The invention relates to a brain-building intelligence-reinforcing pill for treating brain exhaustion psychosis. Polygonum multiflorum, jujube kernel, polygala tenuifolia, schisandra chinensis, radix ophiopogonis, fushen, rehmannia root and fructus ligustri lucidi in the prescription aim at the symptoms of liver and kidney deficiency, deficiency fire disturbance, cardiac-splenic lesion, worry beyond measurement, damage to brain nerves, insomnia, lightness in the head, headache, palpitation, dysphoria, irritability, soreness and weakness of waist and knees, reddened yellow thin-furred tongue and slow and thin pulse. Patients suffering from brain empty and brain failure are weak in body, are irritated, overstrain their brains, liver and kidney deficiency and hyperactivity happen accordingly. Therefore, the patients suffer from lightness in the head, headache, lower yin deficiency and upper yang deficiency, feels ill at ease, suffers from palpitation and insomnia and are agitated and irritated. Therefore, the pill is utilized to nourish heat and spleen, enabling the patients to calm down and nourish the deficiency of the brain through an external source. Angelica sinensis, radix paeoniae alba and radix bupleuri in the prescription are used for smoothing liver, promoting qi, nourishing blood and liver, adjusting qi and smoothing emotions. The pill with traditional Chinese medicines in full prescription has the functions of smoothing liver and qi, promoting blood circulation, removing stasis, nourishing blood, enriching the blood, enabling qi and blood to be vigorous and tranquilizing and allaying excitement and has the advantages of nourishing and flourishing the brain. Various mental diseases cannot reappear after the patients are cured.