114 results about "Dermal patch" patented technology

In one embodiment, the present invention provides a device, wherein the device comprises a skin patch, configured to attach to the skin surface of the perineum of a subject suffering from premature ejaculation, wherein the skin patch contains electrodes configured to deliver electrical impulses transcutaneously to the bulbcavernosus muscle of the subject, wherein the transcutaneously delivered electrical impulses are configured to treat premature ejaculation.

A method for the custom production of a skin patch for the purpose of hair thickening according to the scalp shape of a patient, the method comprising the main steps of: a) drawing an image of the patient, collecting all information by 3D scanning and drawing an image of the patient to create a digital copy of the patient (digital replica), a template structure is generated through 3D printing; b) providing a template for processing, comprising the application of a preferred compact elastic polyurethane; c) applying the hair by approaching the hair to a template connected to a suction system: sucking the hair into the special hole; heating the polymer film to near the melting point, incorporating the hair therein to achieve the desired natural hair effect; and cooling.

The invention discloses a multi-modal intelligent skin patch for multi-scene cardiopulmonary function monitoring and a use method thereof. The multi-modal intelligent skin patch comprises a layered structure body, a flexible circuit board, a multi-modal sensing assembly, a power management assembly and a wireless communication module. The layered structure body comprises an upper Ecoflex material layer, a lower Ecoflex material layer, a lithium battery and a wireless charging coil, wherein the lithium battery and the wireless charging coil are packaged between the two Ecoflex material layers. A layered structure in which the upper Ecoflex material layer and the lower Ecoflex material layer package the lithium battery and the wireless charging coil is adopted, and a polyimide flexible circuit board and a double-bridge snake-shaped structure sensing wire are combined, so that the equipment is endowed with excellent tensile tolerance and skin fitting property; in cooperation with the sweat-proof adhesiveness of the 3M2477P medical silica gel double-faced adhesive tape and the high conductivity of the high-adhesiveness conductive hydrogel layer, the problems of electrode falling and signal distortion caused by sweating and skin stretching in violent activities such as high-intensity intermittent movement are fundamentally solved, and stable acquisition of electrocardio, PPG and respiratory wave signals is ensured.

A dermal patch system for administering a pharmaceutical includes a vial that stores a pharmaceutical and a cartridge coupled to the vial. The cartridge includes a pull mechanism, a pump, a plurality of microneedles in communication with the vial. The microneedles are configured to move between an undeployed position to a deployed position. When pulled, the pull mechanism is configured to cause the microneedles to move from the undeployed position to the deployed position and cause the pump to pump the pharmaceutical from the vial and to the microneedles.

The invention provides a physical manipulation apparatus that is engageable with a skin surface of a human or animal subject. The apparatus may include a skin-engageable pad configured to conform to the morphology of a physical manipulation member such as a digit of a human therapist or a stylus tip of a chiropractic adjustment instrument. The skin-engageable pad may include a friction-inducing component in the form of a biomimetic dry adhesive. The apparatus may include a digit cover (110, 120, 130) configured at least partially to cover a human digit. Instead, the apparatus may be configured as a skin patch having two release liners superimposed, respectively, on opposite sides of the skin-engageable pad. The skin patch may include indicia arranged to indicate a required orientation of the skin patch relative to a targeted anatomical feature such as a spinal segment, or a required direction of movement of the manipulation member.

A system for analyzing a physiological sample includes a cartridge configured to attach to the skin of a subject. The cartridge includes: a processing fluid pack that is configured to release a processing fluid stored therein, a diagnostic test strip, and a vacuum pin. The system also includes a lancet with a needle. The lancet is configured to deploy the needle upon engagement with the cartridge to draw a physiological sample from the subject. The vacuum pin is configured to create a vacuum within the cartridge to draw the released processing fluid and the drawn physiological sample to the diagnostic test strip.

The invention relates to the field of biomedical materials, and discloses a flexible photoelectric skin patch which is composed of a vertical amorphous silicon radial junction PIN structure photoelectric unit and a flexible transparent substrate. The preparation method of the flexible photoelectric skin patch mainly comprises the following steps: growing amorphous silicon radial junction nanowires on an oxidized silicon wafer substrate through a gas-liquid-solid (VLS) mechanism, then integrally transferring the amorphous silicon radial junction nanowires to the surface of a flexible and transparent substrate to obtain the flexible photoelectric patch which can be attached to the surface of skin in a shape-preserving manner, and accelerating the repair of a skin wound under illumination. The photoelectric device is prepared by adopting a low-temperature growth process, the cost is low, the preparation is simple, and the outstanding three-dimensional structure endows the device with excellent flexibility.

The invention discloses a robot electronic skin patch system and a preparation method and application thereof, and relates to the technical field of robot electronic skin patch systems, and the robot electronic skin patch system comprises a flexible sensor and a signal acquisition and processing system. The flexible sensor comprises a first electrode layer, a second electrode layer and an elastic dielectric layer. The elastic dielectric layer is arranged between the first electrode layer and the second electrode layer and comprises an elastic dielectric component with a three-dimensional structure, and the elastic dielectric component can deform under the action of longitudinal pressure. According to the invention, the function of measuring the bending angle is added on the sensing assembly with the three-layer structure and the pressure measuring function, and real-time angle monitoring at the joint of the robot arm is realized. The electrodes on the same electrode layer can be independent of a sensing circuit, generated electric signals are transmitted to a signal acquisition system through respective leads, and the signals are processed and analyzed to obtain pressure and angle data. The robot electronic skin patch system is high in integration level, weak in signal crosstalk and high in measurement precision.

A functional ceramic polymer active ingredient composite containing a microcurrent self-generation material, a skin patch using same, a manufacturing method therefor, and a use method therefor are provided. The functional ceramic polymer active ingredient composite can be prepared through: a first stirring step of stirring a solvent and a formulation material for composite production, thereby forming a fluid liquid formulation material; a second stirring step of forming a ceramic polymer composite by stirring the liquid formulation material and a ceramic powder, which produces energy; and a third stirring step of stirring the ceramic polymer composite and an active ingredient material.

The invention discloses an intelligent skin attaching device, and relates to the technical field of intelligent wearing, the intelligent skin attaching device comprises a fixing assembly, a patch assembly, a first limiting structure and a second limiting structure, the fixing assembly is used for being adsorbed on the skin; the patch assembly is detachably connected with the fixing assembly; the first limiting structure is arranged between the fixing assembly and the patch assembly, so that after the patch assembly is installed on the fixing assembly, the patch assembly is limited to move relative to the fixing assembly in the first direction, and the patch assembly is prevented from being away from the skin side; the second limiting structure is arranged between the fixing assembly and the patch assembly, so that after the patch assembly is installed on the fixing assembly, the patch assembly is limited to move relative to the fixing assembly in the second direction, and limiting failure of the first limiting structure is avoided. According to the technical scheme provided by the invention, the connection reliability of the fixing assembly and the patch assembly is improved, and the use reliability of the intelligent skin pasting equipment is improved.

The application discloses a blood glucose monitoring device and method capable of realizing continuous blood glucose monitoring and control. The monitoring method comprises the following steps: regulating the subcutaneous penetration state of insulin by changing the direction of an electric field applied to an insulin gel composition; wherein the insulin gel composition is communicated with a microneedle array composed of hollow microneedles, and the insulin gel composition comprises insulin, hyaluronic acid and a hydrogel. The application can realize automatic and continuous blood glucose monitoring and dynamic insulin regulation, and can be designed in the form of a skin patch for application by a patient, and has the advantages of small volume, high comfort and low cost.

The present invention relates to a flexible skin patch equipped with an ultra-thin LED assembly that emits light in a specific wavelength range and an invention for manufacturing the same, and is related to an invention capable of providing a flexible skin patch that has the excellent effect of promoting vitamin D production in a localized area of the skin, and has the effect of alleviating or treating local skin psoriasis, fungi, fungal tumors and eczema, and has excellent antiviral effect, and is easy to attach and detach.

The invention discloses portable infusion equipment with an early warning function and a monitoring system. The equipment comprises an openable fixing ring, an eccentric wheel / cam extrusion adjusting assembly, a disposable LC resonance sensing short pipe section, a reading coil, a processing unit and a normally closed emergency pinch-off mechanism. The fixing ring sleeves and clamps the infusion hose, and the motor drives the extrusion part to continuously change the through-flow section of the hose; the reading coil and the disposable LC sensor are in non-contact coupling frequency sweeping to read resonance characteristics, the processing unit converts the resonance characteristics into pressure / flow and carries out closed-loop control, and in-place identification and automatic calibration are achieved. The system integrates bubble detection, blockage judgment and slow release strategy and dual-channel flow consistency calibration; and extravasation early warning can be realized through micro pinch-off pulse and pressure response fitting, and the reliability is improved in cooperation with skin patch signal fusion. The device is linked with a mobile terminal and a cloud platform through a wireless module to realize remote monitoring and alarm pushing.

Proposed is a self-current-generating skin-applicable patch with a first area in contact with the skin and a second area adjacent to and spaced apart from it, where either area contains a biodegradable metal, decomposable and absorbable through skin contact or reaction with tissue moisture. The patch includes a first electrode layer directly contacts the skin as a thin sheet integrated with the first area and has at least one fluid-transferable penetration part, a second electrode layer of a material with a different standard reduction potential is positioned opposite a skin-contacting side, partially extending to connect electrically to the second area, and a support layer, a hydrophilic sheet of predetermined thickness, is positioned opposite the skin-contacting side, having an ionic solution supported. Thus, sufficient iontophoresis and other micro-current effects with active ingredients are achieved through self-generated micro-current, even without a battery-like external power source.

The invention relates to the technical field of medical intelligent decision making, in particular to a multi-parameter sensing and repairing process monitoring method for an absorbable biological material. State parameters such as the temperature, the pH value, the stress, the strain and the conductivity of the absorbable biological material are collected in real time through the skin patch sensor and the implantable biocompatible sensor, different stages of the repair process can be accurately recognized in combination with data processing and analysis, the repair process can be effectively optimized, the repair effect can be improved, and the repair cost can be reduced. A potential problem caused by an inaccurate repairing process is avoided; multi-sensor data acquisition and efficient data fusion technologies are adopted, the degradation process and tissue repair conditions of the repair material are accurately mastered through multi-dimensional monitoring, the conditions of abnormal degradation or local instability and the like of the repair material are found in time, it is ensured that the degradation process of the repair material is accurately controlled, and the repair effect is guaranteed to the maximum extent.

In one embodiment, the present invention provides a device, wherein the device comprises a skin patch, configured to attach to the skin surface of the perineum of a subject suffering from premature ejaculation, wherein the skin patch contains electrodes configured to deliver electrical impulses transcutaneously to the bulbcavernosus muscle of the subject, wherein the transcutaneously delivered electrical impulses are configured to treat premature ejaculation.

The present disclosure describes a dermal patch including at least a support layer and a medicament depot including a medicament. The dermal patch is configured to support, protect, and / or medicate a wound during a healing process.

The invention discloses an intelligent skin attaching device, and relates to the technical field of intelligent wearing, the intelligent skin attaching device comprises a fixed seat and a patch body, the fixed seat comprises at least one mounting structure, the mounting structure is provided with a plurality of step positions, and the step positions are used for facing the skin; the patch body is provided with a contact end used for being in contact with the skin, the contact end is provided with an information detection element, the information detection element is used for being in contact with the skin to detect human body information, the patch body is movably installed on the fixing base, and the patch body comprises at least one lap joint part; when the lap joint part is in lap joint with the different step positions of the installation structure, the contact pressure between the contact end and the skin is different. According to the technical scheme provided by the invention, the application range of the patch scheme is expanded through the intelligent skin pasting equipment, the contact pressure can be actively and flexibly regulated and controlled, and the accuracy of signal acquisition, monitoring and the like is improved.

Unit dosage forms, devices, and kits for topical delivery of topical immunosensitizers are provided. These include dermal patches, glass swabs, and kits containing a dermal patch and a glass swab. Among other advantages, the unit dosage forms, devices, and kits presented herein deliver a more consistent and controlled volume of drug solution, prevent underdosing and overdosing, prevent or discourage repeat dosing, and provide a more consistent skin area to which the drug solution is applied.

A polyester copolymer, a method for preparing the polyester copolymer, an adhesive comprising the polyester copolymer, a skin patch comprising the adhesive, and a medical device comprising the adhesive are disclosed. The polyester copolymer comprises the following reaction products: a first diol and a second diol, wherein the first diol is an oligomer, polymer, or copolymer, and the second diol is a short-chain diol having 2 to 20 carbon atoms; a bifunctional compound comprising a dicarboxylic acid, a dicarboxylic acid halide, an anhydride, or a diester; and a third diol, wherein the third diol comprises a branched hydrocarbon group.

This adhesive skin patch contains an aromatic component.

The device 100 comprises hollow microneedles 106 and a substrate 102 that uses capillary action to extract interstitial fluid (ISF) from the skin of the user. The ISF is analysed by an electrochemical

A dermal patch for collecting a physiological sample includes a housing with a collection chamber, a sample channel and a pin within a receptacle of the housing. The sample channel is configured to direct a physiological sample drawn from a subject to the collection chamber. The pin is removably positioned within the receptacle and is configured to move from an undeployed position to a deployed position. The pin is configured to seal the receptacle when in the undeployed position and is further configured to facilitate generation of negative pressure in the sample channel when the pin is moved from the undeployed to the deployed position.

A novel treatment method is disclosed, wherein a patch configured to be placed on a patient's skin is activated, before placement, to deliver localized radiotherapy to a diseased area of the skin. The disclosed devices and methods minimize or prevent collateral damage to the neighboring tissues. In most cases, the disclosed devices and methods include coating a contoured, solid, flexible or conformal substrate with one or more lanthanide elements and then activating (e.g. neutron irradiation) the elements such that its resulting radioisotope emits beta-particles into the diseased skin surface when applied to the patient's skin. Novel processes are described for fabricating and irradiating the lanthanide-based skin patch, for example a holmium-based skin patch.

The application relates to the technical field of medical intelligent decision-making, in particular to a repair process monitoring method of absorbable biomaterials; the application realizes real-time collection of state parameters such as temperature, pH value, stress, strain and conductivity of the absorbable biomaterials through skin patch sensors and implantable biocompatible sensors, and can accurately identify different stages of the repair process in combination with data processing and analysis, can effectively optimize the repair process, improve the repair effect, and avoid potential problems caused by inaccurate repair progress; the application adopts multi-sensor data collection and efficient data fusion technology, accurately masters the degradation process of the repair material and the tissue repair condition through multi-dimensional monitoring, timely discovers abnormal degradation or local instability of the repair material, and ensures that the degradation process of the repair material is accurately controlled, and the repair effect is maximally ensured.

A method of enhancing the quality of a skin scar by topical application of an agent for improving scar quality is characterised in that said agent is pre-emptively applied to a potential surgical cutaneous site in advance of surgery, including surgery involving use of lasers. The topical agent may be a polyphenol, such as (-)-epigallocatechin-3-gallate (EGCG). Use of such a topical agent in advance of surgery leads to significant beneficial effects on dermal scarring by reducing mast cells, angiogenesis, skin thickness and simultaneously increasing elastin content. The topical agent may be applied directly or incorporated in a dressing, such as in a dermal patch comprising an adhesive silicone sheet, and can be worn both in the lead up to surgery and post-operatively.

The present invention relates to modified peanut protein extracts for use in the prevention, reduction, or treatment of peanut allergy in a human wherein said use comprises exposing said human to an initial dose of said peanut protein extract of less than 0.1 µg followed by multiple increasing dosages up to 750 µg peanut protein extract, and wherein said peanut protein extract protein extract preferably a reduced and subsequently alkylated peanut protein extract. The present modified peanut protein extracts can be formulated as a pharmaceutical composition, a beverage, a food product, a toothpaste, a skin patch, a band aid, a mouth wash, a candy, a skin crème, a tablet, a lozenge, a food supplement, a foodstuff or combinations thereof.

Methods and items useful at least therein are provided for IBS related testing and treatment. Disclosed is a patch useful in determining if one or more test materials can cause allergic contact dermatitis in a patient. A kit containing information on use and that may include such a patch and / or test material(s) is also disclosed. A method of IBS related testing including performing skin patch testing on a patient presenting IBS symptoms using at least one test material that can cause allergic contact dermatitis is provided. A method for the treatment of IBS which includes limiting the intake by a patient presenting IBS symptoms of at least one material that gives a positive skin patch test result in the patient is also disclosed.

A patch tape includes a substrate layer in contact with a carrier sheet, an adhesive layer containing an active ingredient for skin and an adhesive, and a barrier layer located between the substrate layer and the adhesive layer and having a thickness of less than 5 μm. The patch tape is attached to the skin after the release sheet is peeled from the adhesive layer. The 180° peeling strength according to JIS Z 0237:2009 between the carrier sheet and the substrate layer is 550 mN / 25 mm or less. In the patch tape, the tensile elongation at break according to JIS K 7161-1:2014 is 130% or more.

In one aspect, a dermal patch is disclosed, which comprises at least a pair of sensing units each configured for detecting at least one analyte in a physiological sample, at least one microneedle configured for puncturing the skin to allow collection of the physiological sample, and a selector device for selecting any one of said sensing units for receiving at least a portion of said collected physiological sample for analysis thereof.