122 results about "Ketosis" patented technology

Ketogenic compositions including a beta-hydroxybutyrate (BHB) mixed salt are formulated to induce or sustain ketosis in a subject to which the ketogenic compositions are administered. The BHB mixed salt is formulated to provide a biologically balanced set of cationic electrolytes, and is formulated to avoid detrimental health effects associated with imbalanced electrolyte ratios. A ketogenic composition includes BHB salts of at least sodium, potassium, calcium, and magnesium. The BHB salts may also include at least other component such as a BHB compound containing other cations, such as transition metal cations (e.g., zinc or iron), a BHB-amino acid salts, medium chain fatty acid source, vitamin D₃, flavorant, or other excipient.

The invention discloses a nutrition regulating and controlling additive special for dairy cattle in a perinatal period, which consists of rumen bypass fat 300-400g/kg, vitamin A 500,000-600,000 IU, vitamin E 5000-6000 IU, selenium 3-5mg/kg, compound Chinese herbal medicine 100-200g/kg and the balance carrier, wherein the compound Chinese herbal medicine is prepared by mixing, by weight, 10% of astragalus mongholicus, 10% of codonopsis pilosula, 5% of rhizoma cyperi, 5% of rhizoma atractylodis, 10% of angelica sinensis, 10% of radix paeoniae alba, 10% of rehmannia glutinosa, 10 % of herba epimedii, 10% of beautiful sweetgum fruit, 10% of cowherb seed and 10% of leonurus. The nutrition regulating and controlling additive special for the dairy cattle in the perinatal period has the advantages of being high in technological content, full in nutrition, comprehensive in functions, remarkable in effect and capable of improving energy negative balance state of postpartum dairy cattle and promoting body condition recovery, improves immune functions of the dairy cattle in the perinatal period, enhances disease resistance, reduces incidence of mammitis, endometritis, ketosis, puerperal feverand other diseases of the postpartum dairy cattle, promoting postpartum quick oestrus and improving reproductive performance.

The present invention relates to novel 3-azabicyclo[3.1.0]hexane derivatives as dipeptidyl peptidase-IV inhibitors and the processes for the synthesis of the said compounds. This invention also relates to pharmacological compositions containing the compounds of the present invention, and methods of treating diabetes, especially type 2 diabetes, as well as prediabetes, diabetic dyslipidemia, metabolic acidosis, ketosis, satiety disorders, and obesity. These inhibitors can also be used to treat conditions manifested by a variety of metabolic, neurological, anti-inflammatory, and autoimmune disorders like inflammatory disease, multiple sclerosis, rheumatoid arthritis; viral, cancer and gastrointestinal disorders. The compounds of this invention can also be used for treatment of infertility arising due to polycystic ovary syndrome.

The invention discloses a postpartum new dairy cow drenching nutritious supplementary and application thereof in a nutritious supplementary for treating postpartum hypocalcemia, abomasum displacement or ketosis disease of dairy cow. The nutritious supplementary provided by the invention is capable of effectively maintaining the levels of blood calcium, blood magnesium and glucose and reducing the levels of NEFA (Non-Esterified Fatty Acid) and beta-hydroxybutyric acid, thereby effectively reducing the occurrence rate of metabolic diseases of postpartum paralysis, ketosis, abomasum displacement and the like of new dairy cow. As a result, the dairy cow can be rehabilitated in physical power and food intake quickly, and the health condition of the dairy cow can be improved and the milk yield of the dairy cow can be increased; and good economic benefit can be achieved.

The present invention provides anionic-containing feed supplements having a low protein by-pass value that may be administered to animals. In particular, the invention provides anionic-containing feed supplements that are granular and may be utilized to treat several metabolic disorders in animals, such as hypocalcemia, milk fever, and ketosis.

The present invention relates to dimensionally stable low carbohydrate pet food products and method for producing such products. The resulting pet food products are capable of inducing desired levels of ketosis in pets which in turn can lead to weigh loss or weight control.

The invention relates to rumen glucose, which is a rumen particle prepared from glucose by a microcapsule enveloping technique so that the glucose is not degraded in the rumen and is effectively released in intestinal canals. The enveloped substance not only can effectively treat bovine ketosis, but also can effectively prevent ketoses, and can provide rumen carbohydrates for cattle to improve the milk yield at the same time.

The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease malignant brain cancer, and other cancers, which are associated with metabolic dysregulation. The administration of a ketogenic diet, such as ketone esters, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment resulted in therapeutic ketosis. Optionally, the hyperbaric, oxygen-enriched environment is 100% oxygen at 2.5 ATA absolute. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two. The treatment may further include administering at least 10% ketone supplementation, such as acetoacetate, adenosine monophosphate kinase, 1,3-butanediol, or ketone ester, to the patient.

The invention relates to drinking mixed feed after cow calving, which comprises a liquid component and a solid component; during application, the liquid component can be dissolved in 30-50 kg of saline water for oral administration or gavage of postpartum cow, and the solid component is also added; the liquid component is 500 ml, and comprises, by mass, 40-70% of propylene glycol, 20-40% of glycerin, and 10-20% of water; the solid component is 500 g, and comprises, by mass, 12-20% of calcium propionate, 26-34% of calcium gluconate, 12-20% of potassium chloride, 12-20% of sodium chloride, 6-12% of magnesium sulfate, 8-16% of sodium bicarbonate. The beneficial effects of the present invention are that: hypocalcemia and milk fever prevention; cow ketosis or low appetite prevention; blood acid-base balance improvement; bedridden syndrome due to magnesium deficiency prevention; feed digestion rate improvement and feed intake increase.

The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease and malignant brain cancer, which are associated with metabolic dysregulation. The administration of ketone esters resulted therapeutic ketosis and neuroprotection against seizures resulting from CNS oxygen toxicity. Supplemental ketones were also found to reduce superoxide production in cultured cortex neurons exposed to hyperbaric oxygen and Aβ-42, and to decrease proliferation and viability in U87 glioma cells. These observations support the therapeutic effect of ketones for seizure disorders, Alzheimer's disease and malignant brain cancer. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two.

The invention relates to a traditional Chinese medicine composition for treating cow ketosis. The traditional Chinese medicine composition is prepared from the following ingredients in parts by weight: 75-85 parts of radix codonopsitis, 75-85 parts of rhizoma atractylodis, 55-65 parts of radix astragali, 55-65 parts of honeysuckle, 95-105 parts of ordate houttuynia, 45-55 parts of tuckahoe, 55-65 parts of angelica, 45-55 parts of motherwort, 35-45 parts of hemlock parsley, 55-65 parts of red paeonia, 55-65 parts of prepared rehmannia root, 75-85 parts of fructus amomi, 35-45 parts of jujube kernel, 35-45 parts of poria with hostwood, 25-35 parts of milkwort, 45-55 parts of fried fennel, 45-55 parts of costus root, 95-105 parts of medicated leaven, 45-55 parts of Atractylis ovata, 55-65 parts of Magnolia officinalis, 45-55 parts of bitter orange and 45-55 parts of licorice. The combination and preparation method of the traditional Chinese medicine composition provided by the invention are simple, and the traditional Chinese medicine composition has low cost and is safe and reliable; after the traditional Chinese medicine composition is administered, the symptoms of the cow suffering from ketosis is rapidly alleviated, the cow rapidly recovers, and the curative effect is obvious; and 58 cases of the cows suffering from ketosis are treated with the traditional Chinese medicine, and the curative rate reaches 86%.

The invention discloses a formula of bypass rumen protection niacin for preventing dairy cow ketosis and a preparation method. The formula comprises a coating and a coated core, wherein the coating adopts rumen fatty powder; the active composition of the coated core adopts niacin; and the ratio of the coating to the coated core is (40-70): (30-60). The formula ensures that the active composition niacin is efficiently absorbed by a dairy cow through a bypass rumen coating technology, improves the feed intake of the dairy cow, further reduces the incidence rates of perinatal diseases, such as ketosis, fatty liver and left displaced abomasums, of the dairy cow, increases the milk production of the dairy cow, and realizes cost decreasing and benefit increasing for a pasture, and the niacin has the effects of restraining body fat mobilization of the dairy cow and improving the dry matter intake of the dairy cow; the formula greatly reduces the degradation of the active composition niacin in the rumen of the dairy cow; the coating technology is reasonable, coating is uniform and complete, bypass rumen effect is ideal, the niacin content is high, the niacin has an ideal physical form, the particles are small and even, the flowability is high, and the niacin is easy to directly use in production.

Ketoacidosis is an extreme and uncontrolled form of ketosis, which is a normal response to prolonged fasting. Embodiments of this invention test the ketone level of a patient by measuring the ketone bodies in breath condensation. Some embodiments include a device for medical testing comprising a hollow container, comprising powder mixture of sodium nitroferricyanide, ammonium sulfate and silica and a liquid including an ammonium hydroxide solution.