15 results about "Biodegradable metal" patented technology

The invention provides a degradable and stretchable wireless sensor with a multilayer circuit and a preparation method of the degradable and stretchable wireless sensor. The wireless sensor comprises an integrated folding structure and a packaging layer, the integrated folding structure comprises a plurality of layers of snakelike wire structures and a plurality of electrode plates; the snakelike wire structure provides inductance, and the electrode plate provides capacitance; the snakelike wire structure is formed by a planar and multi-cycle snakelike wire structure formed by a biodegradable metal and biodegradable polymer composite layer through multiple times of 180-degree twisting and folding, and patterns of the snakelike wire structure are overlapped after folding so as to realize effective series connection of the inductance coils; the electrode plates are bonded with each other through a biodegradable dielectric layer; the snakelike wire structure adopts a neutral axis separation design at the arc section, namely, the wire width is divided into multiple strands. Reliable series connection of multiple layers of coils can be achieved, inductance is effectively increased, high-frequency resistance is reduced, and therefore wireless transmission performance is improved, and meanwhile the requirements for flexibility, stretchability and biodegradability are completely met.

The self-current-generating skin-applied patch includes a first region that contacts the user's skin and a second region that is spaced apart from the first region and contacts the adjacent skin that the first region contacts. The first region or the second region contains a biodegradable metal that contacts the user's skin or reacts with moisture in tissue to be decomposed and absorbed. The first region or the second region is provided as a thin sheet-like structure integral with the first region that directly contacts the user's skin and has at least one penetration that allows fluid delivery from the side opposite to the skin contact; a second electrode layer made of a different material that has a different standard reduction potential from the material that makes up the first electrode layer, located on the side opposite to the skin contact of the first electrode layer while being insulated from the first electrode layer, and at least a portion of the second electrode layer extends to be electrically connected to the second region; and a carrier layer that is a thick sheet-like layer located on the side opposite to the skin contact of the first electrode layer and is made of a hydrophilic material that can carry an ionic solution. The self-generated microcurrent can provide sufficient iontophoresis of active ingredients and other microcurrent effects even without a separate power source such as a battery.

Proposed is a self-current-generating skin-applicable patch with a first area in contact with the skin and a second area adjacent to and spaced apart from it, where either area contains a biodegradable metal, decomposable and absorbable through skin contact or reaction with tissue moisture. The patch includes a first electrode layer directly contacts the skin as a thin sheet integrated with the first area and has at least one fluid-transferable penetration part, a second electrode layer of a material with a different standard reduction potential is positioned opposite a skin-contacting side, partially extending to connect electrically to the second area, and a support layer, a hydrophilic sheet of predetermined thickness, is positioned opposite the skin-contacting side, having an ionic solution supported. Thus, sufficient iontophoresis and other micro-current effects with active ingredients are achieved through self-generated micro-current, even without a battery-like external power source.

A biodegradable stent is disclosed. The stent includes a tubular member formed of a plurality of interwoven filaments. The filaments comprise a magnesium alloy, preferably a WE22 magnesium alloy. The magnesium alloy may consist essentially of 1.9-2.1 wt. % Yttrium, 1.4-1.6 wt. % Neodymium, 0.4-0.6 wt. % Zinc, and the balance Magnesium. The filaments may have an ultimate tensile strength of 60 to 80 KSI and / or an elongation at break in the range of 2% to 20%, preferably 2% to 10%.

A biodegradable stent is disclosed. The stent includes a tubular member formed of a plurality of interwoven filaments. The filaments comprise a magnesium alloy, preferably a WE22 magnesium alloy. The magnesium alloy may consist essentially of 1.9-2.1 wt. % Yttrium, 1.4-1.6 wt. % Neodymium, 0.4-0.6 wt. % Zinc, and the balance Magnesium. The filaments may have an ultimate tensile strength of 60 to 80 KSI and / or an elongation at break in the range of 2% to 20%, preferably 2% to 10%.

Provided herein is a prosthetic heart valve device including a biocompatible and biodegradable metal frame comprising a proximal end, a distal end, and a sidewall therebetween, the sidewall having a plurality of openings therethrough. The device further includes a biocompatible and biodegradable polymeric heart valve having an annular portion attached at least one contact point to the proximal end of the frame and at least one leaflet attached to and extending distally from the annular portion.

A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold.

A biodegradable, biocompatible metal alloy composition suitable for orthopedic implants, consisting of magnesium as the main component (at least 50 wt%) and at least one alloying element selected from calcium, zinc, manganese and strontium, wherein the alloy exhibits a controlled degradation rate and sufficient mechanical strength under physiological conditions to support bone healing.

This application belongs to the field of biomedical materials technology, and more specifically, relates to a piezoelectrically active intelligent biodegradable three-dimensional porous scaffold, its preparation method, and its application. This application involves ultrasonically mixing a suitable ratio of piezoelectric white calcium phosphate stone and a biodegradable metal material, allowing the piezoelectric white calcium phosphate stone to be uniformly adsorbed onto the surface of the biodegradable metal material via physical adsorption. The resulting composite powder is then 3D printed to prepare a three-dimensional porous scaffold with excellent mechanical properties, good biosafety, sensitive piezoelectric response, and adaptively adjustable degradation rate. This scaffold provides good support for critical bone defects and sensitively detects the stress at the critical bone defect site. Through stress, a microcurrent is generated within the three-dimensional porous scaffold, promoting the degradation of the biodegradable metal material and the formation of new bone. The degradation rate is adaptively adjusted according to the stress magnitude to match the bone remodeling rate, effectively promoting bone remodeling.

The invention discloses a degradation behavior simulation method and system for a biodegradable metal intravascular stent. The method comprises the following steps: establishing a free energy functional corresponding to the metal intravascular stent; constructing an evolution equation of a phase field evolution mechanism; constructing an initial structure of the metal intravascular stent, setting a boundary condition and a load environment, calling a finite element solver to perform multi-field coupling simulation calculation based on the free energy functional, the phase field evolution mechanism and the damage mechanical model, and obtaining evolution distribution of variables corresponding to coordinate positions along with time; and analyzing a simulation result, extracting a conclusion index, and outputting the result. According to the method, the spatial heterogeneity of the material performance is considered, the natural expansion path of the corrosion interface is simulated through the thermodynamic driving principle, physical unified modeling between the corrosion process and mechanical attenuation is achieved, high precision and adaptability are achieved, and the structural integrity evolution of the support in the service process can be effectively predicted.

The invention relates to the technical field of biomedical engineering and implantable medical instruments, in particular to a biodegradable flexible wireless implantable intracerebral heating device and a preparation method thereof. The device is of a layered structure and sequentially comprises a porous bioprotein substrate layer and a silk protein nanofiber membrane prepared by adopting an electrostatic spinning process from bottom to top, and the crystallinity and degradation rate of the silk protein nanofiber membrane are adjusted through ethanol annealing treatment. And the lower hydrophobic encapsulation layer is positioned on the substrate layer, is made of a biodegradable hydrophobic polymer, preferably polylactic acid (PLA), and is used for isolating biological fluid. And the wireless heating layer is positioned on the lower hydrophobic packaging layer and is formed by depositing a biodegradable metal material, preferably zinc (Zn). And the upper hydrophobic packaging layer covers the wireless heating layer and forms a sealed package for the heating layer together with the lower layer, so that the metal layer is prevented from being corroded by the body fluid too early. The device aims at solving the problems that an existing intracerebral implantation device needs to be taken out through a secondary operation and mechanical mismatch is caused.

This invention discloses a biodegradable metal closure clip, a hemostasis system, and a method for preparing the closure clip, belonging to the field of medical device technology. The biodegradable metal closure clip is made of biodegradable metal materials such as pure magnesium or magnesium alloy. The clip includes a first clamping arm, a first inclined arm, an arc-shaped transition section, a second inclined arm, and a second clamping arm connected in sequence. Both the first and second clamping arms extend along a first direction and are spaced apart along a second direction. The angle between the first and second inclined arms is α, which is 80°–140°. The diameter of the arc-shaped transition section is 0.4 mm–0.7 mm. The biodegradable metal closure clip provided by this invention not only degrades in vivo but can also be continuously fired within the clamping forceps.

The present invention relates to a core-shell particle (A) formed from a core (B) comprising a thermoplastic polyester (C) having a melting range below 160° C. and a shell (D) comprising partially water-wettable particles (E) made from a metal oxide having a methanol number below 30, the metal content of the core-shell particle (A) being at least 2.5% by weight. The present invention also relates to a method for producing the core-shell particle (A), in which in a first step the thermoplastic polyester (C) is heated above said melting range, whereby it becomes flowable and is emulsified in water with the particles (E) to obtain a particle-stabilized oil-in-water emulsion (G) having a discontinuous phase comprising the molten polyester (C) and a continuous phase comprising water, and in a second step the emulsion (G) is cooled below the melting range of the polyester (C), the molten particle-stabilized polyester droplets (C) solidify and the particles (E) adhere to the surface of the particles of the polyester (C), and the core-shell particle (A) is obtained.

The application belongs to the technical field of metal processing fluid, and discloses a low-carbon biodegradable metal processing fluid, which comprises the following components in percentage by mass: 4-6% of isopropyl alcohol amine, 1-3% of nano silicon corrosion inhibitor, 2-5% of ternary carboxylic acid rust inhibitor, 0.5-2.5% of benzotriazole, 5-10% of 182 self-emulsifying ester, 4-6% of castor oil acid, 40-60% of DOTP, 4-8% of gelberol, 2-4% of ether carboxylic acid complexing agent, 2-5% of cashew phenol polyoxyethylene ether 5EO, 4-8% of cashew phenol polyoxyethylene ether 2EO, 0.4-0.6% of potassium hydroxide, and the balance of water. The low-carbon biodegradable metal processing fluid does not contain harmful substances, has excellent environmental protection performance, has good lubricity, and can be applied to the processing of metals such as copper, aluminum and its alloys, magnesium and its alloys, and has a good application prospect.

The invention relates to the technical field of medical apparatus and instruments, and provides a biodegradable metal intravascular stent and application thereof.The biodegradable metal intravascular stent comprises a plurality of main body structure supporting rings; the main body structure supporting rings are transversely and sequentially connected and then longitudinally surround to form a tubular structure, every two adjacent main body structure supporting rings are connected through a plurality of connecting rods arranged at intervals, and each main body structure supporting ring comprises a plurality of main body units connected to form a wavy structure. The design of the non-concentric arc part in the main body unit not only improves the radial supporting force of the stent, but also enables the residual stress to be distributed more uniformly. The design of the three straight rod parts and the two inflection curve parts can better avoid the interference problem generated in the pressing, holding and expanding process of the stent, the connecting rod is of an s-shaped structure, the phenomena that due to bending, a traditional linear connecting rod is uneven in stress in the circumferential direction, the bent inner side unit makes contact, and the bent outer side warps are obviously improved, and the stability of the stent is improved. The flexibility and the compliance of the stent are greatly improved.