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224results about How to "Improve the degradation problem" patented technology

Compositions and methods for enhancing structural and functional nervous system reorganization and recovery

The present invention provides methods and compositions for enhancing recovery in a subject suffering from damage to the nervous system. In particular, the invention includes a method for promoting recovery and / or reorganization in the nervous system of a subject in need of enhancement of recovery and / or reorganization of the nervous system as a result of ischemic, hemorrhagic, neoplastic, degenerative, or traumatic damage by focally administering a composition comprising a proteolysis-enhancing agent such as tissue plasminogen activator (tPA), plasmin, or a PAI inhibitor to the nervous system of the subject. In some embodiments an additional active agent is also administered. The composition can be delivered using a variety of techniques including injection, via infusion pump, from an implantable microchip, or using a polymeric delivery vehicle. The composition can be administered, for example, to one or more subdivisions or areas of the brain, the spinal cord, or to one or more nerves or nerve tracts innervating diverse regions of the body. The invention also includes a drug delivery device for implantation into the nervous system to promote nervous system reorganization and / or recovery following ischemic, hemorrhagic, neoplastic, traumatic or degenerative damage, the drug delivery device comprising a biocompatible polymer and a proteolysis-enhancing agent such as tissue plasminogen activator (tPA), plasmin, or a PAI inhibitor, wherein the proteolysis-enhancing agent is released from the polymer in an amount effective to promote structural reorganization of the nervous system. In some embodiments the biocompatible polymer is a hydrogel.
Owner:THE BRIGHAM & WOMEN S HOSPITAL INC +1

Preparation method of petroleum degrading bacteria solid inoculant and method for restoring petroleum-polluted soil by using prepared solid inoculant

The invention relates to a preparation method of a petroleum degrading bacteria solid inoculant. The preparation method comprises the following steps: A, screening and domestication of the petroleum degrading bacteria; B, preparation of a seed culture solution; C, fermentation of the solid inoculant; and D, drying, pulverization, measurement and packaging of composted products. The petroleum degrading bacteria solid inoculant has the beneficial effect of improving the petroleum dissolution effect by taking a nonionic surfactantpolysorbate-80 (tween 80) as a solubilizer. The preparation method has the advantages that solid fermentation raw materials are easy to get and the process is relatively simple; and the solid inoculant contains a large amount of carbon and nutrient elements so as to provide more proper matrix for the growth of the bacteria, has strong affinity for the microorganisms, has immobilization efficiency, is capable of improving the competitiveness and degrading efficiency of the added microorganisms and indigenous microorganisms, and is convenient to transport and operate agriculturally and suitable for the large-scale in-situ biological remediation of the petroleum-polluted soil.
Owner:QINGDAO AGRI UNIV

Method of restoring soil polluted by heavy metal

The invention relates to remediation of heavy metal pollution in the environment, in particular to a method of restoring soil polluted by heavy metal, which belongs to the field of environmental pollution remediation. The method is characterized in that a root system of ciliate desert-grass is used for absorbing arsenic from the soil, the arsenic from the soil is stored in leaves to ensure that the content of arsenic in the leaves of the ciliate desert-grass reaches 0.5-0.8 %, the leaves of the ciliate desert-grass are removed periodically, the underground part is reserved, and arsenic transportation and transfer can be performed continuously, so that the purpose of lowering the content of arsenic in the soil is achieved. The method has the benefits that the method is low in cost and high in restoring efficiency, simplifies the soil restoring procedure and is suitable for popularization and application; the harvested leaves are subjected to safe landfill or incineration concentratedly; no secondary pollution is generated; the diversity of soil organisms is restored and improved; a new plant resource variety is developed for a plant for restoring the soil polluted by the heavy metal; and a new advancement and development space is brought to the deep development of a plant restoring technology.
Owner:李银亭

Method for rehabilitating uranium contaminated soil by use of functional plant community

ActiveCN103521510AThe build structure is completeGrow fastContaminated soil reclamationIlex cornutaPlant community
The invention relates to a method for rehabilitating uranium contaminated soil by use of a functional plant community. According to the method, broussonetia papyrifera and Ilex cornuta, and reed, Pteris multifida Poir and difformed galingale herb (herbaceous plants), which can enrich uranium in the soil are selected to construct a stable plant community with a function of in-situ repairing for uranium contaminated soil, wherein all plants in the plant community can enrich uranium in the uranium contaminated soil and can transport the uranium into an overground part of the plants, thereby achieving the purpose of rehabilitating the uranium contaminated soil. The method comprises the following steps of firstly, performing seed treatment and sowing; secondly, trimming and fertilizing; thirdly, harvesting; and fourthly, treating in a concentrating manner. The method does not need other auxiliary means and is capable of overcoming the disadvantages that the plant species structure is simple, the plant community is instable and easy to degrade, the maintenance cost is high, the plant diseases and insect pests are more and the ecological functions are at a low level when the single plant species is used for repairing the uranium contaminated soil in an existing method, the five plants have synergistic effect, and the repairing efficiency is improved remarkably compared with that of the method adopting the single plant species for rehabilitating the uranium contaminated soil.
Owner:NANHUA UNIV
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