100 results about "Snake venom" patented technology

The method is mainly applied to the technical field of deep learning. The invention discloses an intelligent diagnosis method, device and equipment for snake venom poisoning and a medium, and the method comprises the steps: obtaining multi-modal data which comprises a wound image, a symptom text and a blood parameter; performing feature extraction processing on the wound image, the symptom text and the blood parameters to obtain image features corresponding to the wound image, semantic features corresponding to the symptom text and high-dimensional features corresponding to the blood parameters; performing alignment and fusion processing on the image features, the semantic features and the high-dimensional features through a cross-modal attention mechanism to generate fusion features; after the fusion features are input into a preset multi-task classification model, classification is carried out in a snake species label space and a toxicity category space according to the fusion features, a poisoning grade score is determined, and a diagnosis report is generated based on the poisoning grade score. According to the invention, high-precision, rapid and intelligent diagnosis of snake venom poisoning can be realized.

The invention discloses an anti-aging and anti-wrinkle composition containing various polypeptides as well as a preparation method and application of the anti-aging and anti-wrinkle composition. According to the anti-aging and anti-wrinkle composition, various polypeptide components are compounded, a synergistic interaction system of the polypeptides is formed, acetyl hexapeptide-8 and snake venom-like peptide are taken as cores, and a dual inhibition pathway is established aiming at dynamic wrinkles; hexapeptide-9 and palmitoyl pentapeptide-4 are compounded to repair a matrix, and regeneration of corium layer structural protein is promoted; with the assistance of mu-conopeptide, palmitoyl tripeptide-1 and palmitoyl tripeptide-5, static wrinkle improvement and skin density improvement are enhanced; and finally, acetyl tetrapeptide-9 is assisted to activate elastin and optimize the contour supporting force, so that the synergistic effect of three effects of resisting wrinkles, tightening and repairing is realized, and the composition has more excellent inhibition rate of elastase and excellent free radical scavenging capacity, and achieves a remarkable antioxidant effect and an excellent anti-aging and anti-wrinkle effect.

The invention discloses a long-acting anti-aging composition capable of quickly removing dark circles and application of the composition. The composition is prepared from the following components: beta-nicotinamide mononucleotide, glutathione, acetyl hexapeptide-8, acetyl tetrapeptide-5, snake venom-like peptide, arginine / lysine polypeptide, tocopheryl acetate and ergothioneine. According to the present invention, multiple functions are adopted, such that the effects of dark circle removing, repair, elasticity recovery, aging resistance and the like are provided so as to block the generation of dark circle, and the normal function of skin is ensured. The composition disclosed by the invention has the effect of quickly removing dark circles, and when the eye cream contains the composition, the eye cream can effectively remove the dark circles and has an obvious and quick effect within 15 minutes; after being used for a long time, the eye mask can remove dark circles and play a good control role.

The invention relates to the technical field of cosmetics, in particular to a composition, a reagent, application of the composition and the reagent, a generation accelerant of type I collagen and type III collagen and cosmetics. The composition is prepared from the following components in parts by weight: 0.001 to 0.55 part of palmitoyl tripeptide trifluoroacetate, 0.001 to 1 part of methylsilanetriol and 0.001 to 0.55 part of snake venom-like tripeptide. According to the technical scheme provided by the invention, not only can the mitochondrial function be adjusted, but also the expression of HSP47 protein can be promoted, so that the collagen generation of dermis is promoted, the length and the quantity of nasolabial folds are reduced, the skin elasticity is improved, and a good anti-aging effect is shown.

The present invention relates to antigen-binding proteins capable of fully neutralizing snake venom PLA2 neurotoxin lethality, antigen-binding proteins capable of fully neutralizing snake venom short-chain alpha neurotoxin lethality, and oligoclonal antigen-binding mixtures capable of binding to, blocking, or neutralizing PLA2 neurotoxin and short-chain alpha neurotoxin from coral snake venoms. The invention also relates to pharmaceutical compositions, kit of parts and kits for the treatment and diagnosis of snake envenomation.

The invention discloses bee venom-containing skin essence with small irritation and a preparation method of the bee venom-containing skin essence. The skin essence is prepared from PLGA-PEG / liposome nanoparticles, a temperature-sensitive gel matrix, a protective agent, an antioxidant, a stabilizer and ultrapure water, the preparation method comprises the following steps: preparing the PLGA-PEG / liposome nanoparticles, preparing a poloxamer 407 solution, resuspending the nanoparticles, filling and storing. According to the invention, the melittin and the snake venom-like peptide have a synergistic effect on skin wrinkle resistance, so that the skin care effect is improved; pLGA-PEG / liposome nanoparticles are matched with a poloxamer solution to construct a dual sustained-release drug system, so that the irritation of drugs to skin is reduced, the lasting effect of the drug effect is improved, and the obtained skin essence has excellent moisturizing, whitening, anti-wrinkle and antioxidant capacities and is small in irritation.

The present invention provides a salmon mask with anti-inflammatory, anti-aging and repairing effects and a preparation method thereof, belonging to the field of cosmetic technology. The salmon mask includes the following components by weight: Phase A: 2-5 parts of aloe vera gel, 1-3 parts of sodium carrageenan, 2-4 parts of sodium alginate, 1-5 parts of konjac gum, 3-5 parts of glycerol and 85-95 parts of high-purity water; Phase B: 5-10 parts of polydeoxyribonucleotides, 10-25 parts of Centella asiatica extract, 10-25 parts of Portulaca oleracea extract, 5-15 parts of Calendula officinalis extract, 10-20 parts of hyaluronic acid, 2-5 parts of acetyl tetrapeptide-15, 1-3 parts of palmitoyl tetrapeptide-7, 1-3 parts of acetyl hexapeptide-8, 3-8 parts of conopeptide, 1-3 parts of snake venom tripeptide and 2-5 parts of pentapeptide-3. The present invention makes the obtained mask have better anti-inflammatory, moisturizing and repairing effects by selecting specific ingredients.

The invention relates to the technical field of detection kits, in particular to a blood coagulation reaction linked lupus anticoagulant fluorescence detection kit and application thereof, the kit contains a screening-confirmation integrated reagent, a calibration product, a quality control product and an anticoagulation interference inhibitor; the integrated reagent is divided into a reagent A and a reagent B, the reagent A contains a buffer solution, recombinant snake venom thrombin, composite phospholipid, a fluorescent substrate and other components, and the reagent B contains prothrombin, calcium ions, high-concentration composite phospholipid and other components; the composite phospholipid system is formed according to a specific proportion and modifies beta2-glycoprotein I, the fluorescence enhancement-stabilization system is formed by matching a Schiff base compound with a stabilizer, the calibrator is a series of lupus anticoagulant standard substances, and the quality control substance comprises simulants with different concentrations and negative control. The anti-interference capability is high, and the influence of anti-coagulant drugs and enzyme source fluctuation is reduced; the signal amplification effect is obvious, the detection sensitivity is high and the reagent stability is good; the operation is simple and convenient, screening and confirmation are integrally completed, and a conventional fluorescence detector is adapted.

The invention discloses a moisturizing anti-wrinkle polypeptide composition as well as a preparation method and application thereof, and relates to the technical field of daily chemical materials. The invention discloses a preparation method of a moisturizing and anti-wrinkle polypeptide composition, which comprises the following steps: uniformly stirring meadowfoam seed oil, caprylic acid / capric acid / succinic triglyceride and polypeptide liposome to obtain the moisturizing and anti-wrinkle polypeptide composition, wherein the polypeptide liposome is prepared by taking a combination of soybean lecithin, modified cholesterol and cholesterol as a capsule material and taking acetyl hexapeptide-8, snake venom peptide and a blue copper peptide compound as a core material through an ethanol injection method. The modified cholesterol is obtained by modifying cholesterol, the modified cholesterol is added into the capsule material, the defects that an existing liposome material is prone to aggregation and leakage, poor in stability and the like are effectively overcome, and the prepared material is good in stability, capable of being slowly released, high in skin retention amount and capable of being more easily absorbed by skin cells; the function of obviously delaying skin aging is realized.

The present application relates to the beer brewing technical field, especially a kind of venomous beer brewing process, including the following steps: raw material preparation and pretreatment;Saccharification;Filtering;Boiling;Rotary sedimentation;Fermentation;After mature wine, under low pressure 8.986kPa pressure, reduce the boiling point of water, ensure that the boiling point is lower than 25 degrees Celsius, concentrate wine, concentrate to 15 liters or less per 100 liters, carry out oak barrel barrel;Oak barrel barrel.The product is soft in taste, no spicy residue, alcohol burning sensation controllable;Flavor levels are rich, with fruit, flower, nut and other complex aroma;Process parameters are accurate, without low-temperature freezing equipment, small and medium-sized enterprises can replicate and the quality of stable venomous beer brewing process.

The application belongs to the technical field of biotechnology, and particularly relates to a kind of snake venom polypeptide and application thereof.The snake venom polypeptide is polypeptide DACU-1, polypeptide DACU-2 or polypeptide DACU-3.The application provides a kind of new snake venom polypeptide, including three polypeptides, and the three polypeptides all have anti-platelet aggregation activity, and have the activity of inhibiting platelet aggregation under the stimulation of ADP, arachidonic acid, collagen, thrombin and other various activators, and have the potential to be developed into anti-platelet drugs, functional foods and health products.

The invention relates to the technical field of in-vitro diagnosis, in particular to a lupus anticoagulant detection kit based on recombinant snake venom enzyme and application of the lupus anticoagulant detection kit. The probe comprises a recombinant snake venom thrombin-like enzyme, a phospholipid-quantum dot conjugate, calcium ions, sodium citrate, trehalose, polyethylene glycol, L-histidine, EDTA-2Na, a Tris-HCl buffer solution, a nanogold-carbon nanotube composite probe, a graphene oxide-chitosan composite material, a fluorescence enhancer and a stabilizer. The kit disclosed by the invention is high in detection sensitivity, strong in matrix interference resistance, excellent in recombinant snake venom enzyme stability and good in batch-to-batch consistency, the detection specificity can be accurately verified, and the problem that the performance of a traditional kit is poor is solved.

The invention relates to the technical field of daily chemicals, in particular to an anti-aging composition and application thereof. The composition is prepared from a white birch bark extract, snake venom peptide and Ectoine. The white birch bark extract promotes abnormal protein removal by activating an intracellular protein ubiquitination system, and improves the skin metabolism capability; the snake venom peptide slows down expression muscle contraction through a nerve regulation mechanism, and dynamic wrinkles are effectively faded; ectoin enhances cell membrane stability, protein protection and skin stress adaptive capacity, and under the synergistic effect of Ectoin, Ectoin and skin stress adaptive capacity, the comprehensive anti-aging effects of resisting wrinkles, tightening, relieving, brightening skin color and the like can be remarkably improved.

The invention discloses a whitening and anti-aging mask formula based on dogwood. The whitening and anti-aging mask formula based on dogwood is prepared from the following raw materials in parts by mass: 5 to 15 parts of dogwood extract, 2 to 8 parts of vitamin C powder, 1 to 3 parts of polyphenol compound, 1 to 5 parts of glycerinum, 2 to 4 parts of hyaluronic acid, 3 to 9 parts of plant essence, 2 to 6 parts of vegetable oil, 4 to 12 parts of seaweed extract and 1 to 3 parts of polyether-201. 1-3 parts of nerve growth factors, 2-6 parts of DNA (deoxyribonucleic acid) repair enzyme, 0.1-0.3 part of snake venom essence, 1-3 parts of plant stem cells and 20-30 parts of deionized water, components in the snake venom essence can stimulate synthesis of collagen and increase skin elasticity, so that wrinkles and fine wrinkles are reduced, the skin looks younger and tighter, certain antioxidant capacity is achieved, and the skin care effect is good. Free radicals can be neutralized, the damage of environmental pollution and ultraviolet radiation to the skin is reduced, and the aging process of the skin is delayed.

The present disclosure relates to bioactive peptides, compositions, methods of production, and uses of snake venom-based bioactive peptides as antitumor agents. The disclosed bioactive peptides are synthesized on the basis of the C-terminus of songtail toxin B and its derivatives. The disclosed peptides exhibit attenuated toxic effects and improved anti-tumor activity against tumor cells, particularly against triple negative breast cancer cells, compared to current standard care. Thus, the disclosed bioactive snake venom peptides derived from songtail toxins are used to modulate cell proliferation, apoptosis, necrosis and cycle progression of tumor cells, particularly triple negative breast cancer cells, providing suitable alternatives for separate or supplementary treatment of patients with invasive solid tumors.

1. Name of the product in this design: Snake Venom Detector (VENOMSCAN). 2. Purpose of this design: This design is used for snake venom detection. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention relates to the technical field of daily chemicals, in particular to an anti-aging composition containing DNA sodium and application of the anti-aging composition. The composition is prepared from DNA sodium, hydrolyzed elastin, collagen, snake venom tripeptide, vitamin E and sodium hyaluronate. According to the emulsion disclosed by the invention, various active ingredients such as the DNA sodium, the snake venom tripeptide, the elastin peptide, the low-molecular collagen peptide, the nicotinamide, the alpha-arbutin and the purple blue bletilla striata bulb fermentation liquor are organically combined, so that multiple anti-aging and whitening effects of resisting oxidation, inhibiting melanin synthesis, promoting collagen and elastin generation, improving uneven skin color and the like can be synergistically realized. Purple blue bletilla striata bulbs are subjected to lactobacillus-candida compound fermentation, the product does not contain coarse particles after refined filtration treatment, is clarified, is stable for a long time after being added into an emulsion system, and is not easy to separate out and precipitate or cause system layering. The emulsion is light in structure, not sticky and greasy, endows skin with soft and moist touch feeling, and is suitable for various skin types including sensitive skin, and active ingredients are easy to permeate and absorb.

The application discloses a vehicle-mounted snake venom processing device and a method for processing snake venom by using the same. The vehicle-mounted snake venom processing device comprises a vehicle body, a workbench and a power supply device arranged in the vehicle body, and the workbench is provided with a separation device, a drying device, a detection device and a storage device. The drying device comprises a vehicle-mounted freeze dryer and an oil-free vacuum pump, and the crude snake venom separated by the separation device is subjected to freeze drying to obtain freeze-dried snake venom powder. The detection device comprises one or more of an enzyme label instrument, an ultraviolet spectrophotometer and a moisture tester for detecting biochemical indexes of the freeze-dried snake venom powder. The storage device is used for storing the freeze-dried snake venom powder which passes the detection. The vehicle-mounted snake venom processing device has a compact structure and is convenient to move and use, is suitable for collecting and processing snake venom in the scattered snake breeding of present snake breeders, significantly shortens the snake venom processing time, effectively retains active ingredients of the snake venom, improves the medicinal value of the snake venom, and is favorable for classified storage of the snake venom through on-site detection and analysis.

The application relates to the technical field of peptide synthesis, and discloses a preparation method of a snake venom-like tripeptide, which comprises the following steps: condensing Boc-beta-Ala-OH and H-Pro-OMe, hydrolyzing the methyl ester groups to obtain Boc-beta-Ala-Pro-OH; condensing Boc-Gln-OH and benzylamine, and removing Boc to obtain H-Gln-NHBzl; then condensing Boc-beta-Ala-Pro-OH and H-Gln-NHBzl to prepare a polypeptide; and after the Gln in the polypeptide is subjected to Hofmann rearrangement, the Boc protection group in the polypeptide is removed to obtain the snake venom-like tripeptide. The preparation method adopts liquid-phase synthesis of the snake venom-like tripeptide, the synthesis route is short, the reaction condition is mild, special equipment and reagents are not needed, the operation steps are simplified, the process cost is reduced; the reaction reagents used are cheap and easy-to-obtain industrial reagents, the raw material cost is reduced; and the product purity can reach more than 99%.

The invention belongs to the technical field of medicine separation, and particularly relates to magnetic bead immobilized snake venom phospholipase A2 as well as a preparation method and application thereof. The preparation method comprises the following steps: carrying out a coupling reaction on ferroferric oxide nanoparticles and (3-aminopropyl)-triethoxysilane in an organic solvent, washing, and drying to obtain aminated magnetic beads; and activating the aminated magnetic beads with glutaraldehyde, incubating with a snake venom phospholipase A2 solution, and reacting to obtain the magnetic bead immobilized snake venom phospholipase A2. The magnetic bead immobilized snake venom phospholipase A2 prepared by the invention can be used for rapidly and accurately fishing the snake venom phospholipase A2 toxin antidote from a mixture system, and has a better application prospect in the field of snake venom antidote research.

The invention relates to the technical field of biological medicines, and relates to specific primers and a method for identifying coral snake, cobra, king cobra and snake venom source species thereof, and application of the specific primers and the method. Based on highly-conservative and specific DNA fragments contained in DNAs extracted from tissues and snake venom of bungarus multicinctus, cobra and king cobra, specific primers are respectively designed for the fragments, and the bungarus multicinctus, cobra and king cobra and snake venom source species can be accurately identified. The method can be used for identifying bungarus multicinctus, cobra, king cobra and snake venom source species of bungarus multicinctus, cobra, king cobra and snake venom source species of bungarus multicinctus and cobra venom source species of bungarus multicinctus and cobra venom source species of bungarus multicinctus and cobra venom source species of bungarus multicinctus and cobra venom source species of bungarus multicinctus The method is high in detection sensitivity, high in correct detection rate, free of cross reaction and simple in operation process, and has higher specificity compared with a traditional immunoassay method.

The invention provides a synthetic method of snake venom-like tetrapeptide. Specifically, the invention provides a method for preparing the snake venom-like tetrapeptide H-beta-Ala-Pro-Dab-D-Tyr-NH-Bzl in a reaction mode of combining a liquid phase and a solid phase. According to the preparation method, racemization of Pro and Dab can be avoided, the process route is stable and simpler, and the high-purity snake venom-like tetrapeptide can be conveniently prepared at lower cost.

The invention discloses a saussurea involucrata polypeptide and application thereof, and belongs to the technical field of polypeptides, the saussurea involucrata polypeptide comprises saussurea involucrata tripeptide-1, saussurea involucrata pentapeptide-4, saussurea involucrata tripeptide-5, saussurea involucrata hexapeptide-8, saussurea involucrata hexapeptide-9 or saussurea involucrata acyl snake venom tripeptide, and the saussurea involucrata polypeptide is prepared through an amide condensation method of saussurea involucrata acid. The invention has the following beneficial effects: the anti-wrinkle, firming, soothing and anti-oxidation effects of the thousand-day chrysanthemum acyl tripeptide-1, the thousand-day chrysanthemum acyl pentapeptide-4, the thousand-day chrysanthemum acyl tripeptide-5, the thousand-day chrysanthemum acyl hexapeptide-8, the thousand-day chrysanthemum acyl hexapeptide-9 or the thousand-day chrysanthemum acyl snake venom tripeptide have obvious effects on the anti-wrinkle, firming, soothing and anti-oxidation effects; particularly, the instant wrinkle removal effect is particularly outstanding.

The invention discloses a blood matrix liquid D-dimer, an FDP quality control product and a preparation method, and the preparation method comprises the following steps: adding thrombin into human mixed plasma to obtain a cross-linked fibrin clot, and carrying out washing, dissolving, inactivation and ultrafiltration treatment on the obtained cross-linked fibrin clot to obtain a D-D mother solution; the preparation method comprises the following steps: adding snake venom thrombin into human mixed plasma to obtain a non-crosslinked fibrin polymer, and carrying out washing, precipitation dissolution, inactivation and ultrafiltration treatment on the obtained non-crosslinked fibrin clot to obtain FDP mother liquor; a buffer agent, a stabilizer and a preservative are added into human serum to obtain matrix serum; the D-D mother liquor and the FDP mother liquor are respectively added into matrix serum, and the matrix serum added with the D-D mother liquor and the FDP mother liquor is filtered and frozen to obtain the D-D and FDP composite quality control product. The human matrix serum is adopted, and the difference between different detection systems is small.

The present invention relates to a pharmaceutical composition for preventing or treating rheumatoid arthritis, comprising snake venom derived from Agkistrodon piscivorus piscivorus or Naja melanoleuca, which are types of snakes, an extract thereof, or a fraction thereof; a quasi-drug composition; a food composition; a cosmetic composition; and a method of treating rheumatoid arthritis by using the composition. The snake venom derived from Agkistrodon piscivorus piscivorus or Naja melanoleuca of the present invention can improve, alleviate, or treat symptoms of rheumatoid arthritis, which is a kind of autoimmune diseases, and thus will be able to be widely used in the development of therapeutic agents for various autoimmune diseases including rheumatoid arthritis.

The invention discloses a high-purity cobra venom active peptide as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. Sequencing identification shows that the cobra venom active peptide is a brand-new cobra venom active peptide which is not disclosed in the prior art, and after purification, the HPLC (high performance liquid chromatography) purity of the cobra venom active peptide reaches 100%. The cobra venom active peptide has a good analgesic effect, the onset time of the analgesic effect is obviously shortened compared with that of cobratide, and the cobra venom active peptide is very suitable for being used as an analgesic drug.

The invention provides a cyclic peptide composition with an anti-aging effect, and belongs to the field of medicines and cosmetics. The polypeptide components of the cyclic peptide composition are cyclic peptide, snake venom-like peptide and collagen peptide, the concentration of the polypeptide components is 0.00001 ppm to 20% (w / w), and the cyclic peptide composition comprises a polypeptide combination and a tripeptide combination in pairs. Compared with a single polypeptide group, the polypeptide composition can more effectively promote the generation of collagen in the in-vitro skin and inhibit the generation of neuronal acetylcholine, the effect of the combination of the cyclopeptide, the snake venom-like peptide and the collagen peptide is optimal, and the effect of the combination of the cyclopeptide, the snake venom-like peptide and the collagen peptide is the second order, so that the combination of the cyclopeptide, the snake venom-like peptide and the collagen peptide has a synergistic interaction effect. Therefore, the cyclopeptide composition can be added into various products such as essence, face cream, sunscreen cream, toning lotion, emulsion, eye cream, facial mask, facial cleanser, face cleaning honey, gel, spray and the like, so that the anti-wrinkle and tightening effects of the products are improved.

The invention discloses an anti-inflammatory and anti-aging cosmetic capable of being used after medical art, belongs to the field of cosmetics, and particularly relates to a liquid compound which is prepared from a utility agent, an auxiliary agent and water and can be used in the cosmetics, and the auxiliary agent further comprises a thickening agent, a humectant and a preservative. The utility agent at least comprises an active matter, the active matter comprises at least one of acetyl hexapeptide-8, oligopeptide-1, snake venom-like peptide, carnosine, palmitoyl tripeptide-1, ACE lipidosome, a bifidus yeast fermentation product and a lysate, and an active agent can also be added into the utility agent. The liquid compound obtained by the invention has the advantages of no cytotoxicity, good safety, capability of promoting cell proliferation, good anti-inflammatory effect, good anti-aging effect, no irritation to skin and good anti-inflammatory effect after medical treatment.

The invention discloses a sweet protein homotrimer as well as a preparation method and application thereof, and belongs to the technical field of genetic engineering. According to the technical scheme, the strategy of self-assembly of interchain disulfide bonds mediated by a PCA trimerization structural domain is adopted, the PCA trimerization structural domain is derived from a C-terminal fragment of snake venom serine protease, a stable homotrimer is spontaneously formed through the interchain disulfide bonds under the oxidation condition, and the stable homotrimer is used as an artificial trimerization'molecular rivet '; the PCA trimerization structural domain fragment is fused with sweet protein, controllable trimer assembly can be achieved in cells and / or outside cells, and no extra cross-linking agent is needed. Based on this, a sweet protein homotrimer is obtained from a sweet protein monomer; the sweet protein homotrimer has good thermal stability and pH tolerance, and a new technical platform is provided for industrial production of high-sweetness and high-stability functional protein.

The invention relates to the field of cosmetics, in particular to blue copper peptide secondary polishing essence which has anti-aging and brightening effects and is suitable for sensitive skin and a preparation method of the blue copper peptide secondary polishing essence. The blue copper peptide secondary polishing essence is prepared from the following components in percentage by mass: 0.001 to 10 percent of beta-glucan solution, 1 to 10 percent of glycerol, 1 to 8 percent of 1, 2-pentanediol, 0.01 to 0.3 percent of xanthan gum, 0.01 to 0.2 percent of sodium hyaluronate and 0.001 to 0.1 percent of arginine; the preparation comprises the following components in percentage by weight: 0.1-5% of a snake venom-like peptide solution, 0.01-1% of an anti-allergy agent solution, 0.01-5% of a nonapeptide-1 solution, 0.0001-1% of a supramolecular blue copper peptide solution, 0.001-1% of blue copper peptide and the balance of water. According to the formula, all the components achieve a synergistic effect, the anti-aging repairing effect and the brightening effect are improved, meanwhile, the formula is mild, the formula can be suitable for sensitive skin, the product effect is more comprehensive, and therefore the application range of the blue copper peptide product can be widened.