279 results about "Nano dispersion" patented technology

Compositions are provided comprising a lipophilic active compound, e.g., a human or veterinary drug or a nutraceutical, interwoven with a polymeric matrix formed by two or more polymers, wherein one of the polymers is an amphiphilic polymer and the other polymer is either an amphiphilic polymer with a different hydrophobic-hydrophilic balance or a hydrophilic polymer, and the active lipophilic compound has modified physicochemical properties. The composition forms colloidal nanodispersion upon contact with aqueous media.

A novel cyclosporine formulation, which is a pro-nanodispersion at room temperature, featuring solid particles of a relatively large particle size (at least about 150 nm) and yet which is a nanodispersion at body temperature.

The invention discloses a nano reinforcing method for recycled aggregate concrete, which belongs to the technical fields of recycling comprehensive utilization of waste and production of building materials, and is mainly characterized by comprising the steps of: mixing and stirring a recycled aggregate and a nano particle dispersion for 5-10s; after the surface of the recycled aggregate is in a moist state, further mixing the recycled aggregate with all admixtures for 5-10s; and mixing and stirring with cement, water and a high-efficiency water reducing agent for 20-45s to obtain a nano-reinforced recycled aggregate concrete mixture. The nano reinforcing method has a principle that by changing a stirring process and introducing the nano dispersion, nano particles can be adsorbed into the opening pores and microcracks of the recycled aggregate, an admixture enriched layer is further formed on the surface of the recycled aggregate, the nano particles permeating into the interiors of the opening pores of the recycled aggregate and the admixture enriched layer formed on the surface of the recycled aggregate are used for jointly absorbing calcium hydroxide enriched on the surface and the pores of the recycled aggregate in the strength development process of the recycled aggregate concrete, a gelling material with higher strength is generated through hydration, liquid-phase or solid-phase reactions so as to reinforce the recycled aggregate per se and an interface between the recycled aggregate and set cement, and thus, the strength of the recycled aggregate concrete is enhanced. After the nano reinforcement, the recycled aggregate concrete has the 28-day compression strength improved by around 15-20%.

A composite material which may be used as an electrode for a battery or other electrochemical device, or as a catalyst, has a matrix which is one or more metal carbide, metal nitride, metal boride, metal silicide or intermetallic compound. A metallic component is dispersed in the matrix. The metallic component comprises a metal and an agent which increases the melting point of the metal. The metallic component may be nanodispersed in the matrix. A specific material comprises a nanodispersion of tin, alloyed with an element which increases its melting point to at least 600° C., disposed in a matrix of a transition metal carbide or nitride. This material has very good utility as an anode material for lithium batteries. Also disclosed are other compositions as well as methods for manufacturing the compositions.

A single step milling and surface coating process allows for production of a stable dispersion of surface coated nanoparticles in an efficient manner. The process comprises providing feed particles, providing a coating agent, and generating the stable dispersion of surface coated nanoparticles by milling the feed particles in an aqueous medium containing the coating agent such that the coating agent bonds to surfaces of the feed particles as the feed particles are milled to an average particle size of less than about 100 nm.

The instant invention relates to a solid product comprising a liquid biologically active agent which is intimately associated to a stabilizing agent; particularly a solid product that can be reconstituted to a clear, stable, stabilized nanodispersion or loaded micelles comprising a polymer as a stabilizing agent and a liquid, preferably water immiscible, biologically active agent. The instant invention is further directed toward a process for the production of the above solid product; particularly to micelles or nanodispersions produced by hydration of a cake or powder of the solid product, produced via an effective treatment of a stabilized solution comprising for example a polymer as a stabilizing agent, such as an amphiphilic block copolymer or a small molecular weight surfactant, loaded with a liquid biologically active agent, such as propofol, an optional additive, and a suitable solvent.

Delivery of a substance to a subterranean location is achieved by suspending the substance as nanoparticles in a carrier fluid in which the substance is insoluble. The procedure may start by forming a dispersible powder composition, which is done by dissolving the substance in a solvent, emulsifying the resulting solution as the dispersed phase of an emulsion, and freeze-drying the emulsion to a powder. On mixing the powder with a fluid in which the substance is insoluble, any soluble constituents of the powder dissolve and the insoluble substance becomes a dispersion of nanoparticles of the substance. Then, the fluid containing the dispersed substance is pumped to the subterranean location. The dispersion of nanoparticles has surprising stability, facilitating transport to the subterranean location. At the subterranean location the dispersed nanoparticles may migrate into other fluid encountered there: more specifically a dispersed tracer substance may migrate from injected water into hydrocarbon in a hydrocarbon reservoir. Another possibility is that dispersion as nanoparticles enables interaction with other constituents of the fluid to be delayed until the subterranean location is reached: more specifically the fluid may contain polymer and the dispersed nanoparticles may comprise an agent which participates in cross-linking and consequent viscosification of the polymer.

The invention discloses a fluorosilicone rubber nano-composite alloy triplicate-prevention paint and the production method. The organic silicon provided with hydroxyl is introduced into the carbon resin, and is dispersed into resin polymerize and cross-linked by a variety of polymer resin via nano-particle which is processed by nano-dispersion solution; and then the fluorosilicone rubber nano-composite alloy triplicate-prevention paint which can resist salt spray, acid, alkali and impact; has strong adhesive attraction, strong resistance to elements, and heavy corrosion resistance; can prevent pollution flashover , and can drain for anti-icing is produced by modifying the obtained resin. The invention has high reaction energy and ultra-low surface energy, can resist chemical corrosion and electrochemical corrosion, has ability for resisting strong corrosion medium, has strong adhesive attraction and high reliability between paint film layers, can prevent water, oxygen and other corrosion mediums from destructing, can resist ultraviolet radiation, can resist temperature change, has super resistance to elements, has long coating maintenance usage duration, and is applicable to bad weather conditions and all kinds of strong corrosive environments.

The invention discloses a method for preparing a nano-carbon coated lithium battery anode material. An active carbon material which is highly graphitized and has a porous structure is prepared from waste crops, and serves as a substrate; uniformly dispersed nano tin dioxide particles are loaded on the substrate subjected to simple treatment, natural or synthetic polymer is used as a carbon source, and a carbon layer coats the nano tin dioxide particles so as to fulfill the aim of combining the regulation function of nano dispersion of the nano particles on volume expansion of the tin dioxide with the restraint and buffer function of the coated carbon layer on the tin dioxide particles; therefore, higher battery capacity and cycle stability can be achieved.

Disclosed herein are formulations suitable for parenteral administration of certain hydrophobic active agents such as Coenzyme Q10. Methods of preparing the same and methods of treatment of oncological disorders using the same are also provided herein. The formulations comprise an aqueous solution; a hydrophobic active agent dispersed to form a colloidal nano-dispersion of particles; and at least one of a dispersion stabilizing agent and an opsonization reducer wherein the colloidal nano-dispersion of the active agent is dispersed into nano-dispersion particles having a mean size of less than 200-nm. Methods of preparing the parenteral formulations comprise dispersing the hydrophobic active agent by high pressure homogenization by (1) adding hydrophobic active agent to a 65° C. bath of water and mixing to form a hydrophobic active agent / water mixture; (2) adding a dispersion stabilizing agent to the hydrophobic active agent / water mixture and mix at 65° C. to form a hydrophobic active agent / water / stabilizer mixture; (3) adding an opsonization reducer to form a hydrophobic active agent / water / stabilizer / reducer mixture; (4) pre-heating a Microfluidizer to 65° C.; and (5) processing by mixing the hydrophobic active agent / water / stabilizer / reducer mixture in the Microfluidizer at 65° C. such that a hydrophobic active agent colloidal nano-dispersion having a mean particle size less than 200-nm is formed. Provided herein are also methods of treating oncological disorders by administering formulations described herein to a subject such that treatment or prevention of the oncological disorder occurs.

The invention discloses a cross-linked polyethylene power cable nano repairing liquid and repairing method thereof, which is characterized in that inorganic nano particles and organic solvent form nano dispersion, and a layer of inorganic nano protective film is formed by filing air gaps or micropores inside the cable through the inorganic nano particles based on a siloxane repairing liquid so as to protect a polyethylene insulating layer. Compared with the traditional siloxane repairing technology, the invention can prolong the residual service life of the power cable by 5-10 times, has the advantages of advanced technology, safety and stability, short repairing time and good repairing effect.

The invention provides a method for producing high-dispersing multi-group amphiphilic nano silicon oxide powder or dispersion, which comprises: firstly, refining sodium silicate serving as a raw material by adding hydrogen peroxide; adding a surfactant in the refined sodium silicate serving as the raw material, controlling the formation and growth of particles by segmental acid addition precipitation; and at the same time, performing in-situ modification by replacing hydroxyl on the surfaces of the silicon dioxide particles with organic groups. In the process, the temperature and the pH valueare controlled first, and then the high-dispersing silicon dioxide powder is prepared by filtration, washing, vacuum filtration and drying. And the dispersing time is controlled by a combined dispersing technology of mechanical dispersion, grinding and ultrasound waves and by adding a combined dispersant and a stabilizer to further disperse in situ modified powder to prepare a nano dispersion. Thedispersion is stable in performance and good in dispersion effect and keeps the dispersion state of nano particles.

The invention discloses water-based environment-friendly porcelain glaze-like plastic coating and a preparation method thereof. The water-based environment-friendly porcelain glaze-like plastic coating adopts a formula comprising the following materials by mass: 20 to 40 percent of a water-based acrylic emulsion, 10 to 20 percent of water-based silica sol, 35 to 50 percent of water-based inorganic silicon dioxide nanodispersion, 0.1 to 0.3 percent of a wetting dispersant, 1 to 5 percent of silane, 0.1 to 0.5 percent of an amine neutralizing agent, 5 to 10 percent of lead-free pigment, 0.5 to 2.5 percent of a film-forming additive, and 5 to 25 percent of deionized water. The water-based environment-friendly porcelain glaze-like plastic coating can be coated on the surfaces of various materials in the form of porcelain glaze, and can be applied on the surfaces of the materials of various shapes through roller-applied coating, shower coating, spraying, blade coating, brush coating, dip coating and the like; moreover, the formed porcelain glaze coating is unique and free from hydrolysis, and cannot be melted at a certain temperature, so that a base material can be effectively protected from corrosion, abrasion, scraping, acid-alkali, impact, inflaming and fire.

The invention relates to resveratrol nanoscale dispersoid and a preparation method thereof. The resveratrol nanoscale dispersoid comprises: by mass, 1 to 20% of resveratrol as an active component, 40 to 80% of auxiliary materials and 5 to 40% of additives. The resveratrol nanoscale dispersoid is dispersed in cold water thereby forming a transparent solution, wherein resveratrol particle sizes are less than 150 nanometers. The preparation method comprises the following steps of dissolving resveratrol in a water-soluble organic solvent to obtain a resveratrol solution, dissolving certain amounts of the auxiliary materials and the additives in water to obtain an aqueous solution containing the auxiliary materials and the additives, adding the resveratrol solution into the aqueous solution containing the auxiliary materials and the additives to obtain a transparent mixed solution, and carrying out spray drying of the transparent mixed solution to obtain the resveratrol nanoscale dispersoid. The preparation method of the resveratrol nanoscale dispersoid having high stability and good water dispersibility can be used in the fields of drugs, health products, foods and cosmetics.

The invention relates to a medicinal transparent nano dispersant and a preparation method thereof. Water-insoluble medicinal nano particles are used as active ingredients, water is used as a dispersion medium, medicinal accessories are used as a colloidal dispersion system of a stabilizing agent, the concentration of the medicament is 0.1 to 10mg / mL, the mass ratio of the stabilizing agent to the medicament is (10-500): 100, and the average particle diameter of the medicinal particles is 20 to 90 nanometers. The method comprises the following steps of: dissolving the medicament into an organic solvent mutually soluble with water, adding the medicament solution into aqueous solution containing water-soluble medicinal accessories to obtain nano medicinal paste, performing spray drying on suspension, and adding the obtained nano and micro structure composite powder into the water to obtain the medicinal transparent nano dispersant. The method provided by the invention is simple in operation and low in cost, and has good industrialized production prospect; and the provided medicinal transparent nano dispersant has the advantages of good stability, high dissolution speed, high bioavailability and the like, and can be used for preparing soft capsules, injection and suspension.

The invention discloses a Chinese herbal medicine nanometer silver-loaded titanium dioxide air cleaning agent and a preparation method thereof. The Chinese herbal medicine nanometer silver-loaded titanium dioxide air cleaning agent comprises a component A and a component B, wherein the component A comprises the sub-component of: an effective active ingredient formed by carrying out alcohol extraction and water extraction on drying powder of eight Chinese herbal medicines, and the component B comprises the sub-component of: nanometer silver-loaded titanium dioxide dispersion colloid; and the component A and the component B are highly dispersed and emulsified, adsorbed and assembled to form stable nanometer dispersoids. The Chinese herbal medicine nanometer silver-loaded titanium dioxide air cleaning agent is a multi-component complex with sterilization, anti-virus and mildproof functions so that the superposition and synergism effect of the Chinese herbal medicine nanometer silver-loaded titanium dioxide air cleaning agent is greatly enhanced; the Chinese herbal medicine nanometer silver-loaded titanium dioxide air cleaning agent has fairly strong capability of adsorbing and catching harmful substances such as influenza viruses and bacteria carried secretly during breathing and sneezing of people and livestock, particles and dust; the influenza viruses can be immediately killed when being in contact with Chinese herbal medicines active substances and nanometer silver-loaded materials; and the Chinese herbal medicine nanometer silver-loaded titanium dioxide air cleaning agent has a very remarkable indoor and outdoor air purification effect and is an ideal, green, safe and effective anti-influenza virus air cleaning agent.

The invention provides a preparation method for a reflection-deducting coating, the method comprises the following steps of: (1) preparing nano dispersion agent: SiO2 and / or Al2O3 nano particles are / is dispersed into a solvent to form the nano dispersion agent; and (2) preparing the coating: the nano dispersion agent is coated on a substrate to form the coating by curing. The method has the following advantages that the method is simple and feasible; a large area of film shaping on the coating can be realized; a remarkable attachment between the coating and the substrate can be realized; the method can be applied in wide substrate materials; and the prepared coating has the effects of effectively decreasing reflection and increasing transmission, and the performance of light transmission of the substrate is greatly increased by utilizing a double-face coating.

The invention discloses a special master batch for a PC (Polycarbonate) sunlight board and application thereof. The preparation method of the special master batch for PC sunlight board comprises the following steps of: (1) carrying out nano dispersion and modification to dispersing agent, the ATO (Arsenic Trioxide) content of which accounts for 0.1%-10% of the mass of the ATO to obtain ATO nanoparticles, wherein the dispersing agent is a silane coupling agent or stearic acid, and the ATO is stibium-doped stannic oxide; and (2) fusing and mixing the ATO nanoparticles in PC resins to prepare the special master batch for PC sunlight board, wherein the mass fraction of the ATO is 1%-50%. The master batch has high processing fluidity and is suitable for preparing the PC sunlight board with higher transparence and good heat-insulation effect.

The invention relates to preparation method of rubber / halloysite nanotube nano-composite material, the invention adopts the preparation method that the rubber, the halloysite nanotube and modifying agent are mixed according to the mass ratio of 100:5 to 100 : 0.5-20 through the ordinary rubber pugging equipment and technique, then the sulphation is performed through the ordinary sulphidizing process and equipment to realize the in-situ modification, and finally, the rubber / halloysite nanotube nano-composite material with nano-dispersion, good interfacial bonding and good performance. Wherein, the modifying agent comprises compound in-situ generated phenolic resin, alkyl phenolic resin, modified rubber, methacrylic acid metal salt and one or more than one mixture (s) in the sulfur-containing organosilane coupling agent. The preparation method of rubber / halloysite nanotube nano-composite material has the advantages that the defects that the rubber / halloysite nanotube nano-composite material is difficult to be dispersed, the interfacial bonding is not good, the performance can not be improved observably can be overcome, and the preparation method can be applied in a variety of rubber products, rubber toughening plastics and binding agents and the like.

The invention relates to a method to prepare a new hydrophilic coating for outside wall containing nmself-crosslinking acrylic ester latices and nm inorganic powder. Its dispensation is:nm indoor crosslinking acrylic ester latex(5-40%), indoor crosslinking acrylic ester latex(20-50%),inorganic nm powder(0.1-20%),inorganic filler(10-50%),film-forming assistant(0.05-5.0%) and the other is water without ion. Its preparing method is:firstly use high speed dispersion and sand grinding method to prepare nm disperseion and filler color which are then mixed with nm self-crosslinking acrylic ester latex and general acrylic ester latex, add into assistant and stir them by media-low speed for 0.5-1.5h,filter and package. The coating has good stability and film-forming performance,strong adhesive force and resistance to pollution, outstanding thermo insulating property, as well as self-cleaning performance.

The invention relates to a nanometer heat-insulating glass film and a manufacturing method thereof. The components of the film comprise a nano high polymer latex, nano powder dispersion liquid and assistants, and the manufacturing method comprises the following steps: selecting the nano high polymer latex; adopting ultrasonic dispersion and grinding technology to make nano powder into nano dispersion liquid; and then adding proper assistants to compound the nano high polymer latex and the nano dispersion liquid. The components of the film all have water solubility, and the aqueous one-component technology reduces the cost of the product. The film has the characteristics of environment-friendly and safe production and simple and easy-to-use construction, and has the property same as an oily product.

The invention discloses a heat-resistant polyimide / polyhedral oligomeric silsesquioxane nanometer hybrid material. The glass transition temperature of the heat-resistant polyimide can be adjusted by changing the content of polyhedral oligomeric silsesquioxane. The invention also discloses a method for preparing the heat-resistant polyimide / polyhedral oligomeric silsesquioxane nanometer hybrid material, and obtains an organic / inorganic hybrid material with nano-dispersion. The heat-resistant polyimide has excellent thermal properties, widens the application of polyimide-type materials in the aspects of aerospace, aviation, high-temperature resistant coatings, high-temperature resistant heat-insulation foaming materials, high-temperature structural adhesive and the like, and endows the polyimide-type materials with broad application prospects.

The invention provides a preparation method of a water-dispersive ternary mixed-crystal nano titanium dioxide photocatalyst. The preparation method comprises the following steps of: adding a titanium precursor into an absolute alcohol solvent at a room temperature, and uniformly stirring to obtain a titanium precursor alcoholic solution; then adding an acid hydrolysis inhibitor into the obtained titanium precursor alcoholic solution, and uniformly stirring the acid hydrolysis inhibitor and the obtained titanium precursor alcoholic solution, thereby obtaining a mixed solution; adding alcohol aqueous solution into the obtained mixed solution, uniformly stirring the alcohol aqueous solution and the obtained mixed solution, and standing for 1-20 minutes, thereby obtaining a gel; performing solvent thermal reaction on the gel at a temperature of 140-200 DEG C for 2-24 hours, then naturally cooling the reactant mixture to room temperature, and performing centrifugalizing, washing, vacuum drying and grinding, thereby obtaining a target product. Due to adoption of synthesis process based on a one-pot method, the preparation method is high in productivity, low in energy consumption and free from pollution; the product can form a nano dispersion in water and has quite high catalytic activity on organic sewage under a condition of visible lights.

The invention provides a process method for preparing high-performance carbon black masterbatch, relating to the technical field of carbon black masterbatch preparation processes. The wet-method carbon black masterbatch preparation process method provided by the invention is simple in process, low in energy consumption and excellent in performance. The method comprises the steps: soaking non-granulated carbon black powder in an aqueous solution of a micromolecular volatile solvent, so as to prepare uniformly-dispersed carbon black slurry; flocculating out masterbatch and carbon black at a certain stirring linear speed without adding other flocculating agents, filtrating and drying. The carbon black in the masterbatch prepared by the method disclosed by the invention reaches nano dispersion, vulcanized rubber has the advantages of excellent mechanical property, good resilience, low heat generation and high wear resistance, the preparation process is simple, the equipment investment is small, the energy consumption is low, the cost is low, the method is environmental-friendly, and the influence on the performance of the rubber and the pollution to the environment, caused by a surfactant, a flocculating agent and the like, are avoided.

The invention relates to a modification method of nano magnesium hydroxide, which comprises the following steps: nano magnesium hydroxide powder is added into deionized water to be prepared into slurry; the slurry is added into a container which is arranged in an ultrasonic trough and provided with a stirrer to be stirred and receives ultrasonic dispersing activation treatment; and then surface modifier is added in to continue the ultrasonic stirring modification; the modified magnesium hydroxide receives suction filtration and is washed, heated, dried, ground and screened to obtain surface modified magnesium hydroxide powder. The method really realizes the nano dispersion of nano particles in the solution and modifies the surface of the nano particles with the help of the multiple functions of ultrasonic cavitation to the dispersion and surface activation of the nano particles as well as the accelerated hydrolysis, accelerated polymerization and polycondensation reaction of the modifier. The surface modification is carried out at normal temperature, so that the process is simplified, the time is short, the efficiency is high and the energy consumption is greatly reduced; the prepared modified nano magnesium hydroxide powder has good dispersivity, and the size and distribution of the particles are even.

This invention relates to thermosetting inorganic clay nanodispersions comprising an inorganic clay treated in situ with an intercalation agent and a non-aqueous, chemically reactive, organic intercalation facilitating agent, wherein the amount of intercalation facilitating agent is sufficient to facilitate intercalation and to disperse said inorganic clay. The thermosetting inorganic clay nanodispersions comprise an inorganic clay dispersed in an intercalating agent and an intercalation facilitating agent. Thermosetting inorganic clay nanodispersions are used to prepare thermosetting nanocomposite articles.

The present invention relates to a nanodispersion composition comprising sirolimus and a surface modifier wherein effective average particle size of Sirolimus is more than 400 nm and process for preparation thereof.