Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

18 results about "Ketosis" patented technology

Ketosis is a metabolic state characterized by elevated levels of ketone bodies in the blood. Physiologic ketosis is a normal response to low glucose availability, such as low-carbohydrate diets or fasting, that provides an additional energy source for the brain in the form of ketones. In physiologic ketosis, ketones in the blood are elevated above baseline levels but the body's acid-base homeostasis is maintained. This contrasts with ketoacidosis, an uncontrolled production of ketones that occurs in pathologic states and causes a metabolic acidosis, which is a medical emergency. Ketoacidosis is most commonly the result of complete insulin deficiency in type 1 diabetes or late-stage type 2 diabetes.

Ketogenic compositions and methods of use thereof

Compositions and methods for providing a person with an exogenous and therapeutically effective supply of short chain fatty acids, chlorogenic acid, and, optionally, ketones are disclosed. The compositions include one or more short chain fatty acids (such as butyric acid, butyrate salts, propionic acid, propionate salts, acetic acid, or acetate salts); chlorogenic acid; and, optionally, one or more beta-hydroxybutyrate salts. The compositions and methods are useful for inducing ketosis and / or beta-oxidative activity in a subject. In addition, compositions that include concentrated forms of, and methods of using, chlorogenic acid (alone or in combination with short chain fatty acids and ketones) to induce ketogenesis in a subject are disclosed.
Owner:CAVALERI HEALTH INC

Methods to improve health and wellbeing in ruminants

The present invention is in the field of animal feed, feed supplements, premixes, and feed additives, more particular for ruminants, even more particular for improvement of metabolism and overall health, wellbeing and longevity of a ruminant animal. Provided are methods to increase circulating glucose levels in the blood, to decrease circulating beta-hydroxybutyrate, to reduce the risk of ketosis, and to prevent inflammation in a ruminant.
Owner:NUTRECO IP ASSETS BV

Traditional Chinese medicine composition for preventing and treating ketosis of dairy cows, oral liquid, preparation method and application thereof

The application provides a traditional Chinese medicine composition for preventing and treating ketosis of dairy cows, an oral liquid, a preparation method and application thereof, and belongs to the field of veterinary products. Active ingredients of the application include the following raw materials in parts by weight: 30-40 parts of rhizoma polygonati, 20-35 parts of cortex lycii, 15-25 parts of curcuma, 15-25 parts of rehmannia glutinosa, 5-15 parts of dioscorea, 5-15 parts of chicory, 5-15 parts of taraxacum, 5-10 parts of motherwort, and 5-10 parts of citrus reticulata. The composition of the application is reasonably matched, has synergistic effects, fully plays the role of each medicine, and has obvious effects on preventing and treating ketosis of dairy cows.
Owner:BEIJING CENT BIOLOGY CO LTD +3

Oral liquid for preventing and treating perinatal energy metabolism disorder disease of dairy cows and preparation method thereof

ActiveCN118717892BPhysiologyMilk cow's
The present application relates to the technical field of oral liquid, in particular to a kind of oral liquid for preventing and treating perinatal energy metabolism disorder disease of dairy cow and preparation method thereof, it is characterized in that, the oral liquid for preventing and treating perinatal energy metabolism disorder disease of dairy cow is made of the following components, by weight parts: artemisia capillaris 200~300 parts, gardenia 150~200 parts, bupleurum 100~150 parts, polygonatum 50~100 parts, radix paeoniae alba 50~100 parts, liquorice 10~50 parts, nicotinic acid 1~10 parts, propylene glycol 200~300 parts, fructose diphosphate sodium 1~10 parts, pure water 200~400 parts.The oral liquid for preventing and treating perinatal energy metabolism disorder disease of dairy cow can prevent and treat ketosis, fatty liver and liver damage at the same time, comprehensively improve the constitution of new cow, improve immunity, improve physical indicators and reproductive performance, increase economic benefits.
Owner:ZHENGZHOU BARY ANIMAL PHARMA

Method and system for carrying out antenatal early warning on ketosis of dairy cow by using electronic nose

The invention discloses a method and system for prenatal early warning of cow ketosis by using an electronic nose, and the method comprises the steps: S1, collecting cow excrement samples 21-14 days before delivery, synchronously collecting blood samples 3-14 days after delivery, detecting the concentration of beta-hydroxybutyric acid, and dividing a healthy group and a ketosis group according to a preset beta-hydroxybutyric acid concentration threshold; s2, based on the excrement samples of the healthy group and the ketosis group, odor sensor response values of the excrement samples are collected through an electronic nose, an odor mark map is obtained, and a plurality of sensor arrays with significant differences are obtained through screening; s3, based on the data of the plurality of sensor arrays with significant differences, an RF (Random Forest) algorithm is adopted to construct an early warning model; and S4, inputting to-be-detected data into the early warning model, and outputting a ketosis risk prediction result. According to the method, antenatal early warning is achieved through non-invasive excrement VOCs analysis, the method has the advantages of being convenient to operate, efficient in detection, economical, environmentally friendly and the like, and a reliable early health monitoring scheme is provided for a large-scale pasture.
Owner:GANSU AGRI UNIV

An organic trace element compound package for lactating cows and a preparation method and application thereof

PendingCN122296399AImprove lactation performanceincrease milk productionPhysiologySodium iodide
This invention discloses an organic trace element complex for lactating dairy cows, comprising the following components in parts by weight: 40-70 parts of hydroxymethionine complex, 0.1-0.2 parts of sodium iodide, 30-45 parts of yeast selenium, 0.1-0.2 parts of cobalt sulfate, 10-25 parts of synergist, and 5-10 parts of carrier. This invention also discloses the preparation method and application of the above-mentioned organic trace element complex. When used in lactating dairy cows, the various hydroxymethionine complexes can effectively pass through the rumen to the small intestine and be absorbed through amino acid channels, meeting the needs of dairy cows for various trace elements during lactation. The synergistic effect of the various hydroxymethionine complexes and the synergist can improve the lactation performance of dairy cows, increase milk production, enhance the body's resistance, significantly reduce the incidence of mastitis and hoof diseases, and alleviate ketosis.
Owner:XINGJIA BIO ENG CO LTD

Dairy cow ketosis prevention and control monitoring and early warning method and system based on perinatal period blood indexes

The invention relates to the technical field of livestock disease prevention and control early warning, and discloses a dairy cow ketosis prevention and control monitoring early warning method and system based on a perinatal period blood index, and the method comprises the steps: collecting a perinatal period dairy cow blood sample, and obtaining a metabolite feature set; obtaining health state information of the dairy cow; then obtaining a health state mark data set; outputting a ketosis prediction result of the currently detected dairy cow through the ketosis prediction model; the health change trend of the dairy cow is obtained, different individual intervention strategies are planned, the individual intervention strategies are accurately matched with the current health state stage of the dairy cow, and the optimal intervention scheme is obtained. According to the application, prospective, dynamic and precise prevention and control of ketosis can be realized, so that nutrition regulation and control are precisely matched with individual metabolic response, and the prospective, individualized and economical efficiency of prevention and control of perinatal metabolic diseases is remarkably improved.
Owner:LIAONING PROVINCIAL ANIMAL DISEASE PREVENTION & CONTROL CENT

Treatment of motor disorders in glucose transporter type 1 deficiency syndrome without inducing ketosis

PendingCA3317632A1PhysiologyTriglyceride
This invention relates to the treatment of glucose transporter type 1 deficiency syndrome (Glut1-DS). In particular, the invention relates to specific medium-chain triglyceride compositions, enriched for C10 (decanoic acid), for use in treating movement disorders in Glut1-DS patients.
Owner:VITAFLO INT +1

Method and device for determining ketosis morbidity

ActiveEP4184146B1Disease diagnosisUsing mechanical meansDisease ratesKetosis
An object of the present invention is to make it possible to easily determine a presence or absence of ketosis and / or the possibility of ketosis in an animal on site or the like. Another object of the present invention is to provide an apparatus for performing the determination. A method for determining ketosis according to one embodiment of the present invention includes providing gas detection means with a gas generated from a body fluid collected from an animal (except for humans), and determining ketosis of the animal based on a composition of the gas generated from the body fluid using a response of the gas detection means to the gas generated from the body fluid.
Owner:NAT INST FOR MATERIALS SCI

Efficacious increase of ketone levels in a human body and synthesis of novel compositions of ketone body analog esters for use as a dietary supplement

PendingUS20260248755A1Dietary supplementNutrition
Methods of efficaciously increasing ketone body levels in a human bloodstream, thereby supporting various health benefits associated with ketosis, including improved metabolic health and enhanced endurance performance. Compositions including mixtures of esters that are used by a user's body to create ketosis related molecules in the blood stream are disclosed. Methods of forming the mixtures and exemplary starting materials are disclosed. Compositions may comprise mixtures of ketone body analog esters designed for nutritional supplementation. Compositions include esters such as 3-Hydroxy-3-methylbutyl 3-oxobutanoate and(S)-3-Hydroxybutyl 3-oxobutanoate, which mimic the physiological effects of natural ketosis. The present invention includes methods for synthesizing compositions through reactions involving 1,3-Butanediol, 3-Hydroxy-3-methylbutanol, and various acids in the presence of enzyme systems. Resulting esters enhance energy metabolism, support muscle recovery, promote cognitive function, and aid in weight management. Compositions may be tailored by adjusting reactant ratios and reaction conditions, offering flexibility in achieving desired ester profiles.
Owner:KETONE CATALYST INNOVATIONS LLC

Treatment of motor disorders in glucose transporter type 1 deficiency syndrome without inducing ketosis

PendingAU2025211254A1PhysiologyTriglyceride
This invention relates to the treatment of glucose transporter type 1 deficiency syndrome (Glut1-DS). In particular, the invention relates to specific medium-chain triglyceride compositions, enriched for C10 (decanoic acid), for use in treating movement disorders in Glut1-DS patients.
Owner:VITAFLO INT +1

Compositions containing short-chain fatty acid, methods of use, and methods of making thereof

A food product comprises L-lysine butyrate. The food product does not contain gluten and is not a baked product. Alternatively, the product is an oral dosage form comprising 25 mg to 5.0 g L-lysine butyrate. The oral dosage form is a tablet, a capsule, or a sealed packet containing powder. In another alternative, orally administering L-lysine butyrate may be used to: supplementing butyrate, provide a nootropic effect, treat a condition, losing weight, improve cognition, induce or maintain ketosis, improve athletic performance, or treat or mitigate mild-to-moderate pain.
Owner:VELOCITY LIFE SCIENCES LLC

Compositions containing short-chain fatty acid, methods of use, and methods of making thereof

A food product comprises L-lysine butyrate. The food product does not contain gluten and is not a baked product. Alternatively, the product is an oral dosage form comprising 25 mg to 5.0 g L-lysine butyrate. The oral dosage form is a tablet, a capsule, or a sealed packet containing powder. In another alternative, orally administering L-lysine butyrate may be used to: supplementing butyrate, provide a nootropic effect, treat a condition, losing weight, improve cognition, induce or maintain ketosis, improve athletic performance, or treat or mitigate mild-to-moderate pain.
Owner:VELOCITY LIFE SCIENCES LLC

Compositions containing a non-xanthine CNS stimulant or nootropic and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance

Disclosed herein are compositions that include a combination of: (1) a non-xanthine CNS stimulant or nootropic; (2) a ketone body or ketone body precursor, such as beta-hydroxybutyrate (BHB) salt, BHB ester, BHB acid, acetoacetate salt, acetoacetate ester, acetoacetic acid, 1,3-butanediol, medium chain fatty acid, or ester of medium chain fatty acid; and (3) optionally a dietetically or pharmaceutically acceptable carrier. The composition may include a vasodilator. The composition may include a short or medium chain fatty acid or ester thereof in addition to or instead of the ketone body or ketone body precursor. The composition can provide enhanced cognitive flexibility, improved sustained attention, improved working memory, and neuroprotection in a mammal. The composition can also beneficially increase resting energy expenditure (resting metabolic rate), particularly when in a state of ketosis, enhancing fat loss principally through ketosis while promoting muscle formation and maintenance, as well as modulating lethargy / lightheadedness when entering a ketogenic state.
Owner:AXCESS GLOBAL SCIENCES LLC

Compositions comprising paraxanthine and beta-hydroxybutyric acid or precursors for improving neurological and physiological properties

Disclosed herein is a "paraxanthine-BHB" composition comprising the following combinations: (1) paraxanthine; (2) a BHB ketone body component, such as a beta-hydroxybutyric acid (BHB) salt, a BHB ester or a BHB acid; and (3) an optionally dietary or pharmaceutically acceptable carrier. In addition to BHB, a BHB precursor, such as 1, 3-butanediol, may also be used, or the BHB may be replaced with the precursor. Also disclosed herein are methods of using such compositions for producing a desired physiological effect in a mammal, such as enhanced cognitive flexibility, improved persistent attention, improved working memory, and neuroprotection. In addition to this improved mental sensitivity profile, the composition may also beneficially increase resting energy consumption (resting metabolic rate), increase fat consumption primarily by ketosis, while promoting muscle formation and maintenance, and modulate sleepiness / dizziness when entering a ketosis state.
Owner:AXCESS GLOBAL SCIENCES LLC

Method and apparatus for determining ketosis

An object of the present invention is to make it possible to easily determine a presence or absence of ketosis and / or the possibility of ketosis in an animal on site or the like. Another object of the present invention is to provide an apparatus for performing the determination. A method for determining ketosis according to one embodiment of the present invention includes providing gas detection means with a gas generated from a body fluid collected from an animal (except for humans), and determining ketosis of the animal based on a composition of the gas generated from the body fluid using a response of the gas detection means to the gas generated from the body fluid.
Owner:NAT INST FOR MATERIALS SCI

Dairy cow health state monitoring method based on food intake

The invention belongs to the technical field of breeding, and particularly relates to a dairy cow health state monitoring method based on food intake, which comprises the following steps: S1, continuously acquiring the single-day food intake of an individual dairy cow on N days, and generating a basic health score based on the change trend of the food intake; s2, dynamically correcting the basic health score in combination with cow behavior data and environment / metabolism parameters to form a final health score; and S3, forming a grading early warning signal based on the final health score, generating an intervention instruction based on the grading early warning signal, and mastering the health state of the dairy cow and measures required to be taken for the health state through the early warning signal, thereby improving the response convenience and judgment reliability of the health risk of the dairy cow, and improving the safety of the dairy cow. The method can be used for efficiently monitoring the health state of the single dairy cow in the group of dairy cows, and has timely early warning and intervention effects on possible outbreak metabolic diseases (such as ketosis and acidosis).
Owner:NINGXIA UNIVERSITY