48 results about "Diacetylene" patented technology

The present application relates to a diacetylene compound represented by formula (I), or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising same, and a use of the compound, the pharmaceutically acceptable salt thereof, and the pharmaceutical composition. The compound, or the pharmaceutically acceptable salt thereof and the pharmaceutical composition comprising same can be used for preparing a drug for treating or relieving neuroinflammation and neurodegenerative diseases.

The invention relates to a diyne functionalized covalent organic framework material as well as a preparation method and application thereof, and the diyne functionalized covalent organic framework material is synthesized by taking 4, 4 ', 4', 4 ''-(pyrene-1, 3, 6, 8-tetrayl) tetraphenylamine and 5, 5 '-(butyl-1, 3-diyne-1, 4-diyl) diisophthalaldehyde as construction units and adopting a Schiff base reaction. The dialkynyl functionalized covalent organic framework material disclosed by the invention has good chemical stability and can be used as a carrier to controllably grow silver nanoparticles through metal coordination to obtain a composite material, and the composite material shows excellent catalytic activity and cycling stability in a 4-nitrophenol reduction reaction catalyzed by sodium borohydride; therefore, the method has important application potential in the fields of environmental restoration, green chemistry and the like.

The application discloses a method for treating organic pollutant wastewater by using manganese monoxide-graphite diacetylene nano-confined catalytic material to activate persulfate, the method is to degrade and treat organic pollutant wastewater by using manganese monoxide-graphite diacetylene nano-confined catalytic material as a catalyst for activating persulfate, and the nano-confined catalytic material comprises graphite diacetylene nanosheets, and manganese monoxide nanoparticles are confined between the layered structures of the graphite diacetylene nanosheets.The method has the advantages of rich active sites, fast electron transfer and stable structure, so that the catalytic degradation system is not only high in efficiency, but also strong in adaptability, and shows good degradation effect on various organic pollutants, and has the advantages of simple process, convenient operation, high treatment efficiency, good removal effect, strong adaptability, green environmental protection and the like, and has important promoting significance for deep purification of organic pollutant wastewater.

The application discloses a method for treating antibiotic wastewater by using a graphdiyne / ferrous indium sulfide nanocomposite to activate persulfate, and the method is characterized by using the graphdiyne / ferrous indium sulfide nanocomposite as a catalyst to activate persulfate for degrading and treating antibiotic wastewater, wherein the graphdiyne / ferrous indium sulfide nanocomposite comprises ferrous indium sulfide nanoparticles, and the nanoparticles are loaded with graphdiyne nanosheets. The method for treating antibiotic wastewater by using the graphdiyne / ferrous indium sulfide nanocomposite to activate persulfate uses the graphdiyne / ferrous indium sulfide nanocomposite as a catalyst, wherein the nanocomposite has many reactive sites, high catalytic activity and good stability, can efficiently activate persulfate with a smaller amount of catalyst, can efficiently remove antibiotics in wastewater, and has the advantages of low cost, high treatment efficiency, good removal effect, green environmental protection and the like, and therefore, the method has important significance for effectively purifying antibiotic wastewater, has high use value and good application prospect.

The application provides a preparation method and device of a graphdiyne powder material, and the method comprises the following steps: under the action of microwaves, the graphdiyne powder is prepared through a solution homogeneous system and in combination with a flow continuous growth process. The application realizes the large-batch continuous preparation of the graphdiyne powder under the condition of no substrate by using the microwave method, and overcomes the technical difficulty that the graphdiyne powder is difficult to continuously mass-produce in a homogeneous solution. The reaction time is short, the yield is high, the operation is simple, and the two-dimensional graphdiyne nanosheet with uniform sheet diameter is prepared.

The application relates to the technical field of tumor marker detection, in particular to a sensor for detecting a tumor marker EpCAM as well as a preparation method and application thereof. The sensor is obtained by self-assembly of a compound of formula 1) and a compound of formula 2) into diacetylene liposomes, then a fluorescent dye-labeled EpCAM aptamer is combined with the diacetylene liposomes through electrostatic interaction to obtain the sensor; the sensor can be used as an activatable fluorescent sensor to sensitively and selectively detect EpCAM and has the effect of fast response, and can realize rapid and sensitive analysis and detection of EpCAM at the water solution level, the living cell level and the animal level; formula 1); formula 2).

The invention discloses a preparation method of a chiral dendronized diacetylene acid molecule and a supramolecular chiral assembly of the chiral dendronized diacetylene acid molecule, and relates to the field of intelligent chiral materials.The preparation method comprises the steps that firstly, tree-shaped alkoxy ether is combined with PCDA through lysine, the tree-shaped alkoxy ether serves as a hydrophilic element, lysine serves as a chiral source and can provide a large number of hydrogen bonds, the PCDA serves as a hydrophobic element, and the supermolecular chiral assembly of the chiral dendronized diacetylene acid molecule is obtained; chiral dendronized diacetylene acid molecules are designed and synthesized; then, supermolecule chiral assembly is carried out through driving of non-covalent interaction, and supermolecule chiral assembly is regulated and controlled through temperature and light; furthermore, the supramolecular chiral assembly is subjected to optical topological polymerization reaction to prepare the valence-donating chiral polymer. The invention opens up a new way for creating a novel intelligent chiral nano material with a special structure and excellent characteristics.

The invention provides a conductive agent precursor, an electrode plate and a battery, the conductive agent precursor comprises a 1, 3-butadiyne derivative, and the 1, 3-butadiyne derivative comprises aryl and / or aliphatic hydrocarbon. When the conductive agent precursor provided by the invention is applied to the electrode plate, the resistance of the electrode plate is relatively small, so that the impedance of the battery is relatively small.

The present invention belongs to the field of polymer synthesis and materials, and specifically relates to an oxazolidinone polymer, its preparation method, and application. The present invention uses a diacetylene monomer, a dialdehyde monomer, carbon dioxide, and a monoamine as raw materials, and reacts in the presence of cuprous iodide and a polar aprotic solvent to obtain the polymer. The oxazolidinone polymer has the following general structural formula: R1, R2, and R3 are the same or different organic groups. The above-mentioned synthesis method has readily available reaction raw materials, mild reaction conditions, and does not require the use of precious metal catalysts, which greatly reduces the reaction cost. In addition, the reaction has a wide range of substrate applicability and good functional group compatibility, and a variety of functional groups can be introduced. The oxazolidinone polymer prepared by the present invention has good processability, high thermal stability, and aggregation-induced emission properties, and has important application value in optical plastics, biomedical materials, optical anti-counterfeiting, fluorescence sensing, and other aspects.

This invention relates to a dual-responsive poly(diacetylene) hybrid nanozyme, its preparation, and its application, belonging to the field of pharmaceutical technology. The dual-responsive poly(diacetylene) hybrid nanozyme of this invention uses poly(4,6-diynyl sebacate) as a template polymer, wherein a metal oxide with Fenton-like catalytic activity is complexed and linked to the carboxyl group of the template polymer. The dual-responsiveness of the nanozyme to pH and reactive oxygen species in this invention enables the hybrid nanozyme to exhibit precisely regulated catalytic activity. In an acidic environment, the protonation of PDDA induces the nanozyme to self-assemble into fibrous aggregates, significantly enhancing its retention capacity in the stomach (especially at sites of inflammation). Acidic pH and elevated hydrogen peroxide levels jointly activate the catalytic antibacterial activity of the nanozyme, thereby achieving antibacterial and antitumor effects.

The present application relates to a kind of dendritic phenylacetylene crosslinking agent and its preparation method and application.The preparation method carries out amidation reaction with dendritic active ester and amino alcohol, and generates intermediate product;Intermediate product is esterified with diacetylene benzoic acid and catalyst, and dendritic phenylacetylene crosslinking agent is generated.The present application is mainly with dendritic phenylacetylene monomer and dendritic phenylacetylene crosslinking agent, utilizes the good water-soluble and temperature sensitivity of crosslinking agent, can be realized monomer temperature sensitive aggregation under the condition of no additive, and then in situ crosslinking polymerization obtains uniform dispersion dendritic helical polyphenylacetylene micro-nano gel, the gel has dynamic regulation, and exhibits good biocompatibility, can have potential application value in the field such as biosensing, chiral drug delivery, biological tissue engineering.

The invention discloses a diacetylene topological chemical reaction method which comprises the following steps: spin-coating a diacetylene solution on a substrate to form a coating film; and irradiating the coating film by adopting an infrared light source, and reacting to generate polydiacetylene. Compared with side reaction and degradation caused by the fact that high-energy rays enable the material to enter an electron excitation state and material fragmentation caused by severe spatial change of molecules under high polymerization, mid-infrared light vibration excitation in the method serves as a means capable of triggering molecular vibration under an electron ground state, and under the mild condition, the mid-infrared light can be used as a means capable of triggering molecular vibration under the electron ground state. Therefore, various bad effects generated in the electron excitation state can be avoided.

The invention provides a conjugated polymer sheet layer-single layer two-dimensional material heterostructure with polarization response, the heterostructure is composed of a polydiacetylene conjugated polymer sheet layer and a single layer transition metal disulfide compound, and the polydiacetylene conjugated polymer sheet layer is obtained by depositing a dispersion liquid on a polydimethylsiloxane polymeric membrane; the single-layer transition metal dichalcogenide is obtained by mechanically stripping a corresponding block, and the heterostructure is obtained through dry transfer. The heterostructure has the following beneficial effects that the optical behavior of the two-dimensional material can be regulated and controlled based on energy band engineering, and the optical property of the two-dimensional material is influenced; the polarization optical characteristic of the two-dimensional material can be regulated and controlled based on the polarization response characteristic of the highly-oriented polydiacetylene conjugated polymer sheet layer, and the polarization luminescence of the two-dimensional material in the heterostructure can generate optical polarization behavior inversion under different wavelengths; based on the polarization switchable characteristic of the system, the system is expected to be applied to polarized light detection.

The application discloses a kind of crosslinking strategy construction polymer conversion wave-absorbing ceramic and its preparation method and application, belong to ceramic technical field, solve the problem of uneven dispersion of material caused by the preparation method in the prior art.The method comprises the following steps: the hyperbranched polyborosilazane precursor containing silicon-hydrogen bond and poly(diacetylene) dimethylsilane containing alkyne group are uniformly dissolved in anhydrous tetrahydrofuran according to the mass ratio of 5-20:1, platinum (0) -1,3-divinyl-1,1,3,3-tetramethyldisiloxane is added, and the anhydrous tetrahydrofuran is removed after overnight reaction at 45-60℃ temperature condition, to obtain a polymer precursor;The polymer precursor is crosslinked at 400℃, ground into powder, pressed into embryo and pyrolyzed at 1400℃, to obtain a polymer conversion wave-absorbing ceramic.The preparation method provided by the application uniformly mixes and crosslinks two kinds of polysilane at the molecular level to obtain a new polymer precursor, and pyrolyzes at high temperature to prepare a wave-absorbing ceramic with uniform dispersion of structural components, achieving a more stable effect.

The application discloses a method for synthesizing (R)-( - )-1,3-butanediol by a one-step method of diketene, which uses a chiral ruthenium complex as a catalyst and a Bronsted acid as an assistant to make the diketene react by a one-step method under certain temperature and hydrogen pressure conditions to obtain (R)-( - )-1,3-butanediol. The method solves the problems of high cost, large catalyst consumption and difficult product separation in the prior art for preparing (R)-( - )-1,3-butanediol, and can asymmetrically hydrogenate the carbonyl group of the substrate diketene at low cost and with a small amount of catalyst, simultaneously reduces the ester group and opens the ring to obtain (R)-( - )-1,3-butanediol. The method has simple reaction operation and simple catalyst preparation, the yield of the target product and ee value are both above 98%, meanwhile, the catalyst can be repeatedly used, the cost is greatly reduced, and the method has the potential for industrial application.

The application discloses application of hydrogen-substituted graphdiyne in adsorption and removal of gaseous elemental mercury, and belongs to the technical field of nano adsorption materials. The application of hydrogen-substituted graphdiyne in adsorption and removal of gaseous elemental mercury. It is found that the hydrogen-substituted graphdiyne adsorbent has a large conjugated pi bond, an oversized pore structure and a high-activity diacetylene bond, and through coupling and electron transfer (Hg 0 → hydrogen-substituted graphdiyne) of H1s and C2p in the rich diacetylene bond of the hydrogen-substituted graphdiyne with the Hg5d electron layer of an adsorbed mercury atom, high-efficiency capture of Hg 0 is realized, and conversion of Hg 0 into Hg 2+ is realized without an additional oxidant.

The present disclosure relates to a polydiacetylene-based compound for detecting cyanide ions, a composition including the same, and a chemical sensor, and more particularly, to a polydiacetylene-based compound, which is a polymer of a self-assembly of diacetylene monomers represented by the following Chemical Formulas 1 and 2, a composition including the same, and a chemical sensor.(Chemical Formulas 1 and 2 are as defined in claim 1.)

The invention belongs to the technical field of wastewater treatment, and particularly relates to a heavy metal wastewater treatment agent and a preparation method thereof. The preparation method comprises the following steps: screening ionic rare earth tailings to obtain coarse-grained particles rich in quartz components, carrying out alkali fusion activation and hydrothermal crystallization to obtain analcime, grafting diethynyl to the surface of analcime by using a silane coupling agent, and finally carrying out a click reaction between alkynyl and azido to obtain the modified analcime. An azido Schiff base quaternary ammonium salt compound containing tertiary butyl, quaternary ammonium salt, Schiff base, nitrile group and a stereostructure heptyl ring is grafted on the surface of analcime, and the tertiary butyl, quaternary ammonium salt, organic silicon, triazole group and nitrile group on the surface of the analcime form a good hydrophilic and hydrophobic amphoteric structure, so that the surface activity of the analcime is effectively improved; heavy metal ions are promoted to approach the surface of the zeolite material, so that the heavy metal ion adsorption effect is improved.

The application discloses a preparation method of a large-diameter graphite diacetylene powder material. The large-diameter (5-10 mu m) graphite diacetylene powder material with a two-dimensional nanosheet structure is prepared by adopting a substrate-free system combined with a microwave reaction. Unlike the graphite diacetylene film material prepared in the prior art, the graphite diacetylene powder material has a wider application in ion batteries, electrocatalysis, DNA detection and the like.

The application provides a method for preparing beta-butyrolactone through asymmetric hydrogenation of diacetylene ketone, which is prepared through catalyzing asymmetric hydrogenation of diacetylene ketone under a hydrogen atmosphere by using a metal active component and a pyridine ring phosphine ligand as a catalyst. The method uses a hydroxyl-containing nitrogen heterocyclic phosphine ligand as a ligand, and a metal such as palladium, rhodium or ruthenium as an active metal, so that the conversion rate and selectivity of the reaction are improved, the stability of the catalyst is good, and the catalyst can be used multiple times. The synthesis route of the catalyst used in the method is short, the yield is high, the number of times of reusing is large, and the method has a good cost advantage.

The invention relates to a silicon-hydrogen-terminated silicon-containing aryne resin and a preparation method and application thereof, the structural formula of the silicon-hydrogen-terminated silicon-containing aryne resin is as follows: in the formula, R1 and R2 are respectively and independently CH3, CH2 = CH, H or phenyl; n is equal to 1-9. The preparation method comprises the following steps: firstly, carrying out Grignard reaction on 1, 3-diacetylene benzene and a Grignard reagent to obtain a compound 1 as shown in a formula I; carrying out polymerization reaction on the compound 1 and a compound 2 as shown in a formula II to obtain a compound 3 as shown in a formula III; and then carrying out reduction reaction on the compound 3 and lithium aluminum hydride to obtain the silicon-hydrogen-terminated silicon-containing aryne resin. Compared with the prior art, the silicon-hydrogen-terminated silicon-containing aryne resin prepared by the invention has excellent heat resistance, has extremely high thermal decomposition temperature of 5% of cured substance weight loss in nitrogen and air, has excellent processability and has an extremely wide processable temperature window.

The invention belongs to the technical field of ion exchange membranes, and provides a porous carbon material reinforced ion exchange membrane and a preparation method thereof. The Raman signal spectrum of the porous carbon material enhanced ion exchange membrane has a butadiyne signal peak at 2100 + / -100 cm < 1 >, and the preparation method comprises the following steps: step 1, dissolving ion exchange resin in a solvent, and uniformly stirring; 2, dissolving an organic functional precursor rich in terminal alkyne in the solution in the step 1, and uniformly stirring; 3, adding copper salt into the solution in the step 2, and stirring for reaction to obtain a membrane casting solution; step 4, casting the membrane casting solution into a membrane preparation mold, and carrying out heat treatment to remove the solvent, so as to obtain a membrane material; and 5, carrying out ion exchange on the membrane material to obtain the porous material enhanced ion exchange membrane. The porous carbon material enhanced ion exchange membrane is mild in synthesis condition and simple in process, and the obtained product is high in ionic conductivity, high in mechanical strength, low in swelling property and low in gas permeability.

An aminochalcone-diacetylene compound of Formula 1A:wherein R1 and R2 are independently selected from H and C1-C3 alkyl, A denotes a linkage connecting the chalcone and diacetylene units, m and n are independently integers in the range of 2 to 18, and the corresponding protonated form / ammonium salt of Formula 1B:wherein X is a counter anion. The disclosure further discloses the corresponding chromatic polydiacetylenes and polydiacetylenes-based sensors for detecting ammonia.

This pattern formation method comprises: a film formation step for attaching a diacetylene derivative-containing substance to a substrate to form a film of the diacetylene derivative-containing substance on the substrate; a polymerization step for causing a polymerization reaction of the diacetylene derivative in at least a portion of the film of the diacetylene derivative-containing substance to generate a polymer of the diacetylene derivative on the substrate; and a removal step for removing the film of the diacetylene derivative-containing substance formed on the substrate to form a pattern of the polymer of the diacetylene derivative on the substrate.

The present application relates to a kind of diacetylene functionalized covalent organic framework material and its preparation method and application, to 4,4',4'',4'''-(pyrene-1,3,6,8-tetrayl) tetraphenylamine, 5,5'- (but-1,3-diethynyl-1,4-diyl) diisophthalaldehyde as building unit, synthesis using Schiff base reaction.The diacetylene functionalized covalent organic framework material of the present application has good chemical stability, and can be used as carrier by metal coordination effect Controllable growth silver nanoparticles to obtain composite material, the composite material in sodium borohydride catalytic 4-nitrophenol reduction reaction has shown excellent catalytic activity and cycle stability, thus has important application potential in the field such as environmental remediation and green chemistry.

The application discloses a kind of sulphur-containing phthalimide alkenyl chloride compounds as shown in formula (3) and synthesis method thereof, with diacetylene as shown in formula (1) and phthalimide sulphur chloride as shown in formula (2) as reaction raw material, without any catalyst additive, reaction obtains sulphur-containing phthalimide alkenyl chloride compound.The application has mild reaction condition, raw material is cheap and easy to obtain, reaction operation is simple, yield is higher, without any catalyst additive in reaction, it is economical and practical, and friendly to environment;Reaction substrate is easy to prepare;Reaction efficiency is high after reaction amplification.The sulphur-containing phthalimide alkenyl chloride compound described in the application can be used to prepare polypeptide binding reagent.The application also discloses polysulfide binding peptide compound obtained by using the sulphur-containing phthalimide alkenyl chloride compound as shown in formula (3) and synthesis method thereof.The application has wide application prospect and practical value.

The application discloses a double-crosslinked hydrogel microneedle patch, which comprises a substrate layer and a needle tip part, wherein the needle tip part is made of an active oxygen responsive polypeptide prodrug, an ester bond functionalized small molecule prodrug, a polypeptide diacetylene and a double bond functionalized macromolecule, and the active oxygen responsive polypeptide prodrug, the ester bond functionalized small molecule prodrug and the polypeptide diacetylene are loaded on the double bond functionalized macromolecule through coupling covalent action; the active oxygen responsive polypeptide prodrug and the ester bond functionalized small molecule prodrug release drug molecules slowly through responding to an active oxygen microenvironment and ester bond hydrolysis respectively. The needle tip of the microneedle patch obtained by the application has good mechanical properties and can break through the cuticle barrier of the skin; on the basis of the above-mentioned physical properties, the needle tip still retains the cell activity of the bioactive polypeptide; in addition, the selected polypeptide type of the application can also inhibit the expression of fibrosis related proteins of cells, and thus an unexpected technical effect is achieved.

Methods, systems, and devices for depositing carbon conducting films by atomic layer deposition are described. For instance, a device may react a first precursor with a base material to form a carbon compound on a material, where the first precursor is an acetylene, a diacetylene, a tri-acetylene, a polyacetylene, an alkene, or an arene and includes at least one germanium, silicon, or tin. Additionally, the device may react a second, carbon-containing precursor with the carbon compound to form a layer on the base material.

The application discloses a method for diacetylene topological chemical reaction, which comprises the following steps: spin-coating a diacetylene solution on a substrate to form a coating film; and irradiating the coating film with an infrared light source to generate polydiacetylene through reaction. Compared with the side reactions and degradation caused by high-energy rays which make materials enter an electronic excited state, and the material fragmentation caused by the violent spatial change of molecules under high polymerization, the mid-infrared light vibration excitation in the method can be used as a means for initiating the vibration of molecules in an electronic ground state, and can be more widely close to a potential energy surface under mild conditions, so that various adverse effects generated in the electronic excited state can be avoided.

This invention discloses a method for photoreactive synthesis of graphene, belonging to the field of graphene material technology. The method uses 1,2-bis(4-pyridyl)butadiyne as a reactant, which is ground and then subjected to solid-state polymerization under mercury lamp irradiation to obtain a brown solid. The resulting brown solid is then washed with dichloromethane until it becomes colorless, clear, and transparent. After ultrasonication and drying, graphene is obtained. Compared with traditional methods, this invention eliminates the need for high pressure to compress intermolecular distances, avoiding the problems of complex processes, high energy consumption due to high pressure, difficulty in obtaining equipment, and high production costs. This invention features a simple preparation method, a concise synthesis route, a reliable process, low energy consumption, readily available raw materials and equipment, and low production costs, making it suitable for large-scale production.