40 results about "Gallate" patented technology

A nutraceutical composition, consisting of Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.

The invention belongs to the technical field of pharmacotherapeutics, and particularly relates to application of theaflavin-3 '-gallate and a medicine prepared from theaflavin-3'-gallate. The theaflavin-3 '-gallate is used as a KEAP1-NRF2 inhibitor and is competitively combined with the KEAP1 to destroy the inhibition effect of the KEAP1 on the NRF2, so that the content of the NRF2 is increased, and the expression of downstream NQO1 and GCLC is improved. Besides, the theaflavin-3 '-gallate protects the liver function by inhibiting the increase of the contents of AST and ALT, and reduces the oxidative stress and lipid accumulation of the liver, so that the theaflavin-3'-gallate has the potential to become a medicine for treating the ethanol-induced liver injury.

The invention belongs to the technical field of medicines, and particularly provides a novel application of a theaflavin compound in preparation of a product for inhibiting dipeptidyl peptidase-4 (DPP-4), and the theaflavin compound is one or more of theaflavin-3-gallate (TF2A), theaflavin-3 '-digallate (TF3) and theaflavin (TF). The research systematically proves that TF2A, TF3 and TF have new application of inhibiting DPP-4 for the first time: in-vitro enzymology and fluorescence experiments show that theaflavin can inhibit DPP-4 and interact with DPP-4, and molecular docking further shows possible binding configuration and key action sites of theaflavin. In vivo, the activity of DPP-4 in serum and different tissues of high-fat diet mice can be reduced, serum glucagon-like peptide-1 (GLP-1) can be up-regulated, and glycometabolism and inflammatory phenotype can be improved. Therefore, the theaflavin compound disclosed by the invention can be applied to preparation of products for inhibiting DPP-4, and has a good development prospect.

The invention discloses a preparation method and application of sodium gallate-polyphenol chitosan antibacterial hydrogel, firstly, gallic acid and sodium acetate are used as raw materials, a high-purity sodium gallate complex 5-carboxyl-2, 3-sodium dihydroxyphenolate is prepared at normal temperature and normal pressure, then a polyphenol compound and chitosan are cross-linked through Schiff base reaction, and the sodium gallate-polyphenol chitosan antibacterial hydrogel is obtained. And finally, carrying out rotary evaporation treatment, so that the sodium gallate is loaded in the polyphenol chitosan hydrogel system to obtain the antibacterial hydrogel. Sodium gallate is used as a functional component, uniform loading of sodium gallate in a polyphenol chitosan hydrogel system is realized through dual effects of physical adsorption and chemical bonding, the loading mechanism can effectively avoid aggregation and burst release of sodium gallate, stable release of antibacterial components is ensured, and the antibacterial property of the hydrogel is improved. The slow release time of the antibacterial hydrogel under the conditions that the pH values are 5.5 and 7.2 respectively exceeds 24 hours; and the antibacterial hydrogel has an inhibition effect on both gram-positive bacteria and gram-negative bacteria.

This invention discloses a method for preparing alkyl gallate without a dehydrating agent, belonging to the field of chemical reaction auxiliary technology. By optimizing the raw material ratio of the reaction system, precisely controlling the reaction environment parameters and the condensate separation rate, this invention utilizes the azeotropic properties of alcohol and water to achieve efficient separation of the water generated in the reaction. It can promote the forward esterification reaction without adding any dehydrating agent, achieving the same or even better water separation and reaction promotion effects without the need for a dehydrating agent. This invention eliminates the need for a dehydrating agent, and the synthesized methyl gallate, ethyl gallate, propyl gallate, octyl gallate, and lauryl gallate can reach a maximum content of 99.2%, with a stable product yield of 50-57g. This effectively reduces production costs, avoids the pollution problems caused by dehydrating agents, simplifies the production process, and possesses both green environmental protection and promising prospects for industrial-scale application.

The invention relates to a preparation process of near-infrared fluorescent powder, in particular to nickel-containing near-infrared fluorescent powder and a preparation method thereof, a certain amount of barium carbonate, gallium oxide, nickel oxide and isopropanol are taken to be prepared into turbid liquid, and the nickel-containing barium gallate-based near-infrared fluorescent powder is prepared through the steps of grinding, drying, grinding, pressing, heat treatment, cooling, grinding and the like. Under the excitation of 635 nm light, the fluorescent powder presents ultra-wide band near-infrared luminescence composed of 1050-1400 nm light emission derived from matrix defects and 1300-1800 nm light emission of Ni < 2 + > ions; the light-emitting diode light source is more suitable for compact special near-infrared fluorescent powder conversion light-emitting diode light source design for high-resolution deep biological tissue imaging diagnosis equipment. Similarly, due to no ionizing radiation ultra-wide band NIR-II region emission, the system can be used in various biological tissue situations such as fat, muscle, endothelium and the like, and then development of multipurpose imaging diagnostic analysis technologies and equipment which are suitable for family daily medical treatment and are friendly and safe to special groups such as children, pregnant women, old people and the like can be promoted.

The invention discloses an ionic liquid transmucosal delivery system based on polyphenol modification. A preparation method comprises the following steps: S1, preparing polyphenol modified ionic liquid by adopting aromatic folic acid, polyphenol A and choline bicarbonate; the polyphenol A is gallic acid or caffeic acid; s2, polyphenol B is dissolved in ultrapure water, a biomacromolecule medicine is added, freeze drying is performed after ultrasonic treatment, and polyphenol-biomacromolecule nanoparticles are obtained; the polyphenol A is epigallocatechin-3-gallate, and the polyphenol B is epigallocatechin-3-gallate or tannic acid; s3, adding the polyphenol-biomacromolecule nanoparticles into the ionic liquid, and performing ultrasonic treatment to obtain the ionic liquid transmucosal delivery system based on polyphenol modification. According to the drug delivery system, polyphenol participates in ionic liquid construction, more intermolecular interaction force sites are provided for the ionic liquid, the charge property of the ionic liquid is reduced, and meanwhile, polyphenol-biomacromolecule nanoparticles are constructed to prolong the in-vivo action time of the drug.

The invention provides an alkyl gallate epoxy curing agent as well as a preparation method and application thereof. The alkyl gallate epoxy curing agent has good corrosion inhibition performance, and can improve the adhesion and antibacterial property of a coating; the coating also has a strong adhesion effect, and the formed coating has an excellent dry adhesion effect; in some cases, based on a good hydrophobic effect given by long-chain alkyl contained in the alkyl gallate epoxy hardener, the alkyl gallate epoxy hardener also has good adhesive force in a high-humidity environment, so that the alkyl gallate epoxy hardener is particularly suitable for being used on equipment in the humid environment such as a marine environment.

The invention belongs to the technical field of crystal form drug molecules, and particularly relates to baricitinib-maleic acid-gallate. After the three components form the salt, the solubility of baricitinib can be remarkably enhanced, the oral bioavailability is improved, and the salt has a very high patent medicine value and a relatively good application prospect in the medical industry.

The invention discloses a theaflavin nano-composite with whitening and moisturizing effects, which is mainly prepared from theaflavin as an active component, an encapsulation carrier and a synergistic component, and has a core-shell structure with theaflavin as a core and a three-dimensional network formed by the encapsulation carrier as a shell, the purity of the theaflavin is not lower than 80%, and the mass ratio of the theaflavin-3-gallate to the theaflavin-3 '-gallate is 1: (0.8-1.2); the encapsulation carrier comprises modified silk fibroin, activated tamarind seed polysaccharide and self-assembly oligopeptide with pH responsiveness, and a three-dimensional network is formed through reaction; the synergistic interaction components are 2-o-ethyl ascorbic acid and eugenol. The invention also discloses a preparation method and application of the compound. The theaflavin nano-composite prepared by the invention has the advantages of high stability, good bioavailability, capability of quickly releasing active matters on the surface of skin in a weakly acidic environment, and realization of whitening and moisturizing effects.

A method of enhancing the quality of a skin scar by topical application of an agent for improving scar quality is characterised in that said agent is pre-emptively applied to a potential surgical cutaneous site in advance of surgery, including surgery involving use of lasers. The topical agent may be a polyphenol, such as (-)-epigallocatechin-3-gallate (EGCG). Use of such a topical agent in advance of surgery leads to significant beneficial effects on dermal scarring by reducing mast cells, angiogenesis, skin thickness and simultaneously increasing elastin content. The topical agent may be applied directly or incorporated in a dressing, such as in a dermal patch comprising an adhesive silicone sheet, and can be worn both in the lead up to surgery and post-operatively.

The application discloses a kind of double ester type catechins compound and preparation method, steps are as follows: tea is mixed with methanol aqueous solution, and tea extract is obtained by ultrasonic extraction;Tea extract is continuously carried out reverse phase liquid chromatography separation, and finally double ester type catechins compound is obtained by collecting specific eluent and the distillate of specific time period, which is obtained epigallocatechin-3,4'-di- O -gallate and gallocatechin-3,4'-di- O -gallate is first purified by separation, and double ester type catechins compound has high purity.

A 3D-printed cervical plug. A 3D-printed cervical plug support is filled with a nanocomposite hydrogel. The nanocomposite hydrogel is a supramolecular nanocomposite formed by self-assembly of (-)-epigallocatechin-3-gallate and metal ions in a hydrogel.

The application discloses an EPA liposome and a preparation method and application thereof, and particularly relates to the technical field of cosmetics. The EPA liposome is prepared through self-assembly of liposomes by using the following raw materials in parts by mass: microalgae oil EPA 1-4 parts, epicatechin-3-gallate 1-2 parts, alpha-tocopherol 0.2-1 part, ginsenoside Rg3 0.02-0.1 part, lipids 2-10 parts, emulsifier 1-10 parts, and water is supplemented to 100 parts. The EPA liposome realizes the stable effect of EPA in a composite system such as a cosmetic skin care product, enhances the in-situ antioxidant and protective functions of EPA and slows down the autoxidation of EPA, improves the bioavailability and enhances the anti-aging effect through the synergy of the contained efficacy substances and the design of the nano-liposome.

A heterogeneous catalytic process for manufacturing alkyl gallates / digallates (e.g., esters of gallic acid) from gallic acid (e.g., 3,4,5-trihydroxy benzoic acid) and corresponding C1-C20 alkyl alcohol / diol in the presence of a non-halogenated, hydrophilic, strong cationic ion exchange resin, with high purity and higher yields. The process is devoid of neutralization and de-colorization steps and is free of toxic solvents and is suitable to synthesize higher alkyl gallates which are otherwise difficult to obtain by conventional methods.

This invention relates to the field of scale inhibition technology, and proposes a scale inhibitor for soda ash mother liquor and its preparation method. The scale inhibitor for soda ash mother liquor comprises the following components by weight: 50-75 parts polyacrylic acid, 30-50 parts polyepoxysuccinic acid, 5-12 parts surfactant, 2-16 parts sodium gallate, 1-10 parts sodium lactate, 1-7 parts stabilizer, 0.5-4.5 parts dispersant, and 30-50 parts water. This technical solution solves the problem of low scale inhibition rate in existing soda ash mother liquor scale inhibitors.

The disclosure relates to crystalline Form X of epigallocatetchin-3-gallate, compositions containing Form X, and methods of using Form X. The disclosure also relates to methods of making crystalline Form X of epigallocatetchin-3-gallate.

The gas-liquid separation condensing device comprises a condensing tower, a trigger switch and an electric control liquid discharge pipe, an exhaust pipe is arranged at the upper end of the condensing tower, a refrigerant inlet pipe and a refrigerant outlet pipe are installed at the upper end and the lower end of the side of the condensing tower respectively, a sleeve is arranged on the outer wall of the upper end of the refrigerant outlet pipe, and the refrigerant inlet pipe and the refrigerant outlet pipe are communicated through a pipeline. An air inlet pipe is arranged at the lower end of the side, away from the refrigerant inlet pipe, of the condensing tower, a trigger switch is mounted on the lower surface of the end of the air inlet pipe in the condensing tower, an electric control liquid discharging pipe is arranged on the surface of the condensing tower below the air inlet pipe, and a square rod is fixedly connected to the inner wall of the lower end of the condensing tower on the side of the electric control liquid discharging pipe. The outer wall of the square rod is sleeved with a floating plate, and a positioning pipe is fixedly installed at the upper end of the square rod. According to the gas-liquid separation condensing device for the amyl gallate reaction, condensate is conveniently prevented from being accumulated on the condensing structure, so that the normal work of the device is prevented from being influenced, and the practicability of the device is improved.

The invention discloses a method for industrially preparing gambiered canton gauze, and solves the problems that the traditional manual dyeing process for producing gambiered canton gauze has strong dependence on natural environmental factors, low mechanization degree and high product cost, and river mud has bacteria and heavy metal pollution hidden dangers. Comprising the following reaction processes: 1) hydrolyzing tannin slurry on the silk fabric to generate gallic acid; 2) reacting the calcium carbonate slurry with gallic acid to generate calcium gallate, water and carbon dioxide, and gradually remaining the calcium gallate in a fiber amorphous region and between fibers to form calcification deposition through hydrogen bonds and Van der Waals force effects between molecules and between the calcium gallate and silk protein fibers; (3) carrying out color development crosslinking on trace iron ions in the color development paste and calcium gallate and fully reacting; and 3) performing esterification cross-linking reaction on residual carboxyl and phenolic hydroxyl in the reaction system in the step 3) in a heating and drying environment to generate low-shrinkage tannin ester and water, and finally forming a calcium gallate and real silk fiber integrated polymolecular cross-linked polymer, namely the gambiered canton gauze.

The embodiment of the invention provides a skin care composition as well as a preparation method and application thereof, the skin care composition comprises alkyl gallate, tryptophan and mannitol, and the concentration of the alkyl gallate is 0.1 mu mol / L-4 mmol / L. The skin care composition can be prepared into skin care compositions in various dosage forms, is used for skin care and repair, has the effects of sunscreen, anti-inflammation, wrinkle removal and the like, and is simple and convenient to prepare, safe, high in yield and suitable for industrial production.

The invention discloses application of hempseed (-)-epicatechin-3-O-gallate, and belongs to the technical field of biology. According to the invention, the EPI (-)-epicatechin-3-O-gallate extracted from the EPI is applied to the diabetic kidney diseases, so that the EPI can significantly reduce blood sugar and blood fat levels, improve pathological changes of the kidney of diabetic mice, delay senescence and fibrosis of renal tubular epithelial cells of the diabetic mice, improve the drug efficacy of DKD (Dikyl Ketene Dimer), and can be used for treating the diabetic kidney diseases. And reliable treatment targets and theoretical basis are provided for treating DKD by natural medicine monomer components.

This invention discloses gallic acid-based MOF gas-sensitive materials, their preparation methods, and applications. The preparation method of the gallic acid-based MOF gas-sensitive material includes the following steps: dissolving a metal salt and gallic acid in an alkaline solution and reacting them at 110-150°C to obtain the gallic acid-based MOF gas-sensitive material; the metal salt is selected from one or more of the nitrates, sulfates, and hydrochlorides of cobalt, magnesium, and nickel; the molar ratio of the metal salt to gallic acid is 1:(1.5-2.5). This invention uses the gallic acid-based MOF gas-sensitive material to prepare QCM gas sensors, especially QCM-type ammonia sensors. Compared with Mg-Gallate MOF-based and Ni-Gallate MOF-based QCM gas sensors, the Co-Gallate MOF-based QCM gas sensor exhibits superior selectivity and good sensitivity for ammonia.

The invention discloses a magnesium gallate avalanche detector and a preparation method thereof. The magnesium gallate avalanche detector comprises an Nb: STO layer, an MgO: Al layer and an MgGa2O4 layer which are sequentially arranged from bottom to top, wherein the Nb: STO layer and the MgGa2O4 layer are respectively led out through a first electrode and a second electrode. After Al is doped with MgO, lattice distortion can be formed, the electron-phonon interaction is enhanced, photon absorption by phonon vibration is promoted, and the MgO: Al optical band gap is increased; secondly, Al doping can change the Fermi level position on the surface of MgO, so that the bottom energy of a conduction band on the surface of MgO is increased, and the band gap of MgO: Al is indirectly increased; for an avalanche detector, the dark current of the device can be reduced.

A nutraceutical composition, consisting of Nicotinamide Riboside in a range of 100-2000 mg or Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.

A topical formulation is provided for treating systems of radiation treatments that includes a moisturizer base, and a plurality of active ingredients that include a corticosteroid, silymarin, and epigallocatechin-3-gallate (EGCG).

The present invention discloses a Cu ion-doped gallate-based luminescent material that can be excited by visible light and a preparation method thereof, belonging to the technical field of luminescent materials. The chemical formula of the luminescent material of the present invention is: Sr 1‑x Ga2O4:xCu 2+ , wherein x is 0.5% to 4%. When the doping amount of x is 2%, the sample can be excited by visible light, and the sample can exhibit green broadband emission of 450 to 600 nm when excited by ultraviolet light, with the main emission peak wavelength being around 530 nm; after the ultraviolet light is turned off, a green afterglow in the above-mentioned band and an orange afterglow with a wavelength of 550 to 650 nm appear, wherein the main emission peak wavelength of the orange afterglow is around 610 nm; the green afterglow is relatively short-lived, and after the green afterglow disappears, a longer orange afterglow is finally exhibited; the luminescent material of the present invention can be excited by visible light and LED lights; at the same time, it also has the advantages of stable performance, high luminous efficiency, simple and safe preparation method, pollution-free and low cost.

The invention provides an application of epigallocatechin-3-gallate in preparation of an acute respiratory distress syndrome product. The epigallocatechin-3-gallate can be used for treating acute respiratory distress syndrome. According to the application disclosed by the invention, the ARDS induced by lipopolysaccharide is treated by utilizing the epigallocatechin-3-gallate and improving intestinal microorganisms and metabolite short-chain fatty acid, and a new way is opened up for the treatment of the ARDS.

An automatic dishwashing composition is provided, comprising: a builder; a nonionic surfactant; a dispersant polymer, wherein the dispersant polymer comprises < 1 wt%, based on weight of the dispersant polymer, of structural units of sulfonated monomer; gallic acid (salt); and, optionally, a filler.

The invention discloses a reslurrable organic silicon waterproof and oil-proof coating as well as a preparation method and application thereof, and belongs to the technical field of new organic silicon materials. The preparation method comprises the following steps: preparing amino silicon oil by taking methylcyclosiloxane, N-beta-aminoethyl-gamma-aminopropyl methyl dimethoxy silane and tetramethyl amine hydroxide as raw materials; performing epoxidation on the alkyl gallate to prepare alkyl gallate epoxy; the surface of paper is coated with amino silicon oil and alkyl gallate epoxy in a roller coating mode, and the waterproof and oil-proof coating of the paper is prepared through the ring-opening reaction of epoxy and amino. After paper is coated with the waterproof and oil-proof coating, the waterproof and oil-proof coating can be directly used as food packaging paper, the conventional waterproof and oil-proof effect can be achieved, hot water and hot oil contact scenes can be better resisted, the excellent repulping recycling performance is achieved, after the packaging use period is completed, fiber recycling can be achieved through a conventional papermaking repulping process, and the production cost is reduced. Environmental burden caused by difficult degradation and incapability of recycling is avoided, and resource recycling in the packaging industry is facilitated.