1540 results about "Benzyl group" patented technology

The invention belongs to the field of skin care products, and particularly relates to an anti-wrinkle and anti-aging composition as well as a preparation method and application thereof, and the anti-wrinkle and anti-aging composition comprises neurotransmitter inhibition peptide, signal peptide, madecassoside, inositol and glycosylglycerol. The neurotransmitter inhibition type peptide is at least three of acetyl hexapeptide-8, arginine / lysine polypeptide, dipeptide diaminobutyrylbenzylamide diacetate and acetyl octapeptide-3, and the signal type peptide is at least two of palmitoyl pentapeptide-4, decapeptide-4 and acetyl tetrapeptide-9. Compared with the prior art, all the components of the anti-wrinkle and anti-aging composition act on different anti-aging pathways and can be matched with one another from multiple aspects of oxidation resistance, inflammation resistance, moisturizing, cell viability enhancement, wrinkle reduction and the like, a more comprehensive and better anti-aging effect is provided, skin aging is comprehensively resisted, the skin is in a more young state, and the anti-wrinkle and anti-aging composition has the advantages that the anti-wrinkle and anti-aging effects are achieved. And the anti-wrinkle and anti-aging composition is small in irritation and good in stability.

The invention discloses a high-barrier antibacterial packaging material, a preparation method thereof and a packaging bag, and belongs to the technical field of packaging, the packaging material comprises the following raw materials by weight: 75-85 parts of polylactic acid, 15-25 parts of poly (butylene succinate), 2-6 parts of epoxidized urushiol, and 1-3 parts of benzyl quaternary ammonium salt modified montmorillonite; the epoxidized urushiol is prepared by carrying out epoxidation reaction on urushiol and organic peroxy acid; the packaging material further comprises the following raw materials: 2-5 parts of sepiolite fiber loaded magnesium oxide; according to the invention, biodegradable polylactic acid and poly (butylene succinate) are taken as base materials, and epoxidized urushiol is taken as a reactive compatilizer, so that the compatibility between polylactic acid and poly (butylene succinate) is improved, and meanwhile, the binding property between a polymer matrix and benzyl quaternary ammonium salt modified montmorillonite and sepiolite loaded magnesium oxide is enhanced; the packaging material with good mechanical property, barrier property and antibacterial property is obtained.

The present invention relates to the technical field of coatings and discloses a method for preparing an EVA waterproof coating. Activated montmorillonite reacts with toluene diisocyanate to obtain isocyanate-modified montmorillonite. EVA is hydrolyzed under the catalysis of potassium hydroxide to obtain hydroxylated EVA. An epoxy trisiloxane intermediate reacts with terephthalic acid under ring-opening esterification with benzyltriethylammonium chloride to obtain p-hydroxytrisiloxane benzoate. P-hydroxytrisiloxane benzoate, hydroxylated EVA, and isocyanate-modified montmorillonite are cross-linked with toluene diisocyanate under the catalysis of stannous octoate, and a defoamer and a dispersant are added thereto and stirred uniformly to obtain an EVA waterproof coating. The EVA waterproof coating prepared by the present invention has good mechanical properties and waterproof properties.

The invention provides a composition with an instant and long-acting anti-aging effect and application thereof. The composition comprises a component A, a component B and a component C, the mass ratio of the raw materials is (1-10): (1-4): (0.05-0.2); the component A is prepared from the following components in parts by weight: 0.01 to 0.5 part of acetyl octapeptide-3, 0.01 to 0.5 part of dipeptide diaminobutyryl benzyl amide diacetate, 0.001 to 0.2 part of arginine / lysine polypeptide, 0.3 to 1 part of caprylyl glycol and 96 to 100 parts of water; the component B is prepared from the following components in parts by weight: 0.001 to 0.2 part of soluble collagen, 5 to 30 parts of glycerol, 0.01 to 0.5 part of sodium dihydrogen phosphate, 0.001 to 0.2 part of disodium hydrogen phosphate and 65 to 100 parts of water; and the component C is tripeptide-29. According to the invention, the quadruple wrinkle fading polypeptide is adopted to block wrinkles in a multi-target full-link manner, so that the product has a very good effect of fading various wrinkles in real time.

The application belongs to the technical field of oil and gas field development, and provides a phase permeability improver, a fracturing fluid system containing the same, and respective preparation methods and applications. The phase permeability improver is obtained by copolymerization and hydrolysis of acrylamide AM, a functional monomer 2-acrylamido-2-methylpropanesulfonic acid AMPS, and cationic hydrophobic monomers A and B; the cationic hydrophobic monomer A is at least one of tetradecyl dimethyl allyl ammonium chloride, hexadecyl dimethyl allyl ammonium chloride, and octadecyl dimethyl allyl ammonium chloride; the cationic hydrophobic monomer B is at least one of methacryloyloxyethyl trimethyl ammonium chloride, acryloyloxyethyl trimethyl ammonium chloride, and acryloyloxyethyldimethyl benzyl ammonium chloride; the phase permeability improver and the fracturing fluid system containing the same can significantly reduce the water phase permeability after fracturing operation, while having a smaller influence on the oil phase permeability, and have a significant effect of stabilizing oil and controlling water, and can significantly improve the stable production effect of fracturing operation in a low-permeability oil reservoir.

Disclosed is a pharmaceutical composition for the treatment of tumors, the pharmaceutical composition comprising (6S, 9aS)-N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl) azetidin-1-yl] pyridin-2-yl} methyl)-6-(2-fluoro-4-hydroxybenzyl)-4, 7-dioxo-2-(propyl-2-en-1-yl) hexahydro-2H-pyrazino [2, 1-c] [1, 2, 3] triazolo [1, 2, 4] triazolo [1, 2, 4] triazolo [1, 2, 4] triazolo [1, 2, 4] triazolo [1, 2, 4] triazolo [1, 2, 4] triazolo [1, 2, 4] triazolo [1, 2, 4] triazolo [ The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof and administered in combination with a MEK inhibitor.

The invention discloses a preparation method of battery-grade lithium trifluoromethanesulfinate, which comprises the following steps: reacting sodium trifluoromethanesulfinate with benzyl halide in a solvent to prepare benzyl trifluoromethyl sulfone, and carrying out hydrogenation reduction on the benzyl trifluoromethyl sulfone under the catalysis of a catalyst to prepare trifluoromethanesulfinic acid, according to the method, all the adopted raw materials are industrial chemicals and are low in price and easy to obtain, the reaction process is mild and controllable, the product purity is high, the battery use requirement is met, and the method has the industrialization prospect.

The invention relates to a method for preparing a nerofloxacin chiral piperidylamine intermediate, which comprises the following steps of: carrying out condensation reaction on 5-hydroxy nicotinic acid which is simple and easy to obtain and is used as a raw material and different alcohols, screening through a series of asymmetric catalytic hydrogenation conditions to obtain optimal reaction conditions, and under the conditions, carrying out reaction on various 3, 3 '-dihydroxy nicotinic acid and 3, 3'-dihydroxy nicotinic acid to obtain the nerofloxacin chiral piperidylamine intermediate. The 2, 5-disubstituted pyridine quaternary ammonium salt is reduced into a tetrahydropyridine product, and the C5 site enantioselectivity of the product is excellent. The preparation method comprises the following steps: selecting methyl (R)-1-benzyl-5-hydroxy-1, 4, 5, 6-tetrahydropyridine-3-carboxylic acid methyl ester as a substrate, completely hydrogenating by using platinum dioxide hydrogen, and then carrying out methyl ester reduction, dehydroxylation, Mitsunobu reaction and protecting group removal to obtain a key chiral intermediate for industrial synthesis of a quinolone antibacterial drug nemonofloxacin with high enantioselectivity and high yield.

The preparation and properties of crystalline polymorphs and solvates of 1-benzyl-8-methyl-1,4,8-triazaspiro-[4.5]-decan-2-one free base and of the mono- and dihydrochloride salts and solvates thereof are disclosed, as is an amorphous polymorph of the dihydrochloride. A pharmaceutical composition containing one or more polymorphs and a method of using that composition are also disclosed.

The invention relates to an anti-wrinkle and anti-aging composition and application thereof. The anti-wrinkle and anti-aging composition is prepared from hydrolyzed rice protein, a bifidus yeast fermentation product lysate, dipeptide diaminobutyryl benzyl amide diacetate, adenosine, hydroxydecyl ubiquinone, ceramide NP, palmitoyl tripeptide-5, carnosine and acetyl hexapeptide-8. According to the present invention, the components achieve the synergistic effect, such that the fibroblast proliferation can be promoted, the cell metabolism can be improved, the generation of collagen, elastin and the like can be promoted, the excellent oxidation resistance can be provided, and the effects of expression line inhibition, existing wrinkle fading and long-term aging resistance can be combined.

The invention belongs to the technical field of drug development, and particularly relates to application of (E)-N-benzyl-2-((5-(thiophenyl) furan-2-yl) methylene) hydrazine-1-thioformamide in preparation of drugs for treating nervous system diseases. The invention aims to provide a medicine which has small toxic and side effects and can target SLC11A2 to treat or improve nerve cell injury. According to the technical scheme, the invention relates to application of (E)-N-benzyl-2-((5-(thiophenyl) furan-2-yl) methylene) hydrazine-1-thioformamide in preparation of a medicine for treating nervous system diseases, in particular to application of (E)-N-benzyl-2-((5-(thiophenyl) furan-2-yl) methylene) hydrazine-1-thioformamide. It is proved that the compound (E)-N-benzyl-2-((5-(thiophenyl) furan-2-yl) methylene) hydrazine-1-thioformamide is small in toxic and side effect, and nerve cell damage can be protected or improved by targeting SLC11A2; and a new choice is provided for treating or improving nerve cell injury.

This invention belongs to the field of veterinary drug technology, specifically relating to a 2,3-disubstituted naphthoquinone compound, its uses, and a preparation method. The 2,3-disubstituted naphthoquinone compound has the general formula: where X is selected from C, NH, O, and S; where X is selected from C, the X-R1 substituent represents an aryl substituent; when X is selected from NH, R1 is selected from hydrogen atom, C1-6 alkyl, C3-6 cycloalkyl, substituted aryl, substituted benzyl, or substituted acyl; when X is selected from O, R1 is selected from hydrogen atom, C1-6 alkyl, C3-6 cycloalkyl, C4-6 cycloalkyl, C5-6 cycloalkyl, C6-6 cyclo ... 3-6 cycloalkyl, substituted benzyl, substituted acyl; when X is selected from S, R1 is selected from C1-6 alkyl, substituted aryl, substituted benzyl; R2 is selected from C1-16 alkyl, substituted aryl, Ra-(CH2)n-, Ra-CO-(CH2)n-; This series of compounds has novel structures, excellent antiparasitic activity, and has been successfully applied in the field of veterinary drugs, solving long-standing safety and toxicity problems; its synthesis process is simple, the conditions are mild, and it can efficiently prepare a variety of 2,3-disubstituted naphthoquinone compounds.

The invention provides an application of N '1, N' 3, N '5-tri ((E)-4-(diphenylamino) benzylidene) benzene-1, 3, 5-tricarbohydrazide (TBTCH) as a piezo-chromic material. The invention provides a novel application of the compound TBTCH, and research shows that the compound has a polycrystalline state property and a piezochromic property, and has two single crystal structures TBTCH-c and TBTCH-g which emit cyan and green fluorescence under different wavelengths; under the action of pressure, the TBTCH-g is converted into an amorphous state from an original crystalline state and is converted into a yellow state sample, and the TBTCH-g can recover to the original state after being fumigated, so that the TBTCH-g has reversible piezochromism performance; and the TBTCH-c changes color under the action of pressure and cannot recover to the original state through a conventional fumigation method, but the TBTCH-g and the TBTCH-c can realize conversion between the TBTCH-g and the TBTCH-c through recrystallization. Therefore, the compound TBTCH can be used as a photochromic material to be applied to the fields of information encryption, intelligent display, biosensing, environmental monitoring and the like.

Provided are a resin composition, a cured product, a prepreg, a metal foil-clad laminate, a resin composite sheet, a printed wiring board, and a semiconductor device. This resin composition comprises an elastomer (A), a thermosetting compound (B), a radical polymerization initiator (C), and a filling material (D), wherein: the elastomer (A) includes a polymer block (a1) containing a radically reactive group-containing styrene compound unit and a conjugated diene compound unit; the thermosetting compound (B) contains a resin (E) having at least two vinylbenzyl groups at the terminal thereof; the content of the filling material (D) is 1-300 parts by mass with respect to 100 parts by mass of the solid content of the resin; and the mass ratio ((A) / (E)) of the elastomer (A) to the resin (E) having at least two vinylbenzyl groups at the terminal thereof is 0.01-1.1.

The present invention relates to a process for the preparation of (6R)-6-(2-(N-(4-(2- (ethylamino)ethyl)benzyl)-N-ethylamino)-4-methoxyphenyl)-5,6,7,8-tetrahydro nap- hthalen-2-ol dihydrochloride (1) and its novel intermediates thereof. Elacestrant dihydrochloride (1) The present invention further relates to a process for the preparation of intermediates of formula (3), formula (4), formula (4a), formula (5), formula (5a), formula (6), formula (6a), formula (7), formula (7a), formula (9) and formula (10). with enantiomeric excess greater than 50%.

The invention discloses a preparation method of a coal slime water treatment flocculant, and relates to the technical field of wastewater treatment.The preparation method comprises the following steps that modified polyacrylamide, modified chitosan, polymeric chloride and water are mixed and stirred by weight, and the coal slime water treatment flocculant is obtained; the modified polyacrylamide is obtained by physically blending a nano cellulose based TiO2 nano composite material and polyacrylamide; the modified chitosan is obtained by grafting N-benzyl-2-(methylacryloyloxy)-N, N-dimethylethane-1-ammonium chloride after SiO2 and chitosan are hybridized through a silane coupling agent, and the modified chitosan is obtained by grafting N-benzyl-2-(methylacryloyloxy)-N, N-dimethylethane-1-ammonium chloride; through the synergistic interaction of the inorganic coagulant, the natural modified polymer and the nano composite material, multiple targets of efficient flocculation, broad-spectrum purification, environment friendliness and cost optimization in slime water treatment are achieved, and the composite material is particularly suitable for high-turbidity and high-organic-matter-load complex slime water quality or heavy metal-containing complex slime water quality and has remarkable industrial application potential.

A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.

The invention discloses a polyamide material with an electromagnetic shielding function, and relates to the technical field of polymer composite materials. The invention discloses a polyamide material with an electromagnetic shielding function. The conductive composite material is prepared from the following raw materials in parts by weight: 40 to 60 parts of modified polyamide resin, 20 to 35 parts of modified conductive filler, 5 to 10 parts of maleic anhydride grafted polyamide, 0.5 to 2 parts of antioxidant, 1 to 3 parts of stearic acid, 3 to 8 parts of ethylene-vinyl acetate, 5 to 10 parts of triphenyl phosphate, 10 to 20 parts of aluminum nitride, 0.5 to 1 part of dodecyl dimethyl benzyl ammonium chloride and 1 to 3 parts of silane coupling agent KH-550 hydrolysate. And 30-60 parts of a 20% silane coupling agent KH-560 ethanol solution. The polyamide material has efficient electromagnetic shielding performance and excellent mechanical strength, high shielding effectiveness under low filler content is achieved through modification design, the melt index adapts to a low-pressure injection molding process, the damp-heat aging performance is stable, the problems of contradiction between shielding and processability, mechanical deterioration and the like of a traditional material are solved, and the polyamide material is suitable for electronic module packaging.

Provided in the present invention are a monosubstituted cyclic ligand, and a preparation method therefor and a use thereof, and a monosubstituted cyclic rare earth complex, and a preparation method therefor and a use thereof, relating to the technical field of contrast agents. The monosubstituted cyclic ligand uses the ring structure of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid as a parent ring, and an R-modified tyrosine group increases the structural rigidity of the parent ring and improves the stability of the complex. Direct introduction of benzyloxy-, ethoxy- or hydroxy-substituted benzyl substituents on the carbon atoms of the DOTA ring maintains the original eight-coordination structure, and improves the relaxation rate of the complex, in addition to increasing the stability of the complex. Compared with Gd-DOTA, both the kinetic inertia and the relaxation rate are improved. The complex formed by the ligand and Gd(III) or Eu(III) is highly stable, and has strong specificity for the liver or for inflammation, and causes no obvious damage to the heart, the liver, the spleen, the lungs or the kidneys.

The invention discloses preparation and application of an amido-functionalized polyionic liquid catalyst, vinyl imidazole hydrobromide and N-(4-vinyl) benzyl diethylamine are used as monomers, N, N '-methylene bisacrylamide is used as a cross-linking agent, and the amido-functionalized polyionic liquid catalyst is prepared through a free radical copolymerization method. The imidazole / amido functionalized cross-linked PILs with multiple active sites are prepared by one-step synthesis through a hydrothermal polymerization method. The catalyst has catalytic active sites of amido, imidazolyl and Br, so that the catalyst can efficiently catalyze the cycloaddition reaction of CO2 and epoxide at 80 DEG C and normal pressure in the absence of a solvent and a co-catalyst.

The invention provides a fracturing fluid base fluid, a water-based fracturing fluid and a preparation method of the water-based fracturing fluid, and relates to the technical field of oil fields. The fracturing fluid base fluid is prepared from the following components in percentage by mass: 97.3 percent to 98.1 percent of produced water, 0.5 percent to 0.55 percent of hydroxypropyl guar gum, 0.004 percent to 0.005 percent of sodium hypochlorite, 0.015 percent to 0.03 percent of citric acid, 0.1 percent to 0.18 percent of dodecyl dimethyl benzyl ammonium bromide, 0.2 percent to 0.3 percent of ethylenediamine tetraacetic acid disodium salt, 0.3 percent to 0.5 percent of a temperature stabilizer, 0.6 percent to 0.8 percent of a pH value regulator and 0.2 percent to 0.3 percent of a cleanup additive; the pH value of the fracturing fluid base fluid is 7.5. The fracturing fluid base fluid prepared from the produced water has the advantages of rapid adhesion, no precipitation, no weak crosslinking and no floccule phenomenon, so that the guar gum fracturing fluid prepared from the fracturing fluid base fluid has the characteristics of self-adaption to a reservoir, ultralow damage and high performance.

The invention provides a method for reversibly regulating and controlling the water solubility of long-chain alkyl trimethyl ammonium bromide, which comprises the following steps of: mixing sodium benzyl selenopropionate serving as an auxiliary agent with long-chain alkyl trimethyl ammonium bromide, adding water for dissolving, reducing the Krafft temperature of the long-chain alkyl trimethyl ammonium bromide to 10 DEG C or below, and then adding sodium benzyl selenopropionate, according to the method, benzyl selenium sodium propionate is oxidized into benzyl selenium oxygen sodium propionate by adding an oxidizing agent, so that the KT of long-chain alkyl trimethyl ammonium bromide is increased, and the water solubility of the long-chain alkyl trimethyl ammonium bromide is reduced, so that the long-chain alkyl trimethyl ammonium bromide is crystallized and separated out from an aqueous solution, and the separation, recovery and reutilization of the long-chain alkyl trimethyl ammonium bromide are realized; the residual water phase solution after the long-chain alkyl trimethyl ammonium bromide is recovered can be used as the plant leaf selenium fertilizer.

The invention discloses a preparation method of semeglutide, which comprises the following steps: respectively using 8-bit and 12-bit single pseudo-proline serine in a combined manner, using 1-2-bit, 3-4-bit, 5-6-bit and 29-30-bit dipeptide fragments in a combined manner, using 27-29-bit and 14-16-bit 2, 4-dimethoxy benzyl modified glycine tripeptide fragments in a combined manner, and further comprising a 20-bit lysine fragment with a side chain group, the method is used for synthesizing semeglutide resin, and the semeglutide resin is cracked and purified to obtain the semeglutide. The preparation method combining the fragments is beneficial to completing solid phase coupling of the semeglutide, greatly improves the substitution value of the semeglutide peptide resin and the purity and yield of a crude product, remarkably reduces the purification difficulty of the crude product, finally reduces the synthesis cost, and is beneficial to industrial mass production.

The invention belongs to the technical field of chemical materials, and particularly relates to a high-stability weather-resistant chip packaging adhesive used in an air and space extreme environment and a preparation method of the high-stability weather-resistant chip packaging adhesive. The invention relates to a flame-retardant coating which comprises the following components: bisphenol A type epoxy resin, alicyclic epoxy resin, organic silicon modified epoxy resin, hydroxyl-terminated polyether polyol, core-shell rubber, micron boron nitride, aluminum oxide, nano silicon carbide, graphene (GNP), dicyandiamide (DICY), 2-ethyl-4-methylimidazole (EMI-24), a hindered amine light stabilizer, nano dicerium trioxide and benzyl glycidyl ether. By adopting an organic silicon modified epoxy resin and multi-particle-size grading filler composite system and a stepped curing process, the problems of easy brittle fracture, insufficient heat conductivity, poor radiation resistance, interface layering caused by non-uniform filler dispersion and the like of a traditional epoxy resin-based packaging adhesive in a wide temperature range are solved.

The invention relates to the technical field of petroleum drilling fluid loss reduction, and discloses an anti-divalent salt fluid loss agent for drilling fluid, which is prepared by the following steps: step 1, beta-cyclohexylamine and 6-chloro-1-hexene are subjected to a reaction to obtain alkenyl beta-cyclohexylamine; step 2, initiating polymerization of alkenyl beta-cyclopentadiene, a hyperbranched monomer pentaerythritol triallyl ether and 2-acrylamide-2-methylpropanesulfonic acid under the action of azobis (isobutylamidine hydrochloride), so as to obtain an intermediate A; 3, 3-dimethylamino-1-propylamine and palmitic acid are subjected to a reaction, and an intermediate 2 is obtained; 4, the intermediate 2 and benzyl chloride are subjected to a reaction, and quaternary ammonium salt modified fatty acid is obtained; and 5, stirring and mixing the intermediate A, quaternary ammonium salt modified fatty acid and coupling agent modified walnut powder to obtain the divalent salt resistant filtrate reducer for the drilling fluid. The anti-divalent salt filtrate reducer for the drilling fluid has a relatively good anti-divalent salt effect.

The invention discloses thermochromic dye as well as preparation and application thereof, and belongs to the technical field of fine chemical engineering. The preparation method comprises the following steps: firstly, taking a fluorane dye as a raw material, and introducing an amino group into a fluorane dye structure by utilizing a reaction between lactone and alkyl diamine; and then preparing the thermochromic dye by utilizing the aldehyde amine reaction between the amino fluorane dye and the benzyloxy hydroxy benzaldehyde. The parent structure of the prepared thermochromic dye fluorane is connected with an alkyl chain and a benzylbenzaldehyde structure through a stable covalent bond, and latent heat of phase change comes from Van der Waals force between methylene on the alkyl chain and conformation overturning energy of the alkyl chain in the structure. And two benzene rings in the benzyloxy hydroxy benzaldehyde structure are used for hindering temperature crystallization below the melting point, so that the material melting and crystallization processes are regulated and controlled.

The invention relates to the field of solid-state batteries, in particular to an electrolyte and a preparation method of an electrolytic copper foil for a solid-state battery. The electrolyte comprises the following components by concentration: 80 to 100 g / L of Cu < 2 + >, 105 to 120 g / L of sulfuric acid, 5 to 25 g / L of gelatin, 10 to 40 g / L of isothiourea propanesulfonic acid inner salt, 3 to 15 g / L of diethyl propyne amine, 5 to 35 g / L of (R)-4-benzyl thiazoline-2-thioketone, 10 to 30 mg / L of Cl <->, and the balance of water. By adopting a specific formula and process, the tensile strength of the prepared copper foil reaches 400-500MPa, the elongation is greater than or equal to 5.0%, the roughness Ra is greater than or equal to 0.45 mu m, the roughness Rz is greater than or equal to 2.50 mu m, and the specific surface area is greater than 0.36 m < 2 > / g; the problems that in the prior art, a copper foil is prone to deformation and breakage and high in interface impedance are solved, and therefore the charge-discharge efficiency and the cycle performance of the solid-state battery are improved.

Oil dispersion compositions comprising sulfonylurea-florpyrauxifen-benzyl mixtures, having improved stability, are disclosed.

The invention provides a synthesis method of a thioether ligand and a palladium-catalyzed 2-aryl indole compound, and designs an application of the biphenyl thioether ligand and a palladium catalyst in preparation of the 2-aryl indole compound. Indole and arylboronic acid are subjected to a reaction under the action of a palladium catalyst and a biphenyl sulfide ligand, and the structural formula of the biphenyl sulfide ligand is shown in the specification. Ar is phenyl, furyl, thienyl, naphthyl or phenyl substituted by one or more substituent groups; r1 is methyl, methoxyl, fluorine atom, chlorine atom, bromine atom or methyl ester group; r2 is the same or different and is methyl, ethyl, isopropyl, isobutyl, cyclohexyl, benzyl, n-butyl or n-hexyl; r3 is alkoxy, alkylthio, substituted amino or halogen; the palladium catalyst is a divalent palladium compound.

The present application provides a photosensitive resin composition, dry film resist, photosensitive dry film and application thereof. The photosensitive resin composition comprises 45-60 parts of alkali-soluble resin, 35-50 parts of photopolymerization monomer, 2.5-5 parts of photoinitiator and 0.1-0.8 parts of sensitizer; the sensitizer is a compound shown in the general formula, R1 represents methylene or carbonyl, n represents 0 or 1; R2 represents phenyl, and any hydrogen atom on R2 is optionally substituted by methoxy, C1-C 10 alkyl, phenyl, benzyl or phenoxy. The sensitizer of the present application can make the product have better photosensitivity and resolution. Moreover, based on the above specific weight parts of alkali-soluble resin, photopolymerization monomer, photoinitiator and sensitizer, the comprehensive performance of the product of the present application is better.