69 results about "Dermal patch" patented technology

The invention discloses a multi-modal intelligent skin patch for multi-scene cardiopulmonary function monitoring and a use method thereof. The multi-modal intelligent skin patch comprises a layered structure body, a flexible circuit board, a multi-modal sensing assembly, a power management assembly and a wireless communication module. The layered structure body comprises an upper Ecoflex material layer, a lower Ecoflex material layer, a lithium battery and a wireless charging coil, wherein the lithium battery and the wireless charging coil are packaged between the two Ecoflex material layers. A layered structure in which the upper Ecoflex material layer and the lower Ecoflex material layer package the lithium battery and the wireless charging coil is adopted, and a polyimide flexible circuit board and a double-bridge snake-shaped structure sensing wire are combined, so that the equipment is endowed with excellent tensile tolerance and skin fitting property; in cooperation with the sweat-proof adhesiveness of the 3M2477P medical silica gel double-faced adhesive tape and the high conductivity of the high-adhesiveness conductive hydrogel layer, the problems of electrode falling and signal distortion caused by sweating and skin stretching in violent activities such as high-intensity intermittent movement are fundamentally solved, and stable acquisition of electrocardio, PPG and respiratory wave signals is ensured.

The invention provides a physical manipulation apparatus that is engageable with a skin surface of a human or animal subject. The apparatus may include a skin-engageable pad configured to conform to the morphology of a physical manipulation member such as a digit of a human therapist or a stylus tip of a chiropractic adjustment instrument. The skin-engageable pad may include a friction-inducing component in the form of a biomimetic dry adhesive. The apparatus may include a digit cover (110, 120, 130) configured at least partially to cover a human digit. Instead, the apparatus may be configured as a skin patch having two release liners superimposed, respectively, on opposite sides of the skin-engageable pad. The skin patch may include indicia arranged to indicate a required orientation of the skin patch relative to a targeted anatomical feature such as a spinal segment, or a required direction of movement of the manipulation member.

The invention discloses a robot electronic skin patch system and a preparation method and application thereof, and relates to the technical field of robot electronic skin patch systems, and the robot electronic skin patch system comprises a flexible sensor and a signal acquisition and processing system. The flexible sensor comprises a first electrode layer, a second electrode layer and an elastic dielectric layer. The elastic dielectric layer is arranged between the first electrode layer and the second electrode layer and comprises an elastic dielectric component with a three-dimensional structure, and the elastic dielectric component can deform under the action of longitudinal pressure. According to the invention, the function of measuring the bending angle is added on the sensing assembly with the three-layer structure and the pressure measuring function, and real-time angle monitoring at the joint of the robot arm is realized. The electrodes on the same electrode layer can be independent of a sensing circuit, generated electric signals are transmitted to a signal acquisition system through respective leads, and the signals are processed and analyzed to obtain pressure and angle data. The robot electronic skin patch system is high in integration level, weak in signal crosstalk and high in measurement precision.

The invention discloses an intelligent skin attaching device, and relates to the technical field of intelligent wearing, the intelligent skin attaching device comprises a fixing assembly, a patch assembly, a first limiting structure and a second limiting structure, the fixing assembly is used for being adsorbed on the skin; the patch assembly is detachably connected with the fixing assembly; the first limiting structure is arranged between the fixing assembly and the patch assembly, so that after the patch assembly is installed on the fixing assembly, the patch assembly is limited to move relative to the fixing assembly in the first direction, and the patch assembly is prevented from being away from the skin side; the second limiting structure is arranged between the fixing assembly and the patch assembly, so that after the patch assembly is installed on the fixing assembly, the patch assembly is limited to move relative to the fixing assembly in the second direction, and limiting failure of the first limiting structure is avoided. According to the technical scheme provided by the invention, the connection reliability of the fixing assembly and the patch assembly is improved, and the use reliability of the intelligent skin pasting equipment is improved.

The application discloses a blood glucose monitoring device and method capable of realizing continuous blood glucose monitoring and control. The monitoring method comprises the following steps: regulating the subcutaneous penetration state of insulin by changing the direction of an electric field applied to an insulin gel composition; wherein the insulin gel composition is communicated with a microneedle array composed of hollow microneedles, and the insulin gel composition comprises insulin, hyaluronic acid and a hydrogel. The application can realize automatic and continuous blood glucose monitoring and dynamic insulin regulation, and can be designed in the form of a skin patch for application by a patient, and has the advantages of small volume, high comfort and low cost.

The present invention relates to a flexible skin patch equipped with an ultra-thin LED assembly that emits light in a specific wavelength range and an invention for manufacturing the same, and is related to an invention capable of providing a flexible skin patch that has the excellent effect of promoting vitamin D production in a localized area of the skin, and has the effect of alleviating or treating local skin psoriasis, fungi, fungal tumors and eczema, and has excellent antiviral effect, and is easy to attach and detach.

The invention discloses portable infusion equipment with an early warning function and a monitoring system. The equipment comprises an openable fixing ring, an eccentric wheel / cam extrusion adjusting assembly, a disposable LC resonance sensing short pipe section, a reading coil, a processing unit and a normally closed emergency pinch-off mechanism. The fixing ring sleeves and clamps the infusion hose, and the motor drives the extrusion part to continuously change the through-flow section of the hose; the reading coil and the disposable LC sensor are in non-contact coupling frequency sweeping to read resonance characteristics, the processing unit converts the resonance characteristics into pressure / flow and carries out closed-loop control, and in-place identification and automatic calibration are achieved. The system integrates bubble detection, blockage judgment and slow release strategy and dual-channel flow consistency calibration; and extravasation early warning can be realized through micro pinch-off pulse and pressure response fitting, and the reliability is improved in cooperation with skin patch signal fusion. The device is linked with a mobile terminal and a cloud platform through a wireless module to realize remote monitoring and alarm pushing.

Proposed is a self-current-generating skin-applicable patch with a first area in contact with the skin and a second area adjacent to and spaced apart from it, where either area contains a biodegradable metal, decomposable and absorbable through skin contact or reaction with tissue moisture. The patch includes a first electrode layer directly contacts the skin as a thin sheet integrated with the first area and has at least one fluid-transferable penetration part, a second electrode layer of a material with a different standard reduction potential is positioned opposite a skin-contacting side, partially extending to connect electrically to the second area, and a support layer, a hydrophilic sheet of predetermined thickness, is positioned opposite the skin-contacting side, having an ionic solution supported. Thus, sufficient iontophoresis and other micro-current effects with active ingredients are achieved through self-generated micro-current, even without a battery-like external power source.

The present disclosure describes a dermal patch including at least a support layer and a medicament depot including a medicament. The dermal patch is configured to support, protect, and / or medicate a wound during a healing process.

The invention discloses an intelligent skin attaching device, and relates to the technical field of intelligent wearing, the intelligent skin attaching device comprises a fixed seat and a patch body, the fixed seat comprises at least one mounting structure, the mounting structure is provided with a plurality of step positions, and the step positions are used for facing the skin; the patch body is provided with a contact end used for being in contact with the skin, the contact end is provided with an information detection element, the information detection element is used for being in contact with the skin to detect human body information, the patch body is movably installed on the fixing base, and the patch body comprises at least one lap joint part; when the lap joint part is in lap joint with the different step positions of the installation structure, the contact pressure between the contact end and the skin is different. According to the technical scheme provided by the invention, the application range of the patch scheme is expanded through the intelligent skin pasting equipment, the contact pressure can be actively and flexibly regulated and controlled, and the accuracy of signal acquisition, monitoring and the like is improved.

Unit dosage forms, devices, and kits for topical delivery of topical immunosensitizers are provided. These include dermal patches, glass swabs, and kits containing a dermal patch and a glass swab. Among other advantages, the unit dosage forms, devices, and kits presented herein deliver a more consistent and controlled volume of drug solution, prevent underdosing and overdosing, prevent or discourage repeat dosing, and provide a more consistent skin area to which the drug solution is applied.

A polyester copolymer, a method for preparing the polyester copolymer, an adhesive comprising the polyester copolymer, a skin patch comprising the adhesive, and a medical device comprising the adhesive are disclosed. The polyester copolymer comprises the following reaction products: a first diol and a second diol, wherein the first diol is an oligomer, polymer, or copolymer, and the second diol is a short-chain diol having 2 to 20 carbon atoms; a bifunctional compound comprising a dicarboxylic acid, a dicarboxylic acid halide, an anhydride, or a diester; and a third diol, wherein the third diol comprises a branched hydrocarbon group.

This adhesive skin patch contains an aromatic component.

A dermal patch for collecting a physiological sample includes a housing with a collection chamber, a sample channel and a pin within a receptacle of the housing. The sample channel is configured to direct a physiological sample drawn from a subject to the collection chamber. The pin is removably positioned within the receptacle and is configured to move from an undeployed position to a deployed position. The pin is configured to seal the receptacle when in the undeployed position and is further configured to facilitate generation of negative pressure in the sample channel when the pin is moved from the undeployed to the deployed position.

The application relates to the technical field of medical intelligent decision-making, in particular to a repair process monitoring method of absorbable biomaterials; the application realizes real-time collection of state parameters such as temperature, pH value, stress, strain and conductivity of the absorbable biomaterials through skin patch sensors and implantable biocompatible sensors, and can accurately identify different stages of the repair process in combination with data processing and analysis, can effectively optimize the repair process, improve the repair effect, and avoid potential problems caused by inaccurate repair progress; the application adopts multi-sensor data collection and efficient data fusion technology, accurately masters the degradation process of the repair material and the tissue repair condition through multi-dimensional monitoring, timely discovers abnormal degradation or local instability of the repair material, and ensures that the degradation process of the repair material is accurately controlled, and the repair effect is maximally ensured.

A method of enhancing the quality of a skin scar by topical application of an agent for improving scar quality is characterised in that said agent is pre-emptively applied to a potential surgical cutaneous site in advance of surgery, including surgery involving use of lasers. The topical agent may be a polyphenol, such as (-)-epigallocatechin-3-gallate (EGCG). Use of such a topical agent in advance of surgery leads to significant beneficial effects on dermal scarring by reducing mast cells, angiogenesis, skin thickness and simultaneously increasing elastin content. The topical agent may be applied directly or incorporated in a dressing, such as in a dermal patch comprising an adhesive silicone sheet, and can be worn both in the lead up to surgery and post-operatively.

The present invention relates to modified peanut protein extracts for use in the prevention, reduction, or treatment of peanut allergy in a human wherein said use comprises exposing said human to an initial dose of said peanut protein extract of less than 0.1 µg followed by multiple increasing dosages up to 750 µg peanut protein extract, and wherein said peanut protein extract protein extract preferably a reduced and subsequently alkylated peanut protein extract. The present modified peanut protein extracts can be formulated as a pharmaceutical composition, a beverage, a food product, a toothpaste, a skin patch, a band aid, a mouth wash, a candy, a skin crème, a tablet, a lozenge, a food supplement, a foodstuff or combinations thereof.

Methods and items useful at least therein are provided for IBS related testing and treatment. Disclosed is a patch useful in determining if one or more test materials can cause allergic contact dermatitis in a patient. A kit containing information on use and that may include such a patch and / or test material(s) is also disclosed. A method of IBS related testing including performing skin patch testing on a patient presenting IBS symptoms using at least one test material that can cause allergic contact dermatitis is provided. A method for the treatment of IBS which includes limiting the intake by a patient presenting IBS symptoms of at least one material that gives a positive skin patch test result in the patient is also disclosed.

A patch tape includes a substrate layer in contact with a carrier sheet, an adhesive layer containing an active ingredient for skin and an adhesive, and a barrier layer located between the substrate layer and the adhesive layer and having a thickness of less than 5 μm. The patch tape is attached to the skin after the release sheet is peeled from the adhesive layer. The 180° peeling strength according to JIS Z 0237:2009 between the carrier sheet and the substrate layer is 550 mN / 25 mm or less. In the patch tape, the tensile elongation at break according to JIS K 7161-1:2014 is 130% or more.

In one aspect, a dermal patch is disclosed, which comprises at least a pair of sensing units each configured for detecting at least one analyte in a physiological sample, at least one microneedle configured for puncturing the skin to allow collection of the physiological sample, and a selector device for selecting any one of said sensing units for receiving at least a portion of said collected physiological sample for analysis thereof.

A device for collecting a physiological sample from a subject includes a lancet with a needle that is configured to puncture the subject's skin and a cartridge configured to engage with the lancet. The lancet is configured to transition the needle from an undeployed position to a deployed position in response to engagement with the cartridge, thereby allowing the needle to puncture the subject's skin.

To provide devices and methods for electrical modulation of nervous tissue.SOLUTION: Devices, systems and methods are described for providing muscle contraction stimulation therapy to treat myriad diseases, including heart failure, Type 2 diabetes and peripheral vascular disease using a skin patch or implantable stimulator that includes a multiplicity of electrodes, a processor 13, a stimulation circuit, one or more sensors 15, and programming for a patient interface unit 16, where the processor is programmed to control selection of a subset of the multiplicity of electrodes and of the operation of the stimulation circuit responsive to an indication of an adverse physiologic response. The indication of patient discomfort may be determined by monitoring the physiologic parameter of the subject using the one or more sensors, by direct input from the subject via the patient interface unit programming, or a combination thereof.SELECTED DRAWING: Figure 1

Process for a customized production of skin patches, for realizing a customized patch according to a shape of the scalp of a patient for hair thickening purposes, comprising the following main steps: ⋅(a) patient mapping to collect all the information and map the patient to create a digital copy of the same (digital twin) by 3D scanning and production of the template structure by 3D printing; ⋅(b) setting of the template for machining consisting in the application preferably of the compact elastic polyurethane; ⋅(c) application of the hair by approaching the same to the template connected to the suction system: ⋅o suction of the hair inside special holes; o heating the polymeric film close to the melting point, incorporating the hair therein so as to obtain the desired natural hair effect; o cooling.

The present disclosure describes a dermal patch including at least a support layer and a medicament depot including a medicament. The dermal patch is configured to support, protect, and / or medicate a wound during a healing process.

The present invention relates to a bioresorbable skin substitute A) for ulcers and wounds obtained by low temperature treatment of a composition A1) comprising: a cellular component a) comprising fibroblasts; a mixture b) comprising hyaluronic acid, fibrin and / or platelet rich plasma gel; the low-temperature treatment comprises the following steps: cooling at 4 DEG C and holding the composition A1) at this temperature for 1 to 2 hours; the composition A1) is frozen at-20 DEG C and kept at this temperature for at least 18 hours.

A dermal patch device for acquisition and analysis of a physiological sample from a subject can include, a lancet port configured to receive a lancet to pierce the skin of the subject and thereby obtain the physiological sample, a sensor disposed in a sensor chamber, and a plurality of fluid pathways. The dermal patch device can further include a first fluid-filled ampoule, a second fluid-filled ampoule, and a third fluid-filled ampoule. The first fluid-filled ampoule can be actuated to release calibration fluid into the sensor chamber via a first group of the fluid pathways. The second fluid-filled ampoule can be actuated to evacuate the calibration fluid from the sensor chamber via a second group of the fluid pathways among the plurality of fluid pathways. The third fluid-filled ampoule can be actuated to draw the physiological sample into the sensor chamber via a third group of the fluid pathways.

The present disclosure generally relates to liposomes and liposomal compositions, as well as microneedle arrays comprising said liposomes or liposomal compositions, as well as skin patches comprising said microneedle arrays, as well as methods and uses of the same, relating to delivering a proteinaceous antigen to a subject and / or desensitising a subject to an allergen. Said liposomes and liposomal compositions comprise a lipid component comprising or consisting essentially of or consisting of dipalmitoylphosphocholine (DPPC), dipalmitoylphosphatidylglycerol (DPPG), and a sterol.

Packaging pouch for Cosmetic hydrocolloid skin patch (front)

A skin patch that is adherable to human skin over a blemish on the skin has an outer layer that forms a physical barrier over the blemish when applied thereto and a hydrocolloid layer attached to the outer layer that contacts the blemish when applied thereto. A thermochromic material is on the skin patch and / or waterproof packaging encapsulating the skin patch. The thermochromic material indicates the skin patch is at a predetermined temperature.

A skin patch that is adherable to human skin over a blemish on the skin has an outer layer that forms a physical barrier over the blemish when applied thereto and a hydrocolloid layer attached to the outer layer that contacts the blemish when applied thereto. A thermochromic material is on the skin patch and / or waterproof packaging encapsulating the skin patch. The thermochromic material indicates the skin patch is at a predetermined temperature.