103results about How to "The synthetic route is simple" patented technology

A benzimidazole ester compound, 2-ethoxy-1-(p-halophenyl) methyl-1H-benzimidazole-7-carboxylate-1-[[(cyclohexoxy)carbonyl] oxy] ethylester, its preparing process, and its application in preparing medicinal compound candesartan ester are disclosed.

The invention relates to corrosion inhibitor for hydrogenation device with constituent as: 10-30% fat nitrogen-containing compound, 10-20% aromatic sulfur-containing compound, 0-25% organic acid esters, 15-70% aromatics, and 0-25% imidazoline derivative. A little this product can effective inhibiting corrosion and salt dirty without any negative effect to product property and successive process fit to high-concentration H2S-HCl-H2O acidic or H2S-HCl-NH3-H2O basic system. It can form dense monomolecular layer protection membrane on metal surface to prevent hydrogen embrittlement phenomenon and fit to heat exchanger, air cooler and others.

The invention discloses a fluorescent probe for identifying cysteine and glutathione. The structure of the probe is a chemical formula: the formula is shown in the description. The preparation methodof the fluorescent probe for identifying the cysteine and the glutathione comprises the following steps: S1, performing reaction by taking 3-carboxyl-4-chlorine-7-diethylamine coumarin and 3-hydroxyl-N-(2-ethyl morpholine)benzamide as raw materials to obtain an intermediate; and S2, performing reaction by taking the intermediate and p-nitrophenol as raw materials to obtain a probe. The fluorescentprobe can identify the cysteine and the glutathione from various kinds of amino acid and some common substances, has a lysosome targeted function at the same time, can directionally detect the cysteine and the glutathione in the lysosome, has good selectivity and high sensitivity on the cysteine and the glutathione, and has a good application prospect in detection and analysis of the cysteine andthe glutathione in environments or biological samples.

The invention discloses a carbon quantum dot sensor with copper ion and cysteine recognition functions, a preparation method and application thereof. The carbon quantum dot sensor is prepared by the following steps: taking citric acid and ethylene diamine as raw materials, adopting a microwave method to synthesize a carbon quantum dot containing carboxyl on the surface, then taking 2-bromoethylamine and 1,4,8,11-tetraazacyclotetradecane as surface functionalizing reagents, and utilizing a surface grafting technology. The carbon quantum dot sensor is good in dispersity in water, and can be used for double-selectivity fluorescence detection to the copper ion and cysteine. Compared with the existing detection technology, the carbon quantum dot sensor disclosed by the invention can detect trace of copper ion and cysteine in a pure water medium with high sensitivity and high selectivity, is simple in synthetic route, convenient to use, and suitable for large-scale synthesis and actual application in production, and has the enormous application prospect in the fields such as biology and environment detection.

The invention relates to a preparation method of flumioxazin and aims at the technical problems of high cost, low yield, not high purity, more by-products and serious pollution in an existing preparation method of flumioxazin. The preparation method disclosed by the invention comprises the following steps: 1. synthesis of 2-(5-fluoro-2-nitrobenzene oxygroup) methyl acetate; 2. synthesis of 7-fluoro-2H-1,4-benzoxazine-3(4H)-ketone; 3. synthesis of 6-nitro-7-fluoro-2H-1,4-benzoxazine-3(4H)-ketone; 4. synthesis of 6-amino-7-fluoro-2H-1,4-benzoxazine-3(4H)-ketone; 5. synthesis of 2-(7-fluoro-3-oxy-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-group)-4,5,6,7-tetralin-1H-isobenzazole-1,3(2H)-diketone; and 6. synthesis of flumioxazin. The preparation method provided by the invention is mainly applied to the preparation of herbicides.

The invention discloses a preparation method of hydrogel for drug-loaded contact lenses, which comprises the following steps: mixing polymeric monomers of hydroxyethyl methacrylate and N-vinyl pyrrolidone, an initiator, and drugs loaded by contact lenses, performing polymerization, after the reaction, swelling in water to obtain hydrogel; wherein the initiator is ammonia sulfate and tetramethyl ethylenediamine. The synthetic route provided by the invention is simple, and is strong in operability; the obtained product has performance which meets basic requirements for contact lenses, and can control the release of hydrophilic eye medicine and hydrophobic eye medicine. The invention has great social benefit and economic benefit.

The invention discloses sulfonated aromatic diamine and sulfonated polyimide resin and preparation methods thereof. The fluorine-containing aromatic diamine with a sulfonated aromatic side chain in the invention has the advantages of compact synthetic route, readily available raw materials, easy purification and higher product yield. The aromatic diamine is structurally characterized in that a sulfonic acid group is connected to the aromatic side chain, and the structure contains hydrophobic trifluoromethyl; and compared with the traditional sulfonated polyimide, the sulfonated polyimide prepared by copolymerizing the fluorine-containing aromatic diamine with the sulfonated aromatic side chain, non-sulfonated aromatic diamine and naphthalene-containing dianhydride is easier in forming micro-phase separation structures of hydrophilic and hydrophobic areas so as to endow a film with good proton conduction property. Moreover, the sulfonated polyimide provided by the invention not only has good dissolubility and film-forming property, but also shows good thermal stability and lower methanol permeability, and has important application value in a proton exchange membrane fuel cell, particularly a direct methanol fuel cell.

The invention discloses a metal organic frame fluorescent probe and application thereof in hydrogen sulfide detection. A preparation method of the metal organic frame fluorescent probe comprises the steps that 1, UiO-66-(COOH)2 containing non-coordinate carboxyl is prepared and synthesized; 2, stirring and heating are utilized, metal ions Eu3+ and Cu2+ are successfully coordinate with the non-coordinate carboxyl of UiO-66-(COOH)2, and the fluorescent probe Eu3+/Cu2+@UiO-66-(COOH)2 is obtained. The metal organic frame fluorescent probe is good in stability, and the probe can be used for rapid recognition and quantitative detection of hydrogen sulfide, and has the high selectivity and good anti-jamming capability; ratio fluorescent analysis can be achieved, influences of detection condition differences on results are greatly eliminated, and the detection sensitivity is improved. The metal organic frame fluorescent probe can be used for detecting hydrogen sulfide in environmental, biological, chemical and other samples.

The invention relates to a use of a piperazinopyrimidine isotope labeling reagent. The piperazinopyrimidine isotope labeling reagent is a light/heavy isotope labeling reagent of [d0]-/[d6]-2,4-dimethoxy-6-piperazinopyrimidine. The piperazinopyrimidine isotope labeling reagent can be used for comparison analysis of carboxyl compounds such as fatty acid, polypeptides or proteins. Fatty acid analysis comprises the following steps of a) fatty acid reacts respectively with light and heavy labeling reagents; after after-treatment, an LC-MS/MS analysis process is carried out; and product ions m/z 225 and m/z 231 are selected as quantitative ions; and b) through observation of pairs of mass spectrum peaks of the labeled fatty acid, identification of a plurality of carboxyl fatty acids is realized and quantification is realized according to relative peak areas. Polypeptide/protein comparison analysis comprises the following steps of a) a protein needing to be analyzed is subjected to thermal denaturation and enzymolysis and then reacts with the light/heavy labeling reagent; and b) the reaction solution is subjected to after-treatment; and a MALDI-TOF MS comparison analysis process is carried out.

The invention relates to a method for synthesizing organic compounds, in particular to a process method for synthesizing 4-site heteroatom-substituted cyclohexenyl halide. The method comprises the following steps of: performing refluxing reaction on 4-site heteroatom-substituted cyclohexanone (1) and 1 to 50 equivalents of anhydrous hydrazine or hydrazine hydrate in a solvent at the temperature of -20 DEG C; filtering or spin-drying the solvent to obtain corresponding hydrazone; reacting the hydrazone with a CuX2/alkali mixture in an alcohol solvent at the temperature of between -20 and 40 DEG C; adding aqueous alkali and a solvent after the reaction; performing separation to obtain mixed solution; adding organic alkali and performing the refluxing reaction; adding 1N acid to remove excessive alkali; adding saturated NaHSO3 to react; and removing the solvent to obtain the 4-site heteroatom-substituted cyclohexenyl halide (3). The method has the advantages of original and simple synthesis process and mild process condition, is easy and convenient to operate, avoids super-low temperature reaction and column chromatography purification involved in literatures, and is suitable for industrial scale-up production.

The invention discloses a method for preparing thiabendazole and relates to a method for preparing a bactericide. In order to solve the technical problems of high material cost, long synthetic route and low yield in the conventional method for preparing the thiabendazole, the method comprises the steps of 1, synthetizing 2-(alpha-ethoxy) benzimidazole; 2, synthetizing 2-acetylbenzimidazole; 3, synthetizing 2-(1,1-dichloro acetyl) benzimidazole; and 4, synthetizing thiabendazole. The method for preparing thiabendazole is low in material cost, simple in synthetic route, mild in reaction condition, short in reaction time, simple and convenient to operate, high in yield (high up to 87%) and suitable for industrial production; no catalyst is used; the solvent is recovered and reused; and the pollution to the environment is avoided. The method disclosed by the invention belongs to the field of preparation of the bactericide.

The invention discloses a synthetic process of 3, 4-ethylenedjoxythiophene. 3, 4-dibromothiophene and disodium ethylene glycol are taken as raw materials to synthesize 3, 4-ethylenedjoxythiophene in the presence of catalyst, the reaction conditions are as follows: the temperature is 50-150 DEG C, the reaction time is 5-24 hours; the catalyst is halogenated kupfer, or compound of cupric oxide and halogenated potassium. Compared with the prior art, the invention has the superiorities of short line and high yield.

The invention discloses a fluorescent probe for a specific recognition hydrazine hydrate. The molecular structural formula of the fluorescent probe is defined in the description. When the fluorescentprobe and the hydrazine hydrate act, in PBS (pH=7.4, 10 mM), fluorescence turns to be blue from green, and the hydrazine hydrate can be subjected to ratio-type detection. In addition, the fluorescentprobe can be used for hydrazine hydrate detection in the environments or cells, the selectivity to the hydrazine hydrate is good, the sensitivity is high, the anti-interference capacity is high, and the probe has a very good application prospect.

The invention discloses a diketopyrrolopyrrole and thieno[3,2-b]thiophene polymer, a preparation method of the diketopyrrolopyrrole and thieno[3,2-b]thiophene polymer and application of the diketopyrrolopyrrole and thieno[3,2-b]thiophene polymer to a field effect transistor. The diketopyrrolopyrrole and thieno[3,2-b]thiophene polymer has a structural formula as shown in the formula I, wherein R1 and R2 are respectively and independently selected from any one of C1-C120 straight-chain or branch-chain alkyls; and R3 and R4 are respectively and independently selected from any one of C1-C60 straight-chain or branch-chain alkyls. The invention also provides the preparation method of the polymer as shown in the formula I. The synthesis route is simple and efficient, raw materials are easily obtained, and the preparation method is suitable for large-scale synthesis. The field effect transistor prepared by taking the diketopyrrolopyrrole and thieno[3,2-b]thiophene polymer disclosed by the invention as an organic semiconductor layer is relatively high in migration rate and switch ratio and has the highest migration rate of 2.0cm<2>V<-1>s<-1> and the switch ratio of 105. The polymer disclosed by the invention has a favorable application prospect in organic field effect transistor devices.

The invention discloses a novel method for asymmetrically catalyzing (S)-ar-turmerone. The method comprises the following steps: by taking racemic 2-bromine propionic ester as an initial raw material, performing asymmetric Kumada cross coupling reaction under the catalysis of bioxazoline/cobalt to prepare para-toluene propionic ester, carrying out reduction and sulfonylation reaction to generate sulphonate of para-toluene propanol, subsequently carrying out cyaniding and reduction reaction to preparing para-toluene butyraldehyde, finally reacting with isocrotyl magnesium bromide, and oxidizing with PDC (Polycrystalline Diamond Compact) into the (S)-arturmerone. The method has a small amount of reaction steps, the total yield of the whole synthesis route is 31%, and the optical purity of a product is high (92%ee).

The invention discloses a naked eye visual colorimetric method-based probe {7-hydroxy-3-[(3-pyridine methylene) imine]-2H-1-benzopyran} for detecting nickel ions in an aqueous medium and a probe-based nickel ion detection kit and test paper. The nickel ion probe can be synthetized only by a three-step reaction; a detection mechanism is based on a complexing reaction; and the nickel ions in a solution can be detected by using a naked eye visual colorimetric method. The nickel ion detection kit provided by the invention comprises a reagent stock solution 1 and a reagent stock solution 2, wherein the reagent stock solution 1 is used as a buffer solution, and the reagent stock solution 2 is used as a nickel ion probe solution. The nickel ion detection test paper provided by the invention comprises the 7-hydroxy-3-[(3-pyridine methylene) imine]-2H-1-benzopyran and a solid carrier. The naked eye visual colorimetric method-based probe for detecting the nickel ions in the aqueous medium is capable of realizing the high-sensitivity and high-selectivity detection on trace nickel ions in the aqueous medium, has convenience in detection and visual judgment, and has a huge application prospect in the environmental-protection field.

The invention discloses a fluorescence probe compound, and a preparation method and an application thereof. The fluorescence probe is characterized in that the fluorescence probe is a coumarin derivative, and the structural formula of the fluorescence probe is shown in the description. The preparation method comprises the following steps: synthesizing 7-acetoxycoumarin, and then synthesizing 7-hydroxy-8-formylcoumarin; and synthesizing the fluorescence probe compound. The coumarin derivative synthesized in the invention has multiple functions, can realize the identification and the quantitative determination of Al<3+> through fluorescence spectrometry, can be used as the Al<3+> fluorescence probe, and has excellent interference resistance, high selectivity and high sensitivity in the presence of other ions.

The invention relates to a synthetic method of camphorquinone, which comprises the following steps: enabling a raw material alpha-pinene and dry chlorine hydride gas to react at -5-35 DEG C for 5-10 hours; washing the obtained reaction liquid with a 10% NaHCO3 solution, and removing the excessive HCl; drying an organic layer with anhydrous Na2SO4; steaming to remove the solvent at normal pressureto obtain a solid crude product 2-chlorocamphane; recrystallizing to obtain an intermediate 2-chlorocamphane; removing the chlorine hydride from the 2-chlorocamphane to obtain bornylene; using potassium permanganate as an oxidant, and carrying out oxidation reaction at the temperature of -15-35 DEG C for 3-24 hours; removing the byproduct MnO2 from the reaction liquid by centrifugation; after removing acetone from the solution by distillation, adding ethyl acetate for dissolving; washing with distilled water to remove the potassium permanganate; and after drying the organic layer by the anhydrous Na2SO4, steaming to remove the solvent to obtain yellow crystal camphorquinone. The invention has the advantages that the production cost of the camphorquinone is reduced, the application range ofthe camphorquinone is widened, and the production safety is improved.

The invention discloses a preparation method of bunch-shaped calcium sulphate dehydrate, belonging to the technical field of inorganic material preparation in material chemistry. The preparation method comprises the following steps of providing a calcium source by 0.1-0.5M of calcium chloride, and providing sulfate radicals by 0.05-0.25M of aluminum potassium sulfate; synthesizing in a low-concentration (0.1-0.5wt%) CMC (Carboxy Methylated Cellulose) water solution, reacting for 0.5h, washing at room temperature by taking ethanol and deionized water as leacheates, filtering, and drying at the temperature of 50-80 DEG C for 3-10h to obtain bunch-shaped calcium sulphate dehydrate. The method is low in selected raw material price, simple in synthesis route, convenient to operate and wide in application prospect.

The invention discloses a colorimetric probe compound containing carbazole-antipyrine Schiff base for detecting Cr3+ and Cu2+ as well as identifying naked eyes and preparation method thereof. The Schiff base derivative containing carbazole group is obtained by condensation reaction of aldehyde group based on carbazole and amino group in 4-amino antipyrine, and the molecular characteristic is that the Schiff base compound structure contains N-substituted antipyrine group and -C=N group and carbazole group; the probe compound comprises Schiff base derivatives containing C=N structure, simultaneously the molecule contains O and N and other coordination atoms, which can form coordination molecules with some metal ions, thereby generating special UV and fluorescence phenomenons. The compound can realize identifications of Cu2+/Cr3+ ions and quantitative determination by UV-visible spectrophotometry method, and can be used as a colorimetric probe for identifications of Cu2+/Cr3+ according to obvious color changes, moreover, with the existences of other ions, the product has the advantages of good interference resistance, high selectivity and sensitivity.

The invention discloses a preparation method of (2S,3S)-2,3-butanediol, and belongs to the technical field of biochemistry. The preparation method comprises the following steps of: stirring and mixingsolution containing ketoreductase with buffer solution to obtain mixed solution; in the stirring process, adding nicotinamide adenine dinucleotide, isopropanol and 2,3-butanedione into the mixed solution to perform closed reaction, so that reaction solution is obtained; carrying out reduced pressure suction filtration and rotary evaporation treatment on the reaction solution to obtain extractingsolution; and carrying out rectification separation on the extracting solution to obtain the (2S,3S)-2,3-butanediol. Meanwhile, the invention provides an amino acid sequence of the ketoreductase for catalyzing 2,3-butanedione to generate the (2S,3S)-2,3-butanediol. The invention further provides a nucleotide sequence for coding the ketoreductase. The preparation method is simple in synthetic routeand high in efficiency; 2,3-butanedione is reduced into (2S,3S)-2,3-butanediol by selecting the ketoreductase in an isopropanol system; the conversion rate of 2,3-butanedione can reach up to 95%; andin addition, the chiral purity of the prepared (2S,3S)-2,3-butanediol product can also reach 98%.

The invention discloses a preparation method of multi-substituted indanol derivatives. The diazo compound, alcohol and o-formyl chalcone are used as raw materials, a metal catalyst is used as a catalyst, an organic solvent is used as a solvent, and a molecular sieve is used as a water absorbent; and the multi-substituted indanol derivatives are obtained by one-step reaction. According to the preparation method disclosed by the invention, the raw materials are easily available, the operation is simple and safe, and the method is suitable for industrial production.

The invention relates to the field of functional polymer materials, especially to a fluorotriptycene tetracarboxylic dianhydride compound and a preparation method thereof, polyimide and a preparationmethod thereof. The preparation method of the fluorotriptycene tetracarboxylic dianhydride compound comprises the following steps: preparing fluorotetramethyltriptycene by using tetramethylanthraceneand fluoroanthranilic acid; then preparing fluorotriptycene tetracarboxylic acid under the action of potassium permanganate; and finally carrying out a solvothermal reaction under the condition of using acetic acid as a solvent to generate the fluorotriptycene tetracarboxylic dianhydride. The invention also provides polyimide prepared on the basis of the fluorotriptycene tetracarboxylic dianhydride. The novel polyimide polymer material prepared by using dianhydride can be widely applied to passivation of chip surface and encapsulating materials, alpha-particle shielding materials, multi-layerwiring interlayer insulating materials and photoresist materials used for drawing and through holes, and flexible printed circuit boards and other basis materials. The prepared film is almost colorless and transparent, has good heat stability, and is greatly improved in the aspects of optical and thermodynamic properties.

The invention discloses a preparation method of N epsilon-tert-butoxycarbonyl-N alpha-fluorenylmethoxycarbonyl-N epsilon-methyl-lysine. The preparation method comprises the following steps: taking N alpha-fluorenylmethoxycarbonyl-lysine hydrochloride as a raw material, performing alkylation with halide (R-X) under alkaline conditions, performing reductive amination on alkylate in an aqueous formaldehyde solution to introduce methyl, removing an R group of a reductive amination product under acidic conditions, then introducing a t-butyloxycarboryl (BOC) protecting group under alkaline conditions and performing re-crystallization treatment to obtain a product. The preparation method disclosed by the invention is simple in synthetic route and mild in reaction conditions, and the next-step reaction can be directly carried out after an intermediate is simply washed and concentrated. The reaction yield in each step is close to quantification, the total yield can reach above 80 percent, the purity of a final product exceeds 98 percent, and a safe and efficient synthetic route is provided for the preparation of the N epsilon-tert-butoxycarbonyl-N alpha-fluorenylmethoxycarbonyl-N epsilon-methyl-lysine.

The invention discloses a new hole transport material taking tetrathienopyrrole as a core and methoxyl substituted triphenylamine as a peripheral modifying group and a preparation method and application thereof, and belongs to the field of application of perovskite solar cells. The new hole transport material is simple in synthetic route and easily available in raw materials, and has relatively high photo-thermal stability and hole migration efficiency. The new hole transport material is applied to perovskite solar cells, results show that the highest photoelectric conversion efficiency of 16.62% can be obtained, and the new hole transport material has a relatively good application prospect.

The invention discloses a sulfonic acid group-containing attapulgite corrosion and scale inhibitor and a preparation method as well as application thereof, and belongs to the technical field of water treatment. The preparation method of the sulfonic acid group-containing attapulgite corrosion and scale inhibitor comprises the following steps of: dissolving attapulgite in water; raising temperature; dropwise adding saturated aqueous solution of sodium p-styrene sulfonate and maleic anhydride into an attapulgite water system; dropwise adding ammonium persulfate aqueous solution serving as an initiator in 10-15 minutes; and stirring at a constant temperature and then performing evaporative crystallization to prepare the sulfonic acid group-containing attapulgite corrosion and scale inhibitor. The environment-friendly scale inhibitor synthesized by the invention has the advantages of wide raw material source, good water solubility, no secondary pollution caused to water, good tolerance to Ca<2+>, excellent scale inhibition effect on calcium carbonate and good ferric oxide dispersion effect. The preparation method has the advantages of cheap, simple and readily available raw materials, simple synthetic line and low reaction condition requirements; and the synthesized scale inhibitor has the advantages of good water solubility, good calcium carbonate scale inhibition and good ferric oxide dispersion performance.

The invention discloses a [2,1-b:3,4-b'] 2,2'-bithienyl-naphthalene diimide-containing conjugated polymer, which is characterized by being a compound shown as a general formula in the specifications, wherein R1 and R2 refer to alkyl with 1-20 carbon atoms; R3 refers to alkyl with 1-20 carbon atoms or shown substituted phenyl; R4, R5 and R6 represent hydrogen and alkyl or alkoxyl with 1-20 carbon atoms likewise or differently; x is more than or equal to 1 and less than 2; y is more than 0 and less than or equal to 1; x+y=2; and an is an integer ranging from 1 to 120. The [2,1-b:3,4-b'] 2,2'-bithienyl-naphthalene diimide-containing conjugated polymer is prepared by undergoing a Stille reaction which has a simple reaction synthesis route and low process requirements, and has high film forming performance, high thermal stability performance, high carrier mobility, high molar absorptivity, a wide light absorbing range and wide application; and the matching degree with a sunlight emission spectrum is increased, and the photoelectric conversion efficiency can be increased.

The invention relates to a high-activity jateorhizine platinum (II) complex and a synthesis method thereof as well as an application of the complex in preparing anti-cancer drugs. The synthesis methodincludes: 1), dissolving brominated jateorhizine derivatives, potassium chloride and dimethyl arsenic amine into a solvent for reaction at 90DEG C to obtain yellow solid powder which is a Jat ligand;2), dissolving the Jat ligand prepared in the step 1) and dichlorodium (dimethyl sulfoxide platinum) (II) in an acetonitrile solution for complexation reaction at 55-65DEG C; 3), washing and drying the product to obtain the target product. In the synthesis method, the novel jateorhizine derivative Jat is firstly taken as the active ligand to be synthesized the platinum complex, superior antitumoractivity and targeting in vitro and in vivo are shown, potential medicinal value is achieved, and the jateorhizine derivative Jat is expected to be used in the preparation of various antitumor drugs.The structural formula of the high-activity jateorhizine platinum (II) is shown as follows.

The invention relates to the technical field of preparation of silica gel chromatography materials, and discloses a method for preparing chromatographic stationary phase by using divinyl sulphone as a template. The method comprises the following steps: firstly, synthesizing a chemical reagent with divinyl sulphone silane, bonding the chemical reagent with the surface of a matrix, and performing nucleophilic addition with a reagent with sulfydryl, amino and hydroxyl. The method for preparing the chromatographic stationary phase, which is disclosed by the invention, is simple, rapid, gentle in condition, low in cost and high in bonding quantity. Due to adoption of divinyl sulphone, reactive chemical properties of electrons can be easily obtained from an external environment, the surface of silica gel can be modified, and an affine reagent comprises easily added sulfydryl, amino and hydroxyl at one end and amino acid containing C18, glycosyl, carboxyl, amino or zwitter ions simultaneously at the other end, and functional aglucon of biomacromolecules such as protein. The method for preparing a silica gel chromatographic material is concise in step, gentle in condition and high in aglucon bonding efficiency, a diversity of chromatographic materials can be prepared, and can be applied to high performance liquid chromatography separation.

The invention discloses a preparation method of a metal complex fluorescence probe for detecting hydrogen sulfide. A dansyl chloride derivative has large stokes shift and relative high quantum yield,a synthetic route is simple, and the probe has good light stability; the probe contains a polydentate ligand, and by coordinating with copper ions, the stable dansyl chloride copper metal complex probe is generated. The copper complex probe has good sensitivity analysis on hydrogen sulfide, and has good selectivity on hydrogen sulfide.