451 results about "Ivermectin" patented technology

The invention belongs to the field of plant protection, and relates to an agricultural composition containing antibiotics and plant source materials, wherein antibiotic is one or several selected from abamectin, ivermectin, milbemectin, pleocidin, nikkomycin, liuyangmycin, streptomycin, polyoxins, chunleimeisu, jinggangmeisu, ningnanmycin and the like; the plant source material is one or several of smashing material, crude extract, or active ingredient of derris, thunder god vine, tobacco, pyrethrum, tagetes, crofton weed, radix stemonae, cayenne, macleaya cordata, radix sophorae flavescentis and the like. The composition provided by the invention expresses well synergism in a certain matching range, and has excellent control efficiency for crop diseases and pests.

The invention includes compositions for transmucosal administration to an animal comprising at least one active agent and a pharmaceutically acceptable carrier. A preferred active agent is selected from the group consisting of meloxicam, carprofen, enrofloxacin, clemastine, diphenhydramine, digoxin, levothyroxine, cyclosporine, ondansetron, lysine, zolpidem, propofol, nitenpyram, ivermectin, milbemycin, and pharmaceutically acceptable salts, solvates and esters thereof. In another embodiment, the invention includes methods of treating or preventing a condition in an animal comprising transmucosally administering a composition comprising a therapeutically or prophylactically effective amount of an active agent and a pharmaceutically acceptable carrier.

Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.

Microencapsulated formulations of macrolide lactones (abamectin, milbemectin, milbemycins emamectin, avermectins, ivermectins) wherein the active ingredient is protected from UV-degradation, with exceptional release characteristics resembling those of an emulsion concentrate or, if desired, of long-lasting effect; further with appropriate rheological properties, and with reduced toxicity. The invention provides a unique microencapsulation process for the chemical stability and biological activity of mectins, e.g. abamectin, and provides microcapsules of mectins to be used in formulations CS, WG/CS, ZC, EC/CS and any formulation type containing microcapsules and combination with other biologically active ingredients.

The invention provides a pymetrozine-containing ultralow volume liquid agent, and belongs to the field of pesticides. The ultralow volume liquid agent consists of pymetrozine or active ingredient compounded by using the pymetrozine and an active ingredient II, and the balance of aids and solvent; and the active ingredient II is any one of bifenthrin, beta-cypermethrin, lambda-cyhalothrin, cyfluthrin, fenpropathrin, deltamethrin, etofenprox, triazamate, tolfenpyrad, chlorantraniliprole, flubendiamide, ethiprole, abamectin, emamectin benzoate, ivermectin, sec-butyl phenyl-N-methyl carbamate, buprofezin, hexaflumuron, flufenoxuron, chlorbenzuron, diafenthiuron, indoxacarb, 1,2-Dibenzoyl-1-tert-butylhydrazine and tebufenozide. The ultralow volume liquid agent is used for preventing and controlling multiple pests on paddy, wheat, corn, vegetables, tobacco, tea trees, fruit trees and sugarcane by ultralow volume spraying, low volume spraying or ultralow volume electrostatic spraying. The ultralow volume liquid agent has the advantages of low water consumption, high effect, long acting time, synergy and the like.

The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus tetrahydropyrimidines. An examples of a tetrahydropyrimidine includes pyrantel. A pharmaceutical formulation is provided for use in the treatment of helminthiasis of mammals, and particularly tapeworm, hookworm, roundworm and heartworm of domestic animals and farm animals. The present invention also provides a method of treating helminthiasis in mammals, which method comprises administering to the mammal in need thereof an anthelmintically effective amount of a pharmaceutical formulation of the invention.

The invention discloses an insecticide acaricide taking an oligose and macrolides composition as a synergist, and in particular relates to a synergism composition capable of enhancing the insecticiding effect of the insecticide acaricide. The composition comprises oligose and a macrolides insecticide; the macrolides insecticide is abamectin, pleocidin, emamectin benzoate or ivermectin; the oligose is pectic oligosaccharide, sodium alginate oligosaccharides or chitosan oligosaccharide; the mass part ratio of the oligose to the macrolides insecticide is (1-30):(1-10). The synergism composition can enhance the insecticidal efficacy of the insecticide acaricide and realize the synergism effect with other insecticide acaricides.

Disclosed is an oil soluble pesticide nm capsule and preparation method, having weight ration of: pesticide: 0.5-4%; high molecular compound: 8-25%; mixed-surfactant: 8-20%; cosurfactant 3-10%; crosslinking agent 0.5-1.0%; organic solvent 3-10%; water: added to 100%, wherein the high molecular compound is selected from sodium lignosulfonates, chitosan, gum arabic or glutin, one or two is/are selected for agglutination reaction, forming capsule skin of the nm capsule; the capsule core is pesticide bulk drug, selected from diflubenzuron, emamectin benzoate, abamectin, imidacloprid, ivermectin or highly active cypermethrin. The mixed-surfactant adopts nonionic surfactant and anionic surfactant for compound. The pesticide nm controlled release preparation prepared by the invention is easy in storage, high in stability, large in drug-loading rate and high in dispersion.

The invention discloses ultralow volume liquid containing spirotetramat, which is prepared by using spirotetramat or a compound of the spirotetramat and an activated ingredient II as an activated ingredient and adding adjuvant and solvent. An activated ingredient B is optional one of etofenprox, efficient cypermethrin, deltamethrin, tolfenpyrad, chlorantraniliprole, flubendiamide, ivermectin, indoxacarb, RH-5849 (1, 2-dibenzoyl-1-tert-butylhydrazine) and tebufenozide. The ultralow volume liquid containing spirotetramat has the advantages of convenience in processing, long-term effect, a target being not easy to resist the pesticide, low environmental pollution, pesticide and water economization, increase of pesticide utilization rate, and can be used for controlling various pests on rice, wheat, vegetables, tobacco plants, tea plants, fruit trees and sugarcanes by means of ultralow volume spray, low volume spray or ultralow volume static spray.

The invention relates to a medicine for killing solenopsis invicta buren and the use method thereof. The medicine comprises 0.0025%-5.0000% of insecticidal active constituent according to mass percent, which is selected from one of or the mixture of the following component: fipronil, fluorine insects amines, spinosad, Arab-Israeli (Iraq) ivermectin, vants hydrazone, imidacloprid, rotenone, matrine, Yanggakdo twisting glycosides, cicuta alkali, boric acid; 15%-25% of glucide, 10%-25% of thickening agent, 0.005%-6% of menstruum, 0.01%-0.03% of preservative and the rest of water. The use method of the solenopsis invicta buren baits is that: pouring suitable quantity baits agent into a container with nozzle, and diluting the baits agent with water, then agitating the anthill lightly, and sprinkling the water-based baits agent on the body surface of the ergates and the soil above the anthill surface after a mass of ergates come out of the anthill. The manufacturing process of the medicine is simple, the cost is lower, and the use method is suitable for large-scale spraying.

A topical gel composition comprising between about 0.005 and 1.0% ivermectin, between about 30 and 40% of a pharmaceutically acceptable alcohol, between about 30 and 40% of a pharmaceutically acceptable glycol, and a pharmaceutically acceptable carrier, useful for treating Pediculosis capitis infestation in a human patient.

The invention relates to a stabilized premix feed or feed-like formulation that has an extended shelf life due to a decrease of the degradates of the active ingredient by controlling the amount of an already existing stabilizer in the formulation. The feed premix is used in the treatment or prophylaxis of parasites in mammals, in particular swine and horses. The invention further relates to a method to extend the shelf life of a stable premix feed or feed-like formulation for the treatment or prophylaxis of parasite infestation in swine and horses comprising controlling the amount of an already existing antioxidant or stabilizer in the formulation to decrease or to prevent the formation of acid/base catalyzed decomposition of the active ingredient.

The invention belongs to the field of pesticide and fertilizer compounding, and relates to a pesticide fertilizer special for root-knot nematode prevention. The pesticide fertilizer is prepared as follows: according to the infestation habits of root-knot nematodes and the fertilizer requirement law of crops, selecting the pesticide active ingredients ivermectin and/or fosthiazate, selecting one or more kinds of materials capable of improving the resilience of crops, such as chitin, humic acid and seaweed fertilizer, selecting and adding major element fertilizer, secondary element fertilizer and minor element fertilizer, and adding a carrier, so as to obtain the pesticide fertilizer special for root-knot nematode prevention. The ingredients in the pesticide fertilizer match with the infestation habits of root-knot nematodes and the nutrient absorption law of crops, so as to improve the pesticide and fertilizer utilization rate, reduce the investment costs, improve the soil environment, and lessen the agricultural non-point source pollution.

Physically and chemically stable, oxidation-resistant, cosmetic/dermatological inverse emulsions contain a therapeutically effective amount of at least one avermectin compound, notably ivermectin, a glycolic or aqueous/glycolic dispersed hydrophilic phase, a continuous lipophilic phase and an emulsifier having an HLB ranging from 2 and 7, and are useful for the treatment of a variety of dermatological conditions/afflictions, e.g., rosacea.

Administration of at least one compound of the family of the avermectins or of the family of the milbemycins, notably ivermectin, is useful for the treatment of ophthalmic pathologies, including ocular rosacea.

The invention relates to an albendazole suspension containing ivermectin nanoemulsion, which is characterized by comprising the following components in parts by weight: 1-30 parts of albendazole, 0.01-1 part of ivermectin, 1-10 parts of oil phase, 1-20 parts of cosurfactant, 1-25 parts of dispersant (emulsifier), 0.01-10 parts of suspending agent, 0.01-10 parts of thickening agent and 0.1-10 parts of preservative. The invention ingeniously uses the oil phase of the ivermectin nanoemulsion as a wetting agent for wetting albendazole, thereby reducing the consumption of the surfactant and solvent, enhancing the safety of the preparation and greatly lowering the cost of the preparation.

The invention relates to ivermectin sustained-release microspheres used as an animal medicine for animal injection, and a preparation method thereof. The invention belongs to an interdisciplinary field of biomedical polymer materials and controlled release preparations. The invention discloses ivermectin sustained-release microspheres, which are characterized in that: the ivermectin sustained-release microspheres have particle sizes of 0.1 to 10mum, a medicine loading capacity of 20% to 35%, and an entrapment rate of above 80%. The preparation method of the ivermectin sustained-release microspheres comprises steps that: a carrier material and the medicine ivermectin with a mass ratio of 1:1-10 are dissolved in an organic solvent; the solution is processed through supersonic wave or mechanical stirring, such that the solution is emulsified into an oil phase, wherein a volume ratio of oil phase to water phase is 1:5-10; under a temperature of -10 DEG C to 30 DEG C, the oil phase is injected into a water phase disperse medium solution step-by-step; constant-temperature magnetic stirring is carried out with a rotation speed of 400 to 10000rpm, the mixture is sufficiently emulsified, such that an S/O/W type emulsion is obtained; the emulsion is stirred under room temperature for 3 to 4 hours, such that the organic solvent is sufficiently volatilized; the obtained product is centrifuged, washed, collected, and is vacuum-dried with a pressure of 0.01 to 0.04MPa under room temperature for 10 to 12 hours or is lyophilized under a temperature of -0 DEG C to -20 DEG C. With the processes, ivermectin sustained-release microspheres with particle sizes of 0.1 to 10mum are obtained.

The invention relates to an agricultural composition containing chitosan oligosaccharide and fipronil, the agricultural composition is characterized by also containing one or a plurality of component from an insecticidal component, a sterilization component, a plant growth regulator and a fertilizer component, the insecticidal component is selected from one or a plurality of component of abamectin, chlorpyrifos, fosthiazate, thiamethoxam, phoxim, spinosad, isazofos, ivermectin, profenofos, thiodicarb and imidacloprid, the sterilization component is selected from one or a plurality of component of ethylicin, azoxystrobin, fludioxonil, hymexazol, difenoconazole and propiconazole, the plant growth regulator is selected from one or a plurality of component of mepiquat chloride, naphthylacetic acid, chlormequat chloride, uniconazole, paclobutrazol and indolebutyric acid, and the fertilizer component is selected from one or a plurality of component of nitrogen, phosphorus, potassium, calcium, magnesium, boron, zinc and amino acids. The agricultural composition can be one of a granule agent, a microcapsule agent, an absorbent product, a water agent, a water emulsion agent, a suspending agent, a water dispersible granule agent, a wettable powder agent and a microemulsion agent, and is used for root irrigation, sprinkling and pouring, furrow application pesticide-clay mixture or hole application, and the agricultural composition is used for the control of plant diseases and insect pests and regulation of plant growth.

The invention discloses an acaricidal composition which comprises a synergic effective dose of acaricidal material bifenazate A and at least one macrolide acaricidal compound B as active components, wherein the macrolide acaricidal compound B is selected from avermectin, pleocidin, emamectin benzoate and invermectin, and based on the active components, the proportion of A to B according to parts by weight is 5-70:0.1-10. The composition can be prepared into oil emulsion, suspending agents, aqueous emulsion, micellar emulsion, wettable powder, microcapsule agents and other formulations for controlling acarid of various crops such as fruit trees, tea trees, vegetables and the like.

The invention discloses a method for measuring residues of seven pesticides in wool fat by liquid chromatography-tandem mass spectrometry, and belongs to a chemical detection method. A liquid-liquid extraction frozen degreasing method is used as pretreatment; and the pesticide residues in the wool fat are detected and analyzed by the liquid chromatography-tandem mass spectrometry. According to the detection method disclosed by the invention, a wool fat sample extract solution is not required to be concentrated and can be measured in a machine only after being purified, so that the detection is quick and accurate, and the sensitivity is higher; the using amount of solvents is small, the extraction efficiency is high, grease can be completely removed, and the target retaining capacity is high; the residues of seven pesticides, such as cyromazine, dicyclanil, diflubenzuron, triflumuron, rotenone, abamectin and ivermectin can be detected at the same time; the target response signal is strong; the average recycling rates are 66.77-105.48 percent respectively; the relative standard deflection RSD is 1.38-8.09 percent; and the method has certain actual application and innovative signification.