121 results about "Naphthalic anhydride" patented technology

Fluorescent monomers are described and claimed which are synthesized by reacting a substituted or non-substituted naphthalic anhydride with an amine and with a moiety containing a polymerizable group. Such monomers are useful for the preparation of tagged treatment polymers. Such tagged treatment polymers are useful as scale inhibitors in industrial water systems.

Disclosed is a herbicidal mixture comprising (a) at least one herbicide compound selected from the pyrimidines of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof:whereinR1 is cyclopropyl, 4-Br-phenyl or 4-Cl-phenyl;X is Cl or Br;R2 is H, C1-C14 alkyl, C2-C14 alkoxyalkyl, C3-C14 alkoxyalkoxyalkyl, C2-C14 hydroxyalkyl or benzyl; and(b) at least one additional herbicide or herbicide safener compound selected from the group consisting of (b1) ACCase inhibitors, (b2) AHAS inhibitors, (b3) photosystem II inhibitors, (b4) photosystem I electron diverters, (b5) PPO inhibitors, (b6) EPSP synthase inhibitors, (b7) GS inhibitors, (b8) VLCFA inhibitors, (b9) auxin mimics, (b10) auxin transport inhibitors, (b11) other herbicides selected from the group consisting of flamprop-M-methyl, flamprop-M-isopropyl, difenzoquat, DSMA, MSMA, bromobutide, flurenol, cinmethylin, cumyluron, dazomet, dymron, methyldymron, etobenzanid, fosamine-ammonium, isoxaflutole, asulam, clomazone, mesotrione, metam, oxaziclomefone, oleic acid, pelargonic acid and pyributicarb, (b12) herbicide safeners selected from the group consisting of benoxacor, 1-bromo-4-[(chloromethyl)sulfonyl]benzene, cloquintocet-mexyl, cyometrinil, dichlormid, 2-(dichloromethyl)-2-methyl-1,3-dioxolane, fenchlorazole-ethyl, fenclorim, flurazole, fluxofenim, furilazole, isoxadifen-ethyl, mefenpyr-diethyl, methoxyphenone, naphthalic anhydride and oxabetrinil, and their salts. Also disclosed is a method for controlling the growth of undesired vegetation comprising contacting the vegetation or its environment with a herbicidally effective amount of a mixture of the invention (e.g., as a composition described herein).

Fluorescent monomers are described and claimed which are synthesized by reacting a substituted or non-substituted naphthalic anhydride with an amine and with a moiety containing a polymerizable group. Such monomers are useful for the preparation of tagged treatment polymers. Such tagged treatment polymers are useful as scale inhibitors in industrial water systems.

The invention belongs to the field of biological analysis and detection and relates to fluorescent probes for labelling and / or detecting lipid droplets in cells as well as preparation and applicationsof the fluorescent probes. The probes are synthesized with 4-bromo-1,8-naphthalic anhydride as an initial material and take 1,8-naphthalimide as a fluorophore, a C12 alkyl long chain as a specific lipid droplet positioning group and an N-containing group on the 4th site of a naphthalene ring as a fluorescence enhanced and stabilized group. The probes are simple to prepare and have high yield. Compared with existing Nile red and boron dipyrromethene lipid droplet fluorescent probes, the probes have high light stability and large stokes shift and are more suitable for fluorescence imaging. Theprobes have very important application value in cell labelling fluorescent imaging and biomedical fields.

The invention provides a fluorescent monomer and a fluorescent acrylic acid polymer and a preparation method of the fluorescent monomer and the fluorescent acrylic acid polymer. The monomer and polymer are respectively shown in formulas (I) and (2), wherein m is 1 or 2, n is 10-120, R1 is H or -CH3, R2 is -CH3, -CH2CH3,-CH2CH2CH3 or -CH2CH2(OH)CH3. The preparation method is as follows: reacting 4-bromine-1,8-naphthalic anhydride with n-propylamine so as to obtain N-propyl-4-bromine-1,8-naphthalimide; reacting the N-propyl-4-bromine-1,8-naphthalimide with ethanolamine so as to obtain N-propyl-4-(2-ethoxyamino)-1,8-naphthalimide; reacting the N-propyl-4-(2-ethoxyamino)-1,8-naphthalimide with PBr3 so as to obtain N-propyl-4-(2-bromomethylamino)-1,8-naphthalimide, and dropwise adding unsaturated compound dimethylaminoethyl methacrylate so that the fluorescent monomer is obtained; and condensing the fluorescent monomer with at least one crylic acid monomer. The fluorescent polymer can be used as a special scale inhibitor for a sea water circulating cooling or sea water desalinization system, and has a good scale dispersion property and a good fluorescent trace characteristic.

The present invention discloses water treating agent containing methoxy naphthalene as fluorescent marker. The water treating agent is prepared through the first reaction of 4-chloro-1, 8-naphthalic anhydride, glacial acetic acid and 3-dimethylamino propylamine to obtain 4-chloro-N-3-dimethylamino propyl-naphthyl imide; the subsequent reaction with sodium methoxide to introduce methoxy group and obtain 4, 4-methoxyl-N-3-dimethylamino propyl-naphthyl imide, which is reacted with allyl chloride to obtain quaternary ammonium salt of 4-methoxyl-N-3-dimethylamino propyl-naphthyl imide allyl chloride as fluorescent monomer with fluorescent characteristic and double bond; and the final polymerization with phosphorus containing compound, acrylic acid and other monomer to obtain the multifunctional water treating agent with corrosion retarding, scale inhibiting, dispersing and fluorescent tracing functions.

Fluorescent monomers are described and claimed which are synthesized by reacting a substituted or non-substituted naphthalic anhydride with an amine and with a moiety containing a polymerizable group. Such monomers are useful for the preparation of tagged treatment polymers. Such tagged treatment polymers are useful as scale inhibitors in industrial water systems.

A phosphino-based mapropyl copolymer containing fluorescent group and its production are disclosed. The process is carried out by taking 4-bromine-1,8-naphthalic anhydride, glacial acetic acid and N, N-dimethyl-ethylenediamine as raw materials to obtain 4-bromine-N-(2-N,, N,-dimethylbenzidine-ethyl)naphthalimide, reacting it with sodium methoxide to induce methoxy-group to obtain 4-methoxy-N-(2-N,, N,- dimethylbenzidine-ethyl)naphthalimide, reacting it with allyl chloride to obtain fluorescent monomer 4-methoxy-N-(2-N,, N,- dimethylbenzidine-ethyl)naphthalimide allyl ammonia chloride with fluorescent characteristic and double-bond, polymerizing it with sub-sodium phosphate, maleic anhydride, acroleic acid and propenyl-sodium sulfate to obtain the final product. It has fluorescent tracting, corrosion-inhibting, scale-inhibiting and dispersion functions.

Herbicidal injury caused by 6-(trisubstituted phenyl)-4-amino-2-pyridinecarboxylates in wheat and barley is reduced with the use of AD67 (MON 4660), benoxacor, 2-CBSU, daimuron, dichlormid, dicyclonon (BAS 145 138H), fenchlorazole-ethyl, fenclorim, fluxofenim, furilazole (MON 13900), glyphosate, isoxadifen-ethyl, mefenpyr-diethyl, naphthalic anhydride, oxabetrinil and mixtures thereof.

The invention discloses a naphthalimide derivative and an application thereof; the naphthalimide derivative contains three 1,8-naphthalimide fluorophores; 4-bromo-1,8-naphthalic anhydride is dispersed in absolute ethyl alcohol, and then tri(2-aminoethyl)amine is dropped into the mixture to obtain white powder after treatment; the obtained white powder and N,N-Dimethylethylenediamine are mixed to dissolve according to a mole ratio of 1: (160-298); and the naphthalimide derivative can be obtained after the reaction for 24-72 hours at the temperature of 75-95 DEG C. The naphthalimide derivative disclosed by the invention can be used as a pH iuminophor switch, and the action of the switch is not influenced by various co-existing ions.

The invention discloses a ratiometric fluorescent probe for detection of hydrogen sulfide and a preparation method of the ratiometric fluorescent probe. A compound of the probe is 2-(6-azido-1,3-dioxo-benzoisoquinolinyl)ethyl 2-(4-((4-(1,2,2-triphenylvinyl)phenoxy)methyl)-1,2,3-triazolyl)ethyl)succinate. During the preparation, 4-bromo-1,8-naphthalic anhydride is reacted with 2-aminoethanol to obtain a solid, namely, 6-bromo-2-(2-hydroxyethyl)-benzoisoquinoline-dione, the product is reacted with sodium azide to obtain a solid, namely, 6-azido-2-(2-hydroxyethyl)-benzoisoquinoline-dione; and then 6-azido-2-(2-hydroxyethyl)-benzoisoquinoline-dione is subjected to a series of reaction to obtain the solid probe compound. The probe compound is composed of hydrophobic tetraphenylvinyl and hydrophilic receptor units containing azide group and can be used for quantitative analysis of hydrogen sulfide in chemical, biological, environmental and other samples.

The invention belongs to the technical field of analysis and detection, and discloses a fluorescence probe for detecting beta-galactosidase as well as a preparation method and application of the fluorescence probe. The substrate of the fluorescence probe is 2-(2-(dimethylamino)ethyl-6-(((3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxidation)-1H-benzisoquinoline diketone, and has a structural formula shown in the description. The fluorescence probe has the advantages that naphthalic anhydride is taken as a fluorophore of the substrate of the fluorescence probe, and lined with a galactose group which can respond to the specificity of beta-galactosidase; the ratio of double fluorescence signals being I554 / I445 is taken as a detection signal, and thus the detection accuracy is higher; under the condition of 1U / L enzyme concentration, obvious fluorescence alteration can be detected, and the lower detection limit is 0.35 U / L; the fluorescence probe is excited (418 nm) in a visible light region, so that the background interference can be eliminated to achieve a better detection effect.

The invention discloses a probe molecule based on a 1,8-naphthalimide derivative, a preparation method and an application. The schiff base modified 4-naphthalimide derivative is prepared as the probemolecule by allowing 4-bromine-1,8-naphthalic anhydride and ethanolamine to give a condensation reaction to form 4-bromine-N-2-aminoethyl alcohol-1,8-naphthalimide to react with hydrazine hydrate to form 4-hydrazino-N-2-aminoethyl alcohol-1,8-naphthalimide and allowing pyrrole-2-methanal and primary amine of 4-hydrazino-N-2-aminoethyl alcohol-1,8-naphthalimide to give a condensation reaction; andthe probe molecule takes a pyrrole heterocyclic ring as a receptor and naphthalimide as fluorescent chromophore and achieves specific identification and concentration response of Cu<2+> via changes inabsorbance, fluorescence and a color. The probe molecule has the advantages of simple synthesis method, low cost, easiness and simplicity in operation, good selectivity, high sensitivity, low detection limit and the like, and can be used for real-time and quick detection of a complicated sample.

The invention discloses a 1,8-naphthalimide derivative as well as a synthesis method and an application thereof. The derivative is N-(3,4-methylene dioxophenethyl)-4-(3-N,N-dimethylamino)propylamino-1,8-naphthalimide; and the compound is prepared by taking 4-bromo-1,8-naphthalic anhydride as a raw material which sequentially reacts with 3,4-methylene dioxophenylethylamine and N,N-dimethyl-1,3-diaminopropane. The synthesis method is simple and easy to control. The applicant observes the proliferation inhibition activity of the 1,8-naphthalimide derivative on 9 human tumor cell strains and two normal cell strains, and the results indicate that the in-vitro antitumor activity is remarkable and the 1,8-naphthalimide derivative has relatively good potential medicinal value and is expected to be applied to the preparation of various anti-tumor drugs. The chemical structural formula of the compound disclosed by the invention is shown by the formula (I).

The invention discloses a heterocyclic-fused naphthalimide and a preparation method and application thereof. The preparation method of the compound provided by the invention comprises the following steps: 1) 4-bromine-1, 8-naphthalic anhydride and an N-R1 compound are reacted in a solvent A to obtain a compound B; and 2) the compound B obtained in step 1), 1, 2, 4-triazole and K2CO3 are reacted in a solvent B, and the reaction liquid is collected to obtain the compound disclosed in formula (I). An experiment in the invention proves that the compound prepared in the method disclosed by the invention can be used as a naphthalimide fluorescent probe used for monitoring pH, can be used for sensitively monitoring the subtle change of the pH under a physiological condition in a water solution with the pH of 5.5-7.5, and has a narrow range of response.

The invention relates to a small-molecule fluorescent probe used for ratio recognition of human carbonic anhydrase, and a synthetic method and application thereof. The probe is prepared by reacting 4-amino-1,8-naphthalic anhydride with chloroacetyl chloride, diethylamine, 4-aminomethylbenzenesulfonamide and like. The synthetic method is simple to operate and uses cheap raw materials. The probe emits blue fluorescent light with a wavelength of ~470 nm in an aqueous solution and emits green to yellow fluorescent light with a wavelength of 525 to 560 nm in polar solvents like methanol, dimethyl sulfoxide, N,N-dimethyl formamide and ethanol. In a 20-mM phosphoric acid buffer, when human carbonic anhydrase 1 with an equivalent of 0 to 0.7 is gradually added, a fluorescence peak at a wavelength of ~470 nm gradually attenuates and a fluorescence peak at a wavelength of ~530 nm gradually intensifies. Thus, the probe provided by the invention can realize ratio recognition of human carbonic anhydrase and eliminates influence of external factors like equipment and samples.

The invention provides a fluorescent probe for detecting pH in endoplasmic reticulum of a cell. The formula is as shown in the description. The probe is prepared by carrying out three-step reactions by taking 4-bromo-1,8-naphthalic anhydride, BOC-ethanediamine, trifluoroacetic acid and paratoluensulfonyl chloride. The fluorescent probe can be used for detecting pH in a solution or the endoplasmicreticulum of the cell. The fluorescent probe can be obtained through chemical synthesis. The synthetic process is simple and feasible, the raw materials are cheap, the preparation cost is low, and theprobe is easy to popularize, high in specificity, is not affected by other components, has a two-photon property, can be used for detecting the pH in the endoplasmic reticulum of a living cell in a tissue and has a wide application prospect.

The invention provides a two-photon fluorescent probe for detecting hypochlorous acid in a cellular endoplasmic reticulum. The two-photon fluorescent probe can be obtained through a three-step reaction by using 4-methylthio-1,8-naphthalic anhydride, trifluoroacetic acid and p-toluenesulfonyl chloride as raw materials. The two-photon fluorescent probe can be applied to detection of the hypochlorousacid in a solution or the cellular endoplasmic reticulum. The fluorescent probe can be obtained through chemical synthesis, a synthesis technology is simple and easy to implement, the raw materials are cheap and easy to obtain, the preparation cost is low, and the fluorescent probe is easy to popularize, has high specificity, is not interfered by other components, can be applied to real-time determination of the hypochlorous acid in the endoplasmic reticulum of a living cell and has a broad application prospect.

The invention discloses a fluorescence probe for hydrogen sulfide detection and a preparation method thereof. The preparation method comprises the following steps: firstly, enabling fuming sulfuric acid to react with 4-amino-1,8-naphthalic anhydride, and enabling an obtained product to be subjected to reflux with cetylamine in a turbid liquid manner in ethyl alcohol as a solvent which hardly dissolves the obtained product, wherein the obtained product is still a turbid liquid; collecting and dissolving solid in water, enabling the solid to react with sodium nitrite in ice-batch, enabling solid, which is separated out, to suspend in methanol, dropwise adding the methanol solution of sodium azide at about a low temperature of 40 DEG C, reacting for hours at the low temperature to obtain 3-(sodium) sulfonate-5-nitrine-1,8-naphthalimide. The probe has a property of being able to carrying out target marking on a cytomembrane surface and characteristic solubility, can enable the probe to be only embedded in cytomembrane instead of striding over the cytomembrane to enter a cell, and can be used for detecting endogenous H2S. The probe per se has relatively weak fluorescence, can selectively react with the H2S in a physiological condition to generate a derivative with relatively strong fluorescence, and is not interfered by a living organism, common matter in the environment and a biological medium background.

The invention belongs to the polyetherimide preparation technical field and particularly relates to a naphthalene-containing polyetherimide polymer prepared from a new dihalogen monomer containing naphthalene ring and a preparation method thereof. The preparation method comprises the following steps: dissolving 4-halogeno-1,8-naphthalic anhydride and diamine in DMAc, entraining water in the present of water-carrying agent, then dewatering at high temperature to obtain the dihalogen monomer containing imide structure; then adopting the monomer and sodium salt of bisphenol as reactants and tetramethylene sulfone (TMS) as solvent to perform high emperature polymerization in the present of xylene carrying water and synthesizing a new polyetherimide containing naphthalene structure. The invention synthesizes the new polyetherimide containing naphthalene structure which has higher glass-transition temperature and six-membered imide ring containing naphthalene ring structure is introduced so as to increase the hydrolysis resistance of polyetherimide material to a certain degree. The polymerization method avoids to prepare the polyetherimide of the invention through the synthesis of ether-containing dianhydride and adopts sulfolane as solvent for polymerization which can be recycled so as to lower the production cost.

Herbicidal injury caused by 6-(trisubstituted phenyl)-4-amino-2-pyridinecarboxylates in wheat and barley is reduced with the use of AD67 (MON 4660), benoxacor, 2-CBSU, daimuron, dichlormid, dicyclonon (BAS 145 138H), fenchlorazole-ethyl, fenclorim, fluxofenim, furilazole (MON 13900), glyphosate, isoxadifen-ethyl, mefenpyr-diethyl, naphthalic anhydride, oxabetrinil and mixtures thereof.

The invention belongs to a fluorescent chemical sensor in a one-dimension nano structure and especially relates to a preparation method of sulfur ion fluorescent chemical sensor based on silicon nanowire or silicon nanowire array. Surfaces of the silicon nanowire or the silicon nanowire array are covalently modified successively by 3-[2-(2-aminoethylamino)ethylamino]propyl-trimethoxy silane and 4-amino-1,8-naphthalic anhydride. An obtained silicon nanowire, or silicon nanowire array, of which the surfaces are modified by 4-amino-1,8-naphthalic dimethylamide fluorescent groups is further reacted with copper ion to form a complex for obtaining the sulfur ion fluorescent chemical sensor based on the silicon nanowire or the silicon nanowire array. The sulfur ion fluorescent chemical sensor based on the silicon nanowire or the silicon nanowire array can be used in detection of sulfur ion in a solution system containing the sulfur ion and has a wide application prospect in detection of the sulfur ion in a water body in real time and in situ.

The invention belongs to the field of fluorescent probes in analytical chemistry and relates to a ratiometric fluorescent probe compound for detecting hypobromous acid and application thereof. The synthetic method comprises the following steps: reacting 3-amino-4-bromo-1,8-naphthalic anhydride and 4-(2-amino ethyl) morpholine to produce an intermediate product II, and carrying out a coupled reaction between the compound II and 2-methylthiophenylboronic acid, thereby obtaining the probe molecule. The probe is excellent in stability and simple in preparation method, response on the hypobromous acid has the advantages of being ratiometric, high in selectivity, rapid and sensitive, and other activated small molecules, ions and amino acids do not produce interference to detection of the hypobromous acid. The probe provides a novel method for detecting the hypobromous acid, and has excellent application prospects.

The invention relates to a ratiometric fluorescent probe for detecting avidin, and a synthesis method and an application thereof. The probe is obtained by carrying out a reaction of an intermediate 4-(2-N,N-diethylamino)acetyl)amino-1,8-naphthalic anhydride with biotin and the like, and the synthesis method has the advantages of simple operation and cheap raw material. The probe has two fluorescence peaks at 470 nm and 550 nm appearing at different ratios of water and methanol. A 20 mM phosphoric acid buffer solution has a fluorescence main peak at 470 nm; when 0-2.0 equivalent of avidin is added to the buffer solution, the fluorescence peak at 470 nm is weakened gradually while the fluorescence peak at 550 nm is gradually enhanced, so as to achieve the ratio detection of avidin.

The invention discloses a water-soluble copper ion fluorescent probe and a preparation method thereof and belongs to the technical field of chemical synthesis and analytical chemistry. The chemical name of the water-soluble copper ion fluorescent probe disclosed by the invention is N-n-butyl-4-[ethylenediamine-2-N,N'-di(3-propionic acid)]-1,8-naphthalimide; a synthesis method of the water-soluble copper ion fluorescent probe comprises the following steps: firstly, carrying out amidation on 4-bromo-1,8-naphthalic anhydride and n-butylamine; replacing 4-site bromine with ethylenediamine; then carrying out Michael reaction on a product of the last step and methyl acrylate; finally, carrying out alkaline hydrolysis and treating through a cation exchange column to obtain the copper ion fluorescent probe. An experiment shows that the probe can be used for selectively detecting copper ions and has fluorescent quenching in a DMSO / HEPES (Dimethyl Sulfoxide / 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) buffering system; the copper ions are quantitatively detected; the water-soluble copper ion fluorescent probe has high detection sensitivity and the identification is not interfered by other ions, so that the copper ion fluorescent probe can be used for detecting heavy metal ions and is especially used for detecting the copper ions in biological tissues and environment sewage.

The invention designs and synthesizes host-guest assembled supramolecular gel based on the functionalization of trimesoyl chloride. N-amino-1, 8-naphthalic anhydride functionalized trimesoyl chlorideas a main body and 4-amino pyridine-functionalized trimesoyl chloride as a guest are complex and assembled into the gel in a H2O-DMSO system. The supramolecular gel has good fluorescence emission properties and emits yellow-green fluorescence when the excitation wavelength is 380nm. A series of aqueous cationic solutions are added to the supramolecular gel, and only Fe<3+> can quench the fluorescence of the supramolecular gel. In the metal gel TG-Fe formed by coordination of the supramolecular gel and Fe<3+>, a series of anions are added respectively. Only H2PO4<-> can restore the fluorescenceof the metal gel TG-Fe. This competitive coordination recognition property has an important application value in the field of ion identification.

The invention discloses application of a fluorescent tracer type itaconic acid and aspartic acid copolymer in preparation of a water treatment agent. A preparation method of the fluorescent tracer type itaconic acid and aspartic acid copolymer comprises the steps of using 4-bromine-1,8-naphthalic anhydride, ethanol and N, N-dimethyl 1, 3-propane diamine as raw materials to obtain 4-bromine-N-(3-N', N'-dimethyl aminopropyl)-1, 8-naphthalimide first; and then using ethanol and ethylene glycol methyl ether as a mixed solvent to react with n-butylamine so as to obtain a product; enabling the product to react with allyl chloride to obtain 4-butylamino-N-(3-N', N'-dimethyl aminopropyl) naphthalimide diallyl ammonium chloride; and using a water-phase one-step synthesis method to copolymerize a fluorescent monomer FT, itaconic acid and aspartic acid to obtain a product. The application of the fluorescent tracer type itaconic acid and aspartic acid copolymer in the preparation of the water treatment agent, disclosed by the invention, has the advantages that a target has multiple functions such as a fluorescent tracer function and a scale inhibition and dispersion function, the formed scaleis easy to be flushed away by water, and better dispersion performance is shown.

The invention discloses a preparation method for a reaction type fluorine ion molecular probe. The preparation method is characterized in that a novel fluorine ion molecular probe based on benzimidazobenzisoquinolinone-12-silyl ether is prepared from 1,8-naphthalic anhydride, 2, 3-diaminophenol and tert-butyldiphenylsilane as raw materials. The molecular probe has the advantages of simple and convenient synthesis, mild reaction condition, easy purification, stable optical performance and the like. Oxygen-silicon bonds (R-O-Si) in the molecular probe can be broken through a specific reaction of probe molecules and fluorine ions in a DMSO medium, so that the probe molecules are transformed into negative oxygen ions (R-O-); the maximum absorption wavelength is subjected to red shift (225nm), so that the yellow color is changed to the blue color; the naked eyes can clearly distinguish the color change; and the absorption intensity and the fluorine ion concentration have a good linear relationship. High selectivity for the fluorine ions is expressed, the interference of other negative ions is avoided, and the response speed is high. The probe modules have important practical application values in the fields of biomedical chemistry, environmental science and the like.

The invention discloses tris [4-(4-morpholine)-1, 8-naphthalimide ethyl] amine fluorescent reagent and preparation and application thereof, and belongs to the technical field of organic synthesis and analytical chemistry. Tris-amino ethyl amine is used as a structure platform to react with 4-(4-morpholine)-1, 8-naphthalic acid anhydride to obtain the compound a with a chemical name of tris [4-(4-morpholine)-1, 8-naphthalimide ethyl] amine, and three side chains of the compound are connected with fluorophores. Reaction raw materials are easily obtained, the synthesis method is simple, and the target product can be obtained by the two steps of reaction. In N, N-dimethyl formamide / water (V / V, 3 / 2), tris (hydroxymethyl) aminomethane-hydrochloric acid (Tris-HCl, pH6) buffer solution mixed solvent, the compound a can be used as a fluorescent or colorimetric reagent for detection of trace Al <3 + > and Cr <3 + >. The structure formula of the compound a is as shown in the specification.