85 results about "Isovanillin" patented technology

Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all three in combination. The agents are effective for the treatment of human conditions, especially human cancers.

Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all three in combination. The agents are effective for the treatment of human conditions, especially human cancers.

The invention relates to the field of organic synthesis and discloses a neohesperidin synthesis technology. The neohesperidin synthesis technology comprises the following steps of adding phloroacetophenone-4'-beta-neohesperidin and isovanillin (CAS: 621-59-0) as initial raw materials and a low-carbon alcohol solvent having the content of more than 98wt% into a three-necked flask, carrying out stirring for dissolution, feeding N2 into the three-necked flask to expel air in the three-necked flask, carrying out heating, orderly adding a main catalyst and a cocatalyst into the three-necked flask, carrying out timing at backflow starting time, stopping heating after the reaction lasts for 2-8h, carrying out cooling to a room temperature, carrying out filtration, washing the filter cake by a small amount of hot low-carbon alcohol, and carrying out vacuum drying at a temperature of 50 DEG C to obtain white solid neohesperidin powder. Compared with the existing neohesperidin synthesis technology, the neohesperidin synthesis technology provided by the invention has the advantages of low cost, high yield, high purity and small environmental pollution and is suitable for neohesperidin industrial production.

A process for conveniently and efficiently producing a highly pure cinnamaldehyde derivative, for example, (2E)-(3-hydroxy-4-methoxy)cinnamaldehyde, which comprises reacting a benzaldehyde derivative, such as isovanillin and the like, with acetaldehyde in the presence of an alkali, in particular preferably, dropping acetaldehyde little by little thereto in an aqueous solution at a low temperature for the reaction thereof. The cinnamaldehyde derivative thus obtained is selectively reduced to produce 3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl)propionaldehyde. Further, through a reductive alkylation reaction of the compound thus produced with an aspartame, N-[N-[3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl)propyl]-L-aspartyl]-L-phenylalanine 1-methyl ester, which is useful as a sweetener having a high sweetening potency, can be industrially and efficiently produced. The processes therefor are also provided.

Use of 2-bromo-isovanillin in the preparation of an anticancer medicament and / or radio- and chemotherapy sensitizing medicament is disclosed. The medicament for the treatment of cancers and / or for radio- and chemotherapy sensitization comprising 2-bromo-isovanillin as active ingredient provided herein has the following features: (1) low toxicity, without evident adverse effects; (2) significant therapeutic effect, with remarkable proliferation inhibiting and pro-apoptotic effects in tumor cells; (3) a broad-spectrum anticancer activity; (4) suitable to be used in combination with antimetabolites, to enhance the effects and meanwhile lower the toxicity, and also to reduce multi-drug resistance; (5) convenient and safe administration, the main route being oral.

A process for preparing Erianin (Dihydro Combretastation A-4), wherein 3,4,5-trimethoxy benzaldehyde is converted to phosphonium salt or phosphonate ester or the likes thereof, then reacted with isovanillin (3-hydroxyl-4-methoxyl benzaldehyde) including a protected hydroxyl in the 3-position, followed by hydrogenation and deprotection.