832results about How to "Improve retention" patented technology

A firing system for an applicator instrument adapted to dispense surgical fasteners includes a housing, an elongated shaft extending from the housing, a firing rod disposed within the elongated shaft, a firing rod release engageable with the firing rod for preventing distal movement of the firing rod during at least one stage of a firing cycle, a trigger mounted to the housing, and a firing spring having a first end connected with the firing rod and a second end adapted for being sequentially coupled and decoupled from the trigger during the firing cycle. The firing cycle includes an initial stage in which the trigger is open and decoupled from the energy storing element, and the firing spring is at least partially compressed, and a piloting stage during which the firing rod release is disengaged from the firing rod for enabling distal movement of the firing rod.

Elastomeric compositions comprising graphite nanoparticles (preferably graphene nanoparticles) and methods for making same. Such compositions are useful for tire innertubes and tire innerliners.

Compositions and methods are provided that include a biologically active agent and a permeabilizing agent effective to enhance mucosal delivery of the biologically active agent in a mammalian subject, in which the permeabilizing peptide is PN159, PN159 analogues, conjugates of PN159, conjugates of PN159 analogues, or complexes thereof. The permeabilizing agent reversibly enhances mucosal epithelial paracellular transport, typically by modulating epithelial junctional structure and/or physiology at a mucosal epithelial surface in the subject.

An injection-molded thermoplastic closure with shake-and-spoon apertures and associated flaps for selectively closing and opening the apertures. The flaps are releasably retained in their closed positions by catch elements which provide retention forces that are relatively insensitive to dimensional and shape variations in the body resulting from the molding process. In one embodiment, the cap has "freeze points" and a gate location that reduce the tendency of the cap to assume an oval condition when cooled from molding temperatures. A wide sealing ledge cooperates with a central support for a liner seal positioned in the cap to seal the mouth of a container.

Compositions containing at least one silicone resin film former and at least one copolymer comprising at least one backbone and at least one chain, wherein at least one of the at least one backbone and at least one chain is chosen from silicones.

The invention provides a polymer porous membrane, a preparation method of the polymer porous membrane, a polymer electrolyte, a polymer battery and a preparation method of the polymer battery. A carbon material is dispersed in the polymer porous membrane, so that the degree of crystallization of a polymer which constitutes the polymer porous membrane is lowered and the liquid absorption of the polymer porous membrane is increased; the liquid absorption rate, liquid holding capability and ionic conductivity of the polymer porous membrane are increased; interface impedance is reduced, battery magnification discharging performance and the circulating performance of the battery are enhanced; simultaneously, the battery prepared by the method has excellent high temperature circulation and storage performance and low expansion ratio at a high temperature and further meets the development requirement of the polymer battery. Simultaneously, the preparation method is simple and is easy to implement and the prepared battery has high performance.

The capability of retaining a resistance value of a stored state and an erased state is improved in a resistance variation-type memory device. A memory layer 5 including a high-resistance layer 2 and an ion source layer 3 is provided between a lower electrode 1 and an upper electrode 4. The ion source layer 3 contains Al (aluminum) as an additive element together with an ion conductive material such as S (sulfur), Se (selenium), and Te (tellurium) (chalcogenide element) and a metal element to be ionized such as Zr (zirconium). Since Al is included in the ion source layer 3, the high-resistance layer which includes Al (Al oxide) is formed on an anode in erasing operation. Thus, a retaining property in a high-resistance state improves, and at the same time, an operating speed is improved.

A humerus implant has a stem, cup shaped body and a locking adapter. The cup shaped body is locked to the stem by a key-slot mechanism. The cup shaped body has a center portion and a plurality of flexible first sidewall segments and second sidewall segments, with gaps between neighbored sidewall segments. The first sidewall segments have a plurality of locking fins while the second sidewall segments having a plurality of recesses and holes. The locking adapter has means for fixing the locking adapter to the cup shaped body and a locking ring for locking the sidewall segments into their final positions.

An ear bud earphone having an outer portion, which may be a microphone or sound input or a contact for wires or acoustic tubes, a central body portion, an ear canal main body and a tab. The ear canal main body of the earphone has flexibility to conform to the ear anatomy. The ear (pinna) has a helix, an anti-helix, a concha including the anatomical elements of a cymba and a cavum, and an ear canal. The ear canal main body is partially inserted into the concha and ear canal opening, with the tab resting on or under the anti-helix.

The invention relates to a preparation method of a star polycarboxylic acid high-performance water reducing agent. Polybasic alcohol and (methyl) acrylic acid used as main raw materials for esterification are esterified and polymerized to prepare the star polycarboxylic acid high-performance water reducing agent material: the (methyl) acrylic acid and polybasic alcohol used as reactants are esterified under the action of a catalyst to firstly prepare a star polymerizable active terminal, and free-radical polymerization reaction is carried out with unsaturated polyethenoxy ether, molecular weight regulator and unsaturated carboxylic acid monomer under the action of an initiator to prepare the star polycarboxylic acid high-performance water reducing agent. The invention is easy to control, and has the advantages of high polymerization degree, low cost and no pollution; the esterification reaction is carried out form an active core, and the free-radical polymerization is carried out to generate the chain arm, thereby implementing the polycarboxylic acid high-performance water reducing agent in a star molecular structure; and under the condition of common doping amount and low doping amount, the star polycarboxylic acid high-performance water reducing agent has better cement paste flowability and holding capacity than the traditional linear and comb polycarboxylic acid water reducing agents, and has favorable cement adaptability and concrete application performance.

The present invention is directed to delivery and retention of active agents to targeted lymph nodes in a mammal using a ligand/anti-ligand pair. More particularly, the invention involves methods, compositions, and kits for delivery and retention of active agents to targeted lymph nodes using compositions comprising a ligand-colloid moiety and compositions comprising an anti-ligand. Active agents may be associated with one or more of the colloid, ligand, or anti-ligand. Conjugation of the ligand and anti-ligand after administration permits retention of aggregated colloid complex in targeted lymph nodes.

Methods of making superabrasive tools having improved retention of superabrasive particles in a metal matrix are provided. Such methods may include providing a substrate, providing superabrasive particles, chemically bonding the superabrasive particles with the metal matrix to a degree which holds the superabrasive particles in the metal matrix without substantially degrading the superabrasive particles, and metallurgically bonding the superabrasive particles to the substrate with the metal matrix.

The present invention relates to targeted delivery systems for delivering therapeutic agents to tumor. The invention further relates to methods of delivering a therapeutic agent to a tumor for the prevention and treatment of cancer by killing tumor cells and tumor-associated endothelial cells. In particular, the present invention provides a tumor-targeted drug delivery system comprising a NGR-containing molecule linked to a delivery vehicle encapsulating a therapeutic agent, preferably a drug, such as a cytotoxic agent or a chemotherapeutic agent. Specifically, the delivery systems of the present invention are capable of delivering an increased amount of therapeutic agent to a tumor as compared to other delivery systems. In particular, the delivery systems of the present invention are capable of accumulating a higher amount of therapeutic agent in a tumor, or in the vicinity of a tumor cell or tumor-supporting cell, resulting in exposure of the tumor cell and tumor-associated endothelial cell to therapeutic levels of the agent for a longer period of time as compared to other delivery systems. The present invention also describes pharmaceutical compositions comprising the delivery systems of the present invention. The present invention further relates to a tumor treatment comprising an increased amount of therapeutic agent delivered by the system of the present invention as compared to other delivery systems. The delivery systems and pharmaceutical compositions can be administered to a subject, preferably a human, alone or in combination, sequentially or simultaneously, with other prophylactic or therapeutic agents and/or anti-cancer treatments.

The present invention provides silica-based reversed-phase HPLC methods that lead to higher retention of the analytes in the column and longer column lifetimes than usually observed under medium to high pH aqueous mobile phase conditions. The inventive methods comprise eluting the HPLC column using an aqueous mobile phase comprising at least one fluorinated additive. Preferred additives are polyfluorinated alcohols such as 2,2,2-trifluoroethanol and 1,1,1,3,3,3-hexafluoroisopropanol. The methods of the present invention may be used for analyzing, separating, purifying, and/or isolating small organic molecules, natural products, as well as biomolecules such as polypeptides, oligonucleotides and polynucleotides (e.g., DNA fragments).

The present invention relates to releasable fusogenic lipids and nanoparticle compositions containing the same for the delivery of oligonucleotides and methods of modulating gene expression using the same. In particular, this invention relates to releasable fusogenic lipids containing an imine linker and a zwitterionic moiety.

The present invention discloses a system and method for ensuring service level in content dispensing network (CDN).Said system is set in CDN, which includes service level protocol (SLA) unit and global system load balancer (GSLB); wherein said SLA unit used for configuring and saving SLA between user and CDN service provider to realize mapping between service quality indices and network performance indices; GSLB used for accessing user service request, according to current CDN network performance status, select CDN route and node fitting said SLA service quality indices mapped network performance indices requirement as current user request to provide service. The present invention can insure user required service level and raise CDN network service quality of management.

The invention discloses a method for improving the calcium carbonate retention rate through adding calcium carbonate before pulp beating. The method includes the steps that tobacco powder, tobacco stem and fragmentary tobacco pieces are immersed in water to obtain mixed slurry, and the mixed slurry is extracted and separated to obtain soluble tobacco fiber and non soluble tobacco fiber; mixed beating is conducted to the non soluble tobacco fiber and calcium carbonate to obtain slurry material, outer fiber and chitosan are added to the obtained slurry material to obtain slurry material before pulping after being evenly mixed, and the slurry material before pulping is manufactured into a substrate in a pulped mode; evaporation and concentration, and fragrance adding and tinting are conducted on the obtained soluble tobacco fiber to obtain coating liquid with relative density ranging from 1.102 to 1.325; the coating liquid is sprayed on the substrate, and finally after drying and slicing up are conducted, the reconstituted tobacco is obtained. The method for improving the calcium carbonate retention rate through adding the calcium carbonate before pulp beating is simple and practical, the prepared reconstituted tobacco is better in coating rate and calcium carbonate retention rate than the reconstituted tobacco prepared through an existing technology, the quality of the reconstituted tobacco is not influenced, and popularization and application in actual production are facilitated.

The invention relates to a method for increasing the retention rate of calcium carbonate in paper-process reconstituted tobacco sheets. The purpose of the invention is to solve the problems that: since the prior art directly adds calcium carbonate, the bonding force between the calcium carbonate and tobacco fibers is weak, as a result, loss is severe, the material utilization rate is low, the amount of waste water to be treated is large, and the treatment cost is high. The technical point is that: needed chemical constituents are extracted from tobacco material, residue is ground into pulp after extraction, and the concentration of the pulp is regulated between 3 percent and 25 percent; the solution of soluble carbonate accounting for 4 percent to 40 percent of the weight of dry fibers in the pulp is added into the pulp, and is fully stirred and uniformly mixed, and impregnation is then carried out for 20 to 150 minutes, so that the fibers of the pulp can be impregnated with the soluble carbonate; the solution of soluble calcium salt, the molar mass of which is approximately equal to the molar mass of the soluble carbonate, is added into the impregnated pulp, and is fully stirred and uniformly mixed, static reaction is then carried out for 30 to 180 minutes, and the reaction temperature is controlled at 5 DEG C to 50 DEG C; and after the static reaction, the pulp is made into reconstituted tobacco sheets by papermaking equipment.

A rotary hammer and a power tool. The rotary hammer is operable in an idle mode and a hammer mode and comprises a housing and a barrel positioned in the housing and having a forward portion. A ram is positioned within the barrel and is movable relative to the barrel between hammering positions and an idle position. In some aspects, a ram catcher assembly is positioned along the axis adjacent the forward portion of the barrel to releasably hold the ram in the idle position. The ram catcher assembly includes a friction member frictionally engageable with the ram and a damping member at least partially surrounding the friction member. As the ram moves to the idle position with a force, the damping member absorbs at least a portion of the force and the member applies friction to the ram.

An electrical operating panel, in particular for height-adjustable tables equipped with actuators or lifting columns driven by an electric motor. The panel has a first part (1) intended for fixed mounting of the panel and a second part (2) with operating keys (19) for activating electrical switches. The two parts are hinged together, and the hinge is formed with a rotary shaft (10) on the no part and a bearing with a cylindrical face (13) on the other part and formed with interengaging projections (16) and depressions (15) such that the second part may assume various angular positions relative to the first part, the force between projections and depressions bearing greater than the necessary operative pressure on the operating keys, but smaller than the force necessary to manually move the second part between the various angular positions. The panel is of simple structure and easy to mount and use. The users may easily set the keyboard part in the desired angular position. Furthermore, the panel yields so that it is not damaged in case of collision with an object.

The invention provides salt coating liquid. The salt coating liquid is made with, by weight, 0.5-10% of calcium acetate and 90-99.5% of tobacco sheet coating liquid. After treated by a high-temperature process, the calcium acetate in the salt coating liquid is partially decomposed into calcium carbonate which can convert on the surface of the reconstituted tobacco into a great amount of calcium carbonate particles, so that retention rate and distribution uniformity of the calcium carbonate in the reconstituted tobacco can be significantly improved, specific area is greatly increased, a novel microporous structure is generated, water absorbing and moisture preserving performances of the structure are effectively improved, whiteness and flame retention rate of ash from combustion of the reconstituted tobacco can be improved, bulkiness of the reconstituted tobacco is improved, and thickens of the reconstituted tobacco is increased; in terms of smell absorption, tobacco miscellaneous odors can be decreased, irritation is lowered and comfort is improved. In addition, the undecomposed calcium carbonate is hydratable calcium salt with very high hygroscopic property; good moisture preserving effect and certain mould resistance are provided.

The invention discloses a food wrapping paper and a production method thereof. Poplar chemical mechanical pulp, bleached kraft softwood pulp and bleached kraft hardwood pulp are used as fiber raw materials. Sizing, desanding and degassing, sizing, fine sieving, wire dehydration forming, pressing, pre-drying, surface sizing, post-drying, calendering, coiling, and packaging to form food packaging paper. The present invention uses the surface sizing treatment method to process the product, and adds a starch surface sizing agent to the surface sizing to improve water resistance and adds a small amount of sizing agent alkyl ketene dimer to the surface sizing glue, which can Improve the retention rate, save costs, and make products more cost-effective.

The invention relates to a preparation method of paraffin wax / AKD complex type neutral paper-making sizing agent. The step is as follows: firstly, AKD and paraffin wax powder are melted in AKD solution; secondly, compound emulsifying agent after being heated is added in melted AKD solution and mixed with a quick shearing mixing machine; thirdly, a rotating speed of the quick shearing blending machine is improved and preheating water is added to lead the formed AKD solution to performing emulsification nearby a W/O to O/W inversion point; quick mixing is performed and the preheating water is added and the mixing is continuously performed; fourthly, the water solution of flocculating agent PAC is added, and the mixing is continuously performed; fifthly, the mixing is stopped and the cold water is used for quickly performing cooling and cool down, and then the finished product of the paraffin wax / AKD complex-typed neutral paper-making sizing agent emulsion is produced. The complex-typed neutral sizing agent produced by the invention has the advantages that the holding rate is high, the effect on the physical property of the paper is small, and the emulsion is stable.

A fastening device is provided for fastening cables, fibers or wave hoses in position with multiple ways, and for waterproof capability. The fastening device includes a first casing, an inner holding part, a waterproof screw annulus, a positioning nut, a connecting casing, a second casing, an inner buckled nut, a resilient washer, and a constricting gasket. The first casing and the second casing are respectively engaged with the waterproof screw annulus and the connecting annulus. The first casing and the second casing take force to the wave hose for holding the cable or fiber in place in multiple ways, and avoid shifting or breaking off from drawing outside. The fastening device also has multi-ways for waterproof.

The invention discloses an electrode pole plate of a lithium ion battery. The electrode pole plate comprises a current collector and active substance coating layers, wherein the active substance coating layers are uniformly coated at two sides of the current collector, and grooves are symmetrically and uniformly formed in surfaces of the active substance coating layers at two sides. A thick pole plate with specially-shaped grooves in a surface are prepared, the electrolyte retention quantity in the battery can be remarkably increased, and long-term recycle of the battery is promoted; moreover, the specially-shaped grooves are uniformly formed in the surface of the thick pole plate, electrolyte penetration and diffusion are facilitated, and the rate charge-discharge electrochemical performance of the battery is improved; and meanwhile, the specially-shaped grooves are uniformly formed in the surface of the thick pole plate, thus, the specific area of the pole plate is expanded, the polarization current density of the battery during the charge-discharge process is reduced, a lithium precipitation risk of a large-current charging positive electrode separator is improved, and the application safety of the battery is improved.

The invention discloses a method for coating and modifying surface of inorganic paper making fiber calcium sulfate whisker, which comprises the following steps: 1) mixing the calcium sulfate whisker with a dispersant relative to 1-10% of mass fraction of calcium sulfate whisker, dispersing the calcium sulfate whisker; filtering and drying after treating to obtain the calcium sulfate whisker with high dispersion; 2) measuring water, ethanol, ammoniacal liquor and organosilicon source with set volume ratio, placing the water, ethanol and ammoniacal liquor in a three-mouth flask, performing magnetic stirring, adding a proper amount of surfactant, uniformly mixing for standby; 3) adding the prepared calcium sulfate whisker with high dispersion in the three-mouth flask filled with a mixed solution, uniformly mixing, slowly adding the measured organosilicon source by batches; and 4) stirring and modifying the prepared mixed solution at the temperature of below than 25 DEG C, subsiding for 8-10 hours, filtering, and drying under the temperature of 95% to prepare the modified calcium sulfate whisker.

The invention regards an ear canal device and a retainer strip, whereby the ear canal device has a distal part for extending into the ear canal and facing the tympanic membrane and a proximal part extending towards the ear canal opening, wherein the proximal part of the ear canal device comprises an opening extending transversely through the ear canal device, and where a retaining strip is arranged with a first end thereof arranged to be fastened in the opening and a second end arranged to lie resiliently against the inside of the concha for exerting a retaining force on the ear canal device.

A stopper member 54 is fixed to an inner column 3a, and a second displacement preventing protruding portion 57 provided in the stopper member 54 is opposed to a bolt 42 fixed to an outer column 2b. In the case where a load not less than a predetermined value is given from the bolt 42 to the second displacement preventing protruding portion 57, the second displacement preventing protruding portion 57 is deformed and the thus deformed portion is withdrawn into an accommodating recess portion 60 provided in the stopper member 54. A plate spring made of conductive material is elastically pressed to the stopper member 54 and the outer column 2b in the circumferential direction of the outer column 2b.

The invention relates to a process for extracting high-grade rice bran oil by a physical method, which utilizes the partial pressure of water vapor to reduce the partial pressure of free fatty acids in the oil and also reduce the boiling point temperature of the free fatty acids under high vacuum conditions, so that the free fatty acids can also be gasified at a lower temperature (240 DEG C) lower and further be separated from the oil. The chemical refining aims to further reduce the acid value, and ensure the oil color; while the process adopts the three-time bleaching and deodorization combining method to achieve the purpose. The three-time bleaching is that a mixing bleaching agent is used to remove 'blue' and other pigments produced in the deacidification process, and the deodorization is that the water vapor distillation principle is utilized to further remove the free fatty acids in the oil, so that the acid value and the like meet the requirements of product quality standards. Compared with the existing refining process, the process has high yield increasing by about 2-3% under the same conditions, and large micronutrient retention capacity, greatly retains nutrients, and significantly reduces the discharge amount of sewage.

The invention discloses a self-compacting concrete and belongs to the technical field of concrete. The self-compacting concrete comprises the following components in parts by weight: 350-400 parts of cement, 54-80 parts of coal ash, 52-60 parts of slag powder, 50-62 parts of expanding agent, 9-13 parts of silica powder, 748-800 parts of mixed sand, 948-1020 parts of macadam, 140-165 parts of drinking water, 0-10 parts of compound additive and high-performance additive being 1-2% of the binding material in mass fraction. The concrete acquired according to the invention has excellent self-compacting property, fluidity, collapse prevention, cohesiveness and separation resistance, and meanwhile, a test proves that the compressive strength after 7 days is about 57MPa and the compressive strength after 28 days is about 70MPa, so that the concrete provided by the invention has higher compressive strength.