5 results about "Xanthohumol" patented technology

The application discloses application of xanthohumol in preparation of a medicine for resisting Aeromonas hydrophila infection of aquatic animals, and the xanthohumol can inhibit the activity of aerolysin of the Aeromonas hydrophila at a sub-inhibitory concentration, has a significant inhibitory effect on cell toxicity mediated by the aerolysin of the Aeromonas hydrophila, and further constructs an animal model infected by the Aeromonas hydrophila, and finds that the treatment of the xanthohumol can significantly improve the survival rate of the infected animals. The xanthohumol is one of main components of Chinese medicine hop, belongs to isoprenyl flavonoids, has biological functions such as bacteriostasis, anticancer, antioxidation, antiviral and hypoglycemic, and has high safety, and is an ideal medicine raw material or feed additive for preventing and treating the Aeromonas hydrophila infection of the aquatic animals.

The present invention is a method of isolating and purifying a plant-derived biologically active substance (xanthohumol) from the plant material of hops and from the by-product formed in the process of extracting hops with supercritical carbon dioxide.

The invention belongs to the technical field of biological medicines, and particularly relates to application of xanthohumol in preparation of a medicine for relieving allergic rhinitis and asthma symptoms. By constructing an animal model and a cell model, results show that xanthohumol can be successfully absorbed and metabolized by a digestive tract to play a biological role, and OVA-induced allergic airway inflammatory response can be remarkably improved. Compared with a disease model group, the xanthohumol can reduce the proportion of inflammatory cells in peripheral blood and BALF of mice and improve the infiltration condition of eosinophilic granulocytes in lung tissues. In addition, xanthohumol can regulate Th cell balance and cell factor release in mouse lung tissue. The oxidative stress state represented by OVA-induced ROS level rise causes the release of dsDNA and the activation of AIM2 inflammasome-related protein to be an important mechanism for mediating allergic airway inflammatory reaction, and the expression can be obviously improved by xanthohumol, so that a potential target and an effective strategy are provided for clinical treatment in the future.

The invention provides a high-efficiency corrosion-inhibition post-CMP cleaning solution and a preparation method and application thereof. The high-efficiency corrosion-inhibition post-CMP cleaning solution comprises the following components in parts by weight: 1-10 parts of a flavonoid structure modified derivative; 1-10 parts of an organic base; 2-8 parts of a corrosion inhibitor; 20-30 parts of an organic solvent; and 45-70 parts of ultrapure water. The flavonoid structure modified derivative is one or more of quercetin 3-glucuronic acid, xanthohumol and 8-isopentenyl naringenin, and the flavonoid structure modified derivative is one or more of quercetin 3-glucuronic acid, xanthohumol and 8-isopentenyl naringenin; the organic alkali is alkaloid; and the corrosion inhibitor is monoterpene glycoside. The invention further discloses a preparation method and application of the efficient corrosion inhibition CMP post-cleaning fluid. The efficient corrosion-inhibition post-CMP cleaning solution has the characteristics of efficient corrosion inhibition and low residue, and can be widely applied to the fields of semiconductor manufacturing, microelectronics and photoelectrons.