phase B is acetonitrile. This invention's detection method can rapidly determine the radioactive purity and iodide content of therapeutic iodine [I]. 131 The method for determining the radiochemical purity and iodide content in sodium iodide capsules is fast and possesses excellent specificity, accuracy, stability, robustness, and reliability. It is well-suited for the determination and control of radiochemical purity and iodide content. Furthermore, the establishment of this analytical method enables the determination of radiochemical purity and iodide content in therapeutic iodine capsules. 131 The accurate detection of radiochemical purity and iodide content in sodium chloride capsules has played an important guiding role in the development and optimization of formulation processes.

The invention provides a preparation method of an alkyl alcohol amine compound, which comprises the following steps: (1) mixing an alcohol compound with sodium iodide and zirconium chloride in a solvent, and reacting under a heating condition to obtain a reaction mixture containing an intermediate; and (2) mixing the reaction mixture with diethanol amine and an alkaline reagent, reacting under a heating condition, and purifying the obtained product to obtain the alkyl alcohol amine compound. According to the preparation method of the alkyl alcohol amine compound, the alcohol compound which is low in price and easy to obtain is adopted as the starting raw material, so that the raw material cost is remarkably reduced, and the economical efficiency of the synthesis process is improved. More importantly, a catalytic system consisting of zirconium chloride and sodium iodide is adopted to jointly act on the alcohol compound, so that efficient and high-selectivity iodination reaction is realized. The method has the advantages of mild reaction conditions, simple operation, simplified work flow, low toxicity and easy acquisition of raw materials, and easy purification of reaction products.

This invention relates to the field of biofunctional materials, and discloses a method for preparing and applying a near-infrared II photoresponsive Bi / BiOI enhanced composite enzyme. Specifically, the method involves first preparing BiOI nanomaterials by heating a reaction mixture of bismuth pentahydrate as the bismuth source, sodium iodide as the iodine source, and ethylene glycol as the reaction solvent for a period of time; then, the Bi / BiOI composite enzyme is obtained by reduction with sodium borohydride. This composite enzyme exhibits good crystallinity, with a spherical morphology of 500-700 nm, and possesses CAT enzyme activity under tumor microenvironment response. Simultaneously, it displays excellent self-enhancing enzyme activity under near-infrared II light, effectively solving the low activity problem commonly found in current cancer therapy nanozymes, and also showing potential application in CT imaging.

The application discloses a purification method for producing iodine-131 by a reactor with a uranyl nitrate solution as nuclear fuel, and comprises the following steps: adding a reducing agent into a crude iodine-131 product solution to reduce sodium iodine-131 into iodine-131 element; distilling the iodine-131 element to obtain iodine-131 element vapor; and absorbing the iodine-131 element vapor by using an alkaline solution to obtain a sodium iodine-131 solution product. The purification method can effectively remove radioactive impurities in the iodine-131 extracted from the reactor with the uranyl nitrate solution as the nuclear fuel, and can obtain the sodium iodine-131 solution product meeting the medical requirements. The purification method for the iodine-131 isotope is simple, and can effectively remove the impurities in the iodine-131 isotope, so that the iodine-131 isotope meets the medical requirements, and the average recovery rate of iodine can reach more than 90%.

The invention belongs to the field of organic synthesis, and particularly relates to a cyano enaminone compound and a preparation method thereof. The preparation method of the compound comprises the following steps: taking non-activated fatty amine and beta-ketonitrile as raw materials, adding an organic selenium catalyst, taking acetonitrile as a solvent, taking sodium iodide as an electrolyte, and taking graphite rods as an anode and a cathode respectively, introducing current, stirring and reacting at room temperature, thereby obtaining the cyano enaminone target compound. According to the technical scheme, a new thought is provided for widening the chemical structure and synthesis methodology of the cyano enaminone compound.

The invention relates to a method for collecting micro-particles on an asphalt pavement and analyzing physicochemical properties of the micro-particles, belongs to the technical field of road traffic environments, and solves the problems of low collection efficiency of the micro-particles on the asphalt pavement, incomplete analysis method and insufficient analysis and research on the micro-particles in the prior art. According to the method, firstly, vacuum dust collection and brushing and sweeping collaborative sampling are carried out, after screening and digestion pretreatment, a sodium iodide solution with the density of 1.8 g / cm < 3 > is adopted for density separation and centrifugation, and efficient enrichment of asphalt microparticles and tire abrasion microparticles is achieved. And then systematically analyzing the physicochemical properties and relative contents of the two types of microparticles by comprehensively utilizing various technologies such as a thermal cracking-gas chromatograph-mass spectrometer, a stereoscopic microscope, image analysis, a microscopic infrared spectrum, a scanning electron microscope-energy spectrometer and an inductively coupled plasma mass spectrometry. According to the system, a comprehensive analysis process aiming at the asphalt microparticles and the tire wear microparticles is established, and the system has important significance in evaluating environmental behaviors of the microparticles on the asphalt pavement.