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520 results about "Rash" patented technology

Noticeable change in the skin in terms of texture and color.

Modified release compositions of milnacipran

A once-a-day oral milnacipran modified release formulation has been developed. The formulation comprises an extended release dosage unit (optionally containing the immediate release portion) coated with delayed release coating. The milnacipran composition, when administered orally, first passes through the stomach releasing from zero to less than 10% of the total milnacipran dose and then enters the intestines where drug is released slowly over an extended period of time. The release profile is characterized by a 0.05-4 hours lag time period during which less than 10% of the total milnacipran dose is released followed by a slow or extended release of the remaining drug over a defined period of time. The composition provides in vivo drug plasma levels characterized by Tmax at 4-10 hours and an approximately linear drop-off thereafter and Cmax below 3000 ng / ml, preferably below 2000 ng / ml, and most preferably below 1000 ng / ml. The composition allows milnacipran to be delivered over approximately 24 hours, when administered to a patient in need, resulting in diminished incidence or decreased intensity of common milnacipran side effects such as sleep disturbance, nausea, vomiting, headache, tremulousness, anxiety, panic attacks, palpitations, urinary retention, orthostatic hypotension, diaphoresis, chest pain, rash, weight gain, back pain, constipation, vertigo, increased sweating, agitation, hot flushes, tremors, fatigue, somnolence, dyspepsia, dysoria, nervousness, dry mouth, abdominal pain, irritability, and insomnia.
Owner:COLLEGIUM PHARMA INC

Modified release compositions of milnacipran

InactiveUS20060024366A1Reduce incidenceDiminished decreased intensityCoatingsDrageesPalpitationsRash
A once-a-day oral milnacipran modified release formulation has been developed. The formulation comprises an extended release dosage unit (optionally containing the immediate release portion) coated with delayed release coating. The milnacipran composition, when administered orally, first passes through the stomach releasing from zero to less than 10% of the total milnacipran dose and then enters the intestines where drug is released slowly over an extended period of time. The release profile is characterized by a 0.05-4 hours lag time period during which less than 10% of the total milnacipran dose is released followed by a slow or extended release of the remaining drug over a defined period of time. The composition provides in vivo drug plasma levels characterized by Tmax at 4-10 hours and an approximately linear drop-off thereafter and Cmax below 3000 ng/ml, preferably below 2000 ng/ml, and most preferably below 1000 ng/ml. The composition provides a therapeutic effect over approximately 24 hours, when administered to a patient in need, resulting in diminished incidence or decreased intensity of common milnacipran side effects such as sleep disturbance, nausea, vomiting, headache, tremulousness, anxiety, panic attacks, palpitations, urinary retention, orthostatic hypotension, diaphoresis, chest pain, rash, weight gain, back pain, constipation, vertigo, increased sweating, agitation, hot flushes, tremors, fatigue, somnolence, dyspepsia, dysoria, nervousness, dry mouth, abdominal pain, irritability, and insomnia.
Owner:COLLEGIUM PHARMA INC

Process for the removal of arsenic and chromium from water

The present invention provides low cost and highly effective method for the removal of arsenic and Cr(III&VI) from contaminated water using zinc peroxide nanoparticles (20±5 nm) capped with glycerol/PVP/TEA upto the permissible range of drinking water. As Arsenic and chromium occurs naturally in the earth's crust. When rocks, minerals, and soil erode, they release arsenic and chromium into groundwater. Arsenic and chromium occurs naturally in varying amounts in groundwater in various parts of country from ppb level to ppm level. The average concentration of arsenic and chromium as per USEPA standard in drinking water it is 10 parts per billion and 0.05 ppm (50 ppb) respectively. In drinking water the level of chromium is usually low as well, but contaminated water may contain the dangerous Cr(III&VI). Although Cr(III) is an essential nutrient for humans and shortages may cause heart problems, disruptions of metabolisms and diabetes. But the uptake of too much Cr(III) can cause health effects as well, for instance skin rashes. Cr(VI) is known to cause various health effects Skin rashes, upset stomachs, respiratory problems, weakened immune systems, kidney and liver damage and lung cancer The persons who are drinking water having upto 50 ppb of arsenic and 0.05 ppm chromium over for many years could experience skin damage or problems with their circulatory system, and may have an increased risk of getting cancer. Keeping the above facts we developed a cost effective nanoparticles for the removal of Arsenic and Cr(III&VI) from potable water upto potable range.
Owner:COUNCIL OF SCI & IND RES

Pure traditional Chinese medicine mask with effects of spot removing, acne removing, wrinkle removing and whitening

The present invention relates to a pure traditional Chinese medicine mask with effects of spot removing, acne removing and whitening, wherein the mask comprises mung bean, ma-yuen jobstears seed, seaweed, lemon, aloe, cordyceps sinensis, pangolin piece, pearl, dangshen, peppermint, safflower, peach seed, almond, angelica archang lica, largehead atractylodes rhizome, common bletilla tuber, baikal skullcap root, dan-shen root, silkworm larva, common motherwort herb, fragrant solomonseal rhizome, smilax china, ginkgo leaf, fortune firethorn fruit and root, and other main raw materials, and is a full-nature nutritional substance with no toxic-side effect. With the mask, a conditioning effect is provided based on skin detoxification cycle, skin metabolism cycle is promoted, pores are cleaned and minimized, problems of dull complexion, large pores, dark yellow complexion, oiliness, acne, comedo, yellow qi and the like of the whole skin can be conditioned and cleaned, significant treatment effects are provided for acne, rash, comedo and the like, and functions of nutrition, skin health care and whitening are provided. In addition, the traditional Chinese medicine mask is used in more than 200 beautifying institutions in the region, and is compensatedly used in more than 600 national beautifying institutions according to contract agreements, wherein more than 80 beautifying chain institutions are included.
Owner:张淯河

Method of controlling rash advance at tail end of route and vehicle equipment of controlling rash advance at tail end of route

The invention discloses vehicle equipment for controlling the rash advance at the tail end of a route. The vehicle equipment comprises a positioning module, a calibration module, a speed acquisition module, a calculation module, a judging module, and a braking output module; the positioning module is used for obtaining the satellite positioning of a vehicle, the calibration module is used for positioning and calibrating the satellite positioning and the actual location of the vehicle when the vehicle speed is at zero; the speed acquisition module is used for real-time acquisition of the current speed of the vehicle and using the current speed as the calculation speed; the calculation module is used for calculating the distance of the vehicle currently apart from the end and the distance of braking corresponding to the current velocity; the judging module is used for determining whether the difference between the distance of the vehicle currently apart from the end and the distance of braking is less than the preset safety margin; the braking output module is used for issuing a braking instruction to a braking system when the difference between the distance of the vehicle currently apart from the end and the distance of braking is smaller than the preset safety margin. The invention also discloses a method for controlling the rash advance at the tail end of the route. By the adoption of the vehicle equipment for controlling the rash advance at the tail end of the route, the positioning precision is high, the structure is simple, the maintenance cost is low, and the requirements of a test route can be met.
Owner:ZHUZHOU ELECTRIC LOCOMOTIVE CO LTD
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