9results about How to "Strong retention" patented technology

The invention discloses a probiotic / mucoprotein loaded oral microsphere system as well as a preparation method and application thereof, and belongs to the field of compositions. The preparation method of the system comprises the following steps: dissolving probiotics, Mucin and HAMA in double distilled water containing phenyl lithium phosphate LAP and calcium chloride to prepare a gel matrix solution; adding the dissolved gel matrix liquid into an oil phase solvent, and stirring at a high speed in a container; after uniformly stirring, carrying out an ultraviolet light crosslinking reaction, and after the reaction is finished, fully cleaning the obtained microspheres to remove the redundant oil phase solution, so as to obtain microspheres; and dispersing the obtained microspheres in a sodium alginate solution under an acidic condition, uniformly mixing, carrying out a cross-linking reaction, and filtering and cleaning after the reaction is finished, so as to obtain the probiotic / mucoprotein loaded oral microspheres. According to the invention, HAMA and SA are utilized to prepare an oral microsphere system resistant to gastric acid to co-deliver Mucin and EcN, so as to realize continuous and effective regulation and control of unbalanced intestinal flora by probiotics.

An adhesive composition comprising a copolymer (A), a crosslinking agent (B), and an aqueous medium, wherein the copolymer (A) has structural units derived from a monomer (a1), structural units derived from a monomer (a2) having a carboxyl group, and structural units derived from a monomer (a3) ​​having an alkoxysilyl group, wherein the monomer (a1) is composed of either or both of an alkyl (meth)acrylate having only one olefinic double bond and a hydrocarbon having only one olefinic double bond, wherein the structural units in the copolymer (A) derived from the monomer (a2) are relative to those derived from the monomer (a1). The content of the structural unit in the copolymer (A) is 1.0 part by mass or more and 12 parts by mass or less in 100 parts by mass, and the content of the structural unit derived from the monomer (a3) ​​in the copolymer (A) is 0.010 parts by mass or more and 3.5 parts by mass or less in 100 parts by mass relative to the structural unit derived from the monomer (a1). The crosslinking agent (B) contains one or more selected from polycarbodiimide compounds, polyepoxide compounds and polyisocyanate compounds, and the content of the crosslinking agent (B) is 0.010 parts by mass or more and 10 parts by mass or less in 100 parts by mass relative to the copolymer (A).

The present invention discloses a high-resolution remote sensing image fusion method based on ICGAN, and belongs to the field of image fusion technology. The present invention comprises acquiring remote sensing image data to construct an ICGAN model, training the model based on the remote sensing image data using a generator and a discriminator; using the generator to generate a high-resolution multispectral image, using the discriminator to distinguish the true from the false of the output result of the generator; finally, testing the model based on the trained generator, and comparing and analyzing the test results. The present invention has a strong ability to retain the spectral information of low-resolution multispectral images and the spatial information of panchromatic images, and the spatial details and texture features of the ICGAN fused image are richer, and the effect is better than other fusion methods.

The invention discloses a full-dentition anchorage spiral expansion device, and relates to the technical field of orthodontic medical instruments. Comprising a spiral expander, a left anchorage assembly and a right anchorage assembly, the orthodontic device is characterized in that each anchorage assembly comprises a groove-shaped metal full crown covering the occlusal surface, the cheek side surface and the lingual side surface of a plurality of rear teeth on the same side, an arch expansion tongue rod fixedly connected with the near-middle lingual side surface of the metal full crown on the same side, and an arch expansion cheek rod fixedly connected with the near-middle cheek side surface of the metal full crown on the same side; the device is high in retention force, high in bony expansion efficiency, good in tooth protection, high in patient comfort level and wide in application range.

The present invention provides a crosstalk-proof high-speed connector, including a socket, a slot provided on the socket, a plurality of first terminal slots and a second terminal slot provided at both ends of the slot, a first terminal fixed in the first terminal slot, the first terminal including a first welding portion, a first transmission portion, a first bending portion, and a first contact portion, the first bending portion is bent toward the second terminal, the first transmission portion is provided with a first positioning slot, a first notch slot is provided on the end face away from the second terminal, a first positioning block matching the first positioning slot is provided on the inner side of the first terminal slot, a first hot melt plate is connected to the front end of the first terminal slot, and a first protrusion matching the first notch slot is connected to the inner side of the first hot melt plate. The high-speed connector of the present invention has a simple structure, a high signal transmission speed, excellent terminal retention force, and can avoid low impedance and crosstalk problems.

The invention discloses a goaf fire preventing and extinguishing method based on wind flow distribution and dry ice phase change. The method comprises the following steps that the wind flow intersection condition of a goaf and a coal face is measured; detecting the influence range when the dry ice is sublimated into CO2 gas in a laboratory; putting dry ice in the goaf; during stoping, after the goaf roof collapses, the goaf roof coal rock falls onto the heat preservation box filled with the dry ice, the heat preservation box is broken, and the dry ice is buried by the goaf roof coal rock and sublimates to form CO2 gas which is diffused all around for fire prevention and extinguishment. According to the method, the heat preservation boxes filled with the dry ice are arranged in the direction parallel to the coal face and are divided into sections according to wind flow intersection in the goaf, and it is guaranteed that CO2 gas formed after sublimation of the dry ice is evenly distributed in the goaf to the maximum extent. The dry ice in the heat preservation box does not generate phase change when being located in a heat dissipation zone, and sublimates after being smashed by goaf roof coal rocks after falling down when being located in an oxidation zone where spontaneous combustion is most likely to happen, and accurate fire prevention and extinguishing are achieved.

The invention discloses a method for determining 4-hydroxy-7-phenoxyisoquinoline-3-methyl formate and related substances, and belongs to the technical field of drug analysis. The method adopts reverse phase liquid chromatography to detect and analyze 4-hydroxy-7-phenoxyisoquinoline-3-methyl formate and related substances impurities A, impurity B, impurity C, impurity D, and impurity E, and uses octadecylsilane bonded silica gel as a chromatographic column as a filler, mobile phase A is trifluoroacetic acid aqueous solution, mobile phase B is acetonitrile, and gradient elution is adopted. The method has the advantages of high sensitivity, accurate impurity content determination results, good specificity, repeatability and linearity.

This invention provides a method for detecting trans-4,5-epoxy-2(E)-decaldehyde based on LC-MS / MS. First, trans-4,5-epoxy-2(E)-decaldehyde standards are prepared into standard solutions of different concentrations. Then, the standard solutions are derivatized by solid-phase extraction with 2,4-dinitrophenylhydrazine (DNPH) to obtain analytical samples containing standard solutions of different concentrations. Next, LC-MS / MS analysis is performed on the analytical samples of different concentrations of standard solutions to obtain a standard curve with standard concentration as the abscissa and peak area as the ordinate. The sample to be tested is detected using LC-MS / MS, and the content of trans-4,5-epoxy-2(E)-decaldehyde in the sample is determined using the standard curve. This invention achieves accurate qualitative and quantitative analysis of this compound and establishes a standardized platform for the role of this compound in systemic health and disease.