Beneficial Effects of Increasing Local Blood Flow,Beneficial effects of increasing local blood flow,Transdermal delivery of beneficial substances effected by a hostile biophysical environment,Transdermal Delivery of Beneficial Substances Effected By a Hostile Biophysical Environment,Technique for producing Jinhuaqianliang tea (flower coil tea)

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364 results about "Theophylline" patented technology

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Theophylline is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema). It must be used regularly to prevent wheezing and shortness of breath.

Beneficial Effects of Increasing Local Blood Flow

InactiveUS20090105336A1Increase oxygenationImprove tissue nutritionBiocideOrganic active ingredientsTopical creamArginine

The present invention provides a treatment for enhancing the ability of the body to heal wounds. A topical cream is described which improves blood flow by the transdermal delivery of the nitric oxide precursor L-Arginine either alone or with an adjunct, theophylline. The delivery of the active agents is accomplished by use of a vehicle which contains a hostile biophysical environment which is also hostile to hydrogen bond formation.

Owner:STRATEGIC SCI & TECH

Beneficial effects of increasing local blood flow

InactiveUS20110028548A1Increase oxygenationImprove tissue nutritionBiocidePeptide/protein ingredientsArginineNitric oxide

The present invention generally relates to the improvement of tissue health by increasing local blood flow. In some aspects of the invention, increased local blood flow is effected by the transdermal delivery of the nitric oxide precursor L-arginine and/or its derivatives alone, or optionally in conjunction with an adjunct such as theophylline. The transdermal delivery is effected, in certain embodiments through the means of a hostile biophysical environment, such as that created by a high ionic strength environment. Various pathological states caused by, or occurring in conjunction with, insufficient blood flow, can be treated using the systems and methods of the invention as described herein. In other embodiments, increased blood flow using the systems and methods of the invention may result in enhanced healing, for example, through greater availability of the constituents of the blood. Examples of conditions which may benefit from increased blood flow include, but are not limited to, erectile dysfunction, hair loss, female sexual dissatisfaction, sagging facial or other body tissue, peripheral vascular disease including claudication, neuropathy, skin ulcers, bone healing, wound healing, viral and bacterial infection, and skin grafting.

Owner:STRATEGIC SCI & TECH

Transdermal delivery of beneficial substances effected by a hostile biophysical environment

InactiveUS20090221536A1Good for healthImprove physical functionBiocideNervous disorderSexual functionArginine

The present invention generally relates to the transdermal delivery of substances and, in some embodiments, to the transdermal delivery of beneficial substances by a hostile biophysical environment. In one aspect, various methods for the transdermal delivery of beneficial substances are disclosed. By creating a hostile biophysical environment, beneficial substances may be delivered, according to certain embodiments, through the stratum corneum of the skin into the body. Beneficial substances include, but are not limited to, pharmaceutical agents, drugs, vitamins, co-factors, peptides, dietary supplements, and others. The beneficial effects disclosed include, for instance, relief of pain and inflammation, prevention and healing of ulcers of the skin, relief of headache, improved sexual function and enjoyment, growth of hair on the scalp, improving muscle size and / or function, removing body fat and / or cellulite, treating cancer, treating viral infections and others. A hostile biophysical environment may also be used in conjunction with systems and methods for increasing local blood flow, according to one set of embodiments. For example, by using a nitric oxide donor such as L-arginine, local blood flow may be increased, e.g., by transdermally delivering the nitric oxide precursor. The nitric oxide donor may be the sole cause of increased blood flow, or it may be supplemented with an adjunct such as theophylline.

Owner:STRATEGIC SCI & TECH

Transdermal Delivery of Beneficial Substances Effected By a Hostile Biophysical Environment

ActiveUS20080280984A1Improved graftGood lookingBiocideNervous disorderSexual functionDietary supplement

Owner:STRATEGIC SCI & TECH

Technique for producing Jinhuaqianliang tea (flower coil tea)

ActiveCN101352191AQuality improvementUniform qualityPre-extraction tea treatmentCooking & bakingThirst

The technology for producing golden flower Qianliang tea (Hua-juan tea) is characterized in that the technology comprises the process steps as follow: plucking criteria-water removing in high temperature-rolling and shaping-pile-fermentation-dry and adding incense-stems picking and sieving-matching and pile-classificaition and weighting-steam softening-moisture detection-adpressing and sizing-premilary test and baking-cultivating golden flower-aerationagitation. The technology is an improved deep processing technology. The processes of the pile-fermentation and the cultivating golden flower ensure that the appearance of the products is ooiu colour, the interior is brown, and even distributed beneficial organism (namely, golden flower)-eurotium cristatum is clearly saw, the shangse is bright red, the taste is pure and aromatic, and the flower is aromatic, and has the health care functions of promoting sleeping, invigorating stomach and promoting digestion, relaxing bowel, slaking thirst and helping produce saliva, antidiabetics, lowering blood pressure, curing bloated, cuing laxness, etc. The technology fully actives microelements such as vitamins contained in tea, mineral composition, 18 amino acid, protein, glucide, folic acid, catchol which are beneficial to human health and easily absorbed, and the cultivation of golden flower has substantial transformation on tea polyphenols, caffeine, and theophylline that are transferred into elements that are beneficial to human health, all ages, expand market, have high cultural value, provide collection opportunity for black tea lovers.

Owner:湖南省安化县晋丰厚茶行有限公司

Transdermal delivery of beneficial substances effected by a hostile biophysical environment

InactiveUS20090123528A1Good for healthImprove physical functionBiocideNervous disorderSexual functionArginine

Owner:STRATEGIC SCI & TECH

Allosteric trans-splicing group i ribozyme whose activity of target-specific RNA replacement is controlled by theophylline

InactiveUS20110003883A1Sugar derivativesMicrobiological testing/measurementCancer cellReverse transcriptase

Provided is an allosteric trans-splicing group I ribozyme whose target-specific RNA replacement activity is controlled by theophylline, wherein the hTERT-targeting trans-splicing ribozyme recognizes mRNA of human telomerase reverse transcriptase (hTERT) as a cancer-specific RNA transcript to bind a theophylline aptamer to an hTERT target trans-splicing ribozyme via a communication module, the hTERT target trans-splicing ribozyme having a verified trans-splicing ability. The allosteric trans-splicing group I ribozyme may be useful to selectively diagnose only cancer cells that express target hTERT RNA, or induce their apoptosis since the activity of the allosteric trans-splicing group I ribozyme is dependently controlled by theophylline to correct target hTERT RNA by the trans-splicing reaction.

Allosteric trans-splicing group i ribozyme whose activity of target-specific RNA replacement is controlled by theophylline

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Owner:IND ACADEMIC COOP FOUND DANKOOK UNIV

Phenylpyridyl compounds for inhibiting phosphodiesterase IV and methods of using same

InactiveUS6153630ASuperior PDE IV inhibitory effectGood choiceBiocideAntipyreticCombinatorial chemistryTheophylline

PCT No. PCT / US96 / 00519 Sec. 371 Date Nov. 13, 1997 Sec. 102(e) Date Nov. 13, 1997 PCT Filed Jan. 11, 1996 PCT Pub. No. WO96 / 21435 PCT Pub. Date Jul. 18, 1996Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram as well as with improved selectivity with regard to PDE III inhibition. In certain aspects of the invention, the compounds also demonstrate PDE V inhibition. Pharmaceutical compositions containing the same and methods of treatment are also disclosed.

Owner:EURO-CELTIQUE SA

Beneficial effects of increasing local blood flow

ActiveUS20130289059A1Increase oxygenationImprove tissue nutritionBiocidePeptide/protein ingredientsArginineInjury mouth

The present invention generally relates to the improvement of tissue health by increasing local blood flow. In some aspects of the invention, increased local blood flow is effected by the transdermal delivery of the nitric oxide precursor L-arginine and / or its derivatives alone, or optionally in conjunction with an adjunct such as theophylline. The transdermal delivery is effected, in certain embodiments through the means of a hostile biophysical environment, such as that created by a high ionic strength environment. Various pathological states caused by, or occurring in conjunction with, insufficient blood flow, can be treated using the systems and methods of the invention as described herein. In other embodiments, increased blood flow using the systems and methods of the invention may result in enhanced healing, for example, through greater availability of the constituents of the blood. Examples of conditions which may benefit from increased blood flow include, but are not limited to, erectile dysfunction, hair loss, female sexual dissatisfaction, sagging facial or other body tissue, peripheral vascular disease including claudication, neuropathy, skin ulcers, bone healing, wound healing, viral and bacterial infection, and skin grafting.

Owner:STRATEGIC SCI & TECH

Benzoxazoles

InactiveUS6372770B1Superior PDE IV inhibitory effectGood choiceBiocideNervous disorderBenzoxazoleTheophylline

Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram, with improved selectivity with regard to, e.g., PDE III inhibition.

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Owner:EURO-CELTIQUE SA

Reagent for stabilization of blood sample cells

ActiveCN104381245AAvoid gatheringDoes not affect molecular analysisPreparing sample for investigationDead animal preservationDipyridamoleAdenosine

The invention discloses a reagent for stabilization of blood sample cells. The reagent comprises 100 micromoles per liter of L beta-cyclodextrin, 100 micromoles per liter of disodium cromoglycate, 0.05% of potassium dichromate, 50 micromoles per liter of triflusal, 100 micromoles per liter of Terutroban, 11 millimoles per liter of sodium citrate, 1.5 millimoles per liter of theophylline, 20 micromoles per liter of dipyridamole, 0.37 millimoles per liter of adenosine, 20 millimoles per liter of glucose and 1.25 millimoles per liter of LPEG. The reagent can stabilize blood cells for at least 36h and prevent blood cell aggregation. Through the reagent, a blood sample subjected to treatment does not influence follow-up sample molecule analysis. The reagent can be widely used for blood sample molecule analysis and detection and is especially suitable for cell or molecular detection such as a microfluidic technology with strict sample cell requirements and an analysis technology platforms such as a flow cytometer with strict sample cell requirements.

Owner:广东国盛医学科技有限公司 +1

Treatment or prevention of acute renal failure

InactiveUS6998404B2Increase urine outputLow creatinine levelBiocideAnimal repellantsVentricular tachycardiaCardiac monitoring

Adenosine receptor antagonists, especially aminophyllline, are used to treat or prevent acute renal failure. In the preferred embodiment, aminophylline is administered by infusion so that it does not exceed a serum theophylline level of 15-20 micrograms / ml, most preferably the aminophylline is administered to achieve a serum theophylline concentration of 3-10 micrograms / ml, with an infusion rate of 0.1-0.6 mg / kg IBW / hour (IBW=ideal body weight). The adenosine receptor antagonist can also be used to help sustain a kidney for transplant purposes. Preferably, aminophylline is loaded while the kidney is still part of the donor. A dose of aminophylline of 5 mg / kg lean body weight is infused into the donor over a 30-60 min period, with cardiac monitoring. The infusion dose is decreased in the event of supraventricular or ventricular tachycardias. The kidney is removed and placed in the standard “cold” bath, but containing aminophylline at a dose of 5-10 micrograms / ml (5-10 mg / l). The kidney is then transported to the recipient. The recipient is similarly preloaded with 5 mg / kg lean body mass aminophylline intravenously over 30-60 min with cardiac monitoring, with a constant infusion of 0.1-0.3 mg / kg lean body mass / hr continuing during the next 24 hours after the kidney is transplanted into the recipient.

Owner:GENOMED

Processing method and application for yeast black tea

InactiveCN101755940AReduce caffeineReduce theophyllineAntibacterial agentsCosmetic preparationsFood additiveBlack tea

The invention provides a processing method and an application for yeast black tea. The method comprises the following steps: Saccharomyces Candidasp. and water are prepared into dampening solution according to the mass proportion of 1:200 to 700, the dampening solution is sprayed on tea leaves so as to lead the Saccharomyces Candidasp. to be uniformly distributed on the tea leaves, and the water content is 18 to 26% after the tea leaves are dampened; the tea leaves are put into a stainless steel fermentation tank for compressing fermentation, the fermentation temperature is within 22 to 45 DEG C, the relative humidity of air is within 80 to 90%, and the fermentation time is within 5 to 10 days; and then the yeast black tea is obtained after fermentation. Compared with the present green tea, black tea, oolong tea, yellow tea, white tea and post-fermented tea, the invention utilizes the fermentation capability of the microorganism Saccharomyces Candidasp. to greatly reduce the contents of caffeine, theophylline and esterified catechin in the tea leaves, thereby leading the yeast black tea not to stimulate a gastrointestinal system and affect the sleeping; moreover, the yeast black tea is sweet and nearly not bitter, so as to be suitable for the requirements of most people for the taste. With obvious antioxidant activity and antibacterial function, the yeast black tea not only can be used as raw materials for special cosmetics and natural medicine, but also can be used for a food additive in the food processing industry.

Owner:冯磊

Method of measuring platelet activation

InactiveUS7011938B2Reduce platelet activationInhibition of activationBiocideSamplingDipyridamoleAdenosine

Platelet activation is measured by determining Mean Platelet Component (MPC) of suspended blood platelets, using a specific anticoagulant composition. The composition comprises at least one component for effecting platelet sphering (for example EDTA), and at least one platelet antagonist (for example at least one of, and preferably all three of theophylline, adenosine and dipyridamole).

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Owner:BARTS & THE LONDON NHS TRUST

Medical antibacterial hydrogel dressing and preparation method thereof

InactiveCN106237374AImprove antibacterial propertiesShort hemostatic timeSurgical adhesivesBandagesArginineArginine ethylester

The invention discloses a medical antibacterial hydrogel dressing and a preparation method thereof. The hydrogel dressing is prepared from the following raw materials: thiolated chitosan, sodium glycerophosphate hydrate, carbomer, oxidized sodium alginate, L-arginine ethyl ester dihydrochloride, theophylline, glycine fumarate, L-carnitine powder, stachyose, hydroxyethyl methylacrylate, tri(propylene glycol) diacrylate, ginkgo flavonol, polyhexamethylene biguanidine, povidone iodine, alcoholic extract of herba andrographitis, triethanolamine and de-ionized water. The hydrogel dressing prepared by the invention can achieve inhibitory rates 91% and 94% or above on pseudomonas aeruginosa and staphylococcus aureus separately, and the hydrogel dressing has a broad-spectrum antibacterial property and a durable antibacterial effect; and in addition, the hemostasis time of the dressing is just 9-18s and healing time is shorter than 10d, and healed regenerated skin has a smooth and delicate surface; therefore, the hydrogel dressing is excellent in wound healing capacity and quite good in healing effect.

Owner:林春梅

Adsorbent, cleansing agent, renal disease drug, and functional food

InactiveUS20110135561A1Increase valueImprove functionalityCarbon compoundsAntinoxious agentsPorous carbonTryptophan

Disclosed is an adsorbent including a porous carbon material which is produced from a plant-derived material having a silicon (Si) content of not less than 5 wt. % and which has a value of specific surface area determined by the nitrogen BET method of not less than 10 m2 / g, a silicon content of not more than 1 wt. %, and pore volumes determined by the BJH method and the MP method of not less than 0.1 cm3 / g. The adsorbent adsorbs indole, uric acid, adenosine, α-amylase, 3-methylindole, tryptophan, indicant, theophylline, inosine 5-monophosphate disodium salt, adenosine 5-triphosphate disodium salt, a fatty acid, a coloring matter, hydrophobic molecules, or an organic matter (for example, organic molecules or a protein) having a number average molecular weight of not less than 1×102 and less than 5×102.

Adsorbent, cleansing agent, renal disease drug, and functional food

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Owner:SONY CORP

Production process for caffeine

InactiveCN106083853AFast filteringFast dehydration rateOrganic chemistryFiltrationSeparating agent

The invention discloses a production process for caffeine. A catalyst is separated with formic acid, wherein as a separating agent of the catalyst, formic acid is easy to obtain and insoluble in a mother solution and is an ideal separating agent; theophylline is separated with the method of pressure filtration, wherein the pressure is 227 KPa, and compared with a common filtration mode, in pressure filtration, the filtering speed is high, and filter liquor is pure; the drying mode of crystals is changed into spin-drying with a centrifugal machine with the rotating speed of 5000 r / min, and compared with an air-drying mode, the rate of the water loss of centrifugal spin-drying is high, and thus the production efficiency can be greatly improved; secondary waste carbon is used for decoloring of a coarse caffeine solution, and compared with active carbon, the secondary carbon can reach the same decoloring effect while the process is more environmentally friendly and small in investment; secondary refining is additionally carried out, caffeine obtained after primary crystallization is subjected to secondary crystallization, and thus caffeine can be greatly purified.

Owner:安徽柒柒塑业有限公司

Preparation method of theophylline molecular surface printing material

InactiveCN103172804AOther chemical processesPolymer scienceMicroparticle

The invention discloses a preparation method of a theophylline molecular surface printing material, and relates to a molecular printing polymer. The preparation method comprises the following steps of: activating silica gel microparticles; connecting surface chemical bonds of silica gel microparticles with sulfydryl containing silane coupling agents; chemically grafting polyglycidyl methacrylate on surfaces of silica gel microparticles; modifying by 5-aminosalicylic acid; and preparing the surface molecular printing polymer of silica gel microparticles. According to the invention, high performance molecular printing polymer is prepared through a method of graft polymerization and crosslinking printing sequentially. The molecular surface printing material has special identifying selection and excellent combining affinity to theophylline.

Preparation method of theophylline molecular surface printing material

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Owner:ZHONGBEI UNIV +1

Modular aptametric sensors without covalently attached fluorophores

InactiveUS20060172320A1Improve abilitiesMicrobiological testing/measurementScreening processAptamerAnalyte

Modular aptameric sensors, transduce recognition events into fluorescence changes through allosteric regulation of non-covalent interactions with a fluorophore. These sensors consist of: (a) a reporting domain, which signals the binding event of an analyte through binding to a fluorophore; (b) a recognition domain, which binds the analyte; and (c) a communication module, which serves as a conduit between recognition and signaling domains. We tested recognition regions specific for ATP, FMN and theophylline in combinations with malachite green binding aptamer as a signaling domain. In each case, we obtained a functional sensor capable of responding to an increase in analyte concentration with an increase in fluorescence. Similar constructs that consist only of natural RNA could be expressed in cells and used as sensors for intracellular imaging.

Modular aptametric sensors without covalently attached fluorophores

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Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Theophylline homogeneous enzyme immunoassay kit and preparation method thereof

InactiveCN102253215AHigh sensitivityImprove stabilityBiological testingEnzyme immunoassaysImmuno detection

The invention aims to provide simple, rapid, high-sensitivity and full-automation theophylline drug concentration detection equipment, and a preparation method thereof. The invention provides a theophylline homogeneous enzyme immunoassay kit and a preparation method thereof. The preparation method comprises the following steps: synthesizing a theophylline immunogen; preparing a theophylline-resisting specific antibody; preparing an enzyme labeling conjugate; and determining the sample. The equipment provided by the invention has high sensitivity, and good stability and repetitiveness; the sensitivity can reach 0.1 mu g / mL which is far lower than theophylline clinical drug-used range of 10-20 mu g / mL; the average intraassay and interassay precision is less than 2.0%; and the sample recovery rate is 103.4+ / -1.55%. The equipment provided by the invention can be applied on an automatic biochemical analyzer, is simple in operation, can be used for carrying out high-flux rapid sample detection, and is suitable for clinical detection of conventional treatment drug concentration. The theophylline antibody provided by the invention has strong specificity, has no cross reaction on 31 kinds of tested conventional drugs and compounds in the drug cross reaction test, and is suitable for clinically inspecting the blood concentration of the theophylline.

Theophylline homogeneous enzyme immunoassay kit and preparation method thereof

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Owner:济南金域医学检验中心有限公司

6,5-fused aromatic ring systems having enhanced phosphodiesterase iv inhibitory activity

InactiveUS6075016ASuperior PDE IV inhibitory effectEnhanced inhibitory effectBiocideOrganic chemistryCombinatorial chemistryTheophylline

Owner:EURO-CELTIQUE SA

Beneficial effects of increasing local blood flow

ActiveUS9226909B2Increase ionic strengthReduce deliveryBiocidePeptide/protein ingredientsArginineInjury mouth

The present invention generally relates to the improvement of tissue health by increasing local blood flow. In some aspects of the invention, increased local blood flow is effected by the transdermal delivery of the nitric oxide precursor L-arginine and / or its derivatives alone, or optionally in conjunction with an adjunct such as theophylline. The transdermal delivery is effected, in certain embodiments through the means of a hostile biophysical environment, such as that created by a high ionic strength environment. Various pathological states caused by, or occurring in conjunction with, insufficient blood flow, can be treated using the systems and methods of the invention as described herein. In other embodiments, increased blood flow using the systems and methods of the invention may result in enhanced healing, for example, through greater availability of the constituents of the blood. Examples of conditions which may benefit from increased blood flow include, but are not limited to, erectile dysfunction, hair loss, female sexual dissatisfaction, sagging facial or other body tissue, peripheral vascular disease including claudication, neuropathy, skin ulcers, bone healing, wound healing, viral and bacterial infection, and skin grafting.

Owner:STRATEGIC SCI & TECH

Theophylline induction type gene expression system

InactiveCN106591309ADifficulty of SimplificationBacteriaMicroorganism based processesMicroorganismTheophylline

The invention discloses a theophylline induction-type gene expression system, which belongs to the technical field of microbial biomass. The system takes a composition-type strong promoter P43 as a basic component, merges a theophylline controlling element riboE1 with reconstructed interval zone length among an artificial SD element and a SD sequence and an initial code, constructs the theophylline induction-type gene expression element P43-riboE1, and clones a sequence to a bacillus subtilis expression vector pBSG, the induction expression carrier pBSG11 is constructed, host 168 bacterium is conversed, and high-level and high inductivity expression of exogenous gene under theophylline control is realized. The high-efficiency controllable recombination expression of report gene GFP, GUS and aspartase is realized by using the recombinant bacteria. Compared with inductive agents such as xylose and IPTG, the system has the advantages of no toxicity, and low cost, and has wide application space by taking theophylline as the gene expression system of the inductive agent.

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Owner:JIANGNAN UNIV

Stable water in oil aminophylline emulsions

InactiveUS20030050318A1Alleviate the conditionUndesirable crystal growth is preventedCosmetic preparationsBiocideTheophyllineWater in oil emulsion

A water in oil emulsion system and a process for preparing such a emulsion has been provided for topically applying aminophylline for reducing cellulite conditions.

Owner:WESTERN HLDG

Preparation method for artificial antigen of theophylline

ActiveCN103360488AAdvanced synthesis technologyStrong specificitySerum albuminGlutaric anhydrideImmune profiling

The invention provides a preparation method for an artificial antigen of theophylline. The preparation method comprises the following steps of: (a) preparing and detecting a hapten: reacting 5,6-diamido-1,3-dimethylurea pyrimidine (1) with glutaric anhydride to obtain the hapten containing carboxyl; (b) preparing and detecting the artificial antigen: combining the hapten with bovine serum albumin (BSA) by utilizing a carbodiimide method, so as to prepare the artificial antigen of the theophylline, namely theophylline-bovine serum albumin. According to the preparation method, the prepared artificial antigen of the theophylline can be subjected to animal immunization to obtain corresponding theophylline antibodies and can be used for researching various theophylline immunoassay methods, and a relatively convenient, fast and accurate way is provided for the detection of the theophylline.

Preparation method for artificial antigen of theophylline

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Owner:杭州博林生物技术有限公司

Method for preparing instant tea without alkaloid components including caffeine and theophylline etc.

InactiveCN102870926ATea extractionTea alkaloid content reductionInstant teaTheaflavin

The invention relates to a technological method for preparing instant tea without alkaloid components including caffeine and theophylline etc. The technological method belongs to the field of extraction, separation and purification of a tea (a green tea and a black tea). The tea is separated and purified through a macroreticular resin PIPO-00, an advanced asymmetric chromatographical idea is adopted, double-column sampling and chromatography at high pressure are carried out, the components with excitatory effects including the caffeine and the theophylline etc. in the tea are removed, and an instant tea product with functional health care components including either tea polyphenol or theaflavin etc. in the tea is obtained. The components including the caffeine and the theophylline are removed, and the functional health care components including the either tea polyphenol in the green tea or the theaflavin in the black tea etc. are preserved, the product can be instantly dissolved and convenient to use, dosage of the product is improved and range of crowds is enlarged, so that the instant tea is a health care product for patients of all ages and both sexes.

Owner:PI & PI BIOTECH

Method for extracting theophylline sodium salt or theophylline by styrene type macroporous resin

ActiveCN102344450AQuality improvementImprove extraction efficiencyOrganic chemistryBenzeneDesorption

The invention discloses a method for extracting theophylline sodium salt or theophylline from a theophylline sodium salt or theophylline mother solution by a styrene type macroporous resin adsorption method, which comprises the following steps: (1) regulating the pH value of the theophylline sodium salt or theophylline mother solution; (2) filtering the mother solution and removing suspended impurities in the mother solution; (3) adsorbing the mother solution by adsorption resin; (4) desorbing the adsorption resin after adsorption saturation by a desorbing agent to obtain a desorption solution; (5) regulating the pH value of the desorption solution, standing and crystallizing theophylline sodium salt or theophylline; (6) centrifugally filtering; and (7) drying to obtain solid theophylline sodium salt. The method provided by the invention has the advantages that the theophylline sodium salt or theophylline crude product has better quality, the operation safety is better, the extraction efficiency is higher, the extraction cost is low, and the method is more suitable for mass production and facilitates realizing automatic operation. With the method disclosed by the invention, the extraction cost of the theophylline sodium salt and theophylline can be reduced, the extraction yield of the theophylline sodium salt and theophylline is increased, and the competitiveness of enterprises is enhanced.

Owner:SUNRESIN NEW METERIALS CO LTD XIAN

Pig raising manure deodorization preparation

InactiveCN105148307AGuaranteed freshGuaranteed living environmentBiocideDisinfectantsPagoda treePumpkin seed

The invention discloses a pig raising manure deodorization preparation. The pig raising manure deodorization preparation is characterized by comprising, by weight, 5 parts of tourmaline powder, 5 parts of glyceryl behenate, 10 parts of stearic acid, 3 parts of theophylline, 3 parts of curcumin, 3 parts of citric acid, 20 parts of lotus leaves, 10 parts of dried tangerine or orange peel, 5 parts of camphor, 10 parts of clove, 5 parts of pumpkin seeds, 5 parts of garland chrysanthemum, 10 parts of licorice, 5 parts of camellia, 5 parts of portulaca oleracea, 3 parts of coptis chinensis, 5 parts of bitter gourd, 3 parts of pagoda tree pod, 3 parts of peppermint roots, 10 parts of chili leaves, 5 parts of tilia bark and 500 parts of distilled water. The pig raising manure deodorization preparation has the advantages that effects of effectively removing smelly substances in pig raising manure can be realized by the pig raising manure deodorization preparation which is a deodorant, the pig raising manure deodorization preparation further has a sterilization function, accordingly, survival environments can be guaranteed to a certain extent while odor of the manure is removed, and the air freshness can be kept; the pig raising manure deodorization preparation is made of raw materials which are easily available, and is low in production and service costs.

Owner:郎溪县凌达养猪专业合作社

Method for preparing theophylline sustained release

ActiveCN103239419AMiscible evenlyQuality improvementPharmaceutical delivery mechanismRespiratory disorderAdhesiveFluidized bed

The invention belongs to the technical field of medicines and relates to a method for preparing theophylline sustained release. The method comprises the following preparation steps: (1) adding a retardant into a wet type granulator, adding a solvent of the retardant to prepare an adhesive, and stirring and shearing at normal temperature; (2) adding theophylline, an adhesive and a filler and preparing a soft material; (3) replacing a 16-20-mesh stainless steel mesh in the granulator, and granulating through the granulator; and (4) pumping the wet granules into a fluidized bed for drying in a vacuum mode, granulating through a crushing granulator, mixing and laminating to obtain the theophylline sustained release by adding a lubricating agent. The theophylline sustained release can be released at a constant speed, the quality is stable, the pain of the asthmatic is safely, effectively and stably solved, the pain of a patient is relieved, the process is simple, and the process stability is high.

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Owner:REYOUNG PHARMA

Theophylline-based nitophenylpiperazine derivatives for enhancing aortic smooth muscle relaxation

InactiveUS20080064705A1Organic chemistryHeterocyclic compound active ingredientsHydrogenTheophylline

A substance for enhancing an aortic smooth muscle relaxation is provided. The substance is one selected from the group consisting of a compound of formula (I), a pharmaceutical acceptable therefrom and a solvate therefrom,wherein either of R1 and R2 is one of a hydrogen and a nitro group.

Theophylline-based nitophenylpiperazine derivatives for enhancing aortic smooth muscle relaxation

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Owner:KAOHSIUNG MEDICAL UNIVERSITY

364 results about "Theophylline" patented technology

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