52 results about "Bioactive substance" patented technology

The invention discloses an intelligent gradient extraction process and method for nutritional ingredients in yak bone marrow, and belongs to the technical field of bioactive substance extraction. The extraction method comprises the following four steps: gradient pressure supercritical degreasing, double-enzyme synergistic gradient enzymolysis, acid concentration gradient demineralization and temperature gradient gelatin extraction, and through the process coupling design of gradient pressure degreasing, buffer enzymolysis, graded acidolysis and membrane separation of gelatin, the high yield of the product in the previous stage is ensured; active structures of follow-up components are reserved to the greatest extent. Meanwhile, a sensing-decision-execution closed-loop system is constructed, real-time data sources such as NIR moisture sensing, online OPA detection and XRD in-situ analysis are integrated, technological parameters are dynamically adjusted through a multi-objective optimization algorithm, and global optimization of the yield, the purity and the energy consumption is achieved.

The invention relates to the technical field of preparation of marine bioactive substances and functional foods, in particular to oyster peptide and application thereof in preparation of products for improving alcoholic liver injury. According to the invention, oyster peptide raw materials rich in natural taurine are adopted, scientific formula design and natural plant alcohol effect dispelling and liver protecting components are adopted, and adverse reactions after drinking, such as hangover, fatigue and alcoholic liver injury, are effectively relieved; according to the oyster peptide tabletted candy formula with the functions of dispelling the effects of alcohol and protecting the liver, provided by the invention, functional components all meet design requirements through detection.

The invention discloses a method for impregnating coffee beans with fructose under the assistance of ultrasonic waves, and relates to the technical field of food processing, and the method is technically characterized by comprising the following steps: selecting Robursta coffee beans with the moisture content of 10-12%; mixing with a 5% fructose solution according to a solid-liquid ratio of 1: 4, treating for 5-20 minutes (preferably 5 minutes) under ultrasonic waves of 40 kHz and 120 W, and totally impregnating for 4 hours; performing forced air drying at 40 DEG C for 23h until the water content is 10- And baking at the temperature of 175 DEG C for 7-8 minutes. A honeycomb net structure is formed on the surface of the coffee beans through ultrasonic treatment, the total sugar content is remarkably increased to 54.65 mg / g, amino acid composition is affected, and bioactive substances such as polyphenol and flavone are increased. The score of the baked coffee beans is more than 72 (the score of the coffee beans is 74.92 after the coffee beans are subjected to ultrasonic treatment for 5 minutes) through an SCA cup test, and the coffee beans have caramel fragrance, nut fragrance and smoother mouth feel. The method is simple and convenient to operate, low in cost and capable of effectively improving the flavor quality of the Robursta coffee.

The invention provides a preparation method of a low-salt high-quality fermented seasoning by adopting nano dissolution catalysis and ultraviolet sterilization treatment. The preparation method is mainly characterized in that raw materials are subjected to ultra-fine pulverization treatment and non-thermal sterilization treatment, and bioactive substances derived from various plant original taste components are added. Specifically, won is subjected to superfine pulverization to the size of 20-400 nm, and non-thermal sterilization methods such as high-pressure treatment, pulsed electric field or low-temperature plasma and the like are repeated for 2-7 times. In addition, the addition amount of bioactive substances (polyphenols, dietary fibers, essential amino acids and the like) extracted from 15-35 vegetable litchis selected according to a specific standard is in a range of 0.2-4%. The salinity is reduced to 30-70% of that of an existing product, meanwhile, the flavor and freshness are kept, and the low-sodium fermented seasoning with the health-care functions of reducing sodium absorption, inhibiting blood pressure rise, promoting growth of beneficial bacteria in intestinal tracts and the like can be produced. The invention provides an innovative manufacturing method, which not only can meet the requirements of consumers on health, but also can provide high-quality fermented seasoning.

The low-pressure low-temperature extraction and separation device is characterized in that an extraction bin is fixedly installed at the bottom of a tank body, an interlayer cavity is formed between the inner wall and the outer wall of the tank body, a spiral cooling pipe is installed in the interlayer cavity, and the two ends of a refrigerating unit are communicated with the two ends of the interlayer cavity through a liquid inlet pipe and a liquid outlet pipe; the two split type transmission mechanisms are installed at the upper end and the lower end of the stirring rod respectively, cleaning gears are rotationally installed at the top and the bottom in the tank body, and the split type transmission mechanisms are engaged with or disengaged from the cleaning gears according to the temperature change in the tank body. The external spiral cooling pipe, low-temperature refrigeration and internal stirring are combined, so that the core temperature of a material is always maintained at a set low temperature, the activity of thermosensitive components is effectively protected, efficient dynamic extraction can be realized, a cleaning function is achieved, waste is avoided, extraction and preliminary separation are continuously performed in the same closed system, and the extraction efficiency is improved. And material transfer steps and pollution risks are reduced, and the process continuity is high.

The invention belongs to the technical field of biological medicines and bioactive peptides, and relates to a xanthine oxidase inhibitory peptide derived from goat milk protein and application thereof. The amino acid sequence of the xanthine oxidase inhibitory peptide is as shown in SEQ ID NO. 1. The xanthine oxidase inhibitory peptide can be used for preparing a product for inhibiting xanthine oxidase or a product for regulating and controlling the uric acid level in a human body. The XOD regulation active peptide provided by the invention is safe in source and clear in structure, can be applied to the field of functional food or nutrition intervention, and provides a safe and natural active substance basis for diet regulation of hyperuricemia and related metabolic diseases.

The utility model discloses freezing equipment for preparing bioactive substances, which relates to the technical field of freezing and comprises a storage cabinet, mounting racks which are uniformly distributed are mounted in the storage cabinet, positioning strips are fixedly mounted on two sides of each mounting rack, and the positioning strips are inserted into two sides in the storage cabinet in a sliding manner. Sliding rails are fixedly mounted in the two sides of the top face of the mounting frame, under the cooperation of the sliding rails and sliding sleeves, the storage table is controlled to be pushed and pulled on the mounting frame, the storage table is moved out of the storage cabinet, the bioactive substances are taken and placed on the storage table, and the problems that due to the fact that the storage table in the storage cabinet is deep, the bioactive substances are inconvenient to take and place, and the working efficiency is high are solved. According to the storage cabinet, the problems that in the prior art, the using effect is poor are solved, positioning strips installed on the two sides of an installation frame are matched with a fixing assembly to complete installation and fixing of the installation frame in the storage cabinet, under the cooperation of the positioning strips and the fixing assembly, the installation frame can be detached from the storage cabinet, and the interior of the storage cabinet is convenient to clean.

The application discloses Lactobacillus delbrueckii SWU-DLB2 and SWU-DLB3 and development and application thereof in functional fermented food, and belongs to the technical field of microbial fermentation. The Lactobacillus delbrueckii SWU-DLB2 and SWU-DLB3 have been preserved in the Guangdong Microbial Culture Collection Center on October 28, 2025, and the preservation numbers are GDMCC No: 67173 and GDMCC No: 67174 respectively. It is found through experiments that the fermentation of the two strains mentioned above in dairy products containing Zizyphus jujuba Mill. powder can significantly improve the content of bioactive substances, and the total phenol content, flavonoid content and antioxidant activity are all significantly improved. The Lactobacillus delbrueckii strain provided by the application is combined with a plant-based supplement and applied to a food model, a functional food with enhanced neuroprotective potential is developed, and the important role of microbial metabolism in the functionalization of food is highlighted.

The utility model discloses a kind of biological chemical product low-temperature concentration equipment, it is related to vacuum concentration tank field.The utility model includes vacuum concentration tank body, the outside of vacuum concentration tank body is equipped with heating assembly;The heating assembly includes installation shell, the inside spiral of installation shell is provided with draft tube, both ends of the draft tube are passed through installation shell and are formed with liquid inlet, liquid outlet;The middle part of the draft tube is communicated with several groups of branch pipes, the branch pipe is projected to installation shell outside, electric three-way valve is installed in the communication intersection of branch pipe and draft tube, the utility model is connected by the draft tube and branch pipe of heating assembly through "Y" shape structure, cooperate electric three-way valve accurate switching heat medium flow direction, realize partition temperature control, the structure solves the problem that traditional concentration tank heating area is more difficult to control, enhance local heat exchange by the setting of branch pipe, reduce the heating temperature of other area, avoid biological active material inactivation due to local overheating.

The application discloses camel milk hypouricemic peptides with a hypouricemic effect and application thereof, and the amino acid sequence of the camel milk hypouricemic peptides is QPWMQ. The camel milk hypouricemic peptides can significantly inhibit the activity of xanthine oxidase (XOD) and / or adenosine deaminase (ADA), reduce the uric acid concentration in the body, maintain the normal level of uric acid in blood, and prevent and treat hyperuricemia; and the application fully excavates small-molecule bioactive substances of camel milk, and improves the nutritional value and economic value of camel milk.

The invention belongs to the technical field of edible mushroom cultivation, and particularly relates to an edible mushroom culture medium and an edible mushroom cultivation method. The edible mushroom culture medium comprises the following components in parts by weight: 25-30 parts of a tribulus terrestris hard thorn enzymolysis product, 20-25 parts of magnetic wheat bran, 10-15 parts of cottonseed hull, 12-15 parts of corncob powder, 5-7 parts of soybean meal, 0.5-1 part of light calcium carbonate and 0.5-1 part of quick lime, and the water content is 65-70%. According to the method, the waste tribulus terrestris hard thorn residues are smashed and then subjected to composite enzymolysis treatment, a large amount of soluble saccharides are released, specific bioactive substances of the tribulus terrestris are reserved, the fertility of the matrix can be enhanced under the condition that sufficient lignin sources are provided, the metabolic activity of edible mushroom hyphae can be remarkably enhanced, and the yield of edible mushrooms is increased. The utilization rate of the edible fungi on nutrient substances in the culture medium is increased, meanwhile, waste utilization of the hard thorn residues of the tribulus terrestris can be achieved, resource waste is avoided, and sustainable development is achieved.

This invention relates to the field of medicinal wine technology, specifically to a medicinal wine made from Polygonatum odoratum and Polygonatum sibiricum, and its preparation method. The raw materials include baijiu (Chinese white liquor) and medicinal herbs, with a weight ratio of baijiu to medicinal herbs of 100:(1-5). The medicinal herbs, by weight, include: 10-15 parts Polygonatum odoratum, 20-30 parts Polygonatum sibiricum, 10-15 parts ginseng, 10-15 parts licorice root, 10-15 parts raspberry, 20-30 parts Cistanche deserticola, 20-30 parts Morinda officinalis, 30-50 parts Lycium barbarum, and 40-50 parts jujube. The specific method involves first pulverizing the medicinal herbs into powder, then processing the powder; then separating and purifying the processed medicinal herbs; finally, preparing the purified extract into nanospheres, which are then mixed with baijiu to obtain the product. Compared with traditional Polygonatum wine, the product of this invention can improve the efficient encapsulation of bioactive substances, achieve targeted delivery and slow release, significantly prolong the residence time of the drug at the site of action, promote drug penetration and absorption, and improve bioavailability.

The invention belongs to the technical field of carrier delivery, and provides a W / O / W emulsion for efficiently delivering active substances to intestinal tracts and a preparation method of the W / O / W emulsion. The W / O / W emulsion provided by the invention is prepared by constructing an outer water phase through hydrated whey protein isolate and cellulose nanocrystals, taking a glycerol-trehalose aqueous solution as an inner water phase, compounding an emulsifier oil phase and performing high-speed dispersion twice. According to the preparation method, the storage stability (TSilt, 5, Zeta potential absolute value gt, 30mV for storage in 5d) and digestion tolerance of the emulsion can be remarkably improved through the synergistic effect of the protein-cellulose nanocrystals, and internal-phase bioactive substances are prevented from being inactivated through dual protection; the external water-phase cellulose nanocrystals form a physical barrier, so that the digestion rate of whey protein is delayed (the digestion rate at the gastric digestion stage is reduced by more than 40%), the controlled release of functional components is realized, and a structural guarantee is provided for an oral delivery system.

This invention provides a method for preparing fermented pig feed based on bamboo powder and mycelium residue, belonging to the field of livestock and poultry feed preparation technology. Using bamboo powder and mycelium residue, a byproduct of edible fungi cultivation with bamboo powder as the core substrate, as raw material, the invention achieves efficient degradation of lignocellulose and bioconversion of nutrients in the bamboo powder and mycelium residue through core steps such as enzymatic pre-cell wall disruption pretreatment, segmented solid-state fermentation with compound functional microbial agents, and precise nutrient compounding. The resulting fermented pig feed is low in crude fiber, high in crude protein, palatable, and rich in bioactive substances. It can replace 10%-30% of traditional corn-soybean meal diets, significantly reducing feed costs for pig farming, improving pig growth performance and pork quality, and simultaneously constructing a closed-loop circular economy model of bamboo-fungi-livestock, possessing significant economic, ecological, and social benefits.

Disclosed herein are compositions including a plurality of nature-derived lipid particles (NLPs) comprising phospholipids, essential oils, blends of essential oils and polar lipids, and optionally surface modifiers, and further comprising bioactives, wherein the NLPs comprise a hydrophobic core, for use in a variety of agricultural methods.

The invention discloses a preparation method of goat milk small molecule peptides, which solves the technical problems of low enzymolysis efficiency, heavy goaty flavor and insufficient uniformity in goat milk peptide preparation in the prior art by constructing a compound enzyme system and adding glutaminase and other enzymes to perform enzymolysis on goat milk. The goat milk small molecule peptide product prepared by the preparation method is high in homogeneity, high in 500-1000 Da peptide fragment yield, and high in goaty smell removal rate, and also retains bioactive substances. Meanwhile, in the deep processing process of the goat milk, flavor active substances such as short-chain fatty acid are enriched in fat components. If being directly discarded, not only is resource waste caused, but also environmental burden is possibly introduced. Therefore, when the goat milk small molecule peptide is prepared, the natural mutton fat is synchronously recovered and purified, and a protein-fat synergistic high-value utilization system is formed.

In various embodiments of the present disclosure, compositions exhibiting metabolism boosting effect are described. In various examples, compositions comprise a synergistic combination of at least one plant, root, seed, or fruit material, or extract thereof, or bioactive therefrom; at least one vitamin, essential trace mineral, or enzyme or vitamin cofactor; at least one amino acid; and at least one antioxidant. In various aspects, metabolism enhancing compositions are formulated as loose powders filled into capsules as orally administered dietary supplements. In various embodiments, compositions of the present disclosure are used to treat metabolic syndrome in subjects expressing symptoms thereof.

The invention belongs to the technical field of meat product processing, and discloses a meat composite curing agent as well as a preparation method and application thereof. The meat composite pickling agent comprises the following raw materials in parts by weight: 20-30 parts of roxburgh rose pomace enzymatic hydrolysate, 5-10 parts of mushroom peptide, 3-6 parts of celery powder, 0.5-1.5 parts of compound bacterium powder, 10-15 parts of spice powder and 8-12 parts of auxiliary materials. Wherein a preparation method of the rosa roxburghii tratt fruit residue enzymatic hydrolysate comprises the following steps: adding rosa roxburghii tratt fruit residues into a tea polyphenol solution, carrying out enzymolysis treatment after ultrasonic treatment, and filtering to obtain filtrate; the celery powder is obtained by drying celery stems at low temperature and then crushing the dried celery stems. The meat composite curing agent contains various micromolecular bioactive substances, can effectively permeate into meat tissues when being used for curing meat, reduces generation of typical harmful substances such as heterocyclic amine and benzopyrene in high-temperature processing processes such as baking and deep-frying, and simultaneously endows meat products with coordinated fragrance, rich levels and fine taste.

The present disclosure generally relates to compositions comprising biologies and / or proteins. Some of the compositions described herein may be in the form of solid particles. In certain embodiments, the composition comprises a precipitant (e.g., interspersed with the biologic and / or protein). The composition may also comprise a dehydrating fluid (e.g., a relatively small amount of a dehydrating fluid). In some embodiments, suspensions of solid and / or substantially solid particles containing a protein and / or biologic and a precipitant are provided. For example, some suspensions described herein contain a plurality of solid particles containing a biologic and / or protein and a precipitant (e.g., a solid particle that is and / or comprises a composition described herein) suspended in an aqueous medium. Methods of forming such solid particles and other particles containing proteins and / or biologies are also disclosed.

The invention relates to the technical field of compound fertilizers, in particular to a preparation process of a nitrogen-phosphorus-potassium balanced fertilizer containing inositol and protein, which comprises the following steps: taking a porous material as a carrier, adding phosphorus-potassium powder and monopotassium phosphate mother liquor, stirring, mixing and drying to obtain a carrier material loaded with phosphorus and potassium, spraying a compound solution containing inositol and protein into the carrier material loaded with phosphorus and potassium, and preparing the nitrogen-phosphorus-potassium balanced fertilizer containing inositol and protein. The preparation method comprises the following steps: stirring, mixing and drying to obtain a carrier material loaded with inositol and protein, spraying a urea solution, adding potassium sulfate powder, granulating, screening to obtain particles with qualified particle size, spraying a coating solution containing humic acid and chitosan, and drying to obtain the nitrogen-phosphorus-potassium balanced fertilizer containing inositol and protein. The balanced fertilizer obtained by the preparation process has a relatively good utilization rate, not only provides balanced nitrogen, phosphorus and potassium, but also realizes triple effects of nutrition, growth stimulation and soil improvement by adding bioactive substances (inositol and protein) and natural coating materials (humic acid and chitosan).

This invention provides a coffee pericarp enzyme, its specific compound fermentation agent, and a preparation method, belonging to the field of enzyme production technology. The preparation method of the coffee pericarp enzyme of this invention includes the following steps: mixing coffee pericarp powder with sacha inophyllum pomace saccharides, and sequentially subjecting the mixture to fermentation with *Saccharomyces cerevisiae* YNXC003 and anaerobic fermentation with *Bifidobacterium bifidum* YNXC004 to obtain the coffee pericarp enzyme. This invention uses coffee pericarp powder and sacha inophyllum pomace saccharides as compound raw materials, combined with a specific fermentation agent, and employs a segmented fermentation mode. This not only fully releases the nutritional activity of the two raw materials, significantly improving the nutritional level and flavor of the enzyme, but also endows the enzyme with physiological functions such as lowering blood sugar. The total acid content of the coffee pericarp enzyme of this invention is 8-12 g / L, the total phenol content is 1.5-2.5 g / L, and it is rich in short-chain fatty acids, polyphenolic compounds, amino acids, and other bioactive substances, exhibiting significant blood sugar lowering effects.

The invention relates to the related fields of special diet for sports nutrition and preparation of bioactive substances, in particular to high-branched-chain amino acid eel peptide and application thereof in special diet products for sports. The eel processing leftovers are used as raw materials, waste is turned into wealth through the synergistic effect of the compound enzyme and the ultrafiltration membrane filtration separation technology, the resource utilization rate and the product additional value are increased, the content of branched chain amino acid is effectively increased, the purity is high, and the eel peptide is suitable for industrial production. The ginger powder is cooked to remove fishy smell and bitterness, hydrolysis is more accurately controlled through the compound enzyme, bitter peptides are prevented from being generated, the added kumquat juice powder and sweet orange juice powder can further cover slight peculiar smell possibly left by the peptides, the bitter taste of the eel peptide product is reduced, the eel peptide product has good palatability, and the taste of the eel peptide product is improved. And the product is good in solubility and fluidity and wide in application range.

The present application relates to the technical field of food processing, and provides a method for extracting bioactive substances from selenium-rich tea, which comprises the following steps: S1. crushing selenium-rich tea leaves, soaking in double-distilled water for a period of time, then placing in a microwave instrument for microwave extraction for a period of time, cooling, filtering, and obtaining a polysaccharide extract; S2. placing the polysaccharide extract in a supercritical carbon dioxide extraction kettle, setting the extraction temperature to 28.3-33.6 DEG C and the extraction pressure to 6.1-8.3 Mpa, and introducing carbon dioxide gas into the supercritical carbon dioxide extraction kettle; after extraction for a period of time, opening a separation kettle connected to the supercritical carbon dioxide extraction kettle, and connecting the separation kettle with a carbon dioxide gas cylinder, continuing to extract for a period of time, and obtaining bioactive substances, which can green, efficient and convenient to extract different bioactive substances from selenium-rich tea in turn and is suitable for industrial production.

The invention discloses a lactoferrin nanofiber and a preparation method thereof, and the preparation method comprises the following steps: adjusting the pH value of a lactoferrin aqueous solution with the mass volume concentration of 2.5% (w / v) to 2.0, then heating at 90 DEG C for 4 hours, and finally cooling to terminate the reaction to obtain the lactoferrin nanofiber. The method is simple in process, controllable in condition and high in fiber forming speed. The prepared lactoferrin nanofiber is worm-shaped, rich in beta-folded structure, has positive charges on the surface, has good colloidal stability and functional characteristics, can be used as an excellent carrier material for encapsulating and protecting hydrophobic bioactive substances, and has wide application prospects in the fields of functional foods and medicines.

The invention relates to a novel and multifunctional instant curd formulation. This innovation achieves simultaneous lactose hydrolysis and protein coagulation within seconds of reconstitution. This innovation uniquely defers the acidification reaction until the point of use, producing a stable and shelf-friendly powder that instantaneously forms bioactive curd with therapeutic potential. The curd matrix generated serves as a smart carrier capable of delivering medicines, probiotic bacteria, or enzymes, which become activated and effective in situ due to the controlled biochemical environment created by the curd's specific pH. This invention represents a significant advancement over prior art by combining rapid curd formation with simultaneous generation of bioactive substances and enhanced delivery capabilities. It has broad applicability in food technology, pharmaceutical delivery, with particular utility in patient-friendly formulations suitable for diverse populations. The process and product offer improved convenience, efficacy, and multifunctionality without compromising stability or safety.

The application relates to a high internal phase emulsion ink material and a preparation method and application thereof, and belongs to the technical field of emulsion ink material preparation. The preparation method of the high internal phase emulsion ink material provided by the application is as follows: a pulse electric field is used to treat a soybean protein isolate solution, then the soybean protein isolate solution is mixed with a polysaccharide solution as an aqueous phase, then vegetable oil and a bioactive substance are mixed as an oil phase, and finally the aqueous phase and the oil phase are mixed and high-speed sheared to prepare the high internal phase emulsion ink material. The high internal phase emulsion ink material prepared by the application has high stability after freeze-thaw storage and high retention rate of the bioactive substance, can effectively embed the bioactive substance, better realizes slow release of the bioactive component, achieves the purpose of targeted transport, improves the retention capacity of the emulsion to the internal phase substance under the freeze-thaw condition, has great application prospect and development potential in the preparation of 3D printing functional food, and can provide a new technical direction and technical support for the 3D printing functional food.

The application discloses a kind of rock carp parent fish ecological strengthening cultivation feed and preparation method thereof, belong to feed preparation method technical field, it includes the following by weight parts raw materials: fish meal 28-32 parts, bean cake 17-22 parts, vegetable cake 13-17 parts, corn 20-25 parts, blood globule powder 3-7 parts, water earthworm 8-15 parts, mineral salt premix 1-3 parts, vitamin premix 0.5 parts-1 part.In the application, by adopting low-temperature conditioning granulation and gradient cooling drying process, the potency of heat-sensitive vitamins and bioactive substances is maximized, and by post-spraying refined fish oil and vacuum nitrogen packaging, the highly unsaturated fatty acids required for the development of parent fish gonads are strengthened, oxidation and spoilage of the feed are prevented, and the shelf life is extended. The feed has good palatability, stable granules, can enhance the reproductive performance and physical condition of rock carp parent fish, and provides reliable technical support for resource protection and ecological breeding of rare and unique fish in the upper reaches of the Yangtze River.

The present application belongs to the technical field of edible mushroom cultivation, and particularly relates to an edible mushroom culture medium and an edible mushroom cultivation method. The edible mushroom culture medium comprises the following components in parts by weight: 25-30 parts of Tribulus terrestris L. hard thorn enzymatic product, 20-25 parts of magnetic wheat bran, 10-15 parts of cottonseed hulls, 12-15 parts of corn cob powder, 5-7 parts of soybean meal, 0.5-1 part of light calcium carbonate and 0.5-1 part of quicklime, and the water content is 65-70%. The present application is characterized in that the discarded Tribulus terrestris L. hard thorn residues are pulverized and then subjected to compound enzymatic hydrolysis, which not only releases a large amount of soluble sugars, but also retains the specific bioactive substances of Tribulus terrestris L., and in the case of providing sufficient lignin source, the substrate fertility is also enhanced, the metabolic activity of edible mushroom mycelium is significantly enhanced, the utilization rate of nutrients in the culture medium by edible mushrooms is improved, the waste utilization of Tribulus terrestris L. hard thorn residues is realized, resource waste is avoided, and sustainable development is achieved.