14results about How to "Prolong clotting time" patented technology

This invention relates to the field of ceramic composite metal casting technology, and discloses a method and apparatus for producing ceramic composite iron-based wear-resistant castings. The production method involves treating ceramic particles with decontamination, coarsening, sensitization, activation, and chemical plating to obtain modified ceramic particles; mixing and stirring the modified ceramic particles and a coating material to obtain a ceramic preform; fully heating the ceramic preform; then removing it and placing it into a mold cavity to obtain a mold; heating the mold in a tank; pouring molten iron after heating; and cooling after casting to obtain the ceramic composite iron-based wear-resistant casting. This invention also discloses a production apparatus for ceramic composite iron-based wear-resistant castings. This invention, employing the above-mentioned method and apparatus for producing ceramic composite iron-based wear-resistant castings, promotes the composite of ceramic and molten metal from a casting process perspective, ensuring that the molten metal can penetrate the fine pores of the ceramic preform, resulting in a good interface bonding between the high-chromium cast iron and ceramic particles, without unbonded or microscopic gaps.

This invention belongs to the field of industrial solid waste resource utilization technology, and relates to a circulating fluidized bed ash-based cementitious material for road base courses and its preparation method. The raw materials for the road base course cementitious material are composed of the following mass parts: 29-43 parts of circulating fluidized bed ash, 16-27 parts of ground blast furnace slag, 3-6 parts of silica fume, 7-15 parts of P.O42.5 silicate cement, 0.1-0.4 parts of activator, and 27-30 parts of water. The circulating fluidized bed ash is prepared by mixing circulating fluidized bed fly ash and slag in a mass ratio of (2-5):(5-10). This invention effectively alleviates the problems of fast setting time and shrinkage cracking of traditional road base course cementitious materials by utilizing the characteristics of micro-expansion and long hydration time of circulating fluidized bed ash. The advantage of this invention is that it promotes the large-scale utilization of circulating fluidized bed ash and contributes to carbon emission reduction in the road sector.

The invention relates to the field of gypsum-based building materials, and particularly discloses a preparation method of a lysine-tannic acid compound retarder and a gypsum-based building material.The preparation method comprises the following steps that 1, tannic acid and copper acetate are added into water to be stirred, and a copper-tannic acid pre-coordination solution is obtained; then adding L-lysine into the mixture, and stirring for reaction to obtain precursor liquid after the reaction is completed; and (2) adding glyoxal into the precursor liquid for reaction, and then adding dialdehyde polyethylene glycol for continuous reaction to obtain the compound retarder. The gypsum-based building material comprises the following components: alpha-semi-hydrated gypsum, cement, slag powder, the lysine-tannic acid compound retarder, a water reducing agent and mixing water. The retarder provided by the invention not only has a good retarding effect on the gypsum-based building material, but also can improve the early strength of the gypsum-based building material, and effectively overcomes the contradictory problem of retarding and early strength.

This invention relates to the field of biomedicine, specifically to the application of banana fruit extract in the preparation of anticoagulant or antithrombotic drugs. The banana fruit extract provided by this invention contains flavonoids, polyphenols, polysaccharides, hydroxyanthraquinones, triterpenoids, and other components. Flavonoids and polyphenols have been widely proven to have anti-inflammatory and antioxidant effects, which can synergistically enhance the anticoagulant effect. The high potassium content of banana fruit can indirectly improve vascular function by regulating sodium-potassium balance. The banana fruit extract provided by this invention can inhibit platelet production or promote platelet metabolism, prolong clotting time, and inhibit platelet aggregation. Its natural plant components interfere with platelet aggregation by inhibiting the production of thromboxane A2, achieving anticoagulant and antithrombotic effects. The mechanism of action of banana fruit extract differs from traditional anticoagulants such as heparin, reducing the risk of bleeding. Its natural component characteristics provide a direction for the development of novel plant-derived anticoagulant drugs.

The present invention relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI ("Factor XIa"), and pharmaceutical compositions and methods of treatment comprising the same.

The present invention relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI ("Factor XIa"), and pharmaceutical compositions and methods of treatment comprising the same.

The application discloses a super-long-time slump-retaining concrete, which comprises a cementitious material system, a light aggregate system, a composite admixture system and water; the components and their dosages in each cubic meter of the concrete include: the cementitious material system 400-450 kg, the light aggregate system 1200-1400 kg, the water 200-220 kg, and the composite admixture system 2.0-3.0% of the mass of the cementitious material system; wherein the cementitious material system takes phosphogypsum, cement, mineral powder, glass microbeads and microsilica powder as main raw materials; and the composite admixture system takes a phosphoric acid group modified retarding type polycarboxylate water reducer, a water-retention and thickening component, an alkali-activated component, an air entraining agent and water as main raw materials. The setting time of the concrete can reach 100-120 h, and the mix can still maintain good workability after 72 h, so that the realization of synchronous cutting and pouring concrete continuous wall process and the like can be effectively ensured, and the application is suitable for popularization and application.

The utility model relates to the field of casting production and manufacturing, in particular to a hollow volute which comprises a volute body formed by integral casting, and the volute body comprises a middle hole body, a runner body and an exhaust body. A hollow hole is formed in the middle of the volute body. A mold for a hollow volute comprises an outer shell core, an inner channel core and a middle core, and the two ends of the middle core are connected with the inner wall face of the outer shell core. And the feeding hole is formed in the shell core. A hollow hole is formed in the middle of the poured volute, the overall weight of the volute is reduced, and the volute is light.

This invention discloses a method for preparing a six-element master alloy of aluminum, titanium, tin, zirconium, molybdenum, and chromium, comprising the following steps: Step S1, thoroughly mixing an appropriate amount of potassium chlorate (a heating agent) with aluminum powder, titanium dioxide, tin dioxide, zirconium dioxide, molybdenum trioxide, chromium trioxide, and a slagging agent; Step S2, loading the uniformly mixed materials into a reaction vessel, performing a compaction treatment, and then igniting the mixture. The resulting molten alloy sinks, while slag used to protect the molten alloy floats to the surface. After cooling, the molten alloy yields an initial aluminum-titanium-tin-zirconium-molybdenum-chromium alloy block; Step S3, the alloy block is refined and crushed to obtain the aluminum-titanium-tin-zirconium-molybdenum-chromium master alloy. The method for preparing the six-element master alloy of aluminum, titanium, tin, zirconium, molybdenum, and chromium provided by this invention achieves a one-time preparation through a self-propagating reaction, resulting in a more uniform alloy composition. This effectively improves the alloying degree of TC17 and Ti1000, prevents component segregation and inclusions, and enhances the performance of titanium alloys such as TC17 and Ti1000. This invention also provides an aluminum-titanium-tin-zirconium-molybdenum-chromium master alloy prepared by the above method.

The present invention relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI ("Factor XIa"), and pharmaceutical compositions and methods of treatment comprising the same.

The application discloses a kind of quick repair mortar and preparation method thereof, according to weight fraction, quick repair mortar raw materials include coating modified magnesium oxide 300-500 parts, phosphate 100-150 parts, setting regulator 0-50 parts, quartz sand 300-600 parts, finely ground admixture 60-100 parts, rheological agent 5-20 parts.Each powder is mixed uniformly, and a proper amount of mixing water is added to stir uniformly and can be used.The application can reduce the reactivity of magnesium oxide at a lower calcination temperature by surface coating modification of magnesium oxide particles, thereby prolonging the operable time of magnesium phosphate cement-based repair material, and forming an in-situ polymer modified layer on the surface of magnesium oxide particles, enhancing the bonding performance of magnesium phosphate gel with other powders and aggregates.In addition, the application can utilize red mud, nickel slag and other harmful solid waste as resources, and the aluminum phase and iron phase can react with phosphate to form new mineral phases, improving the mechanical and durability properties of magnesium phosphate materials.

The utility model discloses a mother alloy ingot casting riser which comprises a riser body, the riser body is composed of a heating layer, a fireproof layer and an anti-sticking layer in sequence from inside to outside, the inner side wall of the fireproof layer is coated with the heating layer, the outer side wall of the fireproof layer is coated with the anti-sticking layer, a liquid storage cavity is formed in the riser body, an inlet is formed below the liquid storage cavity, and the inlet is communicated with the liquid storage cavity. A top opening is formed above the liquid storage cavity, and a floating plate for sealing the top opening is placed at an inlet; according to the utility model, the heat distribution is more uniform, the shrinkage cavities are concentrated in the riser instead of the cast ingot body, the necking structure is convenient for subsequent cutting and removal, the casting body is prevented from being damaged during cutting, the heat distribution is more uniform, the shrinkage cavities are concentrated in the riser instead of the cast ingot body, and the necking structure is convenient for subsequent cutting and removal. Meanwhile, the casting body is prevented from being damaged during cutting.

The application discloses a kind of gradient hierarchical utilization garbage incineration bottom ash preparation's zero clinker ultra-high performance concrete and its preparation method, including following weight parts raw materials: garbage incineration bottom ash 660-700 parts;Mineral powder 460-500 parts;Silica fume 35-45 parts;Fine quartz sand 380-420 parts;Activator 370-380 parts;Modifier 15-17 parts;Steel fiber 110-130 parts.Garbage incineration bottom ash includes following particle size and weight parts garbage incineration bottom ash: 8 μm below garbage incineration bottom ash 35-45 parts;8-40 μm garbage incineration bottom ash 75-85 parts;40-150 μm garbage incineration bottom ash 150-170 parts;150-500 μm garbage incineration bottom ash 380-420 parts.The application cooperates and utilizes garbage incineration bottom ash, mineral powder and silica fume, and does not use Portland cement as UHPC cementing material raw material, and UHPC preparation cost and carbon emission are greatly reduced.

The application discloses an organic alkali-activated geopolymer solidified product, a preparation method and application thereof, and relates to the field of geopolymer solidified products.The method comprises the following steps: adding water glass, a surfactant and a defoaming agent into water, uniformly stirring and heating to obtain a micelle solution, and cooling to room temperature for standby use; wherein the water glass accounts for 10-40.33% of the weight percentage of water, the surfactant accounts for 1-7.14% of the weight percentage of water, and the defoaming agent accounts for 0.17-1% of the weight percentage of water; adding an organic alkali into the micelle solution, uniformly mixing to obtain a mixed solution; wherein the organic alkali accounts for 1.83-11.67% of the weight percentage of water; according to the water-glass ratio of 0.3-0.35, fly ash is weighed and poured into a stirring pot of a cement mortar stirrer, the mixed solution is poured into the stirring pot and stirred and mixed to prepare the organic alkali-activated geopolymer solidified product. Not only the "frosting" phenomenon is avoided, but also the compressive strength performance of the organic alkali-activated geopolymer solidified product is significantly improved, which has very great practical significance for widening the application field of geopolymer.