44 results about "Functionalized polyethylene" patented technology

An extreme-cold resistant low-fume halogen-free flame-retardant polyolefin sheath, a preparation method therefor, and a cable. The sheath comprises the following raw materials in parts by mass: 4-16 parts of an ethylene-vinyl acetate copolymer, 7-13 parts of a phosphate group functionalized linear low-density polyethylene, 9-15 parts of an ethylene-octene copolymer, 5-10 parts of a maleic anhydride-grafted ethylene-methyl methacrylate copolymer, 10-15 parts of magnesium hydroxide, 40-50 parts of aluminum hydroxide, etc. The preparation method for the phosphate group functionalized linear low-density polyethylene comprises: adding a catalyst to a pre-cooled ethylene monomer, adding a vinyl phosphate ester and an initiator after the reaction, and reacting for 1-2 hours at a temperature of 65-75°C and a pressure of 15-35 Mpa and then terminating the reaction, thereby obtaining the phosphate group functionalized linear low-density polyethylene. Compared with unfunctionalized polyethylene, the phosphate group functionalized polyethylene used has greatly improved low-temperature and flame-retardant performance, and can improve the overall flame-retardant and low-temperature performance of the formula.

The invention discloses a fluorinated polymer and application thereof in an electrode protection layer and a solid electrolyte, and belongs to the technical field of lithium metal secondary batteries, and the fluorinated polymer is obtained by reacting acrylate functionalized polyethylene glycol, HFBA and an initiator. When the fluorinated polymer is used as a lithium metal negative electrode protective layer, the LiFePO4 / Li total battery protected by the polymer shows more excellent cycle performance compared with an unprotected total battery. And the battery is stable in cycle performance, high in capacity retention rate and low in capacity fading speed. When the fluorinated polymer is applied to the solid-state electrolyte, the polymer solid-state electrolyte in which a polymer network wraps an ionic conductive plastic crystal can be formed through an in-situ reaction, so that the growth of Li dendritic crystals is effectively inhibited, and the stability of the polymer electrolyte and a lithium negative electrode is ensured. Moreover, the solid electrolyte can be adapted to a high-nickel ternary positive electrode material, and a thought is provided for realizing a stable and safe high-energy-density battery.

The application discloses a high-temperature-resistant power cable and a preparation method thereof. A copper conductor is twisted to form a core, and an insulating layer, a shielding layer and a protective layer are sequentially coated on the surface of the core to obtain the high-temperature-resistant power cable. The protective layer is a reinforced resin, and the reinforced resin comprises the following raw materials in parts by weight: 100-120 parts of functionalized polyethylene, 20-30 parts of modified filler, 0.5-0.8 parts of p-toluenesulfonic acid and 10-15 parts of 1,4-p-biphenyl boronic acid bis(pinacol) ester. The functionalized polyethylene and the modified filler form an organic-inorganic interpenetrating network under the action of the 1,4-p-biphenyl boronic acid bis(pinacol) ester. The modified filler can form a thermal barrier network in the whole matrix, effectively hinders the thermal motion of the polyethylene molecular chain, and the side chain of the functionalized polyethylene molecular chain contains a phenyl polysiloxane structure, which can increase the flexibility of the polyethylene chain segment. In combination with the formation of dynamic crosslinking, the high-temperature-resistant effect of the material is greatly improved.

The present application relates to the technical field of high polymer material modification, and particularly relates to a kind of heat-reversible crosslinking polyethylene material based on Diels-Alder synthesis and a preparation method thereof.The preparation method comprises: maleic anhydride polyethylene is melt grafted with excess furan methylamine, then is treated by high temperature and high pressure dehydration ring closure to form stable furan functionalized polyethylene; then melt blend with bismaleimide, and by low temperature long time annealing treatment, to promote Diels-Alder reaction to proceed fully, so as to build a perfect heat-reversible crosslinking network.The present application has the beneficial effects that the obtained heat-reversible crosslinking polyethylene material has excellent temperature mechanical strength, solvent resistance and clear heat-reversible characteristics, and can be uncrosslinked at higher than 150 DEG C to realize melt reprocessing, and the network is reconstructed after cooling, and the strength retention rate is still higher after two times of recycling.The present application solves the problem of non-recyclable traditional crosslinking polyethylene, and is particularly suitable for recyclable products such as packaging and pipe.

The invention provides an antistatic packaging wrapping film and a preparation method thereof. A polymer layer comprises the following components in percentage by mass: 75-85% of modified polyethylene, 5-15% of intelligent response type copolymer, 0-2% of nano filler, 3-8% of furan functionalized polyethylene, 0.5% of a lubricant, 0.2% of an antioxidant and 0.1% of a light stabilizer. The core layer comprises the following components in percentage by mass: 75-85% of polyethylene, 10-20% of a block copolymer, 5% of a tackifier, 0.5% of a processing aid and 0.2% of an antioxidant; the conductive layer comprises the following components in percentage by mass: 85-90% of polyethylene, 8-15% of composite conductive filler master batch, 1-3% of a functional aid, 0.2% of an antioxidant and 0.1% of an ultraviolet absorbent; through the design of a three-layer composite structure, the transparent antistatic wrapping film integrates efficient antistatic property, intelligent humidity response, potential self-repairing and excellent mechanical property.

A multilayer polymer pipe including a first tubular layer, the first layer having as main component one or more polyethylene polymers and which layer further includes at least one compatibilizer, preferably a functionalized polyethylene polymer, a second layer surrounding the first layer, the second layer including one or more polyamide polymers and being substantially free of compatibilizer, a third layer surrounding the second layer, the third layer including one or more polyketone polymers and being substantially free of compatibilizer, a fourth layer surrounding the third layer, the fourth layer including one or more polyamide polymers and being substantially free of compatibilizer, a fifth layer surrounding the fourth layer, the fifth layer including as main component one or more polyethylene polymers and which further includes at least one compatibilizer, preferably a functionalized polyethylene polymer.

A device containing glass beads functionalized with polyethyleneimine which is adsorbed on the surface of the glass beads, and the use thereof for capturing microorganisms for implementing a method for removing microorganisms or for diagnosing. The microorganisms can be chosen in particular from bacteria and Fungi, in particular yeasts and fungi.

The application discloses a flexible mono-arylmethyl alpha-diimine palladium (II) catalyst and application thereof in catalytic polymerization of ethylene. The catalyst has 1,2-acenaphthene and 2,3-butanedione as a core skeleton, and successfully realizes high branching degree and wide molecular weight adjustment of polyethylene by skillfully introducing a flexible mono-arylmethyl structure. The catalyst has significant polymerization activity, which is between 1.6 and 15.1*10 4 g / (mol Pd·h). Compared with traditional rigid ortho-aryl and ortho-di-arylmethyl Pd(II) catalysts, the flexible catalyst can significantly improve the branching density, and provides a highly flexible means for adjusting the viscosity of PAO lubricating oil base oil. In the copolymerization reaction of ethylene and methacrylic acid, the flexible catalyst also exhibits excellent performance, which is superior to rigid counterparts in promoting MA insertion, and further verifies the broad application prospect of the flexible catalyst in synthesis of polar functionalized polyethylene.

The invention relates to the technical field of bag-in-box BIB flexible packaging materials, and discloses a single-material flexible packaging film for manufacturing a cubic BIB liquid bag and a preparation method of the single-material flexible packaging film for manufacturing the cubic BIB liquid bag. Specifically, based on a hydroxyl-epoxy ring-opening reaction mechanism, hydroxyphenyl long-chain fatty amine monomers are modified on the surface of graphene rich in epoxy functional groups, and phenylated long-fatty-chain graphene is prepared; on the basis of a free radical addition reaction mechanism, octavinyl-POSS is grafted to a polyethylene main chain to prepare octavinyl-POSS functionalized polyethylene, and the octavinyl-POSS functionalized polyethylene is compounded with phenylated long aliphatic chain type graphene through a Friedel-Crafts reaction to prepare the high-performance polyethylene master batch. The high-performance polyethylene master batch is used as a modification component of single polyethylene resin, the single-material flexible packaging film is prepared through a nine-layer co-extrusion blow molding process, and the film product has excellent mechanical performance, oxygen resistance and recoverability, can be used as a cubic BIB liquid bag material and is used for manufacturing bag-in-box BIB.

The invention relates to the technical field of biological medicine, in particular to functionalized lipopeptide and a preparation method thereof, a functionalized lipopeptide-assisted nucleic acid drug lipid nano delivery system and application thereof. The functionalized lipopeptide is a compound formed by functionalized polyethylene glycol-lipid and partially or completely exposed amino groups of the functionalized hybrid polypeptide through a click chemical reaction or a Michael addition reaction; the functionalized hybrid polypeptide is a compound formed by an esterification reaction of an N-hydroxysuccinimide-polyethylene glycol-group and partially or completely exposed amino groups of the functionalized polypeptide. The lipopeptide provided by the invention is simple in preparation process and low in toxicity, and the lipopeptide-assisted nucleic acid drug lipid nano delivery system can realize high-efficiency delivery of various nucleic acid molecules such as siRNA, mRNA and DNA in vitro and in vivo and has a treatment effect on various diseases.

The application relates to the technical field of bag-in-box (BIB) flexible packaging materials, and discloses a single-material flexible packaging film for manufacturing a cubic BIB liquid bag and a preparation method, which is characterized by the following steps: based on a hydroxyl-epoxy ring-opening reaction mechanism, a hydroxyl phenyl long-chain aliphatic amine monomer is modified on a graphene surface rich in epoxy functional groups to prepare phenylated long aliphatic chain graphene; based on a free radical addition reaction mechanism, octavinyl-POSS is grafted to a polyethylene main chain to prepare octavinyl-POSS functionalized polyethylene, and the high-performance polyethylene master batch is prepared by compounding the octavinyl-POSS functionalized polyethylene and the phenylated long aliphatic chain graphene through a Friedel-Crafts reaction; the high-performance polyethylene master batch is used as a modified component of single polyethylene resin, and a single-material flexible packaging film is prepared through a nine-layer co-extrusion blowing process; the film product has excellent mechanical properties, oxygen barrier properties and recyclability, can be used as a cubic BIB liquid bag material, and can be used for manufacturing a bag-in-box (BIB).

The invention discloses a high-temperature-resistant power cable and a preparation method thereof, copper wires are twisted to form a wire core, the surface of the wire core is sequentially coated with an insulating layer, a shielding layer and a protective layer, the high-temperature-resistant power cable is prepared, and the protective layer is reinforced resin. The reinforced resin comprises the following raw materials in parts by weight: 100-120 parts of functionalized polyethylene, 20-30 parts of a modified filler, 0.5-0.8 part of p-toluenesulfonic acid and 10-15 parts of 1, 4-bis (pinacol) diphenylboronic acid, the functionalized polyethylene and the modified filler form an organic-inorganic interpenetrating network under the action of the 1, 4-bis (pinacol) diphenylboronic acid, and the organic-inorganic interpenetrating network is formed by the modified filler and the 1, 4-bis (pinacol) diphenylboronic acid under the action of the 1, 4-bis (pinacol) diphenylboronic acid. The modified filler can form a thermal barrier network in the whole matrix, thermal motion of a polyethylene molecular chain is effectively hindered, meanwhile, a side chain of the functionalized polyethylene molecular chain contains a phenyl polysiloxane structure, the flexibility of a polyethylene chain segment can be improved, and the high-temperature-resistant effect of the material is greatly improved through cooperation with dynamic crosslinking.

The present invention relates to an article comprising a support at least partially provided with a coating, wherein i) the support comprises or consists of a thermoplastic composition comprising a polycarbonate, ii) the coating is applied directly on the support and comprises or consists of a polyurethane obtained by reacting at least one di- or tri-isocyanate and at least one polyol, iii) the polycarbonate comprises at least 50 wt% of a first polycarbonate based on the weight of the polycarbonate, the first polycarbonate having an end hydroxyl content of at least 500 ppm, and wherein the thermoplastic composition comprises a polymer selected from the group consisting of polyethylene terephthalate, polybutylene terephthalate, acrylonitrile-butadiene-styrene copolymer, styrene-acrylonitrile copolymer, optionally functionalized polypropylene, optionally functionalized polyethylene, optionally functionalized polyolefin elastomer, (meth)acrylic-polybutadiene core-shell copolymer and a mixture of at least two of the foregoing.

According to various embodiments, an extruded foam is formed from a composition comprising 1 to 99 weight percent of a silicone-functionalized polyethylene comprising the reaction product of the polymerization of ethylene and a (meth)acrylate-functionalized polydimethylsiloxane, and a physical blowing agent. The foam has a density of 0.200 g / cm3 or less as measured according to ASTM D1622-88 at 25°C. 3 It has the following density:

The invention relates to the technical field of cables, in particular to a preparation process of a high-temperature-resistant tensile cable. According to the process, a dynamic borate and irreversible bismaleimide double-network synergistic structure is adopted, and polydopamine modified hexagonal boron nitride nanosheets and catechol-terminated perfluoropolyether are combined, so that molecular interface enhancement and directional heat conduction of the composite material are realized; comprising the following steps: preparing functional polyethylene master batch, blending and granulating functional filler and polymer master batch, thermally stretching and spirally winding to prepare a cable insulating layer, and performing vacuum hot pressing and steam crosslinking to form the cable insulating layer. The result shows that the cable has the advantages of high mechanical strength, good creep resistance, low dielectric loss, high insulating property and good process compatibility under the working conditions of high temperature (150 DEG C) and high tension, and is suitable for application in extreme environments.

This invention discloses a PSMA-targeted zwitterionic functionalized gold nanostar composite and its applications. The invention uses hyperbranched polyethyleneimine (PEI.NH2) as a carrier, and sequentially modifies its surface with diethylenetriaminepentaacetic acid dianhydride (DTPA), succinimide ester-polyethylene glycol-PSMA targeting ligand NHS-PEG-ACUPA, succinimide ester-polyethylene glycol-thiol NHS-PEG-SH, and fluorescein isothiocyanate (FI). The composite is further modified by chelating gadolinium ions (Gd) with diethylenetriaminepentaacetic acid dianhydride. 3+ Finally, functionalized polyethyleneimine was linked to alkoxyphenylsulfonamide-modified gold nanostars APAS-Au NSs via gold-sulfur bonds. The resulting gold nanostar complex can achieve efficient enrichment in prostate cancer cells and has CT / MR dual-modal imaging and photothermal therapy functions.

An article comprising at least one metal layer, at least one polypropylene layer, and a coextruded multilayer adhesive film that adheres the polypropylene layer to the metal layer. The coextruded multilayer adhesive film includes at least a first layer and a second layer. The first layer comprises crystalline block composite (CBC) including a crystalline ethylene-based polymer (CEP) comprising at least 60 mol %polymerized ethylene by weight of the CEP, an alpha-olefin-based crystalline polymer (CAOP) and a block copolymer including an crystalline ethylene block (CEB) comprising at least 60 mol %polymerized ethylene by weight of the CEB and a crystalline alpha-olefin block (CAOB). The second layer comprises functionalized polyethylene including polyethylene grafted with ethylenically unsubstituted dicarboxylic acid or derivative thereof.

The invention discloses hemostatic gel which comprises two components, one component is a mixture of gelatin short fibers and HA-A-Ald, and the other component is 8-arm-PEG-SH. The invention also discloses a preparation method. According to the invention, sulfydryl in eight-arm polyethylene glycol mercaptan and aldehyde group in HA-A-Ald can react with amino of protein in natural tissue, meanwhile, the sulfydryl in the eight-arm polyethylene glycol mercaptan and double bonds in HA-A-Ald generate covalent bond combination, and the aldehyde group in HA-A-Ald and amino in gelatin short fiber generate Schiff base covalent crosslinking, so that the hydrogel is obtained. And the wound sealing effect is achieved. The gelatin short fiber has a high specific area, and can quickly adhere a large amount of blood cells and blood platelets to accelerate physical blood coagulation; meanwhile, the polyethylene glycol and the hyaluronic acid have high moisture retention, and the hemostatic gel formed by the functionalized polyethylene glycol and the hyaluronic acid has a porous structure, so that plasma components in blood can be rapidly adsorbed, and rapid hemostasis is realized.

The application belongs to the technical field of medicine, and discloses a nano-carrier capable of penetrating through the blood-brain barrier and improving brain delivery efficiency, and a preparation and application thereof. The preparation method comprises the following steps: 1) dopamine hydrochloride is deposited on the surface of nanoparticles through an oxidative self-polymerization reaction to obtain polydopamine modified particles; and 2) glucose functionalized polyethylene glycol and end-capped polyethylene glycol are reacted with the polydopamine modified particles to obtain the nano-carrier. The polydopamine coating is used to modify the nanoparticles, and the glucose functionalized polyethylene glycol is used to secondarily modify the polydopamine coating, so that the ability of the nanoparticles to penetrate through the BBB and enter brain tissues and brain gliomas is enhanced. The targeting effect of the glucose functionalized PEG and the synergistic effect of the PDA coating in enhancing cell uptake are combined in the application, so that the brain and brain tumor delivery capacity of the nano-carrier is enhanced. The nano-carrier is used for loading drugs.

A multilayer structure comprising an aluminum substrate, a polymeric layer, and at least one tie layer adhering the polymeric layer to the aluminum substrate, wherein the tie layer comprises: a polyethylene comprising one or more linear low density polyethylene resins and having a melt index (I2) of 0.5 dg / min to 10 dg / min as determined according to ASTM D1238 (190°C / 2.16 kg); a functionalized polyethylene having a melt index (I2) of 1.0 dg / min to 10.0 dg / min, wherein the functionalized polyethylene comprises a polyethylene grafted with an ethylenically unsubstituted dicarboxylic acid or a derivative thereof; a polystyrene having a Vicat softening temperature higher than 90°C; and a modifier comprising one or more of very low density polyethylene, polyolefin elastomer, ethylene acid copolymer, olefin block copolymer, ethylene alkyl acrylate copolymer, and ethylene propylene diene terpolymer.

The present invention relates functionalised polyvinyl acetal films with a high molecular weight and laminated glass comprising a such functionalised films sandwiched between two sheets of glass.

The application relates to the technical field of container liquid bag material research and development, and discloses a composite film for manufacturing a container liquid bag and a preparation process, in particular to the following: based on a Friedel-Crafts alkylation reaction mechanism, a phenyl-POSS functionalized polyethylene and a phenyl-POSS functionalized polypropylene are grafted on the surface of an alkenyl functionalized sheet spacing stable montmorillonite to prepare an organic-inorganic hybrid high-strength filler for modifying a polyolefin base, and through a 11-layer co-extrusion blow molding process, a composite film is prepared; the film product meets the technical requirements stipulated in the TB / T 2689.4-2018 "Railway Freight Containerization Transportation Part 4: Disposable Container Liquid Container Bag" standard and can be used as the inner bag material of the disposable container liquid bag.

The invention relates to the technical field of special high polymer materials, in particular to polyetherimide polyethylene composite bonding resin with high heat resistance and high bonding performance and a preparation method of the polyetherimide polyethylene composite bonding resin. 3 to 8 parts of polytetrafluoroethylene ultrafine powder plasticized by ionic liquid; 5-12 parts of a liquid metal core-shell structure filler; 15 to 30 parts of bio-based polyetherimide with a carbodicyclic structure; 35 to 55 parts of cyclodextrin coated metallocene polyethylene; 25 to 45 parts of radiation grafting functionalized polyethylene; 4-9 parts of a boron-silicon-containing double-bond functional monomer; 2 to 6 parts of hyperbranched polysiloxane; 1-4 parts of a rare earth complex antioxidant; and 20-35 parts of a polyurethane, epoxy resin and acrylate ternary complex. Wherein the porous ceramic microspheres enhance the mechanical strength and the thermal stability, so that the synergistic improvement of the bonding strength and the thermal stability of the polyetherimide polyethylene composite bonding resin in a high-temperature environment is realized.

A composition comprising a ternary phase polymer composite, the ternary phase polymer composite comprising component (A) having a γ of ≤5 mN / m to ≥1 mN / m P Ethylene / unsaturated ester copolymer; at least two other polymers selected from the group consisting of: (B) having ≥ 0mN / m to <1mN / m γ P a non-polar polymer selected from the group consisting of polyethylene homopolymers, silane-functionalized polyethylene homopolymers, ethylene / α-olefin copolymers, and silane-functionalized ethylene / α-olefin copolymers; (C) having a γ of >5 mN / m P (A) and only one of the at least two other polymers, wherein (i) one of the at least two other polymers is selected from (B) and the other is selected from (C) or (D), or (ii) one of the at least two other polymers is selected from (C) and the other is selected from (B) or (D).

A coated substrate includes a polar layer, at least one polypropylene layer, and at least one adhesive layer adhering the polypropylene layer to the polar layer, wherein the adhesive layer comprises: a crystalline block composite (CBC) component comprising an ethylene polymer (EP) comprising at least 90 mol% polymerized ethylene based on the weight of the ethylene polymer, an alpha-olefin based crystalline polymer (CAOP), and a block copolymer comprising an ethylene polymer block and a crystalline alpha-olefin block (CAOB), the ethylene polymer block comprising at least 90 mol% polymerized ethylene based on the weight of the ethylene polymer block; a functionalized polyethylene having a melt flow rate MFR (190°C / 2.16 kg) of 1.0 dg / min to 10.0 dg / min as determined according to ASTM D1238, wherein the functionalized polyethylene comprises a polyethylene grafted with an ethylenically unsubstituted dicarboxylic acid or a derivative thereof; and a modifier comprising a polyolefin elastomer.

The invention belongs to the technical field of polyolefin, and particularly relates to a preparation method of functionalized polyolefin for a high-filling flame-retardant cable. According to the preparation method disclosed by the invention, a polyolefin matrix is subjected to melt grafting through MAH / St double monomers, and core-shell-surface gradient structure functionalized polyethylene wax is synergistically introduced, so that a multi-layer tough interface system is constructed. The MAH / St grafted chain provides a polar site, and the polyethylene wax takes an annular surface layer and a nano SiO2 core as an interface bridging anchoring point, so that agglomeration of a high-content flame retardant is inhibited, a filling weak point is converted into a toughening point, LOI and UL94 V-0-level flame retardant performance is remarkably improved, the tensile strength and the elongation at break are synchronously improved, and the problems of high filling embrittlement and performance degradation are solved. Meanwhile, by means of narrow-distribution polyethylene wax prepared through controllable polymerization and a compound antioxidant system, intrinsic thermal stability and aging resistance of the material are synergetic, T5% is remarkably higher than that of a conventional system, it is guaranteed that the cable operates for a long time and is stable in performance under short-time overload, thermal aging failure is delayed, and safety and reliability of long-term operation are improved.

The invention discloses a preparation method and application of multifunctional hydrogel with a space-time cascade repair mechanism. The preparation method comprises the following steps: based on norbornene modified 8-arm polyethylene glycol, forming a covalent cross-linked network through a thiol-norbornene light click reaction initiated by ultraviolet rays; and S-nitroso glutathione functionalized polyethylene glycol macromolecules and calcium ion chelated nanoparticles SPCa < 2 + > are loaded. The hydrogel precursor also includes an MMP sensitive peptide, a photoinitiator LAP, and an RGD peptide. Through multiple synergy among photo-thermal sterilization, promotion of angiogenesis by NO and promotion of osteogenic differentiation by Ca < 2 + >, an antibacterial-vascularization-repair integrated delivery system is constructed, a new strategy is provided for precise synergistic treatment of infectious bone defects, and the system has important scientific research value and wide clinical transformation prospects.

The invention discloses a manganese dioxide-based nano sound-sensitive vaccine as well as a preparation method and application thereof. The manganese dioxide-based nano sound-sensitive vaccine comprises a manganese dioxide-based nano carrier, a sound-sensitive agent and functionalized polyethylene glycol, the sound-sensitive agent is loaded on the nano carrier through a Mn-N coordination bond, and the polyethylene glycol is connected to the surface of the nano carrier through a covalent bond. The capability of generating OH by sonodynamic is improved by biotinylating a xanthene sound-sensitive agent rose bengal, meanwhile, MnO2 nanoparticles are adopted as a sound-sensitive vaccine carrier, in-situ generation and release of oxygen are realized, and the sound-sensitive agent is promoted to generate more < 1 > O2 in an oxygen-dependent way. According to the manganese dioxide-based nano sound-sensitive vaccine, the consumption of GSH (glutathione) in tumor cells on ROS (reactive oxygen species) is blocked in a targeted manner. According to the nano sound-sensitive vaccine, by increasing accumulation of ROS, severe tumor cell killing is caused, a more effective ICD effect is triggered, meanwhile, Mn < 2 + > is released in situ at a tumor site to activate a cGAS-STING pathway, an immunosuppressed tumor microenvironment is cooperatively regulated, in-vivo immune response is enhanced, and sonodynamic-immune combined treatment is achieved.

This disclosure provides a method for preparing nanoparticles, the method comprising: mixing amino-functionalized polyethylene nanoparticles with nano-metal particles to obtain polyethylene nanoparticles with the nano-metal particles bound to their surface; mixing the polyethylene nanoparticles with the nano-metal particles bound to their surface with triethanolamine, hexadecyltrimethylammonium bromide, and tetraethoxysilane to obtain polyethylene nanoparticles coated with a mesoporous silica shell; and calcining the polyethylene nanoparticles coated with the mesoporous silica shell to obtain calcined particles. This disclosure also provides the nanoparticles prepared by this method and their use in the preparation of surface-enhanced Raman scattering (SERS) detection kits. The nanoparticles of this disclosure further mitigate the "protein crown" effect of SERS-labeled nanoprobes, improving the stability and accuracy of the Raman signal.

A multilayer polymer tube comprising:-a tubular first layer (1) comprising, as a main component, one or more polyethylene polymers, and said layer further comprising at least one compatibilizer, preferably a functionalized polyethylene polymer; -a second layer (2) surrounding said first layer, said second layer comprising one or more polyamide polymers and being substantially free of compatibilizers; -a third layer (3) surrounding said second layer, said third layer comprising one or more polyketone polymers and being substantially free of compatibilizers; -a fourth layer (4) surrounding said third layer, said fourth layer comprising one or more polyamide polymers and being substantially free of compatibilizers; -a fifth layer (5) surrounding said fourth layer, said fifth layer comprising, as the main component, one or more polyethylene polymers and further comprising at least one compatibilizer, preferably a functionalized polyethylene polymer.