205 results about "Colorimetric sensor" patented technology

A system for determining the level of an analyte in a physiological fluid of a live individual is described. A wearable sensor periodically obtains data representative of the level of the analyte and has a passive RFID tag that stores the data. A receiver wirelessly interrogates the sensor with an RF interrogation signal. The RFID tag modulates or otherwise modifies the wireless interrogation signal using the data and the receiver receives back the modulated or otherwise modified interrogation signal and extracts the data from it. The receiver then determines, from the data, the level of the analyte in the fluid. The sensor may be a photometric or colorimetric sensor or an electrochemical sensor. The receiver may be, or be incorporated into, a hand-held device, a portable device, a PDA, a mobile telephone, or a laptop computer. The resulting system is more versatile and consumes less power than conventional systems.

Colorimetric sensor films comprising a reflective layer, a polymeric detection layer, and a semi-reflective layer are disclosed. Devices comprising the colorimetric sensor films and methods of making the films and devices are also disclosed.

Disclosed herein are calorimetric sensor films comprising a reflective layer, polymeric detection layer, and semi-reflective layer. Also disclosed are devices comprising the colorimetric sensor films and methods of making the films and devices.

A colorimetric reagent in the form of nanoparticles, composite nanoparticles, and nanoparticle coatings, including methods of use, methods of preparation, deposition, and assembly of related devices and specific applications. The colorimetric reagent comprises cerium oxide nanoparticles which are used in solution or immobilized on a solid support, either alone or in conjunction with oxidase enzymes, to form an active colorimetric component that reacts with an analyte to form a colored complex. The rate of color change and the intensity of the color are proportional to the amount of analyte present in the sample. Also described is the use of ceria and doped ceria nanoparticles as an oxygen storage / delivery vehicle for oxidase enzymes and applications in biocatalytic processes in anaerobic conditions of interest in biomedicine and bioanalysis. Further described are a variety of related applications of the disclosed technology including clinical diagnosis, in vivo implantable devices, food safety, and fermentation control.

An upper respiratory bacterial infection is detected from exhaled mammalian breath by using a colorimetric sensor array having a spectral response characteristic that changes when exposed to bacteria-produced analytes in the exhaled breath. A flow regulating system directs a leading portion of the exhaled breath into gaseous communication with the array to change its spectral response characteristic, and discharges a trailing portion of the exhaled breath exteriorly of the apparatus. A spectral analysis system analyzes the spectral response characteristic changed solely by the leading portion of the exhaled breath, and detects the upper respiratory bacterial infection when the bacteria-produced analytes are present therein. Reactivity of the analytes with the array is increased by advance oxidizing and / or heating the analytes.

The present invention is an apparatus and method for detecting lung cancer. The apparatus is composed of a breath capture device including a colorimetric sensor array with a plurality of chemoresponsive dyes deposited thereon in a predetermined pattern combination, wherein the dyes produce a distinct and direct spectral, transmission or reflectance response in the presence of analytes in the exhaled breath of lung cancer patients. Air flow, temperature regulation, and visual imaging components of the instant apparatus are also provided.

The invention discloses a bicolor Eu-MOFs / CDs fluorescent material as well as preparation and an application thereof. Europium ions, trimesic acid and carbon quantum dots are used as raw materials, and the bicolor fluorescent material is prepared through heat treatment in a solvent prepared by mixing N,N-dimethylformamide, distilled water and cyclohexanol. Under irradiation of ultraviolet lamps, the material can emit red fluorescence when dispersed in organic solvents and can emit blue fluorescent when dispersed in water, so that fluorescent colorimetric sensors for measuring water content in organic solvents can be prepared from the material, the prepared sensors are high in sensitivity, good in stability and low in cost and have higher population value and brighter application prospect.

An optical module (colorimetry sensor) includes an interference filter, and a transparent substrate to which a first substrate of the interference filter is fixed, having a second thermal expansion coefficient which has a value different from a first thermal expansion coefficient. The interference filter is fixed to the transparent substrate through an adhesive layer made of gel-like resin, and the adhesive layer alleviates stress generated due to a difference in the thermal expansion coefficients between the interference filter and the transparent substrate.

In some embodiments, a wound dressing that incorporates a number of sensors or sensors separate from the wound dressing can be utilized in order to monitor characteristics of a wound as it heals or to identify one or more risk factors or conditions that may precipitate a wound. In some implementations, a wound dressing configured to be positioned in contact with a wound includes a substantially flexible substrate supporting one or more sensors. The one or more sensors can include temperature sensors, conductivity sensors, multispectral optical measurements sensors, pH sensors, pressure sensors, colorimetric sensors, optical sensors, ultraviolet (UV) sensors, or infrared (IR) sensors.

Described herein is a substrate comprising at least one colorimetric component attached to a peptide, as well as methods for detecting a modification of said substrate. Also described are methods of detecting the presence or absence of a protein, for example, a protein produced by a microorganism, by contacting a substrate with a sample. If the sample contains the protein of interest, the substrate is modified and a visible color change results, indicating the presence or absence of the protein in the sample. The present invention also features biosensors and kits for detecting the presence or absence of microorganisms and / or proteins in a sample.

There is provided a polydiacetylene supramolecule comprising diacetylene molecules, capable of immobilizing a receptor molecule having a thiol group. Since the polydiacetylene supramolecule has a receptor immobilized thereon having a thiol group, for example, an antibody, and thus shows color transition when reacting with a sample, an antigen can be detected through specific color transition of the polydiacetylene when employing in a receptor-ligand reaction, for example, an antibody-antigen reaction.

A colorimetric array includes a substrate, a first spot on the substrate, and a second spot on the substrate. The first spot includes a first nanoporous pigment that includes a first nanoporous material and a first immobilized, chemoresponsive colorant. The second spot includes a second nanoporous pigment that includes a second nanoporous material and a second immobilized, chemoresponsive colorant. The first nanoporous pigment is different from the second nanoporous pigment.

Quantitative colorimetric carbon dioxide measurement and measurement systems and methods are disclosed. The methods can include methods for calibrating a chemical colorimetric indicator used in the quantitative colorimetric carbon dioxide measurement system. Apparatuses are disclosed including a cartridge comprising a chemical colorimetric indicator that is configured to removably engage with a quantitative colorimetric measurement system. Cartridges containing a sealed container comprising a reference gas with a known concentration of carbon dioxide are also disclosed. Systems and methods for humidifying the chemical colorimetric indicator are also provided. Methods for using the systems are also disclosed including providing a breathing therapy to a patient or user.

The invention discloses a mercury ion probe and its preparation method and use. The mercury ion probe can be used as a fluorescent and colorimetric sensor of a mercury ion aqueous solution, can be prepared by simple processes, and has very good selectivity and sensitivity of mercury ion detection and very fast reaction time. A test paper strip prepared from the mercury ion probe has very high sensitivity of mercury ions, a mercury ion fluorescence response detection limit of 1*10<-6> mol / L and a mercury ion colorimetric response detection limit of 1*10<-7> mol / L (20ppb). In practical application, only by naked eyes, the test paper strip prepared from the mercury ion probe has mercury ion aqueous solution detection limit of 20ppb without other apparatuses. Through convenient and cheap preparation of the test paper strip, storage convenience and actual operation convenience, the mercury ion sensor can be developed into a practical application tool for on-site examination of mercury ion pollution.

Colorimetric sensors comprising a receptor incorporated within polydiacetylene assemblies to form a transducer capable of indicating a color change when contacted with an analyte are disclosed. Methods of using the colorimetric sensor and a kit for the colorimetric detection of an analyte are also disclosed.

A colorimetric sensor includes an etalon including a first substrate, a second substrate facing the first substrate, a fixed mirror formed on a surface of the first substrate facing the second substrate, and a movable mirror formed on the second substrate so as to face the fixed mirror with a prescribed gap therebetween, a light receiving element that receives a test subject light having passed through the etalon, and a holding member holding the etalon. The etalon includes a light interference area facing the first and second substrates in a plan view as seen in a thickness direction of the substrate, and a protruding area protruding from the light interference area. The holding member holds the etalon at one end side of the protruding area opposite to the light interference area.

The invention relates to preparation and application of an aptamer colorimetric sensor for polychlorinated biphenyl 77 detection. An aptamer with a certain base sequence and specific PCB (polychlorinated biphenyl) 77 recognition capability and the colorimetric analysis technology are combined for constructing the PCB 77 aptamer colorimetric sensor. Due to adoption of the specific PCB 77 recognition aptamer as a recognition element, sensitivity and selectivity of the colorimetric sensor in PCB 77 detection are greatly improved. A PCB 77 detection linear range is 5*10<-10>-9*10<-7>mol / L, and a detection limit reaches 5*10<-11>mol / L. Compared with the prior art, the method has advantages of simplicity and convenience in operation, quickness in response, easiness in online detection and the like.

A digital still camera has a CCD image sensor, and picks up an image to produce an image signal. Colorimetric sensors have a sensor outer surface oriented in a measuring direction being different from a direction of an optical axis of the CCD image sensor, and colorimetrically measure ambient light. Lighting color temperature of the ambient light is determined according to a result of colorimetry. Image color temperature of the image is retrieved according to the image signal. A gain for each of color components is determined according to the lighting color temperature and the image color temperature. The color components of the image signal are amplified with the gain, to adjust white balance. Also, a camera body accommodates the CCD image sensor and the colorimetric sensors. The sensor outer surface is positioned on at least one of an upper surface and a lateral surface of the camera body.

A urine test for diagnosing lung cancer has been developed that uses an artificial nose such as a colorimetric sensor arrays to identify metabolic profiles in urine headspace gas. Cancer cells excrete unique compounds that are a byproduct of their metabolism. The compounds are excreted through a patient's endocrine system by filtration through the kidneys and other organs and are ultimately excreted through the urine. Some of these cancer cell by-products excrete in the urine are small volatile organic compounds (VOCs). Once the urine has exited the body, these VOCs may be outgassed to the environment. Experimental research has determined that a colorimetric sensor array as disclosed is capable of reliably identifying patients with lung cancer based after exposure to the VOCs of the urine headspace gas.

A Sorbent media exhaustion indicator produces color change when the sorbent media is saturated. The indicator's fluid inlet attach to the fluid outlet of a sorbent media device such as filter. It includes is a hollow tube or a hollow polyhedron prism that fluids flow freely through it. The indicator also includes colorimetric sensor that changes color when exposed to trace amount of toxic fluids and a trap member that prevent toxic fluids exist in the surrounding environment from changing the color of the colorimetric sensor, hence preventing false indication of sorbent media exhaustion. Another function of the trap member is to trap toxic fluids from exiting to the surrounding environment when toxic fluids breakthrough the sorbent media device.

The invention belongs to the technical field of biosensing and relates to a method of detecting an organophosphorus pesticide based on a gold nanorod and a colorimetric array. The method comprises the following steps: catalytically chloridizing acetylcholine by adopting a double enzyme system to produce hydrogen peroxide, etching the gold nanorod by the hydrogen peroxide under the action of a catalysis condition, and observing a color after reaction, wherein the double enzyme system is a system containing acetylcholinesterase and choline oxidase at the same time, and the step of etching the gold nanorod by the hydrogen peroxide under the action of the catalysis condition is a step of etching the gold nanorod by the hydrogen peroxide in an Fe<2+> containing acid solution. The method can simply, rapidly, accurately, quantitatively and visually detect the organophosphorus pesticide.

Herein are disclosed methods and devices for detecting the presence of an analyte. Such methods and devices may comprise at least one sensing element that comprises at least one optically responsive layer that comprises at least a highly analyte-responsive sublayer and a minimally analyte-responsive sublayer. Methods of making and using such sensing elements are also disclosed.

The invention discloses a CRISPR (clustered regularly interspaced short palindromic repeats) / Cas-driven DNA (deoxyribonucleic acid) hydrogel colorimetric sensor. The CRISPR / Cas-driven DNA hydrogel colorimetric sensor comprises DNA hydrogel and an sgRNA-Cas protein complex, wherein a metal organic framework material is embedded in the DNA hydrogel; the DNA hydrogel in the DNA hydrogel embedded with the metal organic framework material contains a DNA chain with a specific nucleotide sequence; and the sgRNA-Cas protein complex is formed by compounding Cas protein and sgRNA corresponding to the Cas protein, and a part of nucleotide sequence of the sgRNA is complementary with a nucleotide sequence of target DNA of a target object to be detected. According to the DNA hydrogel colorimetric sensor, the DNA hydrogel embedded with the metal organic framework material is introduced for signal amplification, a to-be-detected target does not need to be amplified or enriched, the sensitivity is high, and the accuracy is high. The invention further discloses a preparation method and application of the DNA hydrogel colorimetric sensor. The DNA hydrogel colorimetric sensor is easy to operate, short in time consumption, low in cost, high in sensitivity and accurate in detection result.

The invention relates to a colorimetric sensor for detecting mercury ions. A preparation method for the colorimetric sensor comprises the following steps: hybridization of probes; signal amplification; and colorimetric detection. The colorimetric sensor prepared in the invention realizes highly-specific detection of target mercury ions; and in virtue of nucleic acid tool enzyme, signal amplification effect is exerted.

The invention provides a visual colorimetric sensor for detecting mercury ions. An H-DNA (Hinge-Deoxyribonucleic Acid) with a special hairpin structure is designed; in the presence of the mercury ions, a 3' end and a 5' end of the H-DNA are complementary and paired through a T-Hg<2+>-T structure, so that a stem part of the H-DNA is completely complementary and exonuclease III is triggered to shearthe stem part, and then more and more single-stranded DNAs containing rich guanine are generated; released Hg<2+> also reacts with the H-DNA to trigger enzyme digestion reaction; the cycle is carriedout so that the H-DNA is continuously sheared and more and more single-stranded DNAs containing G are generated; in the presence of hematin chloride, a DNA catalyzing enzyme is formed, and 3,3',5,5'-tetramethylbenzidine is catalyzed to react with H2O2, so that a blue product is generated and the mercury ions are visibly detected. The method provided by the invention is simple to operate, low in cost and short in time, can be used for rapidly and visibly detecting the content of the mercury ions in an environment water sample and is hopefully applied to detection of mercury in the environmentwater sample.

The present invention provides, inter alia, a device comprising a colorimetric detection layer configured to undergo a color change upon interaction with a first analyte of interest. The detection layer comprises a first plurality of self-assembled fiber bundles. At least a fraction of the fiber bundles undergo a change from a first conformation to a second conformation upon interaction with the first analyte of interest, thereby undergoing a color change. The invention also provides a method for using the system to detect an analyte of interest.

The invention relates to the technical field of tea quality monitoring, in particular to a method for monitoring the fermentation degree of black tea through a hyperspectral coupled nanocrystallization colorimetric sensor. Volatile substances in the fermentation process of black tea are captured by utilizing a nanocrystallization colorimetric sensing array, colorimetric array feature information is efficiently extracted by combining a hyperspectral image technology with dimension reduction algorithms such as principal component analysis and linear discriminant analysis, and an information fusion discrimination model with strong robustness and high accuracy is established by adopting algorithms such as partial least squares discrimination, multivariate linear discrimination, a support vector machine, an extreme learning machine, an artificial neural network and a deep belief network to realize rapid and accurate discrimination of the fermentation degree of black tea. The method has the characteristics that the analysis speed is high, the sensitivity is high, the cost is low, a sample does not need to be pretreated, and online nondestructive detection is facilitated.