The invention discloses a fructus-trichosanthis phlegm-resolving binds-disspitating cough-suppressing panting-calming instant granule. Fructus-trichosanthis and bulbus fritillariae thunbergii are employed as sovereign medicines, and fructus aurantii, radix platycodonis, pericarpium citri reticulatae, rhizoma pinelliae preparatum, poria, fried rhizoma atractylodis macrocephalae and raw radix glycyrrhizae are employed as auxiliary materials, and steps of extraction, concentration drying, preparation of a soft material, pelletization, drying, particle finishing, sterilization and packaging are performed, so that the instant granule is prepared. The instant granule has the efficacy of clearing heat and detoxifying, dispelling dampness and dissipating binds, moistening lung and resolving phlegm, is capable of effectively alleviating and eliminating asthma and various symptoms caused by asthma, also has substantial treatment effect on allergic bronchial asthma, asthmatic bronchitis and various asthma symptoms caused by other causes, is fast in effectiveness, short in treatment course and free of side effect, and has the effective rate of 100%.