10 results about "Deficiency syndrome" patented technology

The invention discloses a medicinal and edible traditional Chinese medicine composition for postoperative rehabilitation as well as a preparation method and application of the medicinal and edible traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 12 to 27 parts of radix astragali seu hedysari, 2 to 10 parts of radix ginseng, 2 to 10 parts of colla corii asini, 5 to 18 parts of radix angelicae sinensis, 8 to 25 parts of cortex eucommiae, 5 to 18 parts of semen persicae, 23 to 37 parts of small red beans, 8 to 25 parts of pericarpium citri reticulatae, 23 to 37 parts of fructus ziziphi jujubae, 2 to 10 parts of rhizoma zingiberis recens and 8 to 25 parts of semen ziziphi spinosae. The traditional Chinese medicine composition has the effects of tonifying qi and nourishing blood, promoting blood circulation to remove blood stasis and strengthening the spleen and stomach, integrates the effects of tonifying qi and nourishing blood, warming and dredging to remove blood stasis and strengthening the spleen and soothing the nerves in one formula, can cover common deficiency syndrome types, and breaks through the limitation of traditional Chinese medicine individualized dialectical treatment in popularization.

The present invention relates to a novel antisense transcript to the human SLC2A1 (Glut1) gene, variants and fragments thereof. This antisense transcript can be used to modulate Glut1 expression and serve to restore Glut1, and as a therapeutic for treating or preventing Glut 1 deficiency syndrome, or other Glut1 related conditions including certain cancers, diabetes, Alzheimer's disease, and retinitis pigmentosa.

The present application relates to the technical field of medicine, and especially relates to a combined Chinese and western medicine composition and application thereof, wherein the combined Chinese and western medicine composition comprises Chinese patent medicine and western medicine; the raw material of the Chinese patent medicine comprises Strychnos seed powder, Earthworm, Codonopsis, Poria cocos, Atractylodes, Chuanxiong, Salvia miltiorrhiza, Panax notoginseng, Radix et Rhizoma Bovis, and Radix Glycyrrhizae; and the effective component of the western medicine is diclofenac; the application of the combined Chinese and western medicine composition in preparation of a lumbar pain medicine; the application is for preparation of intervertebral disc-derived lumbar pain medicines of different syndromes; the syndrome is preferably qi and blood deficiency syndrome; the combined Chinese and western medicine composition can effectively treat intervertebral disc-derived lumbar pain of different syndromes through mutual cooperation between the Chinese patent medicine and the western medicine, and the curative effect is more obvious for intervertebral disc-derived lumbar pain of qi and blood deficiency syndrome.

This invention relates to the treatment of glucose transporter type 1 deficiency syndrome (Glut1-DS). In particular, the invention relates to specific medium-chain triglyceride compositions, enriched for C10 (decanoic acid), for use in treating movement disorders in Glut1-DS patients.

The application belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating metabolic-related fatty liver disease of liver stagnation and spleen deficiency syndrome, which is composed of the following raw materials by weight: 8-10 parts of ginseng, 10-15 parts of bupleurum, 10-15 parts of curcuma zedoary, 6-9 parts of pinellia, 6-10 parts of amomum, 10-15 parts of atractylodes, 10-15 parts of poria, 10-15 parts of hovenia dulcis, 10-15 parts of rehmannia, 8-10 parts of giant knotweed, and 6-9 parts of olibanum. The traditional Chinese medicine composition treats metabolic-related fatty liver disease from the perspective of liver stagnation and spleen deficiency and phlegm and blood stasis, and starts from the core pathological chain of liver stagnation, spleen deficiency, phlegm and blood stasis, and has the functions of soothing liver and strengthening spleen, removing dampness and fat, and activating blood and dredging collaterals. The traditional Chinese medicine composition is especially suitable for patients with metabolic-related fatty liver disease of liver stagnation and spleen deficiency syndrome. Clinical tests prove that the traditional Chinese medicine composition has good therapeutic effect on patients with metabolic-related fatty liver disease of liver stagnation and spleen deficiency syndrome, and the total effective rate is more than 94%. The traditional Chinese medicine composition has mild medicinal properties, good safety, stable curative effect, and is not easy to relapse, and is suitable for long-term taking.

This invention relates to the treatment of glucose transporter type 1 deficiency syndrome (Glut1-DS). In particular, the invention relates to specific medium-chain triglyceride compositions, enriched for C10 (decanoic acid), for use in treating movement disorders in Glut1-DS patients.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating post-infection irritable bowel syndrome as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 15 parts of rhizoma atractylodis macrocephalae, 10 to 20 parts of radix paeoniae alba, 3 to 7 parts of pericarpium citri reticulatae, 5 to 15 parts of radix saposhnikoviae, 10 to 20 parts of folium microcotis, 10 to 20 parts of plumeria rubra, 5 to 15 parts of kapok, 25 to 35 parts of rhizoma smilacis glabrae and 5 to 15 parts of flos albiziae. Animal experiments show that the traditional Chinese medicine composition can effectively improve diarrhea phenotypes and depressive symptoms of rats with PI-IBS liver depression and spleen deficiency syndromes, relieve high sensitivity of viscera, recover a tight junction structure and a cell desmosome structure of colon, up-regulate cell TJ protein expression, recover Th1 / Th2 immune imbalance of blood, reduce the level of proinflammatory factors (TNF-alpha) in colon tissue, and improve the immunity of the rats. And the levels of LPS, DAO and D-LA in serum are up-regulated. Therefore, the traditional Chinese medicine composition disclosed by the invention can be used for effectively treating the liver depression and spleen deficiency syndrome of the irritable bowel syndrome after infection.

According to the RA traditional Chinese medicine syndrome typing based on the protein antibody chip technology and application, the protein antibody chip technology is applied to RA traditional Chinese medicine syndrome typing for the first time, and high-throughput and multi-target detection is achieved. Key markers such as IL-6R and TIMP-2 are found, and the combination of the key markers can remarkably improve the syndrome distinguishing accuracy; compared with single ELISA detection, the protein antibody chip technology can analyze 40 inflammatory factors at the same time, and the efficiency is greatly improved. In combination with bioinformatics, molecular characteristics of the damp-heat blockage syndrome and the liver and kidney deficiency syndrome are disclosed; an objective laboratory basis is provided for traditional Chinese medicine differentiation of RA, and clinical precise typing and individualized treatment are assisted.

The present application relates to a kind of traditional Chinese medicine composition for treating spleen deficiency syndrome heart failure with cognitive dysfunction, including the following weight parts of traditional Chinese medicine composition: 18-22 parts of Huangqi, 8-12 parts of Renshen, 13-17 parts of Baishu, 13-17 parts of Shanyao, 13-17 parts of Fuling, 8-12 parts of Zexie, 8-12 parts of Huangjing, 8-12 parts of Danggui, 8-12 parts of Chuanqiong, 8-12 parts of Maidong, 8-12 parts of Zhimu, 5-7 parts of Wuyi, 8-12 parts of Chenpi, 5-7 parts of Guizhi, 8-12 parts of Hongjingtian, 10-14 parts of Wujiapi and 5-7 parts of Zhigancao.The preparation method of the present application is mainly decoction and granulation.The present application is suitable for spleen deficiency syndrome, such as fatigue, chest tightness, dyspnea, edema, dizziness, palpitation, abdominal distension, poor appetite, or cold, weak or loose stool, difficult urination, dull expression, slow speech and action, and other symptoms.Specifically suitable for heart failure with cognitive dysfunction with the above symptoms.

The invention relates to the field of traditional Chinese medicine, in particular to a liver depression and spleen deficiency syndrome animal model evaluation method and application thereof. The invention provides an RMS-LSCRS scale tool, which is a model recording and evaluating tool specially developed for a chronic bound stress liver depression and spleen deficiency syndrome rat model. By using an RMS-LSCRS scale tool, detailed qualitative and quantitative recording can be carried out on the modeling condition of the model developed by the rat model with the chronic constraint stress liver depression and spleen deficiency syndrome, and qualitative and quantitative evaluation can be carried out on the rat model so as to judge the success condition of modeling.