80 results about "Ciprofloxacin" patented technology

The invention discloses a method for degrading antibiotics in wastewater based on chitosan aerogel. The method comprises the following steps: adding chitosan aerogel Co-PBA / CS and potassium hydrogen peroxymonosulfate into the antibiotic-containing wastewater, and degrading under stirring. The method provided by the invention has a ciprofloxacin degradation capability of 94.7%. In addition, the material also has excellent self-cleaning and photo-thermal conversion performance, and can realize surface cleaning. The multifunctional aerogel provides a new strategy for removing pollutants such as ciprofloxacin in a complex and severe water environment.

The invention relates to a preparation method and application of an alkali-activated iron tailing geopolymer adsorbent. According to the method, an iron tailing geopolymer is prepared through an alkali activation method, that is, an aluminosilicate structure in iron tailings is destroyed in an alkali activation mode, so that silica tetrahedron and alumina tetrahedron structures of the iron tailings are reconstructed, and a geopolymer material with adsorption capacity is prepared; on the basis, a foaming agent hydrogen peroxide solution is introduced to adjust the performance, and parameters such as modulus, water cement ratio and curing temperature of the alkali activator are respectively adjusted to prepare an optimal sample. The iron tailing geopolymer adsorbent material which is high in adsorption rate and good in stability is obtained, and the effect of adsorbing residual ciprofloxacin in wastewater is remarkable.

The invention discloses a modified chitosan-based antibacterial material as well as a preparation method and application thereof, and belongs to the technical field of antibacterial materials. The ciprofloxacin grafted quaternized chitosan is successfully synthesized by taking the chitosan as a raw material, and the water solubility and the antibacterial ability of the chitosan are effectively improved. The antibacterial diameters of the ciprofloxacin grafted quaternized chitosan prepared by the preparation method disclosed by the invention on escherichia coli and staphylococcus aureus are respectively 35.34 to 39.06 mm and 40.45 to 44.51 mm, and the minimum MIC (Minimum Inhibitory Concentration) and MBC (Minimum Mass Chitosan) can reach 0.0005 mg / mL. In addition, the antibacterial material has an obvious inhibition effect on colletotrichum gloeosporioides and aspergillus niger, and the highest antifungal rates respectively reach 53.81 + / -2.17% and 54.88 + / -1.3%. Compared with the raw materials, the antibacterial ability is greatly improved, and the grafted and modified composite material is environment-friendly and can be used for antibacterial food packaging materials.

This invention discloses a method for preparing size-tunable porous Mn / Fe-based Prussian blue nanomaterials and their applications. This invention utilizes ion doping to prepare a series of uniformly tunable Prussian blue nanoporous materials by adjusting the ratio of Mn / Fe ions. The Prussian blue nanoporous materials prepared by this invention can activate H₂O₂ and rapidly degrade a 20 ppm ciprofloxacin solution within 20 min, exhibiting good cycling performance. This invention provides a simple one-step method for preparing size-tunable porous Mn / Fe-based Prussian blue nanomaterials, characterized by high economic efficiency and a simple preparation process, resulting in significant economic and environmental benefits.

The application relates to the technical field of adsorbents, in particular to modified sodium alginate as well as a preparation method and application thereof; the preparation raw materials of the modified sodium alginate include sodium alginate, an activating agent, a mercapto reagent, a carboxylic acid compound containing an unsaturated double bond and an initiator. The application adopts natural polysaccharide sodium alginate as raw materials, which is widely sourced, non-toxic and biodegradable; a functional group carboxyl is introduced into the sodium alginate through a mercapto-alkene click reaction; the surface adsorption active sites of the modified sodium alginate are increased; the modified sodium alginate can effectively adsorb and remove methylene blue and ciprofloxacin in water; and the modified sodium alginate can still maintain good adsorption performance after being subjected to multiple cycles of adsorption-desorption.

The application discloses application of antibacterial peptide BMAP-28 and antibiotics in combined preparation of antibacterial drugs and belongs to the technical field of biological medicine. The antibiotics are selected from one or more of the following: ciprofloxacin, gentamicin and cefixime. The application combines the antibacterial peptide BMAP-28 with antibiotics such as ciprofloxacin and gentamicin, finds that the combination has a significant synergistic antibacterial effect on Enterobacter sakazii, can greatly save the dosage of the drug, reduce the toxic side effect and block the evolution process of drug resistance. Through the destruction of the bacterial cell membrane and the assistance of the antibiotic effect, the combination can effectively overcome the multiple drug resistance, widen the antibacterial spectrum and has a wide clinical application prospect.

Neisseria gonorrhoeae is one of the most common bacterial sexually transmitted infections (STI). Diagnosis depends on standard nucleic acid amplification testing (NAAT), which is impracticable in most low-resource settings, where the prevalence of this STI is highest. Consequently, such areas utilize syndromic management, which misses a high proportion of cases and leads to antibiotic overuse, contributing to the troubling rise of resistance to the commonly prescribed ciprofloxacin, cefixime and ceftriaxone antibiotics for the treatment of N. gonorrhoeae infections. A specific, highly sensitive and cost-effective lateral flow assay is disclosed that utilizes CRISPR-Cas orthologs, multiplex SHERLOCK technology and isothermal amplification via recombinase polymerase amplification (RPA) for the rapid detection of antibiotic resistance to ciprofloxacin, cefixime and / or ceftriaxone at the point of care. This approach has the potential to increase treatment efficacy in the field and mitigate the spread of antibiotic resistance.

The application discloses a complex preparation containing bovine lactoferrin and lyticase and application thereof, and belongs to the technical field of biology. The preparation is composed of bovine lactoferrin and streptococcal lyticase, and both are prepared through a baculovirus-insect cell eukaryotic expression system. Researches show that the complex preparation has a significant synergistic antibacterial effect. The complex preparation not only can effectively inhibit a plurality of gram-positive bacteria, but also can overcome the limitation that single streptococcal lyticase has weak activity on gram-negative bacteria, and significantly enhances the inhibiting effect on escherichia coli and salmonella. Especially, the complex preparation still has clear in-vitro antibacterial activity on multi-drug resistant escherichia coli such as ciprofloxacin and doxycycline, thereby providing a new way for developing a new type of drug for resisting drug-resistant bacteria.

The invention belongs to the technical field of environmental functional material preparation and water pollution treatment, and particularly relates to a cyclodextrin-based metal organic framework porous aerogel material and a preparation method thereof. The method comprises the following steps: 1) modifying cyclodextrin by using a silane coupling agent to obtain silanized cyclodextrin marked as A-CD; 2) preparing a physical composite material marked as A-CD-MOF / PNC by using A-CD, a metal salt and a chlorine-containing organic cross-linking agent as raw materials through a co-crystallization method; and 3) under the action of a catalyst, carrying out chemical reaction on the A-CD-MOF / PNC and a chlorine-containing organic cross-linking agent to prepare a chemical composite material, namely the cyclodextrin-based metal organic framework porous aerogel material. The material has the inclusion effect of cyclodextrin molecules, the amino active sites of the amino silane coupling agent and the stable heterocyclic structure of PNC, and synergistic removal of ciprofloxacin and drug-resistant bacteria is achieved.

The invention belongs to the technical field of environmental protection, and provides a preparation method and application of phosphorus-doped two-dimensional transition metal carbide porous flexible aerogel. The method comprises the following steps: chemically etching a two-dimensional transition metal carbide precursor through a lithium fluoride-hydrochloric acid system, and carrying out ultrasonic stripping and centrifugal purification to obtain a single-layer nano material suspension; then, triphenylphosphine is adopted for phosphorus doping modification, and the electronic structure is optimized through high-temperature annealing treatment; the preparation method comprises the following steps: impregnating modified melamine sponge with polyvinyl alcohol (PVA) to construct a three-dimensional porous carrier, uniformly loading a phosphorus-doped two-dimensional carbide nano-material on the surface of the carrier, and finally preparing the flexible aerogel material with a hierarchical porous structure through a freeze-drying process. According to the scheme, by doping the phosphorus element, the conductivity of the two-dimensional transition metal carbide is effectively improved, multi-layer accumulation caused by interlayer Van der Waals interaction is reduced, and excellent catalytic activity is shown for removal of antibiotics in industrial wastewater; and compared with traditional persulfate (such as potassium hydrogen persulfate), ciprofloxacin (CIP) in industrial wastewater can be efficiently degraded, and a good treatment effect is achieved.

The application belongs to the technical field of biological medicine, and provides a ciprofloxacin derivative, a preparation method and application thereof. The ciprofloxacin derivative provided by the application has a structure shown in formula I, a positively charged electrostatic effect sequence (an amino acid part) is connected to a lipid part, then is conjugated with ciprofloxacin through a linker, and a series of amphipathic ciprofloxacin derivatives are formed. The positively charged electrostatic effect sequence can enhance the interaction with a negatively charged bacterial cell membrane through electrostatic action, then the lipid part can be inserted into a phospholipid bilayer of the bacterial cell membrane, leading to the integrity of the bacterial cell membrane being destroyed, the ciprofloxacin derivative entering the cell, and finally leading to the leakage of the bacterial cell content, the breakage of the bacterial chromosome and the death of the bacterial cell. The amphipathic ciprofloxacin derivative of the application simulates the amphipathic structure and membrane destruction mechanism of an antibacterial peptide, so that the ciprofloxacin derivative exhibits a unique advantage of not being prone to drug resistance.

The invention relates to the technical field of composite photocatalysts, in particular to a sulfur-rich carbon nitride homojunction photocatalyst as well as a preparation method and application thereof. According to the specific technical scheme, common carbon nitride and sulfur-rich carbon nitride are prepared through calcination, and common carbon nitride and sulfur-rich carbon nitride are mixed and then subjected to secondary calcination, so that efficient separation of photo-induced electrons and holes in the catalyst is achieved, the utilization rate of visible light can be increased, the photocatalytic efficiency of the catalyst is obviously improved, and the photocatalytic performance of the catalyst is improved. The preparation method has the advantages of simplicity, good repeatability, environmental friendliness and the like. The catalyst has a wide prospect in the technical field of sewage treatment, and is especially suitable for removing residual ciprofloxacin antibiotics in a water body through photocatalysis.

The present application relates to a kind of porous biochar adsorbent based on polyphosphonic acid compound and alkali synergistic modification and its preparation method and application.The method includes: biomass powder is mixed with polyphosphonic acid compound solution and impregnated and dried, then is pyrolyzed first, obtains polyphosphonic acid modified biochar;Polyphosphonic acid modified biochar is mixed with alkali solution and impregnated and dried, then is pyrolyzed second, finally is pickled, washed with water and dried, and porous biochar adsorbent based on polyphosphonic acid compound and alkali synergistic modification is prepared.The porous biochar adsorbent obtained in the present application has ultra-high specific surface area and abundant micro-mesoporous hierarchical structure, surface is rich in phosphorus functional group (C-O-P and O-P), and for water body, ring ciprofloxacin, paracetamol and tetracycline and other drug and personal care product pollutants show excellent adsorption capacity and removal efficiency, suitable for pharmaceutical wastewater, medical sewage and trace new pollutants in surface water deep purification, with significant application prospect.

The application provides a macrolide derivative and a preparation method and application thereof, relates to the technical field of medicinal chemistry, and the macrolide derivative is a compound with a general structure shown in the following formula I: in the formula, A is selected from any one of alkynyl, alkenyl or piperazine; R is selected from any one of H or F; X is selected from any one of CH or N, Y is selected from any one of methyl, ethyl or cyclopropyl, and n is an integer in the range of 2-6. The macrolide derivative is connected by different lengths of ether hydrocarbons at the 3-position, thereby avoiding the problem that the instability of a synthesized compound is caused by using an ester group as a side chain to connect a quinolone group. The application successfully prepares a macrolide derivative with double targets, and the antibacterial activity of the macrolide derivative is obviously better than the antibacterial activity of erythromycin, telithromycin, clarithromycin and ciprofloxacin which only have single targets.

The invention provides Kineococcus G2 and application of the Kineococcus G2 in preparation of a pigment with antioxidant activity, the Kineococcus new strain G2 is CCTCC No. M20242602, the strain is spherical, the size is 1.0 * 1.5 mu m, the optimal growth temperature is 30-37 DEG C, the pH value is 7.0-9.0, and the salt concentration is 1.0%-2.0%. The strain G2 is not sensitive to bacitracin, ciprofloxacin and norfloxacin, and is sensitive to novobiocin, polymyxin, gentamicin, piperacillin, ofloxacin, erythromycin, streptomycin, kanamycin, rifampicin, ampicillin, vancomycin, carbenicillin, chloramphenicol, tetracycline, penicillin, cefoperazone, oxacillin, amoxicillin and neomycin. Pigment generated by fermentation of the G2 strain has good antioxidant activity, and when the concentration is 10 micrograms / mL, the scavenging activity on DPPH is 25.00%, the scavenging activity on hydroxyl radicals is 80.58%, and the iron ion reducing capacity is 1.57, which are all higher than those of contrast beta-carotenoid. The application of the new Kineococcus strain G2 can lay a foundation for the research of antioxidant drugs such as medical treatment and health care product development.

The application discloses an iron-manganese complex graphene carbon catalyst supported on a zeolite, and a preparation and application thereof, and belongs to the technical field of water treatment. The catalyst is a GC@Mn-Fe3O4 / Zeolite catalyst, which is made of nitrogen-doped graphene carbon, Fe3O4, Mn3O4 and a zeolite, and a preparation method thereof is provided. The GC@Mn-Fe3O4 / Zeolite catalyst prepared in the application can drive the metabolism of microorganisms in water to antibiotics, and effectively removes three mixed antibiotics, i.e., ciprofloxacin, sulfamethoxazole and tetracycline, in water under the condition that no external energy is input, and the removal rate can reach more than 95%. In addition, the iron-manganese complex graphene carbon catalyst is supported on the zeolite, so that the stability of the catalyst is improved, and the catalyst has a good application prospect.

This invention discloses a highly efficient method for activating peroxymonosulfate (PMS) to degrade ciprofloxacin. The method employs a cobalt- and iron-containing degradation catalytic material to activate PMS and degrade ciprofloxacin. The key feature is the preparation of a multi-cavitary bimetallic carbon framework degradation catalytic material using a metal-organic framework derivatization method. This material is supported by a carbon skeleton and chemically bonded with cobalt and iron. The prepared bimetallic carbon framework degradation catalytic material and PMS are then added to the water containing ciprofloxacin to be degraded. The bimetallic carbon framework degradation catalytic material activates the PMS, thereby degrading ciprofloxacin. This invention reduces metal leaching, improves degradation stability, and increases the efficiency of PMS activation in degrading ciprofloxacin during the degradation process. It offers advantages such as simple material preparation, low cost, convenient implementation, good catalytic degradation effect, convenient recovery, and no secondary pollution.

The invention provides a staphylococcus aureus drug resistance prediction method based on whole genome association analysis and machine learning, and belongs to the technical field of bioinformatics and artificial intelligence crossing. Five common antibiotics such as erythromycin, ciprofloxacin, penicillin, fusidic acid and methicillin are selected as modeling objects. Performing comparison and SNP site detection on a strain genome by using a reference genome, and constructing a variation matrix; then, a pyseer tool is adopted for GWAS analysis, and genetic loci significantly related to the drug resistance of each antibiotic are screened as modeling features; and for each antibiotic, respectively constructing an independent machine learning model, inputting the SNP features screened by the GWAS, and outputting a drug resistance / sensitivity classification label. Through cross validation and independent test set evaluation, the model has excellent accuracy and F1 score on multiple antibiotics. According to the method, drug resistance prediction can be achieved based on genome data without traditional drug sensitivity experiments, and the method has the remarkable time advantage, popularization value and scientific research significance.

The invention provides a preparation method and application of a molecularly imprinted surface plasmon resonance (SPR) sensing chip of ciprofloxacin (CFX). According to the chip, molecularly imprinted polymers (MIPs) are combined with an SPR technology, so that the detection sensitivity and accuracy are effectively improved, the chip has obvious signal response to CFX with lower concentration, and the detection limit can be as low as nanomole level. When the CFX molecularly imprinted SPR chip prepared by the invention is used for CFX detection, the operation steps are simple, the analysis time is short, the specificity and reproducibility are good, the operation is simple and rapid, and the chip has important practical application value.

The application belongs to the field of wastewater treatment, and discloses a three-dimensional porous water treatment material synthesis method and application of purifying wastewater. The three-dimensional porous water treatment material is prepared by a hydrothermal synthesis method, and is hydrophobicity-regulated to form a multifunctional three-dimensional porous water treatment material. The surface of the three-dimensional porous water treatment material is rich in pore structures, and has the advantages of large adsorption capacity, improved adsorption performance on ciprofloxacin, and oil-water separation application. The three-dimensional porous water treatment material can remove antibiotics in wastewater and realize oil-water separation, and has the advantages of simple preparation process, excellent treatment effect, excellent adsorption performance, and wide application prospect.

The invention discloses a preparation method and application of an aromatic dicarboxylic acid-terbium complex fluorescent sensor array. The fluorescent sensor array comprises three fluorescent probes, the terbium complexes are respectively a 5-methoxy isophthalic acid-terbium complex, a 5-hexadecyloxy isophthalic acid-terbium complex and a 5-(6 '-cholesterol) hexyloxy isophthalic acid-terbium complex, and the preparation method comprises the following steps: (1) dissolving an aromatic dicarboxylic acid ligand in DMSO (dimethylsulfoxide) to obtain an aromatic dicarboxylic acid ligand mother solution; dissolving a terbium source in distilled water to obtain terbium ion mother liquor; and (2) adding the terbium ion mother liquor into an HEPES buffer solution, adding an aromatic dicarboxylic acid ligand mother liquor into the HEPES buffer solution, and carrying out constant-temperature reaction at 30-40 DEG C for 40-95 minutes to obtain the aromatic dicarboxylic acid-terbium complex. The fluorescent sensor array can be used for detecting tetracycline, cefixime, chloramphenicol and ciprofloxacin, and is high in accuracy and sensitive.

The invention provides double-layer modular thermal response hydrogel as well as a preparation method and application thereof, and belongs to the technical field of hydrogel preparation. The hydrogel is formed by stacking a temperature protection layer and a treatment layer in situ. The phase change temperature of the temperature protection layer can be accurately regulated and controlled, the treatment layer is prepared by mixing a sodium alginate solution, an MXene nanosheet dispersion liquid, a ciprofloxacin solution, delta-glucolactone and calcium carbonate and then cross-linking through calcium chloride, aggregation of MXene and ciprofloxacin due to electrostatic interaction is avoided by utilizing an ordered feeding sequence, and the treatment effect is improved. And uniform dispersion and stability of the components are ensured. The double-layer hydrogel integrates the photothermal effect and the membrane damage capacity of MXene and the chemical sterilization effect of ciprofloxacin, and synergistic and efficient antibiosis is achieved; the temperature protection layer on the upper layer can be repeatedly used, the treatment layer on the lower layer can be modularly replaced, and real-time monitoring and feedback of wound temperature can be achieved through electrical conductivity of MXene.

The invention belongs to the technical field of biology, and particularly relates to a bifidobacterium longum subsp. Longum FMBL B241768LS, a microbial inoculum and application of the microbial inoculum in hypoglycemic products, the bifidobacterium longum subsp. Longum FMBL B241768LS is preserved in China Center for Type Culture Collection on October 14, 2024, and the preservation number is CCTCC NO: M 20242173; the inhibitory activity of the compound on dipeptidyl peptidase IV is as high as 79.17%; the compound has a relatively good inhibition effect on the activity of alpha-glucosidase and alpha-amylase; the compound shows drug resistance to ciprofloxacin, ampicillin, penicillin G, clindamycin, kanamycin and polymyxin B; a good inhibition effect is achieved on pathogenic bacteria; the strain can be used for preparing medicines, fermented foods, health-care products and food additives for reducing blood sugar and inhibiting pathogenic bacteria, and has a wide application prospect.

An embodiment relates to a tablet comprising celecoxib, and ciprofloxacin or a pharma- ceutically acceptable salt thereof, and a low viscosity hydroxypropyl methylcellulose having a viscosity of less than 150 cP when measured as a 2% solution in water at 20°C.

The invention relates to a hypertension implant rod and a preparation method thereof, and relates to the technical field of hypertension implant rods, the hypertension implant rod comprises a quick release layer, a slow release layer and a long-acting regulation and control layer from outside to inside, the quick release layer comprises, by mass, 60-70% of bacterial cellulose (BC), 15-25% of polydopamine (PDA), 3-8% of ciprofloxacin, 3-8% of protamine and 4-6% of indapamide, the slow release layer comprises, by mass, 20-30% of a long-acting regulation and control layer, and the long-acting regulation and control layer comprises, by mass, 20-30% of a slow release layer and 20-30% of a long-acting regulation and control layer. The sustained release layer is prepared from 55 to 65 percent of polylactic acid-glycolic acid copolymer, 20 to 30 percent of cross-linked gelatin, 8 to 12 percent of lacidipine and 4 to 6 percent of spirolactone, and the long-acting regulation and control layer is prepared from 65 to 75 percent of L-polylactic acid, 20 to 30 percent of beta-glycine crystal, 3 to 5 percent of silk fibroin (SF), 0.5 to 1.0 percent of calcitonin gene related peptide CGRP and 0.1 to 0.3 percent of neuropeptide Y. The hypertension implant rod can be matched with various treatment cycles through gradient degradation, realizes'on-demand treatment ', is high in biocompatibility, is suitable for subcutaneous implantation, and is convenient and safe to operate.

The invention belongs to the technical field of microorganisms, and particularly relates to lactobacillus johnsonii with a function of resisting multiple drug-resistant bacterium biological membranes and anti-inflammatory activity and application of the lactobacillus johnsonii. The lactobacillus johnsonii A25041 provided by the invention has strong inhibition and anti-biofilm activity on multi-drug-resistant gram-negative bacteria (including escherichia coli, pseudomonas aeruginosa and acinetobacter baumannii) and methicillin-resistant staphylococcus aureus, and the lactobacillus johnsonii A25041 has good acid-base tolerance and gastrointestinal fluid tolerance, so that the lactobacillus johnsonii A25041 can be used for preparing medicines for preventing and treating various diseases. The composition shows excellent anti-inflammatory activity and oxidation resistance, does not have hemolysis capacity, is good in safety, has natural drug resistance to gentamicin, tetracycline, ciprofloxacin, lincomycin and compound sulfamethoxazole, can be used together with antibiotics at the same time or in sequence, maintains intestinal microecological balance and relieves antibiotic burden while exerting the sterilization effect of the antibiotics, and has a good application prospect. The method can be widely applied to functional food development, and has important application value in the field of biological medicine and daily chemical products.

The application discloses a three-dimensional positive-negative general electrode, which is used for adsorbing organic pollutants and comprises a three-dimensional skeleton and an adsorption functional layer; the three-dimensional skeleton and / or the adsorption functional layer has conductivity; the adsorption functional layer is covered on the surface of the three-dimensional skeleton, and the constituent material of the adsorption functional layer comprises one or more of conductive polymers, biochar and synthetic carbon. The electrode has large adsorption capacity and high mass transfer efficiency, can efficiently capture organic pollutants in wastewater, and overcomes the problems of traditional physical adsorbents, such as easy loss and difficult recovery, and the like; when the electrode is used as a cathode or an anode to adjust and adsorb organic pollutants under the cooperation of an electric control, the electrode has stronger adsorption capacity and enrichment capacity. The application further provides a wastewater treatment system, which can quickly and completely treat wastewater, and provides applications of the three-dimensional positive-negative general electrode and the wastewater treatment system in treatment of organic pollutants, such as oxytetracycline, methylene blue, methyl orange and ciprofloxacin.

The application discloses an embedded N-substituted benzisothiazolinone and N-substituted ciprofloxacin antibacterial polyurethane acrylate film material, and belongs to the field of organic antibacterial coating.The application introduces double bonds into benzisothiazolinone structural units and ciprofloxacin structural units by respectively functionalizing benzisothiazolinone and ciprofloxacin N-substituted alkenyl groups, grafts N-substituted alkenyl functionalized benzisothiazolinone derivatives (NBT) and ciprofloxacin derivatives (NCP) into a polyurethane acrylate main chain at the same time, and utilizes excellent antibacterial properties of NBT on staphylococcus aureus and excellent antibacterial properties of NCP on escherichia coli to prepare a broad-spectrum antibacterial material, and a corresponding antibacterial coating can be used for modifying a substrate surface.

The invention belongs to the technical field of environmental functional materials, and discloses a preparation method and application of an oxygen-vacancy-enriched ferrocobalt spinel and carbon core-shell microreactor. According to the method, a cobalt-iron spinel and carbon core-shell catalyst with rich oxygen vacancies is constructed through a defect engineering and morphology engineering synergistic strategy, and peroxymonosulfate (PMS) is efficiently activated to degrade antibiotics in water. The method specifically comprises the following steps: synthesizing a ferrocobalt spinel-carbon core-shell structure by adopting hydrothermal, metal ion adsorption and pyrolysis processes, and introducing oxygen vacancies through KBH4 reduction to optimize electron transfer and catalytic activity of the ferrocobalt spinel-carbon core-shell structure. The carbon nucleus in the obtained catalyst effectively enriches pollutants and PMS, and the confinement effect shortens the migration path of active oxygen species; and the PMS activation efficiency is obviously improved by the introduced oxygen vacancies. The catalyst is efficient when used for degrading antibiotics such as ciprofloxacin, has the advantages of high reaction rate constant, high removal rate, wide pH adaptability, strong anti-interference capability, low metal leaching and the like, and has a wide application prospect in the field of environmental governance.

The application provides a ciprofloxacin sewage treatment method, comprising the following steps: providing compound sewage containing ciprofloxacin and cadmium, adjusting the pH value of the compound sewage to 2-7, then adding Fe@C composite material, after a period of adsorption reaction, adding potassium persulfate, and continuing to react to remove ciprofloxacin and cadmium in the compound sewage. The method is simple in operation and mild in application conditions, can obviously improve the removal effect of ciprofloxacin in sewage, can simultaneously achieve good treatment effect on cadmium and ciprofloxacin compound pollution, can fill the blank in the related field, can solve the existing actual water body problem, and has practical application significance.