27 results about "Muconic acid" patented technology

The present invention relates to novel homopolymers or copolymers derived from muconic or sorbic acid, to a method for preparing same, to a composition, in particular a cosmetic composition, comprising at least one homopolymer or copolymer derived from muconic or sorbic acid, to a method for treating keratin materials, in particular human keratin materials such as the skin or hair, implementing the application onto the materials of at least one homopolymer or copolymer derived from muconic or sorbic acid or a composition comprising at least one homopolymer or copolymer derived from muconic or sorbic acid; to a method for preparing diacids from homopolymers or copolymers derived from oxidative degradation, in particular by ozonolysis, and to novel diacid compounds derived from the degradation.

An electrocatalytic method includes passing current through a catalytic cathode in a reactor including an aqueous solution including the muconic acid, a supporting electrolyte, and an anode, so as to hydrogenate the muconic acid to yield a product including 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a mixture thereof. An electrocatalytic method includes passing current through a catalytic cathode in a reactor including an aqueous solution including an organic substrate, a supporting electrolyte, and an anode, so as to electrocatalytically convert the organic substrate, wherein the aqueous solution includes a fermentation broth including the organic substrate and including one or more catalyst poisons that reduce catalytic activity of the catalytic cathode; removing one or more catalyst poisons from the catalytic cathode to form a rejuvenated catalytic cathode; and reusing the rejuvenated catalytic cathode in the method.

The invention discloses a preparation method of bio-based trans, trans-muconic acid. Comprising the following steps: mixing a raw material containing galactose diacid with a catalyst, and reacting to obtain a product containing trans, trans-muconic acid; the catalyst is selected from at least one of ammonium paramolybdate, ammonium orthomolybdate, potassium heptamolybdate, sodium molybdate, sodium molybdate and molybdic acid. Compared with a traditional method for synthesizing trans, trans-muconic acid, the method provided by the invention has the advantages of simple steps, low cost and high conversion rate selectivity. Compared with traditional fossil energy-based raw materials, the reaction raw materials are derived from biomass, and the sustainable development view and the dual-carbon concept are met.

The invention discloses an extraction method of bio-based muconic acid, which comprises the following steps: inoculating preserved escherichia coli into a seed culture medium for activation culture to obtain a seed solution; inoculating the seed solution into a fermentation culture medium according to an inoculation amount of 5-10% to prepare a fermentation solution; carrying out preliminary plate frame filtration on the fermentation liquor to remove impurities such as large cell residues and the like, so as to obtain pretreated fermentation liquor; filtering the pretreated fermentation liquor through an ultrafiltration membrane to intercept impurities with molecular weight greater than a certain value, and concentrating muconic acid to obtain concentrated liquor; the collected concentrated solution is acidized, the pH is adjusted to be 1-2, and the solution used for acidification is a 20-36% concentrated hydrochloric acid solution. Then low-temperature cooling crystallization is carried out, the temperature is controlled to be 4-10 DEG C, the pressure is normal pressure, and muconic acid crystals are separated out; and dissolving a product obtained by acidification and crystallization in hot pure water at 70-90 DEG C, then cooling to 4-10 DEG C, crystallizing, filtering and drying to obtain a purified muconic acid product.

A genetically modified microorganism that can produce 3-hydroxyadipic acid and / or α-hydromuconic acid with a high yield; and a method of producing 3-hydroxyadipic acid and / or α-hydromuconic acid using the genetically modified microorganism, are disclosed. The genetically modified microorganism has an ability to produce 3-hydroxyadipic acid and / or α-hydromuconic acid, and has an enhanced enzymatic activity to catalyze a reaction to reduce 3-oxoadipyl-CoA to 3-hydroxyadipyl-CoA, wherein, in the genetically modified microorganism, a dicarboxylic acid excretion carrier function is deleted or decreased.

Described herein are materials and methods to generate beta-ketoadipates cost-efficiently and with reduced environmental impact from muconolactone. Advantageously, the described beta-ketoadipates, including dimethyl beta-ketoadipates, are more stable than traditional βKA and can be produced with a reduction in the amount of salt byproducts, by as much as half.

This invention relates to a preparation process of polymuconate salts and polymuconic acid derivatives in aqueous solution, wherein said process comprises the following steps: (a) reacting muconic acid precursor with aqueous basic solution to obtain muconate salt; and (b) adding an initiator to the muconate salt solution obtained from step (a) and operating at the determined temperature to obtain polymuconate salts.

Disclosed herein are methods for oxidative catalytic depolymerization of polystyrene (PS) can produce benzoic acid, but the annual consumption of benzoic acid is about 40 times lower than PS. For this catalytic oxidation method to be a viable means to manage PS waste, benzoic acid should be converted to higher-volume chemicals. We demonstrate a hybrid chemical and biological process that uses PS as feedstock for production of adipic acid, a high-volume co-monomer for nylon 6,6 via benzoic acid. Mn / Br co-catalyzed autoxidation of PS to benzoic acid proceeds with a yield of up to 94% in a solvent mixture of benzoic acid and water. The PS-derived benzoic acid undergoes bioconversion at near-quantitative yield to muconic acid, which is readily converted to adipic acid through catalytic hydrogenation.

Disclosed herein are methods and compositions of matter and processes for synthesizing caprolactam for nylon-6 production form muconic and adipic acids. A transition metal catalyst (typically ruthenium) on an acidic support (typically niobia) was synthesized to catalyze the amidation and cyclization to caprolactam.

The present application belongs to the technical field of thermoplastic polyurethane elastomer, and relates to a UV-resistant bio-based thermoplastic polyurethane and a preparation method thereof.The UV-resistant bio-based thermoplastic polyurethane comprises the following components in parts by weight: bio-based polyester diol 35-70 parts; diisocyanate 15-55 parts; chain extender 2-15 parts; antioxidant 0.2-1 part; catalyst 0.001-0.05 part; the bio-based polyester diol is obtained by polycondensation of dicarboxylic acid and dihydric alcohol; the dicarboxylic acid comprises biomass muconic acid.The present application uses bio-based muconic acid with ultraviolet absorption function to synthesize bio-based polyester diol, realizes the characteristics of bio-based and UV resistance, and the thermoplastic polyurethane obtained in this way has good ultraviolet light absorption function and good transparency, has a high tensile strength retention rate after ultraviolet aging, and can be used in the fields of ultraviolet protection coating, building materials and sunscreen fabric.

The present invention relates to novel homopolymers or copolymers derived from muconic or sorbic acid, to the method for preparing same, to a non-cosmetic composition comprising at least one homopolymer or copolymer derived from muconic or sorbic acid, and to a method for treating a non-keratinized material with at least one homopolymer or copolymer derived from muconic or sorbic acid, or with a composition comprising at least one such polymer. The invention further relates to a method for breaking down such polymers, as well as to diacid derivatives that can be obtained by such a method.

Disclosed are: a genetically modified microorganism capable of producing 3-hydroxyhexanedioic acid and / or (E)-hex-2-enedioic acid at a high yield; and a production method for 3-hydroxyhexanedioic acid and / or (E)-hex-2-enedioic acid using said genetically modified microorganism. The genetically modified microorganism has: the ability to produce 3-hydroxyhexanedioic acid and / or (E)-hex-2-enedioic acid; an enhanced enzyme activity that catalyzes a reaction that reduces 3–oxoadiphyl-CoA and generates 3–hydroxyadiphyl–CoA; and has lost or reduced the dicarboxylic acid discharge carrier function.

Disclosed is a novel genetically modified microorganism showing improved yields of 3-hydroxyadipic acid and / or α-hydromuconic acid. The genetically modified microorganism is a microorganism having an ability to produce 3-hydroxyadipic acid and / or α-hydromuconic acid, in which the reaction to generate malic acid from oxaloacetic acid is enhanced, and the reaction to generate acetyl-CoA from pyruvic acid is enhanced. In addition, the reaction to generate carbon dioxide from formic acid is enhanced.

Title: USE OF POLYMERS DERIVED FROM MUCONIC OR SORBIC ACID, PROCESS FOR PROCESSING KERATINIC MATERIALS, POLYMER AND COMPOSITION The present invention relates to new homopolymers or copolymers derived from muconic or sorbic acid, their preparation process, a composition, in particular a cosmetic composition, comprising at least one homopolymer or copolymer derived from muconic or sorbic acid, a process for treating keratinic materials, in particular human materials such as skin or hair, involving the application to said materials of at least one homopolymer or copolymer derived from muconic or sorbic acid or of a composition comprising at least one homopolymer or copolymer derived from muconic or sorbic acid; a process for preparing diacids from homopolymers or copolymers resulting from oxidative degradation, in particular by ozonolysis, and new diacid compounds resulting from said degradation.

The invention belongs to the technical field of leaf spray, and particularly discloses leaf spray containing muconic acid and application of the leaf spray. The foliar spray is prepared from the following raw material components: muconic acid, ethanol, calcium eicosylbenzene sulfonate and cetylammonium bromide. The foliar spray can effectively inhibit pathogenic bacteria and / or prevent and treat plant diseases caused by the pathogenic bacteria, especially diseases caused by botrytis cinerea.

The present invention relates to novel homopolymers or copolymers resulting from muconic or sorbic acid, to their process of preparation, to a composition, in particular a cosmetic composition, comprising at least one homopolymer or copolymer resulting from muconic or sorbic acid, to a method for the treatment of keratin materials, in particular human keratin materials, such as the skin or head hair, employing the application, to said materials, of at least one homopolymer or copolymer resulting from muconic or sorbic acid or of a composition comprising at least one homopolymer or copolymer resulting from muconic or sorbic acid, to a process for the preparation of diacids from the homopolymers or copolymers resulting from oxidative degradation, in particular by ozonolysis, and to new diacid compounds resulting from said degradation.

The present invention relates to novel homopolymers or copolymers resulting from muconic or sorbic acid, to their process of preparation, to a composition, in particular a cosmetic composition, comprising at least one homopolymer or copolymer resulting from muconic or sorbic acid, to a method for the treatment of keratin materials, in particular human keratin materials, such as the skin or head hair, employing the application, to said materials, of at least one homopolymer or copolymer resulting from muconic or sorbic acid or of a composition comprising at least one homopolymer or copolymer resulting from muconic or sorbic acid, to a process for the preparation of diacids from the homopolymers or copolymers resulting from oxidative degradation, in particular by ozonolysis, and to new diacid compounds resulting from said degradation.

The invention discloses a method for co-culturing and synthesizing muconic acid by escherichia coli, an engineering bacterium E.coli W6 delta C and an engineering bacterium E.coli MA1 delta C are constructed, the engineering bacterium E.coli W6 delta C and the engineering bacterium E.coli MA1 delta C are co-cultured and fermented to produce and accumulate muconic acid, the upstream path engineering bacterium E.coli W6 delta C is loaded with a plasmid pUC57-Ppdc-aroGELAC-trpEfbr, and the downstream path engineering bacterium E.coli MA1 delta C is a tryptophan knockout strain and is loaded with a pRSFDuet-antABC-catA gene insertion type plasmid. According to the invention, two escherichia coli genetic engineering strains with complementary functions are constructed, and a co-culture strategy is adopted, so that muconic acid synthetic route is modularly split, and continuous and efficient conversion from glucose to a target product is realized.

The present invention relates to a method for determining the presence of lung cancer in a subject. The method comprises: (i) determining the level of one or more biomarkers in a sample from the subject; and (ii) comparing the level of said one or more biomarkers with the level of said one or more metabolites in a control sample to determine whether lung cancer is present in the subject. The biomarkers are selected from: 2-methoxyestrone 3-sulfate, testosterone glucuronide, androsterone glucuronide, 5a-dihydrotestosterone sulfate, corticrocin, octanoic acid, beta-citryl-L-glutamic acid, 2-hydroxymuconic semialdehyde, 5,6,11-dodecatriynoic acid, creatine riboside, 3-(Carboxymethyl)-3-hydroxypentanedioic acid, adenosine phosphosulfate, 7,8-dihydroneopterin 3'-phosphate, cis,cis,cis-10,13,16-Docosatrienoyl-CoA, inosine, N-(2,4-Dinitrophenyl)-2,4-dinitroaniline, prostaglandin M, pentadecenoic acid, PE(22:0 / P-18:0), carbamoyl phosphate, 2-hydroxy-3-oxohexanedioic acid, galactosylceramide (d18:1 / 22:0) and PE-NMe2(18:1(11Z) / 22:1(13Z)).

The application provides an Escherichia coli (E. coli) recombinant strain for producing 2-pyrone-4,6-dicarboxylic acid. Escherichia coli The recombinant strain is obtained by overexpressing an exogenous 3-dehydroshikimic acid dehydrase gene on the genome of a 3-dehydroshikimic acid-producing recombinant strain, or further overexpressing a protocatechuate-4,5-dioxygenase gene, or further overexpressing a 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase gene, so as to realize high-efficiency de novo synthesis of 2-pyrone-4,6-dicarboxylic acid. The strain utilizes an inorganic salt culture medium, takes glucose as a carbon source, and produces 2-pyrone-4,6-dicarboxylic acid through batch feeding fermentation, so that the production cost is low, and the above-mentioned recombinant strain does not contain a plasmid and has high genetic stability.

The present invention makes it possible to improve the production yield of 3-hydroxyhexanedioic acid, (E)-hex-2-enedioic acid, and / or hexanedioic acid while reducing the by-production of acetic acid by enhancing the function of isocitrate lyase in a microorganism capable of producing 3-hydroxyhexanedioic acid, (E)-hex-2-enedioic acid, and / or hexanedioic acid. The present invention further makes it possible to improve the production yield of 3-hydroxyhexanedioic acid by increasing the expression level of YnfM or a homolog thereof in a microorganism capable of producing 3-hydroxyhexanedioic acid.

This invention discloses a method for ring-opening the aromatic ring of lignin, belonging to the field of biomass resource utilization technology. The method includes: adding lignin to a solvent, then adding an enzyme catalyst and an oxidant, reacting, and centrifuging to obtain the ring-opened product. This invention utilizes a system of oxidant and organic carboxylic acid ester solvents, where lipase catalyzes the in-situ generation of peroxycarboxylic acid, further catalyzing the ring-opening of phenolic lignin. The enzyme-catalyzed and controllable reaction process achieves a catalytic efficiency of up to 99%, with high yields of mucoconic acid products and few byproducts, providing a new technical route for the effective utilization of lignin resources to produce high-value-added chemicals.

The invention belongs to the technical field of plant growth regulators, and particularly discloses a muconic acid-containing plant growth regulator and a preparation method thereof. The plant growth regulator is prepared from the following raw material components: muconic acid, beta-aminobutyric acid and bacillus agave fermentation liquor. After the prepared plant growth regulator is used, the stress resistance of crops can be remarkably improved, the saline-alkali resistance of the crops is improved, and meanwhile, the plant growth regulator also has a synergistic interaction effect in the aspect of crop disease prevention.

The objective is to improve the productivity of 3-hydroxyadipic acid, α-hydromuconic acid, and / or adipic acid while reducing the by-product of acetic acid in a method for producing 3-hydroxyadipic acid, α-hydromuconic acid, and / or adipic acid using microorganisms. [Solution] A genetically modified microorganism capable of producing 3-hydroxyadipic acid, α-hydromuconic acid, and / or adipic acid, in which the function of isocitrate lyase is enhanced.

A method for determining the presence of lung cancer in a subject comprises: (i) determining the level of one or more biomarkers in a sample from the subject; and (ii) comparing the level of said one or more biomarkers with the level of said one or more metabolites in a control sample to determine whether lung cancer is present in the subject. The biomarkers are selected from: 2-methoxyestrone 3-sulfate, testosterone glucuronide, androsterone glucuronide, 5a-dihydrotestosterone sulfate, corticrocin, octanoic acid, beta-citryl-L-glutamic acid, 2-hydroxymuconic semialdehyde, 5,6,11-dodecatriynoic acid, creatine riboside, 3-(carboxymethyl)-3-hydroxypentanedioic acid, adenosine phosphosulfate, 7,8-dihydroneopterin 3’-phosphate, cis,cis,cis-10,13,16-docosatrienoyl-CoA, inosine, N- (2,4-dinitrophenyl)-2,4-dinitroaniline, prostaglandin M, pentadecenoic acid, PE(22:0 / P-18:0), carbamoyl phosphate, 2-hydroxy-3-oxohexanedioic acid, galactosylceramide (d18:1 / 22:0) and PE-NMe2(18:1(11Z) / 22:1(13Z)). The biomarkers may be detected using mass spectrometry, or by enzyme-linked immunosorbent assay (ELISA). Preferably, the sample is a urine sample.