Yang-tonifying and sinew-strengthening composition for tonifying spleen and kidney and strengthening muscles and bones and preparation method of yang-tonifying and sinew-strengthening composition

Abstract

The invention discloses a yang-tonifying and tendon-strengthening composition for tonifying spleen and kidney and strengthening muscles and bones and a preparation method of the yang-tonifying and tendon-strengthening composition. The composition for tonifying yang and strengthening tendons is prepared from the following raw materials: 20 to 80g of flos chrysanthemi, 1 to 6g of radix ginseng, 4 to 18g of poria cocos, 1.5 to 8g of rhizoma dioscoreae, 4 to 18g of radix astragali seu hedysari, 2 to 10g of rhizoma atractylodis macrocephalae, 1 to 6g of pericarpium zanthoxyli, 4 to 18g of fructus mori, 4 to 28g of fructus lycii, 3 to 15g of cortex eucommiae, 4 to 28g of radix morindae officinalis, 3 to 15g of semen cuscutae, 4 to 28g of radix rehmanniae praeparata, 2 to 10g of radix rehmanniae recen, 4 to 28g of radix angelicae sinensis and 1.5 to 8g of radix polygalae. Compared with the prior art, the preparation method is improved, flavone components and polysaccharide components in the traditional Chinese medicinal materials are dissolved in the medicament to prepare the yang-tonifying and tendon-strengthening drink or the yang-tonifying and tendon-strengthening pill, the kidney-deficiency syndrome and the lumbago disease caused by kidney deficiency are jointly treated through the principle of monarch, minister, assistant and guide, and creatinine and urea are obviously reduced after the medicament is applied.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine, and in particular to a yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidney and tendons and bones and a preparation method thereof. Background Art

[0002] Low back pain due to kidney deficiency is a disease caused by straining the kidney or being physically weak, which leads to kidney deficiency. The kidney's essence cannot nourish the tendons, bones and meridians, resulting in poor blood circulation or blood stasis in the meridians, which makes the tendons uncomfortable and causes pain in the waist. At present, the number of low back pain due to kidney deficiency is gradually increasing due to unhealthy lifestyles. Bad habits such as staying up late for a long time, drinking too much, sitting still for a long time, and looking down at the phone overload the liver and kidneys, causing kidney yin deficiency and internal fire. Kidney deficiency can cause osteopenia, weak tendons and bones, and overburden the waist and neck muscles, causing soreness of the waist and knees, fatigue, mental fatigue, and diffuse pain on one or both sides of the neck or waist and buttocks.

[0003] At present, Chinese medicine mainly uses massage, acupuncture or external application to treat the disease. Although it can relieve the pain, it only treats the symptoms and not the root cause. The main problem is that the kidney qi is weak, but it has not received due attention, resulting in repeated recurrences of kidney deficiency and low back pain. Summary of the invention

[0004] The object of the present invention is to provide a yang-tonifying and tendon-strengthening composition for invigorating the spleen and kidney and strengthening the tendons and bones.

[0005] The present invention also aims to provide a method for preparing a yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys, tendons and bones.

[0006] To achieve the above-mentioned purpose, the present invention provides a yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidney and tendons, and strengthening the tendons and bones. The raw materials of the yang-tonifying and tendon-strengthening composition include, by weight, 20-80g of chrysanthemum, 1-6g of ginseng, 4-18g of Poria, 1.5-8g of yam, 4-18g of astragalus, 2-10g of atractylodes, 1-6g of Zanthoxylum bungeanum, 4-18g of mulberry, 4-28g of wolfberry, 3-15g of eucommia, 4-28g of Morinda officinalis, 3-15g of Cuscuta australis, 4-28g of Rehmannia root, 2-10g of Rehmannia root, 4-28g of Angelica sinensis and 1.5-8g of Polygala tenuifolia.

[0007] Preferably, in the above technical scheme, the raw materials of the yang-tonifying and tendon-strengthening composition include, by weight, 24-72g chrysanthemum, 1.5-4.5g ginseng, 5-15g poria, 2-6g yam, 5-15g astragalus, 3-9g atractylodes, 1.5-4.5g zanthoxylum, 5-15g mulberry, 8-24g wolfberry, 4-12g eucommia, 8-24g morinda officinalis, 4-12g dodder seed, 8-24g rehmannia root, 3-9g raw rehmannia root, 8-24g angelica and 2-6g polygala.

[0008] Preferably, in the above technical scheme, the raw materials of the yang-tonifying and tendon-strengthening composition include, by weight, 48g chrysanthemum, 3g ginseng, 10g poria, 4g yam, 10g astragalus, 6g atractylodes, 3g zanthoxylum, 10g mulberry, 16g wolfberry, 8g eucommia, 16g morinda officinalis, 8g dodder seed, 16g rehmannia root, 6g raw rehmannia root, 16g angelica and 4g polygala.

[0009] The medicinal properties, meridians and efficacy of the Chinese medicinal materials used in the present invention are as follows:

[0010] Chrysanthemum: Chrysanthemum is a traditional Chinese medicine that can be used as both medicine and food. It tastes spicy, bitter, and sweet, and is slightly cold in nature. It enters the lung and liver meridians. Chrysanthemum contains ingredients such as chrysanthemic acid, chlorogenic acid, and chrysanthemum glycosides, which have the effects of dispersing wind-heat, calming liver yang, calming the liver, improving eyesight, and clearing away heat and detoxifying.

[0011] Ginseng: Ginseng is a traditional Chinese medicine that can be used as both medicine and food. It tastes sweet, slightly bitter, and slightly warm in nature. It enters the spleen, lung, kidney, and heart meridians. Ginseng mainly contains ingredients such as ginsenosides, ginsenosides, and ginseng polysaccharides, which have the effects of greatly replenishing vital energy, restoring pulse and strengthening deficiency, nourishing the spleen and lungs, promoting fluid and nourishing blood, and calming the mind and improving intelligence.

[0012] Atractylodes macrocephala: Atractylodes macrocephala is a Chinese medicinal material that can be used as both medicine and food. It tastes sweet and bitter, and is warm in nature. It enters the spleen and stomach meridians. Atractylodes macrocephala mainly contains ingredients such as atractylodes lactone I, atractylodes lactone II, and atractylodes lactone III, which have the effects of drying dampness, promoting diuresis, stopping sweating, and calming the fetus.

[0013] Astragalus: Astragalus is a traditional Chinese medicine that can be used as both medicine and food. It tastes sweet and is slightly warm in nature. It enters the spleen and lung meridians. Astragalus contains main ingredients such as formononetin, calycosin, astragaloside and soybean saponin, which have the effects of replenishing qi and raising yang, strengthening the body's defense system, promoting diuresis and reducing swelling, and promoting the production of body fluids and nourishing blood.

[0014] Dried mulberry: Dried mulberry is a traditional Chinese medicine that can be used as both medicine and food. It tastes sweet and sour, and is cold in nature. It enters the heart, liver, and kidney meridians. Dried mulberry contains anthocyanins, resveratrol, malic acid, and succinic acid, which can nourish the heart, liver, and kidney, nourish yin and blood, promote the production of body fluids and moisturize the internal organs, resist aging, and improve immunity.

[0015] Rehmannia root: Rehmannia root is a traditional Chinese medicine that is both a medicine and a food. It tastes sweet and is slightly warm in nature. It enters the liver and kidney meridians. Rehmannia root contains main ingredients such as motherwort glycosides, aucubin, and rehmannia glycosides, which have the effects of nourishing blood, nourishing yin, and replenishing essence and marrow.

[0016] Raw Rehmannia root: Raw Rehmannia root is a traditional Chinese medicine that is both a medicine and a food. It tastes sweet and bitter, and is cold in nature. It enters the heart, liver, and kidney meridians. Raw Rehmannia root contains ingredients such as rehmannia glycosides, catalpol, and dihydrocatalpol. It is a heat-clearing and blood-cooling medicine with the effects of clearing heat and cooling blood, nourishing yin, and promoting the production of body fluids.

[0017] Poria cocos: Poria cocos is a traditional Chinese medicine that can be used as both medicine and food. It tastes sweet and light, and is neutral in nature. It enters the heart, lung, spleen, and kidney meridians. Poria cocos is the dried sclerotium of the fungus Poriacocos (Schw.) Wolf of the Polyporaceae family. The one produced in Yunnan is called "Yunling" and is of better quality. Poria cocos contains the main ingredients of β-pachymannan, pachymic acid, etc., which has the effects of promoting diuresis and eliminating dampness, strengthening the spleen, and calming the mind.

[0018] Angelica: Angelica is a Chinese herbal medicine that is both a medicine and a food. It tastes sweet and spicy, and is warm in nature. It enters the liver, heart, and spleen meridians. Angelica contains main ingredients such as ferulic acid, succinic acid, and stigmasterol, which have the effects of nourishing blood, regulating menstruation and relieving pain, and moistening the intestines and relieving constipation.

[0019] Polygala: Polygala is a traditional Chinese medicine that can be used as both medicine and food. It tastes bitter and pungent, and is warm in nature. It enters the heart, kidney, and lung meridians. Polygala contains polygala saponins, polygala alcohol, α-spinasterol, and other main ingredients, which have the effects of calming the mind, improving intelligence, removing phlegm, and reducing swelling.

[0020] Morinda officinalis: Morinda officinalis is a Chinese medicinal material that is both a medicine and a food. It tastes sweet and spicy, is slightly warm in nature, and enters the kidney meridian. Morinda officinalis contains methyl isorubiacein, rhubarb methyl ether, crystal orchid glycoside, tetraacetyl styracoside, palmitic acid, cardiac glycosides, flavonoids, steroidal triterpenes, amino acids, organic acids, nonadecane and other ingredients, which can replenish kidney yang, strengthen tendons and bones, and eliminate rheumatism.

[0021] Wolfberry: Wolfberry is a traditional Chinese medicine that can be used as both medicine and food. It is sweet and neutral in nature. It enters the liver and kidney meridians. Wolfberry contains betaine, wolfberry polysaccharide, carotene, zeaxanthin, niacin and other ingredients. Among them, betaine protects the liver and reduces the burden on the liver. It has the effect of nourishing the liver and kidneys and improving vision.

[0022] Sichuan pepper: Sichuan pepper is a traditional Chinese medicine that can be used as both medicine and food. It is spicy and warm in nature. It enters the spleen, stomach, and kidney meridians. Sichuan pepper contains ingredients such as sanshool, coumarin, and green pepper, which have the effects of increasing appetite, antibacterial and insecticidal, and dispelling cold and relieving pain.

[0023] Chinese Yam: Chinese Yam is a Chinese herbal medicine that can be used as both medicine and food. It is sweet and mild in taste, and can nourish the spleen, lung, and kidney meridians. Chinese Yam contains ingredients such as yam, yam alkaloids, acerol II, stigmasterol, cholesterol, yam alkaloids hydrochloride, ergosterol, and quinic acid, which have the effects of nourishing qi and yin, nourishing the spleen, lungs, and kidneys, and stopping leukorrhea.

[0024] Cuscuta: Cuscuta is a traditional Chinese medicine that can be used as both medicine and food. It tastes spicy and sweet, and is neutral in nature. It enters the liver, spleen, and kidney meridians. Cuscuta contains flavonoids such as apigenin, quercetin, and quercetin, and polysaccharides such as mannose, rhamnose, galactose, and glucose. It has the effects of nourishing the liver and kidneys, consolidating semen and reducing urine, calming the fetus, and improving eyesight.

[0025] Eucommia: Eucommia is a traditional Chinese medicine that can be used as both medicine and food. It tastes sweet, slightly spicy, and warm in nature. It enters the liver and kidney meridians. Eucommia contains ingredients such as eucommia lignans, aucubin, geniposide, geniposide acid, kaempferol, and eucommia seed glucoside. Among them, eucommia lignans protect the kidneys from damage. It has the effect of nourishing the liver and kidneys and strengthening the tendons and bones.

[0026] A preparation method of a yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons, the preparation method comprises the following steps:

[0027] (1) Preparation of medicinal materials: weigh ginseng, Poria, Chinese yam, Astragalus, Atractylodes, Zanthoxylum, Eucommia, Morinda officinalis, Rehmannia root, Radix Rehmanniae, Radix Angelicae Sinensis, Cuscuta and Polygala, mix, grind, sieve, stir-fry at low temperature, and bag to obtain Chinese medicine powder bags; weigh chrysanthemum, wolfberry and mulberry and bag to obtain dry medicine bags;

[0028] (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 800-1000 mL of clean water, boil over high heat and then simmer over low heat for 8-20 min. Remove the dry medicine bag and Chinese medicine powder bag, divide the medicine liquid into portions, and obtain the Yang-tonifying and tendon-strengthening decoction.

[0029] According to the above method, the present invention grinds the Chinese medicinal materials into powder and stir-fries them at low temperature to promote the rapid precipitation of effective ingredients in the Chinese herbal medicine during the decoction process, reduce the decoction time and number of decoctions, and reduce the volatilization of flavonoid components in the Chinese medicinal materials with water and the inactivation of polysaccharide components caused by long-term high-temperature decoction.

[0030] Preferably, in the above technical solution, the sieving is to sieve through a 80-100 mesh sieve, and the sieved powder is taken.

[0031] According to the above technical solution, the purpose of setting the particle size of Chinese medicinal materials at 80-100 mesh sieve is that Chinese medicinal materials that are too large and fried at low temperature for 3-5 minutes are difficult to cook, resulting in a reduction in the effective ingredients of the decoction obtained within the preset time. The 80-100 mesh sieve screens out Chinese medicinal particles with a particle size less than 0.18mm, which can reduce the decoction time without reducing the effective ingredients.

[0032] Preferably, in the above technical solution, the specific step of low-temperature frying is frying at a temperature of 45-55°C for 3-5 minutes.

[0033] According to the above technical solution, Chinese medicine particles smaller than 0.18 mm are fried at 45-55°C for 3-5 minutes to destroy the covalent bonds between polymers inside the Chinese medicine cells without destroying the structure of polysaccharides, which helps to increase the release of flavonoids and polysaccharide components of the Chinese medicine into the medicine during the decoction process, thereby increasing the effective ingredients in the medicine.

[0034] A preparation method of a yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons, the preparation method comprises the following steps:

[0035] (1) Preparation of medicinal materials: weigh ginseng, Poria, Chinese yam, Astragalus, Atractylodes, Zanthoxylum, Eucommia, Morinda officinalis, Rehmannia root, Radix Rehmanniae, Radix Angelicae Sinensis, Cuscuta and Polygala, mix, grind, sieve, stir-fry at low temperature, and bag to obtain Chinese medicine powder bags; weigh chrysanthemum, wolfberry and mulberry and bag to obtain dry medicine bags;

[0036] (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 800-1000 mL of clean water, boil over high heat and then simmer over low heat for 8-20 min, remove the dry medicine bag and Chinese medicine powder bag, and take the medicine liquid;

[0037] (3) Concentrating: Concentrating the drug solution by low-temperature evaporation to obtain a concentrated solution;

[0038] (4) Pill making: The concentrated liquid and the filler are mixed and kneaded to obtain the Yang-boosting and tendon-strengthening pills.

[0039] Preferably, in the above technical solution, the sieving is through a 80-100 mesh sieve, and the sieved powder is taken.

[0040] Preferably, in the above technical solution, the specific step of low-temperature frying is frying at a temperature of 45-55°C for 3-5 minutes.

[0041] Preferably, in the above technical solution, in the concentration step, the low-temperature concentration is specifically: placing the drug solution in a heating container, heating the heating container at a constant temperature of 55° C., and obtaining a concentrated solution when the volume of the drug solution is reduced to 1 / 3-1 / 4 of the original volume.

[0042] Compared with the prior art, the present invention has the following beneficial effects:

[0043] (1) The yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidney and tendons and bones of the present invention is mainly composed of monarch drugs, minister drugs assisting the monarch drugs, and adjuvant drugs treating concurrent symptoms, so that the drugs can harmonize the drugs. The pharmacology of the yang-tonifying and tendon-strengthening composition for treating kidney deficiency and low back pain is as follows: the monarch drugs chrysanthemum, Morinda officinalis and Lycium barbarum work together to remove internal heat, calm liver yang, invigorate kidney yang, invigorate essence and qi, remove fatigue, and strengthen tendons and bones; the minister drugs ginseng, astragalus and yam work together with the adjuvant drug angelica to work together to invigorate qi, benefit qi and promote qi circulation in the body, and help the main drug to treat qi deficiency and decline, sinking of middle qi, which causes insufficient qi and blood circulation and blocked meridians, thereby relieving symptoms of soreness and weakness in the waist and knees and fatigue; the minister drugs Poria cocos and Atractylodes macrocephala work together with the adjuvant drug Rehmannia glutinosa to strengthen the spleen, promote the production of body fluid, promote urination and eliminate dampness , helping the main drug to remove internal heat and calm liver yang, thereby relieving the symptoms of kidney yin deficiency and internal heat; the assistant drugs ginseng, polygala and dodder seeds, cooperate with the adjuvant Rehmannia glutinosa to help the main drug to nourish the liver and kidney, nourish yin and spleen, calm the mind and improve intelligence, thereby relieving the symptoms of kidney deficiency and fatigue due to yin deficiency; the assistant drugs astragalus, prickly ash and mulberry, cooperate with the adjuvant Rehmannia glutinosa and raw Rehmannia glutinosa, help the main drug to produce blood, nourish essence, fill marrow, strengthen tendons and bones, thereby treating the symptoms of liver and kidney deficiency and weak tendons and bones; the auxiliary drug Eucommia ulmoides leads the drugs to the liver, kidney and waist and back, improving the efficacy of the drugs. The 16 Chinese medicinal materials in the formula are all Chinese medicinal materials that are both medicinal and edible.

[0044] (2) Lycium barbarum polysaccharides and flavonoids from Morinda officinalis stimulate the gonad axis in the pituitary gland to tonify the kidney. Morinda officinalis polysaccharides and chrysanthemum glycosides can promote the expression of osteocalcin and osteoprotegerin, promote the synthesis of osteoblasts and inhibit the growth of osteoclasts, promote mineralization, increase bone density, and improve the microstructure of trabeculae, thereby achieving the effects of tonifying the spleen and kidneys and strengthening the tendons and bones. The polysaccharides and saponins from Astragalus and mulberry promote and protect the regeneration and growth of hematopoietic cells. DETAILED DESCRIPTION

[0045] The terms first, second, third, etc. are used herein to describe various parts, components, regions, layers, and / or segments, but these parts, components, regions, layers, and / or segments should not be limited by these terms. These terms are only used to distinguish a certain part, component, region, layer, and / or segment from another part, component, region, layer, and / or segment. Therefore, without departing from the scope of the present invention, the first part, component, region, layer, and / or segment described below may also be described as the second part, component, region, layer, and / or segment.

[0046] The terms used herein are only for describing specific embodiments and are not intended to limit the present invention. Unless the context clearly indicates otherwise, the singular form used herein is also intended to include the plural form. It should also be understood that the term "comprising" specifically refers to a certain characteristic, field, integer, step, action, element and / or component, but does not exclude the existence or addition of other characteristics, fields, integers, steps, actions, elements, components and / or groups.

[0047] Although not otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as those commonly understood by those skilled in the art. Terms with definitions in dictionaries should be interpreted as having the same meaning as those disclosed in the relevant technical literature and this article, and should not be interpreted in an idealized or overly formal sense.

[0048] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0049] Example 1

[0050] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 48g of chrysanthemum, 3g of ginseng, 10g of poria, 4g of yam, 10g of astragalus, 6g of atractylodes, 3g of zanthoxylum bungeanum, 10g of mulberry, 16g of wolfberry, 8g of eucommia, 16g of morinda officinalis, 8g of dodder seed, 16g of prepared rehmannia, 6g of raw rehmannia, 16g of angelica and 4g of polygala.

[0051] A method for preparing a yang-tonifying and tendon-strengthening composition for strengthening the spleen, kidneys, tendons and bones, the method comprising the following steps:

[0052] (1) Preparation of medicinal materials: According to the weight of the raw materials of the above-mentioned yang-tonifying and tendon-strengthening composition, ginseng, poria, yam, astragalus, atractylodes, zanthoxylum, eucommia, Morinda officinalis, prepared rehmannia root, raw rehmannia root, angelica, dodder seed and polygala root are weighed respectively, mixed and ground into powder, the powder is passed through an 80-mesh sieve, and the unsieved powder is subjected to the grinding step repeatedly until all the powder is sieved, and then low-temperature frying is carried out at 50° C. for 4 minutes, and the fried powder is bagged to obtain a Chinese medicine powder bag;

[0053] Weigh chrysanthemum, wolfberry and mulberry and put them into bags to obtain dry medicine bags;

[0054] (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 800 mL of clean water, boil over high heat and then simmer over low heat for 14 minutes. Remove the dry medicine bag and Chinese medicine powder bag and divide the medicine liquid into 200-250 mL / bag of yang-tonifying and tendon-strengthening decoction.

[0055] Example 2

[0056] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 24g of chrysanthemum, 1.5g of ginseng, 5g of poria, 2g of yam, 5g of astragalus, 3g of atractylodes, 1.5g of zanthoxylum bungeanum, 5g of mulberry, 8g of wolfberry, 4g of eucommia, 8g of morinda officinalis, 4g of dodder seed, 8g of prepared rehmannia, 3g of raw rehmannia, 8g of angelica and 2g of polygala.

[0057] A method for preparing a yang-tonifying and tendon-strengthening composition for strengthening the spleen, kidneys, tendons and bones, the method comprising the following steps:

[0058] (1) Preparation of medicinal materials: according to the weight of the raw materials of the above-mentioned yang-tonifying and tendon-strengthening composition, respectively weigh ginseng, poria, yam, astragalus, atractylodes, zanthoxylum, eucommia, Morinda officinalis, prepared rehmannia root, raw rehmannia root, angelica, dodder seed and polygala tenuifolia, mix and grind into powder, pass the powder through a 100-mesh sieve, repeat the grinding step for the unsieved powder, and stir-fry at 55° C. for 5 min after all the powder is sieved, and bag the stir-fried powder to obtain a Chinese medicine powder bag;

[0059] Weigh chrysanthemum, wolfberry and mulberry and put them into bags to obtain dry medicine bags;

[0060] (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 900 mL of clean water, boil over high heat and then simmer over low heat for 16 minutes. Remove the dry medicine bag and Chinese medicine powder bag and divide the medicine liquid into 200-250 mL / bag of yang-tonifying and tendon-strengthening decoction.

[0061] Example 3

[0062] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 72g of chrysanthemum, 4.5g of ginseng, 15g of poria, 6g of yam, 15g of astragalus, 9g of atractylodes, 4.5g of zanthoxylum bungeanum, 15g of mulberry, 24g of wolfberry, 12g of eucommia, 24g of morinda officinalis, 12g of dodder seed, 24g of prepared rehmannia, 9g of raw rehmannia, 24g of angelica and 6g of polygala.

[0063] Prepare the Yang-boosting and tendon-strengthening decoction according to the method of Example 1.

[0064] Example 4

[0065] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 20g of chrysanthemum, 1g of ginseng, 4g of poria, 1.5g of yam, 4g of astragalus, 2g of atractylodes, 1g of prickly ash, 4g of mulberry, 4g of wolfberry, 3g of eucommia, 4g of morinda officinalis, 3g of dodder seed, 4g of prepared rehmannia, 2g of raw rehmannia, 4g of angelica and 1.5g of polygala.

[0066] Prepare the Yang-boosting and tendon-strengthening decoction according to the method of Example 1.

[0067] Example 5

[0068] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 80g of chrysanthemum, 6g of ginseng, 4g of poria, 8g of yam, 18g of astragalus, 10g of atractylodes, 6g of zanthoxylum, 18g of mulberry, 28g of wolfberry, 15g of eucommia, 28g of morinda officinalis, 15g of dodder seed, 28g of prepared rehmannia, 10g of raw rehmannia, 28g of angelica and 8g of polygala.

[0069] Prepare the Yang-boosting and tendon-strengthening decoction according to the method of Example 1.

[0070] Example 6

[0071] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 48g of chrysanthemum, 3g of ginseng, 10g of poria, 4g of yam, 10g of astragalus, 6g of atractylodes, 3g of zanthoxylum bungeanum, 10g of mulberry, 16g of wolfberry, 8g of eucommia, 16g of morinda officinalis, 8g of dodder seed, 16g of prepared rehmannia, 6g of raw rehmannia, 16g of angelica and 4g of polygala.

[0072] Prepare the Yang-boosting and tendon-strengthening decoction according to the method of Example 1.

[0073] Example 7

[0074] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 48g of chrysanthemum, 3g of ginseng, 10g of poria, 4g of yam, 10g of astragalus, 6g of atractylodes, 3g of zanthoxylum bungeanum, 10g of mulberry, 16g of wolfberry, 8g of eucommia, 16g of morinda officinalis, 8g of dodder seed, 16g of prepared rehmannia, 6g of raw rehmannia, 16g of angelica and 4g of polygala.

[0075] A preparation method of a yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons, the preparation method comprises the following steps:

[0076] (1) Preparation of medicinal materials: According to the weight of the raw materials of the above-mentioned yang-tonifying and tendon-strengthening composition, ginseng, poria, yam, astragalus, atractylodes, zanthoxylum, eucommia, Morinda officinalis, prepared rehmannia root, raw rehmannia root, angelica, dodder seed and polygala root are weighed respectively, mixed and ground into powder, the powder is passed through an 80-mesh sieve, and the unsieved powder is subjected to the grinding step repeatedly until all the powder is sieved, and then low-temperature frying is carried out at 50° C. for 4 minutes, and the fried powder is bagged to obtain a Chinese medicine powder bag;

[0077] Weigh chrysanthemum, wolfberry and mulberry and put them into bags to obtain dry medicine bags;

[0078] (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 800 mL of clean water, boil over high heat and then simmer over low heat for 14 min, remove the dry medicine bag and Chinese medicine powder bag, and take the medicine liquid;

[0079] (3) Concentration: Place the drug solution in a heating container and heat the container at a constant temperature of 55°C until the volume of the drug solution is reduced to 1 / 4 of the original volume, thereby obtaining a concentrated solution;

[0080] (4) Pill making: Mix the concentrated solution and knead it to obtain the Yang-boosting and tendon-strengthening pills.

[0081] Example 8

[0082] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 24g of chrysanthemum, 1.5g of ginseng, 5g of poria, 2g of yam, 5g of astragalus, 3g of atractylodes, 1.5g of zanthoxylum bungeanum, 5g of mulberry, 8g of wolfberry, 4g of eucommia, 8g of morinda officinalis, 4g of dodder seed, 8g of prepared rehmannia, 3g of raw rehmannia, 8g of angelica and 2g of polygala.

[0083] A preparation method of a yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons, the preparation method comprises the following steps:

[0084] (1) Preparation of medicinal materials: according to the weight of the raw materials of the above-mentioned yang-tonifying and tendon-strengthening composition, respectively weigh ginseng, poria, yam, astragalus, atractylodes, zanthoxylum, eucommia, Morinda officinalis, prepared rehmannia root, raw rehmannia root, angelica, dodder seed and polygala tenuifolia, mix and grind into powder, pass the powder through a 100-mesh sieve, repeat the grinding step for the unsieved powder, and stir-fry at 55° C. for 3 min after all the powder is sieved, and bag the stir-fried powder to obtain a Chinese medicine powder bag;

[0085] Weigh chrysanthemum, wolfberry and mulberry and put them into bags to obtain dry medicine bags;

[0086] (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 1000 mL of clean water, boil over high heat and then simmer over low heat for 18 min, remove the dry medicine bag and Chinese medicine powder bag, and take the medicine liquid;

[0087] (3) Concentration: Place the drug solution in a heating container and heat the container at a constant temperature of 55°C until the volume of the drug solution is reduced to 1 / 3 of the original volume, thereby obtaining a concentrated solution;

[0088] (4) Pill making: The concentrated liquid and the filler are mixed and kneaded to obtain the Yang-boosting and tendon-strengthening pills.

[0089] Example 9

[0090] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 72g of chrysanthemum, 4.5g of ginseng, 15g of poria, 6g of yam, 15g of astragalus, 9g of atractylodes, 4.5g of zanthoxylum bungeanum, 15g of mulberry, 24g of wolfberry, 12g of eucommia, 24g of morinda officinalis, 12g of dodder seed, 24g of prepared rehmannia, 9g of raw rehmannia, 24g of angelica and 6g of polygala.

[0091] Example 10

[0092] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 20g of chrysanthemum, 1g of ginseng, 4g of poria, 1.5g of yam, 4g of astragalus, 2g of atractylodes, 1g of prickly ash, 4g of mulberry, 4g of wolfberry, 3g of eucommia, 4g of morinda officinalis, 3g of dodder seed, 4g of prepared rehmannia, 2g of raw rehmannia, 4g of angelica and 1.5g of polygala.

[0093] Embodiment 11

[0094] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 80g of chrysanthemum, 6g of ginseng, 4g of poria, 8g of yam, 18g of astragalus, 10g of atractylodes, 6g of zanthoxylum, 18g of mulberry, 28g of wolfberry, 15g of eucommia, 28g of morinda officinalis, 15g of dodder seed, 28g of prepared rehmannia, 10g of raw rehmannia, 28g of angelica and 8g of polygala.

[0095] Example 12

[0096] A yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons, the raw materials of the yang-tonifying and tendon-strengthening composition include 48g chrysanthemum, 3g ginseng, 10g poria, 4g yam, 10g astragalus, 6g atractylodes, 3g prickly ash, 10g mulberry, 16g wolfberry, 8g eucommia, 16g Morinda officinalis, 8g dodder seed, 16g prepared rehmannia, 6g raw rehmannia, 16g angelica and 4g polygala. The decoction will be better than the honey pill, but it can also play a good therapeutic effect.

[0097] Comparative Example 1

[0098] The method is basically the same as Example 1, except that the preparation method adopts a direct decoction method. A method for preparing a yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidneys and tendons, the method is as follows:

[0099] (1) Preparation of medicinal materials: weigh ginseng, Poria cocos, Chinese yam, Astragalus, Atractylodes macrocephala, Zanthoxylum bungeanum, Eucommia ulmoides, Morinda officinalis, Rehmannia root, Radix Rehmanniae glutinosae, Angelica sinensis, Cuscuta chinensis, Polygala tenuifolia, Chrysanthemum, Lycium barbarum, and Mulberry;

[0100] (2) Decoction: Place the prepared Chinese medicinal materials in 500 mL of water, boil over high heat and then simmer for 20 min, filter and separate the medicinal liquid and the residue, add 500 mL of water to the residue, boil over high heat and then simmer for 20 min, filter and separate the medicinal liquid and the residue, mix the two medicinal liquids and package them to obtain a yang-boosting and tendon-strengthening decoction.

[0101] Comparative Example 2

[0102] The method is basically the same as Example 1, except that the preparation method adopts a traditional method. A method for preparing a yang-tonifying and tendon-strengthening composition for strengthening the spleen, kidneys, tendons and bones, the method comprising the following steps:

[0103] (1) Preparation of medicinal materials: according to the weight of the raw materials of the above-mentioned yang-tonifying and tendon-strengthening composition, weigh ginseng, poria, yam, astragalus, atractylodes, zanthoxylum, eucommia, Morinda officinalis, prepared rehmannia root, raw rehmannia root, angelica, dodder seed and polygala tenuifolia respectively, mix, grind, sieve and bag to obtain Chinese medicine powder bags; weigh chrysanthemum, wolfberry and mulberry and pack them separately to obtain dry medicine bags;

[0104] (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 800-1000 mL of clean water, boil over high heat and then simmer over low heat for 8-20 min. Remove the dry medicine bag and Chinese medicine powder bag, divide the medicine liquid into portions, and obtain the Yang-tonifying and tendon-strengthening decoction.

[0105] Comparative Example 3

[0106] The invention is basically the same as Example 1, except that the raw materials are different. The raw materials include 48g chrysanthemum, 3g ginseng, 10g Poria, 4g yam, 10g Astragalus, 6g Atractylodes, 3g Zanthoxylum, 10g mulberry, 8g Eucommia, 8g Cuscuta, 16g Rehmannia root, 6g Rehmannia root, 16g Angelica and 4g Polygala.

[0107] Comparative Example 4

[0108] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 48g of chrysanthemum, 3g of ginseng, 10g of poria, 4g of yam, 10g of astragalus, 6g of atractylodes, 3g of zanthoxylum bungeanum, 10g of mulberry, 16g of wolfberry, 8g of eucommia, 16g of morinda officinalis, 8g of dodder seed, 16g of prepared rehmannia, 6g of raw rehmannia, 16g of angelica and 4g of polygala.

[0109] Comparative Example 5

[0110] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 48g chamomile, 3g ginseng, 10g poria, 4g yam, 10g astragalus, 6g atractylodes, 3g zanthoxylum, 10g mulberry, 16g wolfberry, 8g eucommia, 16g morinda officinalis, 8g dodder seed, 16g prepared rehmannia, 6g raw rehmannia, 16g angelica and 4g polygala.

[0111] Comparative Example 6

[0112] A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, wherein the raw materials of the yang-tonifying and tendon-strengthening composition include 48g of chrysanthemum, 3g of ginseng, 10g of poria, 4g of yam, 6g of atractylodes, 16g of wolfberry, 8g of eucommia, 8g of dodder seed, 16g of rehmannia root and 16g of angelica.

[0113] Comparative Example 7

[0114] It is basically the same as Example 1, except that the Morinda officinalis, mulberry, and Polygala tenuifolia are replaced by mistletoe, antler glue, and licorice, respectively, and the raw materials of the yang-tonifying and tendon-strengthening composition include 48g chrysanthemum, 3g ginseng, 10g Poria, 4g yam, 10g Astragalus, 6g Atractylodes, 3g Zanthoxylum, 10g antler glue, 16g wolfberry, 8g Eucommia, 16g mistletoe, 8g Cuscuta australis, 16g Rehmannia glutinosa, 6g Rehmannia glutinosa, 16g Angelica sinensis, and 4g licorice.

[0115] Comparative Example 8

[0116] The method is basically the same as Example 7, except that the preparation method of the Buyang Zhuangjin Pill is different. The preparation method steps are as follows:

[0117] (1) Preparation of medicinal materials: according to the weight of the raw materials of the above-mentioned yang-tonifying and tendon-strengthening composition, respectively weigh ginseng, poria, yam, astragalus, atractylodes, zanthoxylum, eucommia, Morinda officinalis, prepared rehmannia root, raw rehmannia root, angelica, dodder seed, polygala tenuifolia, chrysanthemum, wolfberry and mulberry, mix and grind into powder, pass the powder through a 300-mesh sieve, repeat the grinding step for the unsieved powder until all the powder is obtained, and set aside the sieved powder for later use;

[0118] (2) Pill making: Add honey to the powder, knead and mix well to make round pellets of uniform size to obtain Yang-boosting and tendon-strengthening pills.

[0119] Comparative Example 9

[0120] It is basically the same as Comparative Example 8, except that the preparation method of the Buyang Zhuangjin Pill is different. The preparation method is as follows:

[0121] (1) Preparation of medicinal materials: According to the weight of the raw materials of the above-mentioned yang-tonifying and tendon-strengthening composition, ginseng, poria, yam, astragalus, atractylodes, zanthoxylum, eucommia, Morinda officinalis, prepared rehmannia root, raw rehmannia root, angelica, dodder seed, polygala tenuifolia, chrysanthemum, wolfberry and mulberry are weighed respectively, mixed and ground into powder, the powder is passed through a 300-mesh sieve, and the unsieved powder is subjected to the grinding step repeatedly until all the powder is sieved, and then low-temperature frying is carried out at 50° C. for 4 min, and the fried powder is set aside for later use;

[0122] (2) Pill making: Add honey to the powder, knead and mix well to make round pellets of uniform size to obtain Yang-boosting and tendon-strengthening pills.

[0123] Animal experiments

[0124] The principle of establishing the model is to use estradiol benzoate to induce suppression of the hypothalamus-pituitary-gonadal axis in mice, causing the mice to show symptoms such as weakened activity and decreased resistance to fatigue, thereby constructing a kidney deficiency model.

[0125] Create the model: First, prepare a 0.1 mg / mL estradiol benzoate solution: directly dissolve and mix 1 mL of estradiol benzoate injection with 100 mL of tea oil for injection in a proportional manner to obtain 0.1 mg / mL estradiol benzoate; secondly, create a kidney deficiency model: inject 0.4 mg / mL estradiol benzoate into mice intravenously at 9:00 am every day for 15 consecutive days to create a kidney deficiency model.

[0126] Characteristics of a successful model: (1) dull eyes, prolonged lying still, and decreased spontaneous activity; (2) elevated creatinine and urea levels.

[0127] Finally, a total of 63 mice with kidney deficiency model were successfully constructed. The 63 mice with kidney deficiency model were divided into 11 groups, marked, and blood was drawn on an empty stomach to detect and record the creatinine and urea levels of each mouse. The mice were gavaged with the same amount of the yang-tonifying and tendon-strengthening composition prepared in each group in the morning and evening, respectively. The experiment was continued for 15 days. On the 16th day of the experiment, blood was drawn on an empty stomach in the morning to detect and record the creatinine and urea levels of each mouse. The average values ​​of mouse activity scores, creatinine and urea before and after treatment were calculated and are shown in Table 1 below.

[0128] The activity scoring rules are as follows:

[0129] 1 point: dull eyes, lying still for a long time, and 0 independent movements within 3 hours;

[0130] 2 points: lying down and being lazy, with 1-3 independent activities within 3 hours;

[0131] 3 points: less sleeping, more running, 4-6 independent activities within 3 hours;

[0132] 4 points: Not lying down, standing still or running, and the number of independent activities within 3 hours is 7-9 times.

[0133] Table 1 Activity scores, creatinine (mg / L) and urea (mg / L) of mice in each group before and after treatment

[0134]

[0135] As shown in Table 1, the creatinine and urea indexes of the model mice were significantly increased, and the activity scores were significantly decreased before treatment, indicating that the kidney function was significantly damaged, and kidney deficiency affected the activity of the mice, and the model mice were successfully established; and after treatment, the creatinine and urea of ​​some mice returned to normal, and the activity evaluation also increased, further indicating that the combination of the components of the yang-boosting and tendon-strengthening composition is more effective in treating renal function damage in model mice than lacking drugs or replacing drugs.

[0136] 18 volunteers with low back pain due to kidney deficiency were recruited. The requirements for the recruitment of volunteers with low back pain due to kidney deficiency were as follows: the volunteers in the blank control group were given unlabeled glucose oral solution once a day; the volunteers in the Example 1 group were given the Buyang Zhuangjin Drink prepared in Example 1 twice a day after meals; the volunteers in the Example 7 group were given the Buyang Zhuangjin Pills prepared by the method and formula of Example 7 twice a day after meals. The medication period was 1 month.

[0137] Blood samples were collected from volunteers before and after treatment to test creatinine concentration, and creatinine clearance was calculated according to the creatinine clearance formula, where the creatinine clearance formula is: male creatinine clearance (mL / min) = {(140-age) * body weight in kg} / (0.814 * creatinine concentration in μmol / L), female creatinine clearance (mL / min) = male creatinine clearance * 0.85. Note: The reference range of female creatinine concentration is 45-84 μmol / L, the reference range of male creatinine concentration is 53-106 μmol / L, and the reference range of creatinine clearance is 80-120 mL / min.

[0138] Table 2 Creatinine concentration and creatinine clearance rate of volunteers in each group before and after treatment

[0139]

[0140] As can be seen from Table 2, the creatinine clearance of volunteers in the blank control group without medication before and after treatment was lower than the normal range, and the fluctuation range before and after treatment was not large.

[0141] According to Table 2 above, the creatinine concentration and creatinine clearance rate of the blank control group, Example 1 group and Example 7 group before and after treatment were calculated: creatinine concentration = total creatinine of this group / 6, creatinine clearance rate = total creatinine clearance rate of this group / 6. The results are shown in Table 3.

[0142] Table 3 Average creatinine and creatinine clearance of volunteers in each group before and after treatment

[0143]

[0144] Volunteer case presentation: Huang Moujie, 47 years old, has a history of drinking and joint pain on rainy days. Before treatment, he had pain in the lower back, decreased libido, oliguria, difficulty falling asleep at night, less sleep, faster heartbeat when waking up in the morning, and more irritable mood; weight 81.8kg, creatinine 197μmol / L is higher than the normal range, and creatinine clearance rate 47.44mL / min is lower than the normal range. Take a Buyang Zhuangjin Pill after lunch and dinner, and the medication time is from July 10 to August 8. After treatment, the symptoms of taking the medicine for about a week increased sleep time, the pain in the waist was alleviated and gradually disappeared, the symptoms of faster heartbeat when waking up in the morning disappeared, the need for drinking water during the day increased, and the number and amount of urination increased.

[0145] Liu Mouxia, 46 years old, had diffuse pain in the waist, shoulders and neck during work before treatment, sore hands and feet, poor sleep quality, easy to wake up in the middle of the night and difficult to fall asleep again, irritability; weight 56.7kg, creatinine 141μmol / L higher than the normal range, creatinine clearance 39.47mL / min lower than the normal range. Take a dose of Buyang Zhuangjin Pills after lunch and dinner, and take the medicine from July 12 to August 10. After treatment, there is no sudden awakening in the middle of the night when taking the medicine, the sleep quality is improved, the pain in the waist, shoulders and neck is reduced and gradually disappears, and the symptoms of muscle weakness disappear.

[0146] The present invention can be implemented in various ways and is not limited to the embodiments described. A person skilled in the art can understand that the present invention can be implemented in other specific ways without changing the technical concept or essential features of the present invention. Therefore, it should be understood that the embodiments described above are exemplary and are not intended to limit the present invention.

Claims

1. A yang-tonifying and tendon-strengthening composition for invigorating the spleen, kidneys and tendons, characterized in that: By weight, the raw materials of the yang-tonifying and tendon-strengthening composition include 20-80g chrysanthemum, 1-6g ginseng, 4-18g poria, 1.5-8g yam, 4-18g astragalus, 2-10g atractylodes, 1-6g zanthoxylum, 4-18g mulberry, 4-28g wolfberry, 3-15g eucommia, 4-28g morinda officinalis, 3-15g dodder seed, 4-28g rehmannia root, 2-10g raw rehmannia root, 4-28g angelica root and 1.5-8g polygala.

2. The yang-tonifying and tendon-strengthening composition for strengthening the spleen, kidneys, tendons and bones according to claim 1, characterized in that: By weight, the raw materials of the yang-tonifying and tendon-strengthening composition include 24-72g chrysanthemum, 1.5-4.5g ginseng, 5-15g poria, 2-6g yam, 5-15g astragalus, 3-9g atractylodes, 1.5-4.5g zanthoxylum, 5-15g mulberry, 8-24g wolfberry, 4-12g eucommia, 8-24g morinda officinalis, 4-12g dodder seed, 8-24g rehmannia root, 3-9g rehmannia root, 8-24g angelica root and 2-6g polygala.

3. The yang-tonifying and tendon-strengthening composition for strengthening the spleen, kidneys and bones according to claim 2, characterized in that: By weight, the raw materials of the yang-tonifying and tendon-strengthening composition include 48g chrysanthemum, 3g ginseng, 10g poria, 4g yam, 10g astragalus, 6g atractylodes, 3g zanthoxylum, 10g mulberry, 16g wolfberry, 8g eucommia, 16g Morinda officinalis, 8g dodder seed, 16g prepared rehmannia, 6g raw rehmannia, 16g angelica and 4g polygala.

4. A method for preparing a yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidneys and tendons, characterized in that: The preparation method steps are as follows: (1) Preparation of medicinal materials: weigh ginseng, Poria, Chinese yam, Astragalus, Atractylodes, Zanthoxylum, Eucommia, Morinda officinalis, Rehmannia root, Radix Rehmanniae, Radix Angelicae Sinensis, Cuscuta and Polygala, mix, grind, sieve, stir-fry at low temperature, and bag to obtain Chinese medicine powder bags; weigh chrysanthemum, wolfberry and mulberry and bag to obtain dry medicine bags; (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 800-1000 mL of clean water, boil over high heat and then simmer over low heat for 8-20 min. Remove the dry medicine bag and Chinese medicine powder bag, divide the medicine liquid into portions, and obtain the Yang-tonifying and tendon-strengthening decoction.

5. The method for preparing the yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons and bones according to claim 4, characterized in that: The sieving is to sieve through a 80-100 mesh sieve, and take the sieved powder.

6. The method for preparing the yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons according to claim 4, characterized in that: The specific step of low temperature frying is frying at a temperature of 45-55° C. for 3-5 minutes.

7. A method for preparing a yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidneys, tendons and bones, characterized in that: The preparation method steps are as follows: (1) Preparation of medicinal materials: weigh ginseng, Poria, Chinese yam, Astragalus, Atractylodes, Zanthoxylum, Eucommia, Morinda officinalis, Rehmannia root, Radix Rehmanniae, Radix Angelicae Sinensis, Cuscuta and Polygala, mix, grind, sieve, stir-fry at low temperature, and bag to obtain Chinese medicine powder bags; weigh chrysanthemum, wolfberry and mulberry and bag to obtain dry medicine bags; (2) Decoction: Soak the Chinese medicine powder bag and dry medicine bag in 800-1000 mL of clean water, boil over high heat and then simmer over low heat for 8-20 min, remove the dry medicine bag and Chinese medicine powder bag, and take the medicine liquid; (3) Concentrating: Concentrating the drug solution by low-temperature evaporation to obtain a concentrated solution; (4) Pill making: The concentrated liquid and the filler are mixed and kneaded to obtain the Yang-boosting and tendon-strengthening pills.

8. The method for preparing the yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons according to claim 7, characterized in that: The sieving is to sieve through a 80-100 mesh sieve, and take the sieved powder.

9. The method for preparing the yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons and bones according to claim 7, characterized in that: The specific step of low temperature frying is frying at a temperature of 45-55° C. for 3-5 minutes.

10. The method for preparing the yang-tonifying and tendon-strengthening composition for benefiting the spleen, kidney and tendons and bones according to claim 7, characterized in that: In the concentration step, the low-temperature concentration is specifically as follows: placing the drug solution in a heating container, heating the heating container at a constant temperature of 55° C., and obtaining a concentrated solution when the volume of the drug solution is reduced to 1 / 3-1 / 4 of the original volume.

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